Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway

Molecular and Cellular Biology

Volumn 24, Issue 15, 2004, Pages 6569-6580

  Yaguchi, Hiroko ^a   Ohkura, Naganari ^a   Takahashi, Maho ^a   Nagamura, Yuko ^a   Kitabayashi, Issay ^a   Tsukada, Toshihiko ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; GENE PRODUCT; HEAT SHOCK PROTEIN 70; METHIONINE; MUTANT PROTEIN; PROTEASOME; PROTEIN; PROTEIN CHIP; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FAMILIAL CANCER; GENE INACTIVATION; HUMAN; HUMAN CELL; MEN1 GENE; MISSENSE MUTATION; MOUSE; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TUMOR SUPPRESSOR GENE; UBIQUITINATION; WILD TYPE;

AMINO ACIDS; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CHROMATIN; COS CELLS; CYSTEINE ENDOPEPTIDASES; GENES, TUMOR SUPPRESSOR; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MASS SPECTROMETRY; MICE; MICROSCOPY, FLUORESCENCE; MULTIENZYME COMPLEXES; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; MUTATION; MUTATION, MISSENSE; PEPTIDES; PLASMIDS; POLYMORPHISM, GENETIC; PRECIPITIN TESTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS; RNA; TIME FACTORS; TRANSFECTION; UBIQUITIN;

ANIMALIA;

EID: 3242699561     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.15.6569-6580.2004     Document Type: Article

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