Transport kinetics of iron chelators and their chelates in Caco-2 cells

Pharmaceutical Research

Volumn 23, Issue 2, 2006, Pages 280-290

  Huang, Xi Ping ^a   Spino, M ^a,b   Thiessen, J J ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ApoPharma Inc   (Canada)

Author keywords

Caco 2 cells; Iron chelate; Iron chelator; Iron overload

Indexed keywords

CHELATE; CP 363; CP 502; DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; IRON CHELATING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG SCREENING; DRUG TRANSPORT; HUMAN; HUMAN CELL; IN VIVO STUDY; INTESTINE ABSORPTION; PH; PRIORITY JOURNAL; TEMPERATURE; TRANSPORT KINETICS;

ALGORITHMS; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT, ACTIVE; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTRIC IMPEDANCE; FLUORESCEIN; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; IRON; IRON CHELATING AGENTS; KINETICS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 32544446910     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-005-9258-5     Document Type: Article

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