New 3-[4-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]-1-(5-substituted benzo[b]thiophen-3-yl)propanol derivatives with dual action at 5-HT 1A serotonin receptors and serotonin transporter as a new class of antidepressants

Pharmazie

Volumn 59, Issue 7, 2004, Pages 499-501

  Perez Silanes S ^a   Orus L ^a   Oficialdegui, A M ^a   Martinez Esparza J ^a   Lasheras, B ^a   Del Rio J ^a   Monge, Antonio ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 HYDROXYBENZO[B]THIOPHEN 3 YL) 3 [4 (2,3 DIHYDRO 1,4 BENZODIOXIN 5 YL)PIPERAZIN 1 YL]PROPAN 1 OL; 1 (5 NITROBENZO[B]THIOPHEN 3 YL) 3 [4 (2,3 DIHYDRO 1,4 BENZODIOXIN 5 YL)PIPERAZIN 1 YL]PROPAN 1 OL; ANTIDEPRESSANT AGENT; BENZOTHIOPHENE DERIVATIVE; PIPERAZINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; RADIOASSAY; RECEPTOR AFFINITY;

ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BINDING, COMPETITIVE; CARRIER PROTEINS; CHEMISTRY, PHYSICAL; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; PIPERAZINES; PROPANOLS; RATS; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; THIOPHENES;

EID: 3242679004     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

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