-
1
-
-
0025240615
-
The pattern of mutational involvement of ras genes in human haematologic malignancies determined by DNA amplification and direct sequencing
-
Ahuja, H., Foti, A., Bar-Eli, M. & Cline, M.J., (1990) The pattern of mutational involvement of ras genes in human haematologic malignancies determined by DNA amplification and direct sequencing. Blood, 75, 1684-1690.
-
(1990)
Blood
, vol.75
, pp. 1684-1690
-
-
Ahuja, H.1
Foti, A.2
Bar-Eli, M.3
Cline, M.J.4
-
4
-
-
0022137480
-
Microinjection of the ras oncogene protein in PC12 cells induces morphological differentiation
-
Bar-Sagi, M. & Feramisco, J.R. (1985) Microinjection of the ras oncogene protein in PC12 cells induces morphological differentiation. Cell, 42, 841-848.
-
(1985)
Cell
, vol.42
, pp. 841-848
-
-
Bar-Sagi, M.1
Feramisco, J.R.2
-
5
-
-
0026500545
-
Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML)
-
Bashey, A., Gill, R., Levi, S., Farr, C., Clutterbuck, R., Millar, J., Pragnell, I. & Marshall, C. (1992) Mutational activation of the N-ras oncogene assessed in primary clonogenic culture of acute myeloid leukemia (AML). Blood, 79, 981-989.
-
(1992)
Blood
, vol.79
, pp. 981-989
-
-
Bashey, A.1
Gill, R.2
Levi, S.3
Farr, C.4
Clutterbuck, R.5
Millar, J.6
Pragnell, I.7
Marshall, C.8
-
6
-
-
9044251606
-
Loss of NF1 results in activation of the Ras signalling pathway and leads to aberrant growth in haemopoietic cells
-
Bollag, G., Clapp, D.W., Shih, S., Adler, F., Zhang, Y.Y. & Thompson, P. (1996) Loss of NF1 results in activation of the Ras signalling pathway and leads to aberrant growth in haemopoietic cells. Nature Genetics, 12, 144-148.
-
(1996)
Nature Genetics
, vol.12
, pp. 144-148
-
-
Bollag, G.1
Clapp, D.W.2
Shih, S.3
Adler, F.4
Zhang, Y.Y.5
Thompson, P.6
-
7
-
-
0021871489
-
Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia
-
Bos, J.L., Toksoz, D., Marshall, C.J., Verlaan-de Vries, M., Veeneman, G.H., van der Eb, A.J., van Bloom, J.H., Janssen, J.W.G. & Steenvoorden, A.C.M. (1985) Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia. Nature, 315, 726-730.
-
(1985)
Nature
, vol.315
, pp. 726-730
-
-
Bos, J.L.1
Toksoz, D.2
Marshall, C.J.3
Verlaan-de Vries, M.4
Veeneman, G.H.5
Van Der Eb, A.J.6
Van Bloom, J.H.7
Janssen, J.W.G.8
Steenvoorden, A.C.M.9
-
8
-
-
0023160529
-
Mutations in N-ras predominate in acute leukemia
-
Bos, J.L., Verlaan-de Vries, M., van der Eb, A.J., Janssen, J.W.G., Delwel, R., Lowenberg, B. & Colley, L.P. (1987) Mutations in N-ras predominate in acute leukemia. Blood, 69, 1237-1241.
-
(1987)
Blood
, vol.69
, pp. 1237-1241
-
-
Bos, J.L.1
Verlaan-de Vries, M.2
Van Der Eb, A.J.3
Janssen, J.W.G.4
Delwel, R.5
Lowenberg, B.6
Colley, L.P.7
-
9
-
-
6844263667
-
Alterations of Ras expression in human leukemia cells induced by farnesyl pyrophosphate analogues
-
Buntinas, R., Lewis-Tibesar, K., Pogatchnik, D., Wiemer, D. & Hohl, R. (1996) Alterations of Ras expression in human leukemia cells induced by farnesyl pyrophosphate analogues. Blood, 88, (Suppl. 1), 822a.
-
(1996)
Blood
, vol.88
, Issue.1 SUPPL.
-
-
Buntinas, R.1
Lewis-Tibesar, K.2
Pogatchnik, D.3
Wiemer, D.4
Hohl, R.5
-
10
-
-
0029160069
-
Protein kinase B (cAkt) in phosphatidylinositol 3 OH kinase signal transduction
-
Burgering, B. & Coffer, P. (1995) Protein kinase B (cAkt) in phosphatidylinositol 3 OH kinase signal transduction. Nature, 376, 599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.1
Coffer, P.2
-
11
-
-
0027339924
-
Increased levels of p21ras GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62 in c-src overexpressors
-
Chang, J.H., Wilson, L.K., Moyers, J.S., Zhang, K. & Parsons, S.J. (1993) Increased levels of p21ras GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62 in c-src overexpressors. Oncogene, 8, 959-967.
-
(1993)
Oncogene
, vol.8
, pp. 959-967
-
-
Chang, J.H.1
Wilson, L.K.2
Moyers, J.S.3
Zhang, K.4
Parsons, S.J.5
-
12
-
-
0030821826
-
Role of CED-4 in the activation of CED-3
-
Chinnaiyan, A., Chaudhary, D., O'Rourke, K., Koonin, E. & Dixit, V. (1997) Role of CED-4 in the activation of CED-3. Nature, 388, 728-729.
-
(1997)
Nature
, vol.388
, pp. 728-729
-
-
Chinnaiyan, A.1
Chaudhary, D.2
O'Rourke, K.3
Koonin, E.4
Dixit, V.5
-
13
-
-
0028114788
-
The incidence and prognostic significance of mutations in codon 13 of the N-RAS gene in acute myeloid leukemia
-
Coghlan, D., Morley, A.A.., Matthews, L. & Bishop, J. (1994) The incidence and prognostic significance of mutations in codon 13 of the N-RAS gene in acute myeloid leukemia. Leukemia, 8, 1682-1687.
-
(1994)
Leukemia
, vol.8
, pp. 1682-1687
-
-
Coghlan, D.1
Morley, A.A.2
Matthews, L.3
Bishop, J.4
-
14
-
-
0024316910
-
Mutations of the ras protooncogenes in chronic myelogenous leukemia: A high frequency of ras mutations in bcr/abl rearrangement-negative chronic myelogenous leukemia
-
Cogswell, P.C., Morgan, R., Dunn, M., Neubauer, A., Nelson, P., Poland-Johnston, N.K., Sandberg, A.A. & Liu, E. (1989) Mutations of the ras protooncogenes in chronic myelogenous leukemia: a high frequency of ras mutations in bcr/abl rearrangement-negative chronic myelogenous leukemia. Blood, 74, 2629-2633.
-
(1989)
Blood
, vol.74
, pp. 2629-2633
-
-
Cogswell, P.C.1
Morgan, R.2
Dunn, M.3
Neubauer, A.4
Nelson, P.5
Poland-Johnston, N.K.6
Sandberg, A.A.7
Liu, E.8
-
15
-
-
0028980342
-
Structural and signalling requirements for BCR-ABL mediated transformation and inhibition of apoptosis
-
Cortez, D., Kadlec, L. & Pendergast, A. (1995) Structural and signalling requirements for BCR-ABL mediated transformation and inhibition of apoptosis. Molecular and Cellular Biology, 15, 5531-5541.
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 5531-5541
-
-
Cortez, D.1
Kadlec, L.2
Pendergast, A.3
-
16
-
-
0027422247
-
The pathway to signal achievement
-
Egan, S. & Weinberg, R. (1993) The pathway to signal achievement. Nature, 365, 781-783.
-
(1993)
Nature
, vol.365
, pp. 781-783
-
-
Egan, S.1
Weinberg, R.2
-
17
-
-
0020624302
-
Transforming genes of human hematopoietic tumors: Frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype
-
Eva, A., Tronick, S.R., Gol, R.A., Pierce, J.H. & Aaronson, S.A (1993) Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype. Proceedings of the National Academy of Sciences of the United States of America, 80, 4926-4930.
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.80
, pp. 4926-4930
-
-
Eva, A.1
Tronick, S.R.2
Gol, R.A.3
Pierce, J.H.4
Aaronson, S.A.5
-
18
-
-
0023880245
-
Analysis of ras gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes
-
Farr, C.J., Saiki, R.K., Erlich, H.A., McCormick, F. & Marshall, C.J. (1988) Analysis of ras gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes. Proceedings of the National Academy of Sciences of the United States of America, 85, 1629-1633.
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, pp. 1629-1633
-
-
Farr, C.J.1
Saiki, R.K.2
Erlich, H.A.3
McCormick, F.4
Marshall, C.J.5
-
19
-
-
0021719520
-
Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells
-
Feramisco, J.R., Gross, M., Kamata, T., Rosenberg, M. & Sweet, R. (1984) Microinjection of the oncogene form of the human H-ras (T-24) protein results in rapid proliferation of quiescent cells. Cell, 38, 109-117.
-
(1984)
Cell
, vol.38
, pp. 109-117
-
-
Feramisco, J.R.1
Gross, M.2
Kamata, T.3
Rosenberg, M.4
Sweet, R.5
-
20
-
-
0018778825
-
Acute nonlymphocytic leukemia: Expression in cells restricted to granulocytic and monocytic differentiation
-
Fialkow, P.J., Singer, J.W., Adamson, J.W., Berkow, R.L., Friedman, J.M., Jacobson, R.J. & Moohr, J.W (1979) Acute nonlymphocytic leukemia: expression in cells restricted to granulocytic and monocytic differentiation. New England Journal of Medicine, 301, 1-5.
-
(1979)
New England Journal of Medicine
, vol.301
, pp. 1-5
-
-
Fialkow, P.J.1
Singer, J.W.2
Adamson, J.W.3
Berkow, R.L.4
Friedman, J.M.5
Jacobson, R.J.6
Moohr, J.W.7
-
21
-
-
0029079275
-
The protein kinase encoded by the Akt protooncogene is a target of the PDGF-activated phosphatidylinositol 3 kinase
-
Franke, T., Yang, S., Chan, T., Data, K., Kazlauskas, A., Morrison, D., Kaplan, D. & Tsichlis, P.N. (1996) The protein kinase encoded by the Akt protooncogene is a target of the PDGF-activated phosphatidylinositol 3 kinase. Cell, 81, 727-736.
-
(1996)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.1
Yang, S.2
Chan, T.3
Data, K.4
Kazlauskas, A.5
Morrison, D.6
Kaplan, D.7
Tsichlis, P.N.8
-
22
-
-
0029042689
-
Raf1 interaction with Cdc 25 phosphatase ties mitogenic signal transduction to cell cycle activation
-
Galaktionov, K., Jessus, C. & Beach, D. (1995) Raf1 interaction with Cdc 25 phosphatase ties mitogenic signal transduction to cell cycle activation. Genes and Development, 9, 1046-1058.
-
(1995)
Genes and Development
, vol.9
, pp. 1046-1058
-
-
Galaktionov, K.1
Jessus, C.2
Beach, D.3
-
23
-
-
0028973561
-
Aberrant expression of p21(RAS) but not p120(GAP) is a common feature of myelodysplasia
-
Gallagher, A., Padua, R.A., AlSabah, A., Hoy, T., Burnett, A.K. & Darley, R.L. (1995) Aberrant expression of p21(RAS) but not p120(GAP) is a common feature of myelodysplasia. Leukemia, 9, 1833-1840.
-
(1995)
Leukemia
, vol.9
, pp. 1833-1840
-
-
Gallagher, A.1
Padua, R.A.2
Alsabah, A.3
Hoy, T.4
Burnett, A.K.5
Darley, R.L.6
-
24
-
-
0344815446
-
Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon
-
Gambke, C., Hall, A. & Moroni, C. (1985) Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon. Proceedings of the National Academy of Sciences of the United States of America, 82, 879-882.
-
(1985)
Proceedings of the National Academy of Sciences of the United States of America
, vol.82
, pp. 879-882
-
-
Gambke, C.1
Hall, A.2
Moroni, C.3
-
25
-
-
0028224348
-
Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5:12) chromosomal translocation
-
Golub, T., Barker, G., Lovett, M. & Gilliland, D. (1994) Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5:12) chromosomal translocation. Cell, 77, 307-316.
-
(1994)
Cell
, vol.77
, pp. 307-316
-
-
Golub, T.1
Barker, G.2
Lovett, M.3
Gilliland, D.4
-
26
-
-
0029826228
-
Mutations and expression of the Ras family genes in leukaemias
-
Gougopoulou, D., Kiaris, H., Ergazaki, M., Anagnostopoulos, N., Grigoraki, V. & Spandidos, D. (1996) Mutations and expression of the Ras family genes in leukaemias. Stem Cells, 14, 725-729.
-
(1996)
Stem Cells
, vol.14
, pp. 725-729
-
-
Gougopoulou, D.1
Kiaris, H.2
Ergazaki, M.3
Anagnostopoulos, N.4
Grigoraki, V.5
Spandidos, D.6
-
27
-
-
0040433650
-
Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene
-
Hirakawa, T. & Ruley, H.E. (1988) Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene. Proceedings of the National Academy of Sciences of the United States of America, 85, 1519-1923.
-
(1988)
Proceedings of the National Academy of Sciences of the United States of America
, vol.85
, pp. 1519-1923
-
-
Hirakawa, T.1
Ruley, H.E.2
-
28
-
-
0028818914
-
+ase in v-Src-induced phospholipase D activation
-
+ase in v-Src-induced phospholipase D activation. Nature, 378, 409-412.
-
(1995)
Nature
, vol.378
, pp. 409-412
-
-
Jiang, H.1
Luo, J.-Q.2
Rano, T.3
Frankel, P.4
Lu, Z.5
Foster, D.6
Feig, L.7
-
29
-
-
0028125213
-
Genetic-analysis is consistent with the hypothesis that NF-1 limits myeloid cell growth through p21Ras
-
Kalra, R., Paderanga, D., Olson, K. & Shannon, K. (1994) Genetic-analysis is consistent with the hypothesis that NF-1 limits myeloid cell growth through p21Ras. Blood, 84, 3435-3439.
-
(1994)
Blood
, vol.84
, pp. 3435-3439
-
-
Kalra, R.1
Paderanga, D.2
Olson, K.3
Shannon, K.4
-
30
-
-
0031028730
-
Suppression of c-myc induced apoptosis induced by Ras signalling through PI-3 K and PKB
-
Kauffman-Zeh, A., Rodriguez-Viciana, P., Ulrich, E., Gilbert, C., Coffer, P., Downward, J. & Evan, G. (1997) Suppression of c-myc induced apoptosis induced by Ras signalling through PI-3 K and PKB. Nature, 385, 544-548.
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffman-Zeh, A.1
Rodriguez-Viciana, P.2
Ulrich, E.3
Gilbert, C.4
Coffer, P.5
Downward, J.6
Evan, G.7
-
31
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3 OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja, A., Rodriguez-Viciana, P.S.W., Warne, P.H. & Downward, J. (1997) Matrix adhesion and Ras transformation both activate a phosphoinositide 3 OH kinase and protein kinase B/Akt cellular survival pathway. EMBO Journal, 16, 2783-2793.
-
(1997)
EMBO Journal
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana, P.S.W.2
Warne, P.H.3
Downward, J.4
-
32
-
-
0027986765
-
RalGDS family members interact with the effector loop of ras p21
-
Kikuchi, A., Demo, S.D., Ye, Z.H., Chen, Y.W. & Williams, L.T. (1994) RalGDS family members interact with the effector loop of ras p21. Molecular and Cellular Biology, 14, 7483-7491.
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 7483-7491
-
-
Kikuchi, A.1
Demo, S.D.2
Ye, Z.H.3
Chen, Y.W.4
Williams, L.T.5
-
33
-
-
0029033866
-
Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells
-
Kinoshita, T., Yokota, T., Arai, K. & Miyajima, A. (1995a) Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells. Oncogene, 19, 2207-2212.
-
(1995)
Oncogene
, vol.19
, pp. 2207-2212
-
-
Kinoshita, T.1
Yokota, T.2
Arai, K.3
Miyajima, A.4
-
34
-
-
0028837491
-
Suppression of apoptotic death in haemopoietic cells by signalling through the IL-3/GM-CSF receptors
-
Kinoshita, T., Yokota, T., Arai, K. & Miyajima, A. (1995b) Suppression of apoptotic death in haemopoietic cells by signalling through the IL-3/GM-CSF receptors. EMBO Journal, 14, 266-275.
-
(1995)
EMBO Journal
, vol.14
, pp. 266-275
-
-
Kinoshita, T.1
Yokota, T.2
Arai, K.3
Miyajima, A.4
-
35
-
-
0030045594
-
NF-1 deficiency causes Ras-mediated granulocyte-macrophage colony-stimulating factor hypersensitivity and chronic myeloid leukaemia
-
Largaespada, D., Brannan, C., Jenkins, N. & Copeland, N. (1996) NF-1 deficiency causes Ras-mediated granulocyte-macrophage colony-stimulating factor hypersensitivity and chronic myeloid leukaemia. Nature Genetics, 12, 137-143.
-
(1996)
Nature Genetics
, vol.12
, pp. 137-143
-
-
Largaespada, D.1
Brannan, C.2
Jenkins, N.3
Copeland, N.4
-
36
-
-
0029786329
-
Cyclin D expression is regulated positively by the p42/p44 (MAPK) and negatively by the p38/HOG (MAPK) pathway
-
Lavoie, J., Callemain, G., Brunet, A., Muller, R. & Jones, P. (1996) Cyclin D expression is regulated positively by the p42/p44 (MAPK) and negatively by the p38/HOG (MAPK) pathway. Journal of Biological Chemistry, 271, 20608-20616.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.1
Callemain, G.2
Brunet, A.3
Muller, R.4
Jones, P.5
-
37
-
-
0029088646
-
Analysis of mutations of neurofibromatosis type 1 gene and N-ras gene in acute myelogenous leukemia
-
Lee, Y.Y., Kim, W.S., Bang, Y.J., Jung, C.W., Park, S., Yoon, W.J., Cho, K.S., Kim, I.S., Jung, T.J., Cho, I.Y., Kim, B.K., Kim, N.K. & Koeffler, H.P. (1995) Analysis of mutations of neurofibromatosis type 1 gene and N-ras gene in acute myelogenous leukemia. Stem Cells, 13, 556-563.
-
(1995)
Stem Cells
, vol.13
, pp. 556-563
-
-
Lee, Y.Y.1
Kim, W.S.2
Bang, Y.J.3
Jung, C.W.4
Park, S.5
Yoon, W.J.6
Cho, K.S.7
Kim, I.S.8
Jung, T.J.9
Cho, I.Y.10
Kim, B.K.11
Kim, N.K.12
Koeffler, H.P.13
-
38
-
-
0030995824
-
Myc and ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
-
Leone, G., DeGregori, J., Sears, R., Jakol, L. & Nevins, J. (1997) Myc and ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature, 387, 422-426.
-
(1997)
Nature
, vol.387
, pp. 422-426
-
-
Leone, G.1
Degregori, J.2
Sears, R.3
Jakol, L.4
Nevins, J.5
-
39
-
-
0030950537
-
Cooperative oncogenes converge to regulate cyclin/cdk complexes
-
Lloyd, A., Obermuller, F., Staddon, S., Barth, C., McMahon, M. & Land, H. (1997) Cooperative oncogenes converge to regulate cyclin/cdk complexes. Genes and Development, 11, 663-677.
-
(1997)
Genes and Development
, vol.11
, pp. 663-677
-
-
Lloyd, A.1
Obermuller, F.2
Staddon, S.3
Barth, C.4
McMahon, M.5
Land, H.6
-
40
-
-
0028152333
-
MAP kinase kinase kinase, Map kinase kinase and MAP kinase
-
Marshall, C.J. (1994) MAP kinase kinase kinase, Map kinase kinase and MAP kinase. Current Opinion in Genetics and Development, 4, 82-89.
-
(1994)
Current Opinion in Genetics and Development
, vol.4
, pp. 82-89
-
-
Marshall, C.J.1
-
41
-
-
0028872649
-
Specificity of receptor tyrosine kinase signalling: Transient versus sustained extracellular signal-regulated kinase activation
-
Marshall, C.J (1995) Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signal-regulated kinase activation. Cell, 80, 179-185.
-
(1995)
Cell
, vol.80
, pp. 179-185
-
-
Marshall, C.J.1
-
43
-
-
0031105404
-
Ras signalling is required for inactivation of the tumour suppressor pRb cell cycle control protein
-
Mittnacht, S., Paterson, H., Olson, M. & Marshall, C. (1997) Ras signalling is required for inactivation of the tumour suppressor pRb cell cycle control protein. Current Biology, 7, 219-221.
-
(1997)
Current Biology
, vol.7
, pp. 219-221
-
-
Mittnacht, S.1
Paterson, H.2
Olson, M.3
Marshall, C.4
-
44
-
-
0021970413
-
Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells
-
Mulcahy, L.S., Smith, M.R. & Stacey, D.W. (1985) Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells. Nature, 313, 241-243.
-
(1985)
Nature
, vol.313
, pp. 241-243
-
-
Mulcahy, L.S.1
Smith, M.R.2
Stacey, D.W.3
-
45
-
-
0024378079
-
Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA-sequence
-
Murre, C., Schonleber McCaw, P., Vaessin, H., Caudy, M., Jan, L., Jan, Y., Cabrera, C., Buskin, J., Hauschka, S., Lassar, A., Weintrub, H. & Baltimore, D. (1989) Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA-sequence. Cell, 58, 537-544.
-
(1989)
Cell
, vol.58
, pp. 537-544
-
-
Murre, C.1
Schonleber McCaw, P.2
Vaessin, H.3
Caudy, M.4
Jan, L.5
Jan, Y.6
Cabrera, C.7
Buskin, J.8
Hauschka, S.9
Lassar, A.10
Weintrub, H.11
Baltimore, D.12
-
46
-
-
0026578668
-
Multiple point mutation of N-ras and K-ras oncogenes in myelodysplastic syndrome and acute myelogenous leukaemia
-
Nakagawa, T., Saitoh, S., Imoto, S., Itoh, M., Tsutsumi, M., Hikiji, K., Nakamura, H., Matozaki, S., Ogawa, R., Nakao, Y. & Fujitja, T. (1992) Multiple point mutation of N-ras and K-ras oncogenes in myelodysplastic syndrome and acute myelogenous leukaemia. Oncology, 49, 114-122.
-
(1992)
Oncology
, vol.49
, pp. 114-122
-
-
Nakagawa, T.1
Saitoh, S.2
Imoto, S.3
Itoh, M.4
Tsutsumi, M.5
Hikiji, K.6
Nakamura, H.7
Matozaki, S.8
Ogawa, R.9
Nakao, Y.10
Fujitja, T.11
-
47
-
-
0031055236
-
Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator
-
Okazaki, M., Kishida, S., Hinoi, T., Hasegawa, T., Tamada, M., Kataoka, T. & Kikuchi, A. (1997) Synergistic activation of c-fos promoter activity by Raf and Ral GDP dissociation stimulator. Oncogene, 14, 515-521.
-
(1997)
Oncogene
, vol.14
, pp. 515-521
-
-
Okazaki, M.1
Kishida, S.2
Hinoi, T.3
Hasegawa, T.4
Tamada, M.5
Kataoka, T.6
Kikuchi, A.7
-
48
-
-
0030941460
-
Ras signalling linked to the cell cycle machinery by the retinoblastoma protein
-
Peeper, D.S., Upton, T.M., Ladha, M.H., Neuman, E., et al (1997) Ras signalling linked to the cell cycle machinery by the retinoblastoma protein. Nature, 386, 177-181.
-
(1997)
Nature
, vol.386
, pp. 177-181
-
-
Peeper, D.S.1
Upton, T.M.2
Ladha, M.H.3
Neuman, E.4
-
49
-
-
0027368352
-
BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein
-
Pendergast, A.M., Quilliam, L.A., Cripe, L.D., Bassing, C.H., Dai, Z., Li, N., Batzer, A., Rabun, K.M., Der, C.J., Schlessinger, J. & Gishizky, M.L. (1993) BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein. Cell, 75, 175-185.
-
(1993)
Cell
, vol.75
, pp. 175-185
-
-
Pendergast, A.M.1
Quilliam, L.A.2
Cripe, L.D.3
Bassing, C.H.4
Dai, Z.5
Li, N.6
Batzer, A.7
Rabun, K.M.8
Der, C.J.9
Schlessinger, J.10
Gishizky, M.L.11
-
50
-
-
0028081190
-
Sequential acquisition of trisomy-9 and N-RAS mutation in acute myeloid leukaemia demonstrated by analysis of isolated leukaemic colonies
-
Price, C., Marshall, C. & Bashey, A. (1994) Sequential acquisition of trisomy-9 and N-RAS mutation in acute myeloid leukaemia demonstrated by analysis of isolated leukaemic colonies. British Journal of Haematology, 88, 338-342.
-
(1994)
British Journal of Haematology
, vol.88
, pp. 338-342
-
-
Price, C.1
Marshall, C.2
Bashey, A.3
-
52
-
-
0024990090
-
N-ras mutations in adult de novo acute myeloid leukemia: Prevalence and clinical significance
-
Radich, J., Kopecky, K.J., Willman, C.L., Weick, J., Head, D., Appelbaum, F. & Smith, C. (1990) N-ras mutations in adult de novo acute myeloid leukemia: prevalence and clinical significance. Blood, 76, 801-807.
-
(1990)
Blood
, vol.76
, pp. 801-807
-
-
Radich, J.1
Kopecky, K.J.2
Willman, C.L.3
Weick, J.4
Head, D.5
Appelbaum, F.6
Smith, C.7
-
53
-
-
0028074316
-
Phosphatidylinositol-3-OH kinase as a direct target of Ras
-
Rodriguez-Viciana, P., Warne, P.H., Dhand, R., Vanhaesebroeck, B., Gout, I., Fry, M., Waterfield, M.D. & Downward, J. (1994) Phosphatidylinositol-3-OH kinase as a direct target of Ras. Nature, 370, 527-532.
-
(1994)
Nature
, vol.370
, pp. 527-532
-
-
Rodriguez-Viciana, P.1
Warne, P.H.2
Dhand, R.3
Vanhaesebroeck, B.4
Gout, I.5
Fry, M.6
Waterfield, M.D.7
Downward, J.8
-
54
-
-
0027263326
-
Platelet-derived growth factor receptor mediates activation of Ras through different signalling pathways in different cell types
-
Satoh, Y., Fantl, W., Escobedo, J., Williams, L. & Kaziro, Y. (1993) Platelet-derived growth factor receptor mediates activation of Ras through different signalling pathways in different cell types. Molecular and Cellular Biology, 13, 3706-3713.
-
(1993)
Molecular and Cellular Biology
, vol.13
, pp. 3706-3713
-
-
Satoh, Y.1
Fantl, W.2
Escobedo, J.3
Williams, L.4
Kaziro, Y.5
-
55
-
-
0029790791
-
The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene
-
Senechal, K., Halpern, J. & Sawyers, C. (1996) The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene. Journal of Biological Chemistry, 271, 23255-23261.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 23255-23261
-
-
Senechal, K.1
Halpern, J.2
Sawyers, C.3
-
56
-
-
0023242257
-
Expression of normal and mutant ras proteins in human acute leukemia
-
Shen, M.P.V., Aldrich, T.H., Venta-Perez, G., Franza, B.R.J. & Furth, M.E. (1987) Expression of normal and mutant ras proteins in human acute leukemia. Oncogene, 1, 157-165.
-
(1987)
Oncogene
, vol.1
, pp. 157-165
-
-
Shen, M.P.V.1
Aldrich, T.H.2
Venta-Perez, G.3
Franza, B.R.J.4
Furth, M.E.5
-
57
-
-
0030947237
-
Homozygous inactivation of the NF-1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders
-
Side, L., Taylor, B., Cayouette, M., Conner, E., Thompson, P., Luce, M. & Keith, S. (1997) Homozygous inactivation of the NF-1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders. New England Journal of Medicine, 336, 1713-1720.
-
(1997)
New England Journal of Medicine
, vol.336
, pp. 1713-1720
-
-
Side, L.1
Taylor, B.2
Cayouette, M.3
Conner, E.4
Thompson, P.5
Luce, M.6
Keith, S.7
-
58
-
-
0025923864
-
Association of p21ras with phosphatidylinositol 3-kinase
-
Sjolander, A., Yamamoto, K., Huber, B.E. & Lapetina, E.G. (1991) Association of p21ras with phosphatidylinositol 3-kinase. Proceedings of the National Academy of Sciences of the United States of America, 88, 7908-7912.
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, pp. 7908-7912
-
-
Sjolander, A.1
Yamamoto, K.2
Huber, B.E.3
Lapetina, E.G.4
-
59
-
-
0028577298
-
Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap
-
Spaargaren, M. & Bischoff, J.R. (1994) Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap. Proceedings of the National Academy of Sciences of the United States of America, 91, 12609-12613.
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, pp. 12609-12613
-
-
Spaargaren, M.1
Bischoff, J.R.2
-
60
-
-
0021184853
-
Transformation of NIM-3T3-CELLS by microinjection of Ha-ras p21 protein
-
Stacey, D.W. & Kung, H.-F. (1984) Transformation of NIM-3T3-CELLS by microinjection of Ha-ras p21 protein. Nature, 310, 508-511.
-
(1984)
Nature
, vol.310
, pp. 508-511
-
-
Stacey, D.W.1
Kung, H.-F.2
-
61
-
-
0027974256
-
Neurofibromatosis and childhood leukaemia/lymphoma: A population based UKCCSG study
-
Stiller, C.A., Chessels, J. & Fitchett, M. (1994) Neurofibromatosis and childhood leukaemia/lymphoma: a population based UKCCSG study. British Journal of Cancer, 70, 969-972.
-
(1994)
British Journal of Cancer
, vol.70
, pp. 969-972
-
-
Stiller, C.A.1
Chessels, J.2
Fitchett, M.3
-
62
-
-
0029085749
-
SSCP detection of N-ras promoter mutations in AML patients
-
Thorn, J., Molloy, P. & Hand, H. (1995) SSCP detection of N-ras promoter mutations in AML patients. Experimental Hematology, 23, 1008-1103.
-
(1995)
Experimental Hematology
, vol.23
, pp. 1008-1103
-
-
Thorn, J.1
Molloy, P.2
Hand, H.3
-
63
-
-
0021967321
-
In yeast. RAS proteins are controlling elements of adenylate cyclase
-
Toda, T., Uno, I., Ishikawa, T., Powers, S., Kataoka, T., Broek, D., Cameron, S., Broach, J., Matsumoto, K. & Wigler, M. (1985) In yeast. RAS proteins are controlling elements of adenylate cyclase. Cell, 40, 27-36.
-
(1985)
Cell
, vol.40
, pp. 27-36
-
-
Toda, T.1
Uno, I.2
Ishikawa, T.3
Powers, S.4
Kataoka, T.5
Broek, D.6
Cameron, S.7
Broach, J.8
Matsumoto, K.9
Wigler, M.10
-
64
-
-
0023232478
-
Ras gene activation in a minor proportion of the blast population in acute myeloid leukemia
-
Toksoz, D., Farr, C.J. & Marshall, C.J. (1987) Ras gene activation in a minor proportion of the blast population in acute myeloid leukemia. Oncogene, 1, 409-413.
-
(1987)
Oncogene
, vol.1
, pp. 409-413
-
-
Toksoz, D.1
Farr, C.J.2
Marshall, C.J.3
-
65
-
-
0028144848
-
Apoptosis regulation by interaction of bcl-2 protein and Raf-1 kinase
-
Wang, H., Miyashita, T., Takayama, S., Sato, T., Torigoe, T., Krajewski, S., Tanaka, S., Hovey, L., Troppmair, J., Rapp, U. & Reed, J. (1994) Apoptosis regulation by interaction of bcl-2 protein and Raf-1 kinase. Oncogene, 9, 2751-2756.
-
(1994)
Oncogene
, vol.9
, pp. 2751-2756
-
-
Wang, H.1
Miyashita, T.2
Takayama, S.3
Sato, T.4
Torigoe, T.5
Krajewski, S.6
Tanaka, S.7
Hovey, L.8
Troppmair, J.9
Rapp, U.10
Reed, J.11
-
66
-
-
0345498292
-
Bcl-2 targets the protein kinase Raf-1 to mitochondria
-
Wang, H., Rapp, U. & Reed, J. (1996a) Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell, 87, 629-638.
-
(1996)
Cell
, vol.87
, pp. 629-638
-
-
Wang, H.1
Rapp, U.2
Reed, J.3
-
67
-
-
0029937303
-
Bcl-2 interacting protein BAG-1. binds to and activates the kinase Raf-1
-
Wang, H., Takayama, S., Rapp, U. & Reed, J. (1996b) Bcl-2 interacting protein BAG-1. binds to and activates the kinase Raf-1. Proceedings of the National Academy of Sciences of the United States of America, 93, 7063-7068.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, pp. 7063-7068
-
-
Wang, H.1
Takayama, S.2
Rapp, U.3
Reed, J.4
-
68
-
-
0029950722
-
A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation
-
White, M., Vale, T., Camonis, J., Schaefer, E. & Wigler, M. (1996) A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. Journal of Biological Chemistry, 271, 16439-16442.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 16439-16442
-
-
White, M.1
Vale, T.2
Camonis, J.3
Schaefer, E.4
Wigler, M.5
-
69
-
-
0025091465
-
The neurofibromatosis type 1 gene encodes a protein related to GAP
-
Xu, G., O'Connell, P., Viskochil, D., Cawthon, R., Robertson, M., Culver, M., Dunn, D., Stevens, J., Gesteland, R., White, R. & Weiss, R. (1990) The neurofibromatosis type 1 gene encodes a protein related to GAP. Cell 62, 599-608.
-
(1990)
Cell
, vol.62
, pp. 599-608
-
-
Xu, G.1
O'Connell, P.2
Viskochil, D.3
Cawthon, R.4
Robertson, M.5
Culver, M.6
Dunn, D.7
Stevens, J.8
Gesteland, R.9
White, R.10
Weiss, R.11
-
70
-
-
0027525104
-
The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1b-converting enzyme
-
Yuan, J., Shahim, S., Ledoux, S., Ellis, H., Horvitz, H. (1993) The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1b-converting enzyme. Cell, 75, 641-652.
-
(1993)
Cell
, vol.75
, pp. 641-652
-
-
Yuan, J.1
Shahim, S.2
Ledoux, S.3
Ellis, H.4
Horvitz, H.5
-
71
-
-
0028244383
-
Persistence of an activating N-RAS oncogene mutation in clonogenic progenitor cells from an acute myeloid leukaemia patient in remission
-
Zaheer, H., Bagnara, M., Gibson, F., Robinson, G., Rutherford, T. & Gordon-Smith, E.C. (1994) Persistence of an activating N-RAS oncogene mutation in clonogenic progenitor cells from an acute myeloid leukaemia patient in remission. British Journal of Haematology, 86, 298-302.
-
(1994)
British Journal of Haematology
, vol.86
, pp. 298-302
-
-
Zaheer, H.1
Bagnara, M.2
Gibson, F.3
Robinson, G.4
Rutherford, T.5
Gordon-Smith, E.C.6
-
73
-
-
0030745646
-
Apaf-1, A human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou, H., Henzel, W., Liu, X., Lutschg, A. & Wang, X. (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell, 90, 405-413.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.2
Liu, X.3
Lutschg, A.4
Wang, X.5
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