Aging does not aggravate the pregnancy-induced adaptations in glucose tolerance in rats

Metabolism: Clinical and Experimental

Volumn 55, Issue 3, 2006, Pages 409-414

  Caluwaerts, Silvia ^a   Holemans, Kathleen ^a   Van Bree, Rita ^a   Verhaeghe, Johan ^a   Van Assche, F André ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FAT; GLUCOSE; LEPTIN; LIPID; TRIACYLGLYCEROL;

ADAPTATION; AGING; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FETUS (ANATOMY); FETUS WEIGHT; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; INTRAVENOUS GLUCOSE TOLERANCE TEST; LIPID METABOLISM; MATERNAL DIABETES MELLITUS; MEDICAL PARAMETERS; NONHUMAN; PERFORMANCE; PLACENTA WEIGHT; PREGNANCY; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE ANALYSIS; RAT; REPRODUCTION; TRIACYLGLYCEROL BLOOD LEVEL;

ADAPTATION, BIOLOGICAL; ADIPOSITY; AGING; ANIMALS; AREA UNDER CURVE; BLOOD GLUCOSE; FEMALE; GLUCOSE TOLERANCE TEST; INSULIN; LEPTIN; LIPIDS; PREGNANCY; RATS; RATS, WISTAR;

EID: 32544461760     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2005.10.001     Document Type: Article

References (35)

1. S.J. Ventura, B.E. Hamilton, and P.D. Sutton Revised birth and fertility rates for the United States, 2000 and 2001 Natl Vital Stat Rep 51 2003 [National Center for Health Statistics]
2. M. Prysak, R.P. Lorenz, and A. Kisly Pregnancy outcome in nulliparous women 35 years and older Obstet Gynecol 85 1995 65 70
3. C.G. Solomon, W.C. Willett, and V.J. Carey A prospective study of pregravid determinants of gestational diabetes mellitus JAMA 278 1997 1078 1083
4. R.J. Paulson, R. Boostanfar, and P. Saadat Pregnancy in the sixth decade of life; obstetric outcomes in women of advanced reproductive age JAMA 288 2002 2320 2323
5. R. Basu, E. Breda, and A.L. Oberg Mechanisms of the age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance Diabetes 52 2003 1738 1748
6. P. Iozzo, H. Beck-Nielsen, and M. Laakso Independent influence of age on basal insulin secretion in nondiabetic humans J Clin Endocrinol Metab 84 1999 863 868
7. F. Escriva, M. Agote, and E. Rubio In vivo insulin-dependent glucose uptake of specific tissues is decreased during aging of mature Wistar rats Endocrinology 138 1997 49 54
8. M. Novelli, V. De Tata, and M. Bombara Age-dependent reduction in GLUT-2 levels is correlated with the impairment of the insulin secretory response in isolated islets of Sprague-Dawley rats Exp Gerontol 35 2000 641 651
9. C. Remacle, L. De Clercq, and P. Delaère Organ culture of islets of Langerhans from young and senescent rats Cell Tissue Res 207 1980 429 448
10. N.T. Lam, A.T. Cheung, and M.J. Riedel Leptin reduces glucose transport and cellular ATP levels in INS-1 beta-cells J Mol Endocrinol 32 2004 415 424
11. P.C. Tsiotra, C. Tsigos, and S.A. Raptis TNFalpha and leptin inhibit basal and glucose-stimulated insulin secretion and gene transcription in the HIT-T15 pancreatic cells Int J Obes Relat Metab Disord 25 2001 1018 1026
12. N. Freinkel Banting lecture 1980. Of pregnancy and progeny Diabetes 29 1980 1023 1035
13. A.H. Xiang, R.K. Peters, and E. Trigo Multiple metabolic defects during late pregnancy in women at high risk for type 2 diabetes Diabetes 48 1999 848 854
14. A. Leturque, A.F. Burnol, and P. Ferré Pregnancy-induced insulin resistance in the rat: assessment by glucose clamp technique Am J Physiol 246 1984 E25 E31
15. A.J. Bone, and K.W. Taylor Metabolic adaptations to pregnancy shown by increased biosynthesis of insulin in islets of Langerhans isolated from pregnant rats Nature 262 1976 501 502
16. R.K. Kalkhoff, and H.J. Kim Effects of pregnancy on insulin and glucagon secretion by perifused rat pancreatic islets Endocrinology 102 1978 623 631
17. L. Aerts, and F.A. Van Assche Ultrastructural changes of the endocrine pancreas in pregnant rats Diabetologia 11 1975 285 289
18. W.M. Kohrt, J.P. Kirwan, and M.A. Staten Insulin resistance in aging is related to abdominal obesity Diabetes 42 1993 273 281
19. I. Gabriely, X.H. Ma, and X.M. Yang Removal of visceral fat prevents insulin resistance and glucose tolerance of aging Diabetes 51 2002 2951 2958
20. H. Li, M. Matheny, and M. Nicolson Leptin gene expression increases with age independent of increasing adiposity in rats Diabetes 46 1997 2035 2039
21. I. Gabriely, X.H. Ma, and X.M. Yang Leptin resistance during aging is independent of fat mass Diabetes 51 2002 1016 1021
22. J.W. Kolaczynski, M.R. Nyce, and R.V. Considine Acute and chronic effects of insulin on leptin production in humans: studies in vivo and in vitro Diabetes 45 1996 699 701
23. T.J. Kieffer, R.S. Heller, and J.F. Habener Leptin receptors expressed on pancreatic beta-cells Biochem Biophys Res Commun 224 1996 522 527
24. V. Emilsson, Y.L. Liu, and M.A. Cawthorne Expression of the functional leptin receptor mRNA in pancreatic islets and direct inhibitory action of leptin on insulin secretion Diabetes 46 1997 313 316
25. J. Seufert, T.J. Kieffer, and C.A. Leech Leptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus J Clin Endocrinol Metab 84 1999 670 676
26. T.J. Kieffer, and J.F. Habener The adipoinsular axis: effects of leptin on pancreatic β-cells Am J Physiol Endocrinol Metab 278 2000 E1 E14
27. M.H. Vickers, S. Reddy, and B.A. Ikenasio Dysregulation of the adipoinsular axis-a mechanism for the pathogenesis of hyperleptinemia and adipogenic diabetes induced by fetal programming J Endocrinol 170 2001 323 332
28. C. Stocker, J. O'Dowd, and N.M. Morton Modulation of susceptibility to weight gain and insulin resistance in low birthweight rats by treatment of their mothers with leptin during pregnancy and lactation Int J Obes 28 2004 129 136
29. H. Masuzaki, Y. Ogawa, and N. Sagawa Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans Nat Med 3 1997 1029 1033
30. E. Herrera, M.A. Lasuncion, and L. Huerta Plasma leptin levels in rat mother and offspring during pregnancy and lactation Biol Neonate 78 2000 315 320
31. Y. Tereda, K. Yamakawa, and A. Sugaya Serum leptin levels do not rise during pregnancy in age-matched rats Biochem Biophys Res Commun 253 1998 841 844
32. M. Kawai, M. Yamaguchi, and T. Murakami The placenta is not the main source of leptin production in pregnant rat: gestational profile of leptin in plasma and adipose tissues Biochem Biophys Res Commun 240 1997 798 802
33. P. Wentzel, L. Jansson, and U.J. Eriksson Diabetes in pregnancy: uterine blood flow and embryonic development in the rat Pediatr Res 38 1995 598 606
34. E. Wight, C.F. Küng, and P. Moreau Aging, serum estradiol levels, and pregnancy differentially affect vascular reactivity of the rat uterine artery J Soc Gynecol Investig 7 2000 106 113
35. O.W. van der Heijden, Y.P. Essers, and L.H. Simkens Aging blunts remodeling of the uterine artery during murine pregnancy J Soc Gynecol Investig 11 2004 304 310