A TRPV2-PKA signaling module for transduction of physical stimuli in mast cells

Journal of Experimental Medicine

Volumn 200, Issue 2, 2004, Pages 137-147

  Stokes, Alexander J ^a   Shimoda, Lori M N ^a   Koblan Huberson, Murielle ^a   Adra, Chaker N ^b   Turner, Helen ^a,c,d  

^a QUEEN S MEDICAL CENTER   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c UNIVERSITY OF HAWAII   (United States)

^d University Tower 8   (United States)

Author keywords

Calcium channels; Inflammation; Physical urticaria; Transient receptor potential; Vanilloid receptor

Indexed keywords

ACYL COENZYME A; CALCIUM CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN SUBUNIT; TRANSIENT RECEPTOR POTENTIAL CHANNEL; UNCLASSIFIED DRUG; VANILLOID RECEPTOR; VANILLOID RECEPTOR 2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IN VITRO STUDY; MAST CELL; MECHANICAL STIMULATION; NONHUMAN; OLIGOMERIZATION; OSMOTIC STRESS; PRESSURE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; THERMAL STIMULATION; URTICARIA;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CALCIUM; CALCIUM CHANNELS; CATIONS; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA, COMPLEMENTARY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MAST CELLS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEROTONIN; SIGNAL TRANSDUCTION; TEMPERATURE; TIME FACTORS; TRPV CATION CHANNELS;

EID: 3242784060     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20032082     Document Type: Article

References (51)

1. Church, M.K., Y. Okayama, and S. el-Lati. 1991. Mediator secretion from human skin mast cells provoked by immunological and non-immunological stimulation. Skin Pharmacol. 4:15-24.
2. Galli, S.J. 2000. Mast cells and basophils. Curr. Opin. Hematol. 7:32-39.
3. Noli, C., and A. Miolo. 2001. The mast cell in wound healing. Vet. Dermatol. 12:303-313.
4. Metcalfe, D.D., D. Baram, and Y.A. Mekori. 1997. Mast cells. Physiol. Rev. 77:1033-1079.
5. Sharma, B.B., J.R. Apgar, and F.T. Liu. 2002. Mast cells. Receptors, secretagogues, and signaling. Clin. Rev. Allergy Immunol. 22:119-148.
6. Eggleston, P.A., A. Kagey-Sobotka, and L.M. Lichtenstein, 1987. A comparison of the osmotic activation of basophils and human lung mast cells. Am. Rev. Respir. Dis. 135:1043-1048.
7. Fredholm, B., and O. Hagermark. 1970. Studies on histamine release from skin and from peritoneal mast cells of the rat induced by heat. Acta Derm. Venereol. 50:273-277.
8. Silber, G., D. Proud, J. Warner, R. Naclerio, A. Kagey-Sobotka, L. Lichtenstein, and P. Eggleston. 1988. In vivo release of inflammatory mediators by hyperosmolar solutions. Am. Rev. Respir. Dis. 137:606-612.
9. Grabbe, J. 2001. Pathomechanisms in physical urticaria. J. Investig. Dermatol. Symp. Proc. 6:135-136.
10. Soter, N.A., and F. Austen. 1977. Urticaria, angioedema, and mediator release in humans in response to physical environmental stimuli. Fed. Proc. 36:1736-1741.
11. Soter, N.A., and S.I. Wasserman. 1980. Physical urticaria/angioedema: an experimental model of mast cell activation in humans. J. Allergy Clin. Immunol. 66:358-365.
12. Claudy, A. 2001. Cold urticaria. J. Investig. Dermatol. Symp. Proc. 6:141-142.
13. Daman, L., P. Lieberman, M. Ganier, and K. Hashimoto. 1978. Localized heat urticaria. J. Allergy Clin. Immunol. 61:273-278.
14. Greaves, M.W. 1991. The physical urticarias. Clin. Exp. Allergy. 21:284-289.
15. Merk, H.F. 2001. Standard treatment: the role of antihistamines. J. Investig. Dermatol. Symp. Proc. 6:153-156.
16. Greaves, M.W. 2003. Chronic idiopathic urticaria. Curr. Opin. Allergy Clin. Immunol. 3:363-368.
17. Benham, C.D., M.J. Gunthorpe, and J.B. Davis. 2003. TKPV channels as temperature sensors. Cell Calcium. 33:479-487.
18. Caterina, M.J., M.A. Schumacher, M. Tominaga, T.A. Rosen, J.D. Levine, and D. Julius. 1997. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature. 389:816-824.
19. Julius, D., and A.I. Basbaum. 2001. Molecular mechanisms of nociception. Nature. 413:203-210.
20. Nilius, B. 2003. From TRPs to SOCs, CCEs and CRACs: consensus and contraversies. Cell Calcium. 33:293-298.
21. Caterina, M.J., T.A. Rosen, M. Tominaga, A.J. Brake, and D. Julius. 1999. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature. 398:436-441.
22. Peier, A.M., A.J. Reeve, D.A. Andersson, A. Moqrich, T.J. Earley, A.C. Hergarden, G.M. Story, S. Colley, J.B. Hogenesch, P. McIntyre, et al. 2002. A heat-sensitive TRP channel expressed in keratinocytes. Science. 296:2046-2049.
23. Smith, G.D., M.J. Gunthorpe, R.E. Kelsell, P.D. Hayes, P. Reilly, P. Facer, J.E. Wright, J.C. Jerman, J.P. Walhin, L. Ooi, et al. 2002. TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature. 418:186-190.
24. Xu, H., I.S. Ramsey, S.A. Kotecha, M.M. Moran, J.A. Chong, D. Lawson, P. Ge, J. Lilly, I. Silos-Santiago, Y. Xie, et al. 2002. TRPV3 is a calcium-permeable temperature-sensitive cation channel. Nature. 418:181-186.
25. Guler, A.D., H. Lee, T. Iida, I. Shimizu, M. Tominaga, and M. Caterina. 2002. Heat-evoked activation of the ion channel, TRPV4. J. Neurosci. 22:6408-6414.
26. Watanabe, H., J. Vriens, S.H. Suh, C.D. Benham, G. Droogmans, and B. Nilius. 2002. Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells. J. Biol. Chem. 277:47044-47051.
27. Alessandri-Haber, N., J.J. Yeh, A.E. Boyd, C.A. Parada, X. Chen, D.B. Reichling, and J.D. Levine. 2003. Hypotonicity induces TRPV4-mediated nociception in rat. Neuron. 39:497-511.
28. Boels, K., G. Glassmeier, D. Herrmann, I.B. Riedel, W. Hampe, I. Kojima, J.R. Schwarz, and H.C. Schaller. 2001. The neuropeptide head activator induces activation and translocation of the growth-factor-regulated Ca(2+)-permeable channel GRC. J. Cell Sci. 114:3599-3606.
29. Iwata, Y., Y. Katanosaka, Y. Arai, K. Komamura, K. Miyatake, and M. Shigekawa. 2003. A novel mechanism of myocyte degeneration involving the Ca2+-permeable growth factor-regulated channel. J. Cell Biol. 161:957-967.
30. Kanzaki, M., Y.Q. Zhang, H. Mashima, L. Li, H. Shibata, and I. Kojima. 1999. Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nat. Cell Biol. 1:165-170.
31. Trevisani, M., D. Smart, M.J. Gunthorpe, M. Tognetto, M. Barbieri, B. Campi, S. Amadesi, J. Gray, J.C. Jerman, S.J. Brough, et al. 2002. Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat. Neurosci. 5:546-551.
32. De Petrocellis, L., S. Harrison, T. Bisogno, M. Tognetto, I. Brandi, G.D. Smith, C. Creminon, J.B. Davis, P. Geppetti, and V. Di Marzo. 2001. The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase. J. Neurochem. 77:1660-1663.
33. Rathee, P.K., C. Distler, O. Obreja, W. Neuhuber, G.K. Wang, S.Y. Wang, C. Nau, and M. Kress. 2002. PKA/AKAP/VR-1 module: a common link of Gs-mediated signaling to thermal hyperalgesia. J. Neurosci. 22:4740-4745.
34. Li, H., B. Degenhardt, D. Tobin, Z.X. Yao, K. Tasken, and V. Papadopoulos. 2001. Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein. Mol. Endocrinol. 15:2211-2228.
35. Vijayaraghavan, S., S.A. Goueli, M.P. Davey, and D.W. Carr. 1997. Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility. J. Biol. Chem. 272:4747-4752.
36. Schagger, H., W.A. Cramer, and G. von Jagow. 1994. Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis. Anal. Biochem. 217:220-230.
37. Schamel, W.W., and M. Reth. 2000. Monomeric and oligomeric complexes of the B cell antigen receptor. Immunity. 13:5-14.
38. Turner, H., A. Fleig, A. Stokes, J.P. Kinet, and R. Penner. 2003. Discrimination of intracellular calcium store subcompartments using TRPV1 (transient receptor potential channel, vanilloid subfamily member 1) release channel activity. Biochem. J. 371:341-350.
39. Nadler, M.J., M.C. Hermosura, K. Inabe, A.L. Perraud, Q. Zhu, A.J. Stokes, T. Kurosaki, J.P. Kinet, R. Penner, A.M. Scharenberg, and A. Fleig. 2001. LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability. Nature. 411:590-595.
40. Heiner, I., J. Eisfeld, and A. Luckhoff. 2003. Role and regulation of TRP channels in neutrophil granulocytes. Cell Calcium 33:533-540.
41. Minke, B., and B. Cook. 2002. TRP channel proteins and signal transduction. Physiol. Rev. 82:429-472.
42. Rosenbaum, T., M. Awaya, and S.E. Gordon. 2002. Subunit modification and association in VR1 ion channels. BMC Neurosci. 3:4.
43. van de Graaf, S.F., J.G. Hoenderop, D. Gkika, D. Lamers, J. Prenen, U. Rescher, V. Gerke, O. Staub, B. Nilius, and R.J. Bindels. 2003. Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex. EMBO J. 22:1478-1487.
44. Kedei, N., T. Szabo, J.D. Lile, J.J. Treanor, Z. Olah, M.J. Iadarola, and P.M. Blumberg. 2001. Analysis of the native quaternary structure of vanilloid receptor 1. J. Biol. Chem. 276:28613-28619.
45. Cesare, P., A. Moriondo, V. Vellani, and P.A. McNaughton. 1999. Ion channels gated by heat. Proc. Natl. Acad. Sci. USA. 96:7658-7663.
46. Clapham, D.E., C. Montell, G. Schultz, and D. Julius. 2003. International union of pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels. Pharmacol. Rev. 55:591-596.
47. Maingret, F., I. Lauritzen, A.J. Patel, C. Heurteaux, R. Reyes, F. Lesage, M. Lazdunski, and E. Honore. 2000. TREK-1 is a heat-activated background K(+) channel. EMBO J. 19:2483-2491.
48. Colledge, M., and J.D. Scott. 1999. AKAPs: from structure to function. Trends Cell Biol. 9:216-221.
49. Liu, J., H. Li, and V. Papadopoulos. 2003. PAP7, a PBR/PKA-RIalpha- associated protein: a new element in the relay of the hormonal induction of steroidogenesis. J. Steroid Biochem. Mol. Biol. 85:275-283.
50. Biro, T., M. Maurer, S. Modarres, N.E. Lewin, C. Brodie, G. Acs, P. Acs, R. Paus, and P.M. Blumberg. 1998. Characterization of functional vanilloid receptors expressed by mast cells. Blood. 91:1332-1340.
51. Lewin, G.R., A. Rueff, and L.M. Mendell. 1994. Peripheral and central mechanisms of NGF-induced hyperalgesia. Eur. J. Neurosci. 6:1903-1912.