The second generation of COX-2 inhibitors: Clinical pharmacological point of view

Mini-Reviews in Medicinal Chemistry

Volumn 4, Issue 6, 2004, Pages 617-624

  Stichtenoth, Dirk O ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Efficacy; Etoricoxib; Inflammation; Lumiracoxib; Pain; Parecoxib; Safety; Valdecoxib

Indexed keywords

ACETYLSALICYLIC ACID; CS 502; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; DIGOXIN; ETORICOXIB; FENTANYL; GLIBENCLAMIDE; GLUCOCORTICOID; IBUPROFEN; KETOROLAC; LUMIRACOXIB; METHOTREXATE; MIDAZOLAM; MORPHINE; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; ORAL CONTRACEPTIVE AGENT; OXYCODONE; PARACETAMOL; PARECOXIB; PREDNISOLONE; PROPOFOL; RIFAMPICIN; TRAMADOL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALDECOXIB; WARFARIN;

ANALGESIC NEPHROPATHY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL TRIAL; COLON DISEASE; COLON ULCER; DIGESTIVE SYSTEM INJURY; DIGESTIVE SYSTEM PERFORATION; DISEASE EXACERBATION; DRUG ABSORPTION; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFICACY; DRUG EXCRETION; DRUG HALF LIFE; DRUG HYPERSENSITIVITY; DRUG METABOLISM; DRUG SAFETY; DRUG SELECTIVITY; DRUG SOLUBILITY; DYSMENORRHEA; DYSPEPSIA; GASTRODUODENAL ULCER; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL SYMPTOM; GASTROINTESTINAL TOXICITY; GLOMERULUS FILTRATION RATE; HEART ARREST; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; HYPERKALEMIA; HYPERTENSION; INFLAMMATION; INTESTINE OBSTRUCTION; INTESTINE ULCER; KIDNEY BLOOD FLOW; KIDNEY DISEASE; KNEE OSTEOARTHRITIS; LOW BACK PAIN; LUNG TOXICITY; NONHUMAN; PAIN; PERIPHERAL EDEMA; PERIPHERAL ISCHEMIA; POSTOPERATIVE PAIN; RHEUMATOID ARTHRITIS; SHORT SURVEY; SMALL INTESTINE DISEASE; SODIUM RETENTION; STROKE; THROMBOCYTE DYSFUNCTION; THROMBOGENESIS; TOOTH PAIN; TOXIC EPIDERMAL NECROLYSIS; TRANSIENT ISCHEMIC ATTACK; VEIN THROMBOSIS; WATER RETENTION;

EID: 3242720430     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557043403783     Document Type: Short Survey

References (68)

1. Hawkey, C.J. Lancet, 1999, 353, 307.
2. Frölich, J.C. Trends Pharmacol. Sci., 1997, 18, 30.
3. Cieslik, K.; Zhu, Y.; Wu, K.K. J. Biol. Chem., 2002, 277, 49304.
4. Fitzgerald, G.A.; Patrono, C. N. Engl. J. Med, 2001, 345, 433.
5. Szczeklik, A.; Stevenson, D.D. J. Allergy Clin. Immunol., 2003, 111, 913.
6. Stichtenoth, D.O.; Frölich, J.C. Curr. Pharm. Des., 2000, 6, 1737.
7. Chavez, M.L.; DeKorte, C.J. Clin. Ther., 2003, 25, 817.
8. Cheer, S.M.; Goa, K.L. Drugs, 2001, 61, 1133.
9. Cochrane, D.J.; Jarvis, B.; Keating, G.M. Drugs, 2002, 62, 2637.
10. Ding, C.; Jones, G. Idrugs, 2002, 5, 1168.
11. Stichtenoth, D.O.; Frölich, J.C. Drugs, 2003, 63, 33.
12. Warner, T.D.; Pairet, M.; Van Ryn, J. In Therapeutic roles of selective COX-2 inhibitors; Vane, J.R.; Butting, R.M., Eds. William Harvey Press: London, 2001; pp. 76-94.
13. Riendeau, D.; Percival, M.D.; Brideau, C.; et al. J. Pharmacol. Exp. Ther., 2001, 296, 558.
14. Marshall, P.J.; Berry, C.; Wasvary, J. Ann. Rheum. Dis., 2002, 61 (Suppl. 1), 259.
15. Talley, J.HJ.; Brown, D.L.; Carter, J.S.; et al. J. Med. Chem., 2000, 43, 775.
16. Talley, J.J.; Bertenshaw, S.R.; Brown, D.L.; et al. J. Med. Chem., 2000, 43, 1661.
17. Leese, P.T.; Recker, D.P.; Kent, J.D. J. Clin. Pharmacol., 2003, 43, 504.
18. Leese, P.T.; Talwalker, S.; Kent, J.D.; Recker, D.P. Am. J. Emerg. Med., 2002, 20, 275.
19. Noveck, R.J.; Laurent, A.; Kuss, M.; Talwalker, S.; Hubbard, R.C. Clin. Drug Invest., 2001, 21, 465.
20. Wagner, J.A.; Kraft, W.; Burke, J.; et al. Arthritis Rheum., 2001, 44 (Suppl. 9), S135.
21. Rordorf, C.; Scott, G.; Milosavljev, S.; Blood, P.; Branson, J.; Greig, G. Ann. Rheum. Dis., 2002. 61 (Suppl. 1), 420.
22. Ormrod, D.; Wellington, K.; Wagstaff, A.J. Drugs, 2002, 62, 2059.
23. Agrawal, N.G.; Porras. A.G.; Matthews, C.Z.; et al. J. Clin. Pharmacol., 2003, 43, 268.
24. Scott, G.; Rordorf, C.; Blood, P.; Branson, J.; Milosavljev, S.; Greig, G. Ann. Rheum. Dis., 2002, 61 (Suppl. 1), 244.
25. Hubbard, R.; Kuss, M.; Talwalker, S.; et al. Ann. Emerg. Med., 2000, 36, S69.
26. Kassahun, K.; McIntosh, I.S.; Shou, M.; et al. Drug Metab. Dispos., 2001, 29, 813.
27. Camu, F.; Beecher, T.; Recker, D.P.; Verburg, K.M. Am. J. Ther., 2002, 9, 43.
28. Fricke, J.; Varkalis, J.; Zwillich, S.; et al. Am. J. Ther., 2002, 9, 89,
29. Desjardins, P.J.; Shu, V.S.; Recker, D.P.; Verburg, K.M.; Woolf, C.J. Anesthesiology, 2002, 97, 565.
30. Daniels, S.E.; Desjardins, P.J.; Talwalker, S.; Recker, D.P.; Verburg, K. M. J. Am. Dent. Assoc., 2002, 133, 611.
31. Torri, S.; Kuss, M.E.; Talwalker, S.C.; Daniels, S.; Snabes, M.C. Fertil. Steril., 2001, 76, S95.
32. Daniels, S.E.; Talwalker, S.; Torri, S.; Snabes, M.C.; Recker, D.P.; Verburg, K.M. Obstet. Gynecol., 2002, 100, 350.
33. Barton, S.F.; Langeland, F.F.; Snabes, M.C.; LeComte, D.; Kuss, M.E.; Dhadda, S.S.; Hubbard, R.C. Anesthesiology, 2002, 97, 306.
34. Kenaan, C.A.; Bikhazi, G.B.; Deepika, K.; Calfa, C.I.; Ortiz, K. Anesth. Analg., 2001, 92 (Suppl.), S257.
35. Rasmussen, G.L.; Steckner, K.; Hogue, C.; Torri, S.; Hubbard, R.C. Am. J. Orthop., 2002, 31, 336.
36. Malmstrom, K.; Kotey, P.; Cichanowitz, N.; Daniels, S.; Desjardins, P.J. Gynecol. Obstet. Invest., 2003, Aug 04, Epub.
37. Bellamy, N.; Buchanan, W.W.; Goldsmith, C.H.; Campbell, J.; Stitt, L.W. J. Rheumatol., 1988, 15, 1833.
38. Kivitz, A.; Eisen, G.; Zhao, W.W.; Bevirt, T.; Recker, D.P. J. Fam. Pract., 2002, 51, 530.
39. Makarowski, W.; Zhao, W.W.; Bevirt, T.; Recker, D.P. Osteoarthritis Cartilage, 2002, 10, 290.
40. Gottesdiener, K.; Schnitzer, T.; Fisher, C.; et al. Rheumatology, 2002, 41, 1052.
41. Moore, A.; Della Casa Alberghi, O.; Gitton, X.; Sloan, V.; Limona, A. Ann. Rheum. Dis., 2002, 61 (Suppl. 1), 137.
42. Bensen, W.; Weaver, A.; Espinoza, L.; Zhao, W.W.; Riley, W.; Paperiello, B.; Recker, D.P. Rheumatology, 2002, 41, 1008.
43. Curtis, S.P.; Maldonado-Cocco, J.; Losada, B.R.; Gallagher, A.E.; Ng, J.; Mukhopadhyay, S. Ann. Rheum. Dis., 2001, 60 (Suppl. 1), FR10030.
44. Matsumoto, A.K.; Melina, A.; Mandel, D.R.; et al. J. Rheumatol., 2002, 29, 1623.
45. Collantes, E.; Curtis, S.P.; Lee, K.W.; et al. BMC Fam. Pract., 2002, 3, 10.
46. Product information Bextra®. Pharmacia Europe EEIG, High Wycombe, Great Britain, March, 2003.
47. Product information Dynastat®. Pharmacia Europe EEIG, High Wycombe, Great Britain, March, 2003.
48. Sikes, D.H.; Agrawal, N.M.; Zhao, W.W.; Kent, J.D.; Recker, D.P.; Verburg, K.M. Eur. J. Gastroenterol. Hepatol., 2002, 14, 1101.
49. Agrawal, N.; Paperiello, B.; Zhao, W.W.; et al. Arthritis Rheum., 2001, 44 (Suppl.), Abstract 1917.
50. Stoltz, R.R.; Harris, S.I.; Kuss, M.E.; et al. Am. J. Gastroenterol., 2002, 97, 65.
51. Hunt, R.H.; Harper, S.; Callegari, P.; et al. Aliment. Pharmacol. Ther., 2003, 17, 201.
52. Hunt, R.H.; Harper, S.; Watson, D.J.; et al. Am. J. Gastroenterol., 2003, 98, 1725.
53. Hawkey, C.J.; Karateev, D.; Codreanu, C.; et al. Ann. Rheum. Dis., 2002, 61, (Suppl. 1), 126.
54. Product Information Bextra®. Searle, Pharmacia Corporation, Chicago, IL, October, 2003.
55. FDA-Review NDA 21-341. www.fda.gov/cder/foi/nda/2001/21-341_Bextra.htm. May 30, 2002.
56. Goldstein, J.L.; Stenson, W.; Agrawal, N.; et al. EULAR, Lissabon, 2003, AB 0113.
57. Singh, G.; Ramey, D.R.; Morfeld, D.; Shi, H.; Hatoum, H.T.; Fries, J.F. Arch. Intern. Med., 1996, 156, 1530.
58. Schnitzer, T.; Geusens, P.; Hasler, P.; et al Arthritis Rheum., 2000, 43 (Suppl.), S336.
59. Allison, M.C. Howatson, A.G.; Torrance, C.J.; Lee, F.D.; Russell, R.I. N. Engl. J. Med., 1992, 327, 749.
60. Myllykangas-Luosujärvi, R.; Aho, K.; Isomäki, H. J. Rheumatol., 1995, 22, 2214.
61. Atherton, C.T.; Jones, J.I.W.; McKaig, B.C.; et al. Ann. Rheum. Dis., 2002, 61 (Suppl. 1), 245.
62. McAdam, B.F.; Catella-Lawson, F.; Mardini, I.A.; Kapoor, S.; Lawson, J.A.; FitzGerald, G.A. Proc. Natl. Acad. Sci. USA, 1999, 96, 272.
63. Catella-Lawson, F.; McAdam, B.; Morrison, B.W.; et al. J. Pharmacol. Exp. Ther., 1999, 289, 735.
64. Dilger, K.; Herrlinger, C.; Peters, J.; Seyberth, H.W.; Schweer, H.; Klotz, U. J. Clin. Pharmacol., 2002, 42, 985.
65. Catella-Lawson, F.; Reilly, M.P.; Kapoor, S.C.; et al. N. Engl. J. Med., 2001, 345, 1809.
66. Baigent, C.; Patrono, C. Arthritis Rheum., 2003, 48, 12.
67. MacDonald, T.M.; Wei, L. Lancet, 2003, 36, 573.
68. Ouellet, M.; Riendeau, D.; Percival, M.D. Proc. Natl. Acad. Sci. USA, 2001, 98, 14583.