The role of parathyroid hormone-related protein in the regulation of osteoclastogenesis by cementoblasts

Journal of Periodontology

Volumn 75, Issue 9, 2004, Pages 1247-1254

  Boabaid, Fernanda ^a,b   Berry, Janice E ^a   Koh, Amy J ^a   Somerman, Martha J ^c   McCauley, Laurie K ^a,d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cementoblasts; Ligand, NF kappa B; Osteoblasts; Osteoclasts; Osteoprotegerin; Proteins, parathyroid hormone related; Receptor activator, NF kappa B; Tooth eruption; Tooth root

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PARATHYROID HORMONE RELATED PROTEIN; PARATHYROID HORMONE[1-34]; RECEPTOR;

ANIMAL CELL; ARTICLE; BONE CELL; BONE MARROW CELL; CELL ACTIVITY; CELL COUNT; CELL IMMORTALIZATION; CELL LYSATE; CEMENTOBLAST; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VIVO STUDY; NONHUMAN; OSTEOCLAST; PROTEIN EXPRESSION; TOOTH DEVELOPMENT; TOOTH DISEASE; TOOTH ERUPTION;

ACID PHOSPHATASE; ALVEOLAR PROCESS; ANIMALS; CARRIER PROTEINS; CELL COUNT; CELLS, CULTURED; COCULTURE TECHNIQUES; DENTAL CEMENTUM; GLYCOPROTEINS; ISOENZYMES; LIGANDS; MEMBRANE GLYCOPROTEINS; MICE; MYELOID CELLS; NF-KAPPA B; OSTEOCLASTS; OSTEOPROTEGERIN; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE FRAGMENTS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR; TERIPARATIDE; TOOTH GERM; TUMOR NECROSIS FACTOR-ALPHA;

EID: 7044272874     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2004.75.9.1247     Document Type: Article

References (37)

1. Wise GE, Frazier-Bowers S, D'Souza RN. Cellular, molecular and genetic determinants of tooth eruption. Crit Rev Oral Biol Med 2002;13:323-334.
2. Philbrick WM, Wysolmerski JJ, Galbraith S, et al. Defining the roles of parathyroid hormone-related protein in normal physiology. Physiol Rev 1996;76:127-173.
3. Fiaschi-Taesch NM, Stewart AF. Minireview: Parathyroid hormone-related protein as an intracrine factor - trafficking mechanisms and functional consequences. Endocrinology 2003;144:407-411.
4. Philbrick WM, Dreyer BE, Nakchbandi IA, Karaplis AC. Parathyroid hormone-related protein is required for tooth eruption. Proc Natl Acad Sci (USA) 1998;95:11846-11851.
5. Wise GE, Lumpkin SJ, Huang H, Zhang Q. Osteoprotegerin and osteoclast differentiation factor in tooth eruption. J Dent Res 2000;79:1937-1942.
6. Kitahara Y, Suda N, Kuroda T, Beck F, Hammond VE, Takano Y. Disturbed tooth development in parathyroid hormone-related protein (PTHrP)-gene knockout mice. Bone 2002;30:48-56.
7. Wysolmerski JJ, Cormier S, Philbrick WM, et al. Absence of functional type 1 parathyroid hormone (PTH)/PTH-related protein receptors in humans is associated with abnormal breast development and tooth impaction. J Clin Endocrinol Metab 2001;86:1788-1794.
8. Schipani E, Lanske B, Hunzelman J, et al. Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide. Proc Natl Acad Sci (USA) 1997;94:13689-13694.
9. Beck F, Tucci J, Russell A, Senior PV, Ferguson MW. The expression of the gene coding for parathyroid hormone-related protein (PTHrP) during tooth development in the rat. Cell Tissue Res 1995;280:283-290.
10. Tenorio D, Hughes FJ. An immunohistochemical investigation of the expression of parathyroid hormone receptors in rat cementoblasts. Arch Oral Biol 1996;41: 299-305.
11. Ouyang H, McCauley LK, Berry JE, D'Errico JA, Strayhorn CL, Somerman MJ. Response of immortalized murine cementoblasts/periodontal ligament cells to parathyroid hormone and parathyroid hormone-related protein in vitro. Arch Oral Biol 2000;45:293-303.
12. Suda T, Takahashi N, Udagawa N, Jimi E, Gillespie MT, Martin TJ. Modulation of osteoclast differentiation and function by new members of tumor necrosis factor receptor and ligand families. Endocr Rev 1999;20:345-357.
13. Wise GE, Huang H, Zhang Q, Yao S. Effects of injections of PTHrP on tooth eruption and osteoprotegerin gene expression. Int J Oral Biol 2001;26:81-86.
14. Mekaapiruk K, Suda N, Hammond VE, et al. The influence of parathyroid hormone-related protein PTHrP on tooth germ development and osteoclastogenesis in alveolar bone of PTHrP-knock out and wild-type mice in vitro. Arch Oral Biol 2002;47:665-672.
15. McCauley LK, Nohutcu RM. Mediators of periodontal osseous destruction and remodeling: Principles and implications for diagnosis and therapy. J Periodontol 2002;73: 1377-1391.
16. Kostenuik P, Shalhoub V. Osteoprotegerin: A physiological and pharmacological inhibitor of bone resorption. Curr Pharm Des 2001;7:613-635.
17. Khosla S. Minireview: The OPG/RANKL/RANK system. Endocrinology 2001;142:5050-5055.
18. Karsenty G, Wagner EF. Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2002;2: 389-406.
19. Lee SK, Lorenzo JA. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation. Endocrinology 1999;140:3553-3561.
20. Faucheux C, Horton MA, Price JS. Nuclear localization of type I parathryoid hormone/parathyroid hormone-related protein receptors in deer antler osteoclasts: Evidence for parathyroid hormone related protein and receptor activator of NFκB-dependent effects on osteoclast formation in regenerating mammalian bone. J Bone Miner Res 2002; 17: 455-464.
21. Theill LE, Boyle WJ, Penninger JM. RANK-L and RANK: T cells, bone loss, and mammalian evolution. Annu Rev Immunol 2002;20:795-823.
22. Hasegawa T, Yoshimura Y, Kikuiri T, et al. Expression of receptor activator of NFκB ligand and osteoprotegerin in culture of human periodontal ligament cells. J Periodontal Res 2002;37:405-411.
23. Rani CCS, Macdougall M. Dental cells express factors that regulate bone resorption. Mol Cell Biol Res Commun 2000;3:145-152.
24. D'Errico JA, Berry JE, Ouyang H, Strayhorn CL, Windle JJ, Somerman MJ. Employing a transgenic animal model to obtain cementoblasts in vitro. J Periodontol 2000;71: 63-72.
25. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
26. Nakchbandi IA, Weir EE, Insogna KL, Philbrick WM, Broadus AE. Parathyroid hormone related protein induces spontaneous osteoclast formation via a paracrine cascade. Proc Natl Acad Sci (USA) 2000;97:7296-7300.
27. Shiotani A, Takami M, Itoh K, Shibasaki Y, Sasaki Y. Regulation of osteoclast differentiation and function by receptor activator of NFκB ligand and osteoprotegerin. Anat Rec 2002;268:137-146.
28. Wada N, Maeda H, Tanabe K, et al. Periodontal ligament cells secrete the factor that inhibits osteoclastic differentiation and function: The factor is osteoprotogerin/osteoclastogenesis inhibitory factor. J Periodontal Res 2001;36: 56-63.
29. Oshiro T, Shiotani A, Shibasaki Y, Sasaki T. Osteoclasts induction in periodontal tissue during experimental movement of incisors in osteoprotegerin-deficient mice. Anat Rec 2002;266:218-225.
30. Kartsogiannis V, Zhou H, Horwood NJ, et al. Localization of RANKL (receptor activator of NFκB ligand) mRNA and protein in skeletal and extraskeletal tissues. Bone 1999;25: 525-534.
31. Shiotani A, Shibasaki Y, Sasaki T. Localization of receptor activator of NFκB ligand, RANKL, in periodontal tissues during experimental movement of rat molars. J Electron Microsc 2001;50:365-369.
32. Fuller K, Wong B, Fox S, Choi Y, Chambers TJ. TRANCE is necessary and sufficient for osteoclast-mediated activation of bone resorption in osteoclasts. J Exp Med 1998; 188:997-1001.
33. Itoh K, Udagawa N, Matsuzaki K, et al. Importance of membrane or matrix-associated forms of MCSF and RANKL/ ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors. J Bone Miner Res 2000;15:1766-1775.
34. Fuller K, Owens JM, Chambers TJ. Induction of osteoclast formation by parathyroid hormone depends on an action on stromal cells. Endocrinology 1998;158:341-350.
35. Jimi E, Akiyama S, Tsurukai T, et al. Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. J Immunol 1999; 163:434-442.
36. Kim N, Takami M, Rho J, Josien R, Choi Y. A novel member of the leukocyte receptor complex regulates osteoclast differentiation. J Exp Med 2002;195:201-209.
37. So H, Rho J, Jeong D, et al. Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte 24 receptor osteoclast-associated receptor gene expression. J Biol Chem 2003;278:24209-24216.