Plant "polyphenolic" small molecules can induce a calorie restriction-mimetic life-span extension by activating sirtuins: Will "polyphenols" someday be used as chemotherapeutic drugs in western medicine?

ChemBioChem

Volumn 5, Issue 4, 2004, Pages 427-430

  Quideau, Stéphane ^a,b  

^a INSTITUT EUROPÉEN DE CHIMIE ET BIOLOGIE   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Biological activity; Enzymes; Longevity; Natural products; Polyphenols; Sirtuins

Indexed keywords

3,6,2',4' TETRAHYDROXYFLAVONE; ANTHOCYANIN; BUTEIN; CHALCONE DERIVATIVE; FISETIN; FLAVANOL DERIVATIVE; FLAVANONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; ISOFLAVONE DERIVATIVE; OLIGOMER; PICEATANNOL; POLYMER; POLYPHENOL DERIVATIVE; QUERCETIN; RESVERATROL; SIRTUIN; UNCLASSIFIED DRUG; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS;

ANTIOXIDANT ACTIVITY; CALORIC RESTRICTION; CHEMICAL STRUCTURE; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; LIFE EXPECTANCY; LIFESPAN; MOLECULAR SIZE; MOLECULAR WEIGHT; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; ANIMAL; ARTICLE; CHEMISTRY; LONGEVITY; METABOLISM; PHYSIOLOGY; PHYTOTHERAPY;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

ANIMALS; CALORIC RESTRICTION; FLAVONOIDS; HUMANS; LONGEVITY; PHENOLS; PHYTOTHERAPY; PLANT EXTRACTS; SIRTUINS;

EID: 3242676146     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200300835     Document Type: Review

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