Mechanisms of lysophosphatidic acid production

Seminars in Cell and Developmental Biology

Volumn 15, Issue 5, 2004, Pages 477-489

  Aoki, Junken ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Autotaxin; LPA receptor; Phospholipase A1; Phospholipase A2

Indexed keywords

BACTERIAL PROTEIN; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHOLIPASE; LYSOPHOSPHOLIPASE D; PHOSPHATIDIC ACID; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPASE; PHOSPHOLIPASE A1; PHOSPHOLIPASE A2; PHOSPHOLIPASE D; SPIDER VENOM; UNCLASSIFIED DRUG;

BODY FLUID; CANCER CELL; CELL DIFFERENTIATION; CELL MEMBRANE; CELL MOTILITY; CELL PROLIFERATION; CELL STIMULATION; CELL TYPE; DNA MODIFICATION; ENZYME ACTIVITY; HUMAN; LIPOGENESIS; MOLECULAR MECHANICS; NONHUMAN; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REVIEW; THROMBOCYTE;

ANIMALIA;

EID: 3242699423     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcdb.2004.05.001     Document Type: Article

References (103)

1. Tokumura A. A family of phospholipid autacoids: occurrence. Prog. Lipid Res. 34:1995;151-184
2. Moolenaar W.H. Bioactive lysophospholipids and their G protein-coupled receptors. Exp. Cell Res. 253:1999;230-238
3. Tigyi G., Parrill A.L. Molecular mechanisms of lysophosphatidic acid action. Prog. Lipid Res. 42:2003;498-526
4. Yoshida K., Nishida W., Hayashi K., Ohkawa Y., Ogawa A., Aoki J., et al. Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo. Circulation. 108:2003;1746-1752
5. Hayashi K., Takahashi M., Nishida W., Yoshida K., Ohkawa Y., Kitabatake A., et al. Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids. Circ. Res. 89:2001;251-258
6. Mills G.B., Moolenaar W.H. The emerging role of lysophosphatidic acid in cancer. Nat. Rev. Cancer. 3:2003;582-591
7. Hecht J.H., Weiner J.A., Post S.R., Chun J. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J. Cell Biol. 135:1996;1071-1083
8. An S., Bleu T., Hallmark O.G., Goetzl E.J. Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid. J. Biol. Chem. 273:1998;7906-7910
9. Bandoh K., Aoki J., Hosono H., Kobayashi S., Kobayashi T., Murakami M.K., et al. Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid [In Process Citation]. J. Biol. Chem. 274:1999;27776-27785
10. Noguchi K., Ishii S., Shimizu T. Identification of p2y9/GPR23 as a Novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family. J. Biol. Chem. 278:2003;25600-25606
11. Contos J.J., Ishii I., Chun J. Lysophosphatidic acid receptors. Mol. Pharmacol. 58:2000;1188-1196
12. Contos J.J., Fukushima N., Weiner J.A., Kaushal D., Chun J. Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proc. Natl. Acad. Sci USA. 97:2000;13384-13389
13. Contos J.J., Ishii I., Fukushima N., Kingsbury M.A., Ye X., Kawamura S., et al. Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Mol. Cell Biol. 22:2002;6921-6929
14. Hooks S.B., Santos W.L., Im D.S., Heise C.E., Macdonald T.L., Lynch K.R. Lysophosphatidic acid-induced mitogenesis is regulated by lipid phosphate phosphatases and is Edg-receptor independent. J. Biol. Chem. 276:2001;4611-4621
15. McIntyre T.M., Pontsler A.V., Silva A.R., Hilaire A., Xu Y., Hinshaw J.C., et al. Identification of an intracellular receptor forlysophosphatidic acid (LPA): LPA is a transcellular PPAR gamma agonist. Proc. Natl. Acad. Sci. USA. 100:2003;131-136
16. Tigyi G., Miledi R. Lysophosphatidates bound to serum albumin activate membrane currents in Xenopus oocytes and neurite retraction in PC12 pheochromocytoma cells. J. Biol. Chem. 267:1992;21360-21367
17. Baker D.L., Umstot E.S., Desiderio D.M., Tigyi G.J. Quantitative analysis of lysophosphatidic acid in human blood fractions. Ann. NY Acad. Sci. 905:2000;267-269
18. Sano T., Baker D.L., Virag T., Wada A., Yatomi Y., Kobayashi T., et al. Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine-1-phosphate generation in blood. J. Biol. Chem. 277:2002;21197-21206
19. Aoki J., Taira A., Takanezawa Y., Kishi Y., Hama K., Kishimoto T., et al. Serum lysophosphatidic acid is produced through diverse phospholipase pathways. J. Biol. Chem. 277:2002;39696-39702
20. Sugiura T., Nakane S., Kishimoto S., Waku K., Yoshioka Y., Tokumura A. Lysophosphatidic acid, a growth factor-like lipid, in the saliva. J. Lipid Res. 43:2002;2049-2055
21. Hama K., Bandoh K., Kakehi Y., Aoki J., Arai H. Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors. FEBS Lett. 523:2002;187-192
22. Tokumura A., Miyake M., Nishioka Y., Yamano S., Aono T., Fukuzawa K. Production of lysophosphatidic acids by lysophospholipase D in human follicular fluids of In vitro fertilization patients. Biol Reprod. 61:1999;195-199
23. Nakane S., Tokumura A., Waku K., Sugiura T. Hen egg yolk and white contain high amounts of lysophosphatidic acids, growth factor-like lipids: distinct molecular species compositions. Lipids. 36:2001;413-419
24. Xu Y., Gaudette D.C., Boynton J.D., Frankel A., Fang X.J., Sharma A., et al. Characterization of an ovarian cancer activating factor in ascites from ovarian cancer patients. Clin. Cancer Res. 1:1995;1223-1232
25. Mauco G., Chap H., Simon M.F., Douste B.L. Phosphatidic and lysophosphatidic acid production in phospholipase C- and thrombin-treated platelets. Possible involvement of a platelet lipase. Biochimie. 60:1978;653-661
26. Gerrard J.M., Robinson P. Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin. Biochim. Biophys. Acta. 1001:1989;282-285
27. Eichholtz T, Jalink K, Fahrenfort I, Moolenaar WH. The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem J 1993;677-80.
28. Gaits F., Fourcade O., Le B.F., Gueguen G., Gaige B., Gassama D.A., et al. Lysophosphatidic acid as a phospholipid mediator: pathways of synthesis. FEBS Lett. 410:1997;54-58
29. Tokumura A., Harada K., Fukuzawa K., Tsukatani H. Involvement of lysophospholipase D in the production of lysophosphatidic acid in rat plasma. Biochim. Biophys. Acta. 875:1986;31-38
30. Fourcade O., Simon M.F., Viode C., Rugani N., Leballe F., Ragab A., et al. Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells. Cell. 80:1995;919-927
31. Shen Z., Belinson J., Morton R.E., Xu Y., Xu Y. Phorbol 12-myristate 13-acetate stimulates lysophosphatidic acid secretion from ovarian and cervical cancer cells but not from breast or leukemia cells. Gynecol. Oncol. 71:1998;364-368
32. Eder A., Sasagawa T., Mao M., Aoki J., Mills G. Constitutive and LPA induced LPA production: role of PLD and PLA2. Clin. Cancer Res. 6:2000;2482-2491
33. Xie Y., Gibbs T.C., Mukhin Y.V., Meier K.E. Role for 18:1 lysophosphatidic acid as an autocrine mediator in prostate cancer cells. J. Biol. Chem. 277:2002;32516-32526
34. Dircks L., Sul H.S. Acyltransferases of de novo glycerophospholipid biosynthesis. Prog. Lipid Res. 38:1999;461-479
35. Xiao Y., Chen Y., Kennedy A.W., Belinson J., Xu Y. Evaluation of plasma lysophospholipids for diagnostic significance using electrospray ionization mass spectrometry (ESI-MS) analyses. Ann. N.Y. Acad. Sci. 905:2000;242-259
36. Baker D.L., Desiderio D.M., Miller D.D., Tolley B., Tigyi G.J. Direct quantitative analysis of lysophosphatidic acid molecular species by stable isotope dilution electrospray ionization liquid chromatography-mass spectrometry. Anal. Biochem. 292:2001;287-295
37. Tokumura A., Iimori M., Nishioka Y., Kitahara M., Sakashita M., Tanaka S. Lysophosphatidic acids induce proliferation of cultured vascular smooth muscle cells from rat aorta. Am. J. Physiol. 267:1994;C204-C210
38. Jalink K., Hengeveld T., Mulder S., Postma F.R., Simon M.F., Chap H., et al. Lysophosphatidic acid-induced Ca2+ mobilization in human A431 cells: structure-activity analysis. Biochem. J. 307:1995;609-616
39. Bandoh K., Aoki J., Taira A., Tsujimoto M., Arai H., Inoue K. Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species - structure-activity relationship of cloned LPA receptors. FEBS Lett. 478:2000;159-165
40. Murakami M., Kudo I. Phospholipase A2. J. Biochem. (Tokyo). 131:2002;285-292
41. 1 - structures, physiological and patho-physiological roles in mammals. In: Muller, Petry, editors. Lipases and Phospholipases in Drug Development: From biochemistry to molecular pharmacology. Wiley-VCH; 2004. p. 423-39.
42. Tokumura A., Miyake M., Yoshimoto O., Shimizu M., Fukuzawa K. Metal-ion stimulation and inhibition of lysophospholipase D which generates bioactive lysophosphatidic acid in rat plasma. Lipids. 33:1998;1009-1015
43. Tokumura A, Nishioka Y, Yoshimoto O, Shinomiya J, Fukuzawa K. Substrate specificity of lysophospholipase D which produces bioactive lysophosphatidic acids in rat plasma. Biochim Biophys Acta 1999;235-45.
44. Furukawa M., Muguruma K., Frenkel R.A., Johnston J.M. Metabolic fate of platelet-activating factor in the rat enterocyte: the role of a specific lysophospholipase D. Arch Biochem Biophys. 319:1995;274-280
45. Wykle R.L., Strum J.C. Lysophospholipase D. Methods Enzymol. 197:1991;583-590
46. Wilcox R.W., Wykle R.L., Schmitt J.D., Daniel L.W. The degradation of platelet-activating factor and related lipids: susceptibility to phospholipases C and D. Lipids. 22:1987;800-807
47. Wykle R.L., Kraemer W.F., Schremmer J.M. Studies of lysophospholipase D of rat liver and other tissues. Arch Biochem Biophys. 184:1977;149-155
48. Umezu G.M., Kishi Y., Taira A., Hama K., Dohmae N., Takio K., et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production. J. Cell Biol. 158:2002;227-233
49. Tokumura A. Physiological and pathophysiological roles of lysophosphatidic acids produced by secretory lysophospholipase D in body fluids. Biochim. Biophys. Acta. 1582:2002;18-25
50. Clair T., Aoki J., Koh E., Bandle R.W., Nam S.W., Ptaszynska M.M., et al. Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate. Cancer Res. 63:2003;5446-5453
51. Liliom K, Sun G, Bunemann M, Virag T, Nusser N, Baker DL, et al. Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors. Biochem J 2001;189-97.
52. Tokumura A., Kanaya Y., Kitahara M., Miyake M., Yoshioka Y., Fukuzawa K. Increased formation of lysophosphatidic acids by lysophospholipase D in serum of hypercholesterolemic rabbits. J. Lipid Res. 43:2002;307-315
53. Black EJ, Clair T, Delrow J, Neiman P, Gillespie DA. Microarray analysis identifies Autotaxin, a tumour cell motility and angiogenic factor with lysophospholipase D activity, as a specific target of cell transformation by v-Jun. Oncogene 2003.
54. Tokumura A., Majima E., Kariya Y., Tominaga K., Kogure K., Yasuda K., et al. Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase. J. Biol. Chem. 277:2002;39436-39442
55. Stracke M.L., Krutzsch H.C., Unsworth E.J., Arestad A., Cioce V., Schiffmann E., et al. Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein. J Biol Chem. 267:1992;2524-2529
56. Stracke M.L., Clair T., Liotta L.A. Autotaxin, tumor motility-stimulating exophosphodiesterase. Adv. Enzyme Regul. 37:1997;135-144
57. Imamura F., Horai T., Mukai M., Shinkai K., Sawada M., Akedo H. Induction of in vitro tumor cell invasion of cellular monolayers by lysophosphatidic acid or phospholipase D. Biochem. Biophys. Res. Commun. 193:1993;497-503
58. Stam J.C., Michiels F., van der Kammen R.A., et al. Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling. EMBO. J. 17:1998;4066-4074
59. Sturm A., Sudermann T., Schulte K.M., Goebell H., Dignass A.U. Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid. Gastroenterology. 117:1999;368-377
60. Manning T.J., Parker J.C., Sontheimer H. Role of lysophosphatidic acid and rho in glioma cell motility. Cell Motil. Cytoskeleton. 45:2000;185-199
61. Clair T., Lee H.Y., Liotta L.A., Stracke M.L. Autotaxin is an exoenzyme possessing 5′-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities. J. Biol. Chem. 272:1997;996-1001
62. Lee H.Y., Clair T., Mulvaney P.T., Woodhouse E.C., Aznavoorian S., Liotta L.A., et al. Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin. J. Biol. Chem. 271:1996;24408-24412
63. Hama K, Aoki J, Fukaya M, Kishi Y, Sakai T, Suzuki R, et al. Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1. J Biol Chem, in press.
64. Ohta H., Sato K., Murata N., Damirin A., Malchinkhuu E., Kon J., et al. Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors. Mol. Pharmacol. 64:2003;994-1005
65. Van Leeuwen F., Olivo C., Grivell S., Giepmans B.N., Collard J.G., Moolenaar W.H. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1. J. Biol. Chem. 278:2003;400-406
66. Shida D., Kitayama J., Yamaguchi H., Okaji Y., Tsuno N.H., Watanabe T., et al. Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1. Cancer Res. 63:2003;1706-1711
67. Yamada T, Sato K, Komachi M, Malchinkhuu E, Tobo M, Kimura T, et al. Lysophosphatidic acid in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1. J Biol Chem, in press.
68. 2+ signaling pathways. Curr. Biol. 8:1998;386-392
69. Van Meeteren L, Frederiks F, Giepmans BN, Fernandes PM, Billington SJ, Jost BH, et al. Spider and bacterial sphingomyelinases D target cellular LPA receptors by hydrolyzing lysophosphatidylcholine. J Biol Chem, in press.
70. Sekas G., Patton G.M., Lincoln E.C., Robins S.J. Origin of plasma lysophosphatidylcholine: evidence for direct hepatic secretion in the rat. J. Lab. Clin. Med. 105:1985;190-194
71. Tjoelker L.W., Wilder C., Eberhardt C., Stafforini D.M., Dietsch G., Schimpf B., et al. Anti-inflammatory properties of a platelet-activating factor acetylhydrolase [see comments]. Nature. 374:1995;549-553
72. Jonas A. Lecithin cholesterol acyltransferase. Biochim. Biophys. Acta. 1529:2000;245-256
73. Glomset JA, Assman G, Gjone E, Norum KR. The metabolic and molecular bases of inherited disease. 1995;1933-51.
74. Croset M., Brossard N., Polette A., Lagarde M. Characterization of plasma unsaturated lysophosphatidylcholines in human and rat. Biochem. J. 345:2000;61-67
75. Yokoyama K., Kudo I., Inoue K. Phospholipid degradation in rat calcium ionophore-activated platelets is catalyzed mainly by two discrete secretory phospholipase As. J. Biochem. 117:1995;1280-1287
76. Sato T., Aoki J., Nagai Y., Dohmae N., Takio K., Doi T., et al. Serine phospholipid-specific phospholipase A that is secreted from activated platelets. A new member of the lipase family. J. Biol. Chem. 272:1997;2192-2198
77. le Balle F., Simon M.F., Meijer S., Fourcade O., Chap H. Membrane sidedness of biosynthetic pathways involved in the production of lysophosphatidic acid. Adv Enzyme Regul. 39:1999;275-284
78. Murakami M., Kudo I. Diversity and regulatory functions of mammalian secretory phospholipase A2s. Adv. Immunol. 77:2001;163-194
79. Aoki J., Nagai Y., Hosono H., Inoue K., Arai H. Structure and function of phosphatidylserine-specific phospholipase A1. Biochim. Biophys. Acta. 1582:2002;26-32
80. Higgs H.N., Han M.H., Johnson G.E., Glomset J.A. Cloning of a phosphatidic acid-preferring phospholipase A1 from bovine testis. J. Biol. Chem. 273:1998;5468-5477
81. Nakajima K., Sonoda H., Mizoguchi T., Aoki J., Arai H., Nagahama M., et al. A novel phospholipase A1 with sequence homology to a mammalian Sec23p-interacting protein, p125. J. Biol. Chem. 277:2002;11329-11335
82. Tani K., Mizoguchi T., Iwamatsu A., Hatsuzawa K., Tagaya M. p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins. J. Biol. Chem. 274:1999;20505-20512
83. Kudo I., Murakami M. Phospholipase A2 enzymes. Prostaglandins Other Lipid Mediat. 69:2002;3-58
84. Arai H. Platelet-activating factor acetylhydrolase. Prostaglandins Other Lipid Mediat. 69:2003;83-94
85. Billah M.M., Lapetina E.G., Cuatrecasas P. Phospholipase A2 activity specific for phosphatidic acid. A possible mechanism for the production of arachidonic acid in platelets. J. Biol. Chem. 256:1981;5399-5403
86. Luquain C., Singh A., Wang L., Natarajan V., Morris A.J. Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells. J. Lipid Res. 44:2003;1963-1975
87. Exton J.H. Regulation of phospholipase D. FEBS Lett. 531:2002;58-61
88. Cummings R., Parinandi N., Wang L., Usatyuk P., Natarajan V. Phospholipase D/phosphatidic acid signal transduction: role and physiological significance in lung. Mol. Cell Biochem. 235:2002;99-109
89. Sonoda H., Aoki J., Hiramatsu T., Ishida M., Bandoh K., Nagai Y., et al. A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid. J. Biol. Chem. 277:2002;34254-34263
90. Hiramatsu T, Sonoda H, Takanezawa Y, Morikawa R, Ishida M, Kasahara K, et al. Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta. J Biol Chem, in press.
91. Topham M.K., Prescott S.M. Diacylglycerol kinases: regulation and signaling roles. Thromb. Haemost. 88:2003;912-918
92. Clark J.D., Lin L.L., Kriz R.W., Ramesha C.S., Sultzman L.A., Lin A.Y., et al. A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP. Cell. 65:1991;1043-1051
93. Underwood K.W., Song C., Kriz R.W., Chang X.J., Knopf J.L., Lin L.L. A novel calcium-independent phospholipase A2, cPLA2-gamma. J. Biol. Chem. 273:1998;21926-21932
94. Pickard R.T., Strifler B.A., Kramer R.M., Sharp J.D. Molecular cloning of two new human paralogs of 85-kDa cytosolic phospholipase A2. J Biol Chem. 274:1999;8823-8831
95. Tang J., Kriz R.W., Wolfman N., Shaffer M., Seehra J., Jones S.S. A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs. J. Biol. Chem. 272:1997;8567-8575
96. Mancuso D.J., Jenkins C.M., Gross R.W. The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A(2). J. Biol. Chem. 275:2000;9937-9945
97. Snitko Y, Yoon ET, Cho W. High specificity of human secretory class II phospholipase A2 for phosphatidic acid. Biochem J 1997;737-41.
98. Kokusho Y., Tsunoda A., Kato S., Machida H., Iwasaki S. Production of various phosphatidylsaccharides by phospholipase D from Actinomadura sp. strain no. 362. Biosci. Biotechnol. Biochem. 57:1993;1302-1305
99. Hodgkin MN, Clark JM, Rose S, Saqib K, Wakelam MJ. Characterization of the regulation of phospholipase D activity in the detergent-insoluble fraction of HL60 cells by protein kinase C and small G-proteins. Biochem J 1999;87-93.
100. Czarny M., Lavie Y., Fiucci G., Liscovitch M. Localization of phospholipase D in detergent-insoluble, caveolin-rich membrane domains. Modulation by caveolin-1 expression and caveolin-182-101. J. Biol. Chem. 274:1999;2717-2724
101. Walker A.J., Draeger A., Houssa B., van B.W., Ohanian V., Ohanian J. Diacylglycerol kinase theta is translocated and phosphoinositide 3-kinase-dependently activated by noradrenaline but not angiotensin II in intact small arteries. Biochem. J. 353:2001;129-137
102. Sciorra V.A., Morris A.J. Sequential actions of phospholipase D and phosphatidic acid phosphohydrolase 2b generate diglyceride in mammalian cells. Mol Biol Cell. 10:1999;3863-3876
103. Nanjundan M, Possmayer F. Pulmonary lipid phosphate phosphohydrolase in plasma membrane signalling platforms. Biochem J 2001;637-46.