Identification of cytochrome P-450s involved in the formation of APNH from norharman with aniline

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 562, Issue 1-2, 2004, Pages 19-25

  Nishigaki, Rena ^a   Totsuka, Yukari ^a   Takamura Enya, Takeji ^a   Sugimura, Takashi ^a   Wakabayashi, Keiji ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

2 amino 3,8 dimethylimidazo 4,5 f quinoxaline; aminophenylnorharman 9 (4 aminophenyl) 9H pyrido 3,4 b indole ; APNH; CYP; cytochrome P 450; HCAs; heterocyclic amines; MeIQx; Norharman; PHA; phenylhydroxylamine; thiotepa; triethylenethiophosphoramide

Indexed keywords

AMINOPHENYLNORHARMAN; ANILINE; BETA CARBOLINE; BETA CARBOLINE DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A4; FURAFYLLINE; KETOCONAZOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; HUMAN; INCUBATION TIME; INHIBITION KINETICS; LIVER; MALE; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT;

ANILINE COMPOUNDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; HARMINE; INDOLES; MUTAGENS; PYRIDINES; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 3242789501     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2004.05.003     Document Type: Article

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