Cocaine- and amphetamine-regulated transcript is localized in pituitary lactotropes and is regulated during lactation

Endocrinology

Volumn 147, Issue 3, 2006, Pages 1213-1223

  Smith, Sean M ^a   Vaughan, Joan M ^a   Donaldson, Cynthia J ^a   Fernandez, Rosette E ^a   Li, Chien ^a   Chen, Alon ^a   Vale, Wylie W ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCRIPTINE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; OXYTOCIN; VASOPRESSIN;

ADENOHYPOPHYSIS; ADRENAL GLAND; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN; CELL POPULATION; CONTROLLED STUDY; FEEDING; FEMALE; GENE CONTROL; GENE LOCATION; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTESTINE; LACTATION; MALE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SUPRAOPTIC NUCLEUS;

AMPHETAMINES; ANIMALS; BROMOCRIPTINE; CELLS, CULTURED; CHROMATOGRAPHY; CHROMATOGRAPHY, GEL; COCAINE; FEMALE; GENE EXPRESSION REGULATION; HYPOTHALAMUS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LACTATION; MALE; MODELS, STATISTICAL; NERVE TISSUE PROTEINS; NEURONS; OXYTOCIN; PITUITARY GLAND; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TISSUE DISTRIBUTION;

EID: 32644448576     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2005-1392     Document Type: Article

References (50)

1. Douglass J, McKinzie AA, Couceyro P 1995 PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J Neurosci 15:2471-2481
2. Adams LD, Gong W, Vechia SD, Hunter RG, Kuhar MJ 1999 CART: from gene to function. Brain Res 848:137-140
3. Kristensen P, Judge ME, Thim L, Ribel U, Christjansen KN, Wulff BS, Clausen JT, Jensen PB, Madsen OD, Vrang N, Larsen PJ, Hastrup S 1998 Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393:72-76
4. Lambert PD, Couceyro PR, McGirr KM, Dall Vechia SE, Smith Y, Kuhar MJ 1998 CART peptides in the central control of feeding and interactions with neuropeptide Y. Synapse 29:293-298
5. Kuhar MJ, Dall Vechia SE 1999 CART peptides: novel addiction- and feeding-related neuropeptides. Trends Neurosci 22:316-320
6. Kuhar MJ, Adams S, Dominguez G, Jaworski J, Balkan B 2002 CART peptides. Neuropeptides 36:1-8
7. Smith SM, Vaughan JM, Donaldson CJ, Rivier J, Li C, Chen A, Vale WW 2004 Cocaine- and amphetamine-regulated transcript activates the hypothalamic- pituitary-adrenal axis through a corticotropin-releasing factor receptor-dependent mechanism. Endocrinology 145:5202-5209
8. Thim L, Kristensen P, Nielsen PF, Wulff BS, Clausen JT 1999 Tissue-specific processing of cocaine- and amphetamine-regulated transcript peptides in the rat. Proc Natl Acad Sci USA 96:2722-2727
9. Wierup N, Kuhar M, Nilsson BO, Mulder H, Ekblad E, Sundler F 2004 Cocaine- and amphetamine-regulated transcript (CART) is expressed in several islet cell types during rat development. J Histochem Cytochem 52:169-177
10. Elias CF, Lee CE, Kelly JF, Ahima RS, Kuhar M, Saper CB, Elmquist JK 2001 Characterization of CART neurons in the rat and human hypothalamus. J Comp Neurol 432:1-19
11. Koylu EO, Couceyro PR, Lambert PD, Ling NC, DeSouza EB, Kuhar MJ 1997 Immunohistochemical localization of novel CART peptides in rat hypothalamus, pituitary and adrenal gland. J Neuroendocrinol 9:823-833
12. Ekblad E, Kuhar M, Wierup N, Sundler F 2003 Cocaine- and amphetamine-regulated transcript: distribution and function in rat gastrointestinal tract. Neurogastroenterol Motil 15:545-557
13. Wittmann G LZ, Lechan RM, Fekete C 2005 Origin of cocaine- and amphetamine-regulated transcript (CART)-containing axons innervating hypophysiotropic corticotropin-releasing hormone (CRH)-synthesizing neurons in the rat. Endocrinology 146:2985-2991
14. Vrang N, Larsen PJ, Clausen JT, Kristensen P 1999 Neurochemical characterization of hypothalamic cocaine-amphetamine-regulated transcript neurons. J Neurosci 19:RC5
15. Fekete C, Mihaly E, Luo LG, Kelly J, Clausen JT, Mao Q, Rand WM, Moss LG, Kuhar M, Emerson CH, Jackson IM, Lechan RM 2000 Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. J Neurosci 20:9224-9234
16. Kozicz T 2003 Neurons colocalizing urocortin and cocaine and amphetamine-regulated transcript immunoreactivities are induced by acute lipopolysaccharide stress in the Edinger-Westphal nucleus in the rat. Neuroscience 116:315-320
17. Murphy KG, Abbott CR, Mahmoudi M, Hunter R, Gardiner JV, Rossi M, Stanley SA, Ghatei MA, Kuhar MJ, Bloom SR 2000 Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues. J Endocrinol 166:659-668
18. Kuriyama G, Takekoshi S, Tojo K, Nakai Y, Kuhar MJ, Osamura RY 2004 CART Peptide in the rat anterior pituitary gland is localized in gonadotrophs and suppresses prolactin secretion. Endocrinology 145:2542-2550
19. Stanley SA, Murphy KG, Bewick GA, Kong WM, Opacka-Juffry J, Gardiner JV, Ghatei M, Small CJ, Bloom SR 2004 Regulation of rat pituitary cocaine- and amphetamine-regulated transcript (CART) by CRH and glucocorticoids. Am J Physiol 287:E583-E590
20. Vaughan JM, Rivier J, Corrigan AZ, McClintock R, Campen CA, Jolley D, Voglmayr JK, Bardin CW, Rivier C, Vale W 1989 Detection and purification of inhibin using antisera generated against synthetic peptide fragments. Methods Enzymol 168:588-617
21. Gulyas J, Rivier C, Perrin M, Koerber SC, Sutton S, Corrigan A, Lahrichi SL, Craig AG, Vale W, Rivier J 1995 Potent, structurally constrained agonists and competitive antagonists of corticotropin-releasing factor. Proc Natl Acad Sci USA 92:10575-105759
22. Vale W, Vaughan J, Yamamoto G, Bruhn T, Douglas C, Dalton D, Rivier C, Rivier J 1983 Assay of corticotropin releasing factor. Methods Enzymol 103:565-577
23. Kageyama K, Li C, Vale WW 2003 Corticotropin-releasing factor receptor type 2 messenger ribonucleic acid in rat pituitary: localization and regulation by immune challenge, restraint stress, and glucocorticoids. Endocrinology 144:1524-1532
24. Buhimschi CS 2004 Endocrinology of lactation. Obstet Gynecol Clin North Am 31:963-979
25. Vicentic A, Dominguez G, Hunter RG, Philpot K, Wilson M, Kuhar MJ 2004 Cocaine- and amphetamine-regulated transcript peptide levels in blood exhibit a diurnal rhythm: regulation by glucocorticoids. Endocrinology 145:4119-4124
26. Vrang N, Larsen PJ, Kristensen P, Tang-Christensen M 2000 Central administration of cocaine-amphetamine-regulated transcript activates hypothalamic neuroendocrine neurons in the rat. Endocrinology 141:794-801
27. Stanley SA, Small CJ, Murphy KG, Rayes E, Abbott CR, Seal LJ, Morgan DG, Sunter D, Dakin CL, Kim MS, Hunter R, Kuhar M, Ghatei MA, Bloom SR 2001 Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo-pituitary axes in vitro and in vivo in male rats. Brain Res 893:186-194
28. Vrang N, Larsen PJ, Tang-Christensen M, Larsen LK, Kristensen P 2003 Hypothalamic cocaine-amphetamine regulated transcript (CART) is regulated by glucocorticoids. Brain Res 965:45-50
29. Dallvechia-Adams S, Smith Y, Kuhar MJ 2001 CART peptide-immunoreactive projection from the nucleus accumbens targets substantia nigra pars reticulata neurons in the rat. J Comp Neurol 434:29-39
30. Koylu EO, Couceyro PR, Lambert PD, Kuhar MJ 1998 Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain. J Comp Neurol 391:115-132
31. Fekete C, Wittmann G, Liposits Z, Lechan RM 2004 Origin of cocaine- and amphetamine-regulated transcript (CART)-immunoreactive innervation of the hypothalamic paraventricular nucleus. J Comp Neurol 469:340-350
32. Kuhar MJ, Yoho LL 1999 CART peptide analysis by Western blotting. Synapse 33:163-171
33. Barrett P, Morris MA, Moar KM, Mercer JG, Davidson JA, Findlay PA, Adam CL, Morgan PJ 2001 The differential regulation of CART gene expression in a pituitary cell line and primary cell cultures of ovine pars tuberalis cells. J Neuroendocrinol 13:347-352
34. Dominguez G, Lakatos A, Kuhar MJ 2002 Characterization of the cocaine- and amphetamine-regulated transcript (CART) peptide gene promoter and its activation by a cyclic AMP-dependent signaling pathway in GH3 cells. J Neurochem 80:885-893
35. Tashjian Jr AH, Yasumura Y, Levine L, Sato GH, Parker ML 1968 Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone. Endocrinology 82:342-352
36. Vandesande F, Dierickx K 1975 Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalamic magnocellular neurosecretory system of the rat. Cell Tissue Res 164:153-162
37. Larsen PJ, Seier V, Fink-Jensen A, Holst JJ, Warberg J, Vrang N 2003 Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit. J Neuroendocrinol 15:219-226
38. Meites J 1977 Neuroendocrine control of prolactin in experimental animals. Clin Endocrinol (Oxf) 6(Suppl):9S-18S
39. MacLeod RM, Lehmeyer JE 1974 Studies on the mechanism of the dopamine-mediated inhibition of prolactin secretion. Endocrinology 94:1077-1085
40. Ruberg M, Enjalbert A, Arancibia S, Kordon C 1981 Regulation of prolactin secretion at the pituitary level. Exp Brain Res(Suppl 3):182-199
41. Albert PR, Neve KA, Bunzow JR, Civelli O 1990 Coupling of a cloned rat dopamine-D2 receptor to inhibition of adenylyl cyclase and prolactin secretion. J Biol Chem 265:2098-2104
42. Jaffe RB, Yuen BH, Keye Jr WR, Midgley Jr AR 1973 Physiologic and pathologic profiles of circulating human prolactin. Am J Obstet Gynecol 117:757-773
43. Nishimori K, Young LJ, Guo Q, Wang Z, Insel TR, Matzuk MM 1996 Oxytocin is required for nursing but is not essential for parturition or reproductive behavior. Proc Natl Acad Sci USA 93:11699-11704
44. Samson WK, Taylor MM, Baker JR 2003 Prolactin-releasing peptides. Regul Pept 114:1-5
45. Samson WK, Said SI, Snyder G, McCann SM 1980 In vitro stimulation of prolactin release by vasoactive intestinal peptide. Peptides 1:325-332
46. Samson WK, Lumpkin MD, McCann SM 1986 Evidence for a physiological role for oxytocin in the control of prolactin secretion. Endocrinology 119:554-560
47. Lamberts SW, Macleod RM 1990 Regulation of prolactin secretion at the level of the lactotroph. Physiol Rev 70:279-318
48. Kanyicska B, Sellix MT, Freeman ME 2001 Autocrine regulation of prolactin secretion by endothelins: a permissive role for estradiol. Endocrine 16:133-137
49. Raptis S, Fekete C, Sarkar S, Rand WM, Emerson CH, Nagy GM, Lechan RM 2004 Cocaine- and amphetamine-regulated transcript co-contained in thyrotropin-releasing hormone (TRH) neurons of the hypothalamic paraventricular nucleus modulates TRH-induced prolactin secretion. Endocrinology 145:1695-1699
50. Lamote I, Meyer E, Massart-Leen AM, Burvenich C 2004 Sex steroids and growth factors in the regulation of mammary gland proliferation, differentiation, and involution. Steroids 69:145-159