-
1
-
-
84956427297
-
A direct measurement of radiation sensitivity of normal mouse bone marrow cells
-
Till JE, McCulloch EA: A direct measurement of radiation sensitivity of normal mouse bone marrow cells. Radiat Res 1961, 14:213-222.
-
(1961)
Radiat Res
, vol.14
, pp. 213-222
-
-
Till, J.E.1
McCulloch, E.A.2
-
2
-
-
78651158197
-
A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells
-
Till JE, McCulloch EA, Siminovitch L: A stochastic model of stem cell proliferation, based on the growth of spleen colony-forming cells. Proc Natl Acad Sci U S A 1964, 51:29-36.
-
(1964)
Proc Natl Acad Sci U S A
, vol.51
, pp. 29-36
-
-
Till, J.E.1
McCulloch, E.A.2
Siminovitch, L.3
-
5
-
-
0030065744
-
Evidence that hematopoiesis may be a stochastic process in vivo
-
Abkowitz JL, Catlin SN, Guttorp P: Evidence that hematopoiesis may be a stochastic process in vivo. Nat Med 1996, 2:190-197.
-
(1996)
Nat Med
, vol.2
, pp. 190-197
-
-
Abkowitz, J.L.1
Catlin, S.N.2
Guttorp, P.3
-
6
-
-
0025801487
-
A stochastic branching model with formation of subunits applied to the growth of intestinal crypts
-
Loeffler M, Grossmann B: A stochastic branching model with formation of subunits applied to the growth of intestinal crypts. J Theor Biol 1991, 150:175-191.
-
(1991)
J Theor Biol
, vol.150
, pp. 175-191
-
-
Loeffler, M.1
Grossmann, B.2
-
7
-
-
0038819885
-
Stem-cell hierarchy in skin cancer
-
Perez-Losada J, Balmain A: Stem-cell hierarchy in skin cancer. Nat Rev Cancer 2003, 3:434-443.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 434-443
-
-
Perez-Losada, J.1
Balmain, A.2
-
8
-
-
1642580868
-
Radiation, the ideal cytotoxic agent for studying the cell biology of tissues such as the small intestine
-
Potten CS: Radiation, the ideal cytotoxic agent for studying the cell biology of tissues such as the small intestine. Radiat Res 2004, 161:123-136.
-
(2004)
Radiat Res
, vol.161
, pp. 123-136
-
-
Potten, C.S.1
-
9
-
-
0037327196
-
Mathemalical models of hierarchically structured cell populations under equilibrium with application to the epidermis
-
Savill NJ: Mathemalical models of hierarchically structured cell populations under equilibrium with application to the epidermis. Cell Prolif 2003, 36:1-26.
-
(2003)
Cell Prolif
, vol.36
, pp. 1-26
-
-
Savill, N.J.1
-
11
-
-
84982560407
-
A comprehensive mathematical model of stem cell proliferation which reproduces most of the published experimental results
-
Loeffler M, Wichmann HE: A comprehensive mathematical model of stem cell proliferation which reproduces most of the published experimental results. Cell Tissue Kinet 1980, 13:543-561.
-
(1980)
Cell Tissue Kinet
, vol.13
, pp. 543-561
-
-
Loeffler, M.1
Wichmann, H.E.2
-
13
-
-
0036098242
-
Tissue stem cells: Definition, plasticity, heterogeneity, self-organizafion and models - A conceptual approach
-
Loeffler M, Roeder I: Tissue stem cells: definition, plasticity, heterogeneity, self-organizafion and models - a conceptual approach. Cell Tissues Organs 2002, 171:8-26.
-
(2002)
Cell Tissues Organs
, vol.171
, pp. 8-26
-
-
Loeffler, M.1
Roeder, I.2
-
14
-
-
0025641727
-
Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
-
Potten CS, Loeffler M: Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development 1990, 110:1001-1020.
-
(1990)
Development
, vol.110
, pp. 1001-1020
-
-
Potten, C.S.1
Loeffler, M.2
-
15
-
-
0032433677
-
Stem cell homing: Rolling, crawling, and nesting
-
Quesenberry PJ, Becker PS: Stem cell homing: rolling, crawling, and nesting. Proc Natl Acad Sci U S A 1998, 95:15155-15157.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15155-15157
-
-
Quesenberry, P.J.1
Becker, P.S.2
-
16
-
-
0033533822
-
Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors
-
Rolink AG, Nutt SL, Melchers F, et al.: Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors [see comments]. Nature 1999, 401:603-606.
-
(1999)
Nature
, vol.401
, pp. 603-606
-
-
Rolink, A.G.1
Nutt, S.L.2
Melchers, F.3
-
17
-
-
0032857031
-
Reversible expression of CD34 by murine hematopoietic stem cells
-
Sato T, Laver JH, Ogawa M: Reversible expression of CD34 by murine hematopoietic stem cells. Blood 1999, 94:2548-2554.
-
(1999)
Blood
, vol.94
, pp. 2548-2554
-
-
Sato, T.1
Laver, J.H.2
Ogawa, M.3
-
18
-
-
0035103997
-
The fleet feet of haematopoietic stem cells: Rapid motility, interaction and proteopodia
-
Frimberger AE, McAuliffe CI, Werme KA, et al.: The fleet feet of haematopoietic stem cells: rapid motility, interaction and proteopodia. Br J Haematol 2001, 112:644-654.
-
(2001)
Br J Haematol
, vol.112
, pp. 644-654
-
-
Frimberger, A.E.1
McAuliffe, C.I.2
Werme, K.A.3
-
19
-
-
0035207122
-
Physical and physiological plasticity of hematopoietic stem cells
-
Quesenberry P, Habibian H, Dooner M, et al.: Physical and physiological plasticity of hematopoietic stem cells. Blood Cell Mol Dis 2001, 27:934-937.
-
(2001)
Blood Cell Mol Dis
, vol.27
, pp. 934-937
-
-
Quesenberry, P.1
Habibian, H.2
Dooner, M.3
-
20
-
-
1042291172
-
Intrinsic hematopoietic stem cell/progenitor plasticity: Inversions
-
Colvin GA, Lambert JF, Moore BE, et al.: Intrinsic hematopoietic stem cell/progenitor plasticity: inversions. J Cell Physiol 2004, 199:20-31.
-
(2004)
J Cell Physiol
, vol.199
, pp. 20-31
-
-
Colvin, G.A.1
Lambert, J.F.2
Moore, B.E.3
-
22
-
-
1542328965
-
Plasticity of adult stem cells
-
Wagers AJ, Weissman IL: Plasticity of adult stem cells. Cell 2004, 116:639-648.
-
(2004)
Cell
, vol.116
, pp. 639-648
-
-
Wagers, A.J.1
Weissman, I.L.2
-
23
-
-
0037961737
-
Stem-cell "plasticity": Befuddled by the muddle
-
Goodell MA: Stem-cell "plasticity": befuddled by the muddle. Curr Opin Hematol 2003, 10:208-213.
-
(2003)
Curr Opin Hematol
, vol.10
, pp. 208-213
-
-
Goodell, M.A.1
-
24
-
-
0035273648
-
Stem cell dogmas in the genomics era
-
Lemischka I: Stem cell dogmas in the genomics era. Rev Clin Exp Hematol 2001, 5:15-25.
-
(2001)
Rev Clin Exp Hematol
, vol.5
, pp. 15-25
-
-
Lemischka, I.1
-
25
-
-
0036322347
-
A few thoughts about the plasticity of stem cells
-
Lemischka I: A few thoughts about the plasticity of stem cells. Exp Hematol 2002, 30:848-852.
-
(2002)
Exp Hematol
, vol.30
, pp. 848-852
-
-
Lemischka, I.1
-
26
-
-
0033756981
-
Stem cell plasticity in mammals and transdetermination in Drosophila: Common themes?
-
Wei G, Schubiger G, Harder F, Muller AM: Stem cell plasticity in mammals and transdetermination in Drosophila: common themes? Stem Cells 2000, 18:409-414.
-
(2000)
Stem Cells
, vol.18
, pp. 409-414
-
-
Wei, G.1
Schubiger, G.2
Harder, F.3
Muller, A.M.4
-
27
-
-
0035967892
-
The evolving concept of a stem cell: Entity or function?
-
Blau HM, Brazelton TR, Weimann JM: The evolving concept of a stem cell: entity or function? Cell 2001, 105:829-841.
-
(2001)
Cell
, vol.105
, pp. 829-841
-
-
Blau, H.M.1
Brazelton, T.R.2
Weimann, J.M.3
-
28
-
-
0742306885
-
Differentiation hotspots: The deterioration of hierarchy and stochasm
-
Colvin GA, Lambert JF, Abedi M, et al.: Differentiation hotspots: the deterioration of hierarchy and stochasm. Blood Cell Mol Dis 2004, 32:34-41. This is a comprehensive overview of new insights in the field of hematopoietic stem cell biology. The article summarizes experimental results, biologic hypothesis, as well as conceptual viewpoints and mathematic modeling approaches.
-
(2004)
Blood Cell Mol Dis
, vol.32
, pp. 34-41
-
-
Colvin, G.A.1
Lambert, J.F.2
Abedi, M.3
-
30
-
-
0025176833
-
Clonal and systemic analysis of long-term hematopoiesis in the mouse
-
Jordan CT, Lemischka IR: Clonal and systemic analysis of long-term hematopoiesis in the mouse. Genes Dev 1990, 4:220-232.
-
(1990)
Genes Dev
, vol.4
, pp. 220-232
-
-
Jordan, C.T.1
Lemischka, I.R.2
-
31
-
-
0025376130
-
Long- and short-lived murine hematopoietic stem cell clones individually identified with retroviral integration markers
-
Capel B, Hawley RG, Mintz B: Long- and short-lived murine hematopoietic stem cell clones individually identified with retroviral integration markers. Blood 1990, 75:2267-2270.
-
(1990)
Blood
, vol.75
, pp. 2267-2270
-
-
Capel, B.1
Hawley, R.G.2
Mintz, B.3
-
32
-
-
0031036639
-
Long-term maintenance of hematopoiesis in irradiated mice by retrovirally transduced peripheral blood stem cells
-
Drize N, Chertkov J, Sadovnikova E, et al.: Long-term maintenance of hematopoiesis in irradiated mice by retrovirally transduced peripheral blood stem cells. Blood 1997, 89:1811-1817.
-
(1997)
Blood
, vol.89
, pp. 1811-1817
-
-
Drize, N.1
Chertkov, J.2
Sadovnikova, E.3
-
33
-
-
0002234927
-
Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates
-
Kim HJ, Tisdale JF, Wu T, et al.: Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates. Blood 2000, 96:1-8.
-
(2000)
Blood
, vol.96
, pp. 1-8
-
-
Kim, H.J.1
Tisdale, J.F.2
Wu, T.3
-
34
-
-
0034669933
-
In vivo kinetics of murine hemopoietic stem cells
-
Abkowitz JL, Golinelli D, Harrison DE, et al.: In vivo kinetics of murine hemopoietic stem cells. Blood 2000, 96:3399-3405.
-
(2000)
Blood
, vol.96
, pp. 3399-3405
-
-
Abkowitz, J.L.1
Golinelli, D.2
Harrison, D.E.3
-
35
-
-
0034545695
-
Autonomous behavior of hematopoietic stem cells
-
Kamminga LM, Akkerman I, Weersing E, et al.: Autonomous behavior of hematopoietic stem cells. Exp Hematol 2000, 28:1451-1459.
-
(2000)
Exp Hematol
, vol.28
, pp. 1451-1459
-
-
Kamminga, L.M.1
Akkerman, I.2
Weersing, E.3
-
38
-
-
9144226389
-
Molecular signatures of self-renewal, differentiation, and lineage choice in multipotential hemopoietic progenitor cells in vitro
-
Bruno L, Hoffmann R, McBlane F, et al.: Molecular signatures of self-renewal, differentiation, and lineage choice in multipotential hemopoietic progenitor cells in vitro. Mol Cell Biol 2004, 24:741-756.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 741-756
-
-
Bruno, L.1
Hoffmann, R.2
McBlane, F.3
-
39
-
-
0034303586
-
Diversification of haematopoietic stem cells to specific lineages
-
Orkin SH: Diversification of haematopoietic stem cells to specific lineages. Nat Rev Genet 2000, 1:57-64.
-
(2000)
Nat Rev Genet
, vol.1
, pp. 57-64
-
-
Orkin, S.H.1
-
40
-
-
0142158836
-
T-lineage specification and commitment: A gene regulation perspective
-
Rothenberg EV: T-lineage specification and commitment: a gene regulation perspective. Semin Immunol 2002, 14:431-440.
-
(2002)
Semin Immunol
, vol.14
, pp. 431-440
-
-
Rothenberg, E.V.1
-
43
-
-
0036370668
-
The universal properties of stem cells as pin-pointed by a simple discrete model
-
Agur Z, Daniel Y, Ginosar Y: The universal properties of stem cells as pin-pointed by a simple discrete model. J Math Biol 2002, 44:79-86.
-
(2002)
J Math Biol
, vol.44
, pp. 79-86
-
-
Agur, Z.1
Daniel, Y.2
Ginosar, Y.3
-
44
-
-
0035030264
-
Cell kinetic status of haematopoietic stem cells
-
Mackey MC: Cell kinetic status of haematopoietic stem cells. Cell Prolif 2001, 34:71-83.
-
(2001)
Cell Prolif
, vol.34
, pp. 71-83
-
-
Mackey, M.C.1
-
45
-
-
0037678721
-
Oscillations in cyclical neutropenia: New evidence based on mathematical modeling
-
Bernard S, Belair J, Mackey MC: Oscillations in cyclical neutropenia: new evidence based on mathematical modeling. J Theor Biol 2003, 223:283-298. This paper details the application of a simple mathematic model of stem cell activation and silencing that is able to explain a variety of results on cycling activity of stem cells obtained from different kinds of labeling studies.
-
(2003)
J Theor Biol
, vol.223
, pp. 283-298
-
-
Bernard, S.1
Belair, J.2
Mackey, M.C.3
-
46
-
-
0036788712
-
Evidence that the number of hematopoietic stem cells per animal is conserved in mammals
-
Abkowitz JL, Catlin SN, McCallie MT, et al.: Evidence that the number of hematopoietic stem cells per animal is conserved in mammals. Blood 2002, 100:2665-2667.
-
(2002)
Blood
, vol.100
, pp. 2665-2667
-
-
Abkowitz, J.L.1
Catlin, S.N.2
McCallie, M.T.3
-
47
-
-
0035024676
-
Statistical inference in a two-compartment model for hematopoiesis
-
Catlin SN, Abkowitz JL, Guttorp P: Statistical inference in a two-compartment model for hematopoiesis. Biometrics 2001, 57:546-553.
-
(2001)
Biometrics
, vol.57
, pp. 546-553
-
-
Catlin, S.N.1
Abkowitz, J.L.2
Guttorp, P.3
-
48
-
-
3242712669
-
Hematopoiesis as a competitive exclusion process: Estimation of a stem cell selective advantage
-
in press
-
Catlin SN, Guttorp P, McCallie MT, et al.: Hematopoiesis as a competitive exclusion process: estimation of a stem cell selective advantage. J Agricult Biol Environment Stat 2004, in press. This paper delineates the application of the quantitative, individual cell-based model by Abkowitz et al. [5]. The authors give a model-based explanation of chimerism skewing in cats resulting from small differences in cell kinetic properties between cells of different genetic background.
-
(2004)
J Agricult Biol Environment Stat
-
-
Catlin, S.N.1
Guttorp, P.2
McCallie, M.T.3
-
49
-
-
0036322106
-
A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity
-
Roeder I, Loeffler M: A novel dynamic model of hematopoietic stem cell organization based on the concept of within-tissue plasticity. Exp Hematol 2002, 30:853-861.
-
(2002)
Exp Hematol
, vol.30
, pp. 853-861
-
-
Roeder, I.1
Loeffler, M.2
-
50
-
-
3242672888
-
Biased and unbiased clonal competition application of a new dynamical model of stem cell organization
-
Loeffler M, Roeder I, Braesel K, et al.: Biased and unbiased clonal competition application of a new dynamical model of stem cell organization. Blood 2003, 102:1231a.
-
(2003)
Blood
, vol.102
-
-
Loeffler, M.1
Roeder, I.2
Braesel, K.3
-
51
-
-
0037114699
-
The chiaroscuro stem cell: A unified stem cell theory
-
Quesenberry PJ, Colvin GA, Lambert JF: The chiaroscuro stem cell: a unified stem cell theory. Blood 2002, 100:4266-4271.
-
(2002)
Blood
, vol.100
, pp. 4266-4271
-
-
Quesenberry, P.J.1
Colvin, G.A.2
Lambert, J.F.3
-
52
-
-
10744229835
-
The marrow stem cell: The continuum
-
Quesenberry PJ, Colvin GA, Abedi M, et al.: The marrow stem cell: the continuum. Bone Marrow Transplant 2003, 32(suppl 1):19-22. This article provides a description of a new biologic concept that includes plasticity and flexibility of cellular properties in stem cells. Based on a series of experimental results, the authors proposed molecular processes responsible for reversibly changing stem cell phenotype (see also Quesenberry et al. [51]).
-
(2003)
Bone Marrow Transplant
, vol.32
, Issue.1 SUPPL.
, pp. 19-22
-
-
Quesenberry, P.J.1
Colvin, G.A.2
Abedi, M.3
-
53
-
-
0034902642
-
Cell migration and organization in the intestinal crypt using a lattice-free model
-
Meineke FA, Pollen CS, Loeffler M: Cell migration and organization in the intestinal crypt using a lattice-free model. Cell Prolif 2001, 34:253-266.
-
(2001)
Cell Prolif
, vol.34
, pp. 253-266
-
-
Meineke, F.A.1
Pollen, C.S.2
Loeffler, M.3
-
54
-
-
0035257731
-
Vertebrate neural cell-fate determination: Lessons from the retina
-
Livesey FJ, Cepko CL: Vertebrate neural cell-fate determination: lessons from the retina. Nat Rev Neurosci 2001, 2:109-118.
-
(2001)
Nat Rev Neurosci
, vol.2
, pp. 109-118
-
-
Livesey, F.J.1
Cepko, C.L.2
-
55
-
-
0348231980
-
Perspective: Stem cells react! Cell lineages as complex adaptive systems
-
Theise ND: Perspective: stem cells react! Cell lineages as complex adaptive systems. Exp Hematol 2004, 32:25-27. The author discusses evidence that stem cell populations have to be understood as self-organizing systems. He highlights the necessity of new concepts (including quantitative models) to understand current experimental results in stem cell biology.
-
(2004)
Exp Hematol
, vol.32
, pp. 25-27
-
-
Theise, N.D.1
-
56
-
-
0742272117
-
Understanding cell lineages as complex adaptive systems
-
Theise ND, d'Inverno MD: Understanding cell lineages as complex adaptive systems. Blood Cell Mol Dis 2004, 32:17-20.
-
(2004)
Blood Cell Mol Dis
, vol.32
, pp. 17-20
-
-
Theise, N.D.1
D'Inverno, M.D.2
-
57
-
-
0042243492
-
Quantitative tissue stem cell modeling
-
reply, 1144-1145.
-
Roeder I, Loeffler M, Quesenberry PJ, et al.: Quantitative tissue stem cell modeling. Blood 2003, 102:1143-1144; reply, 1144-1145. This paper highlights the potential of quantitative modeling approaches. It relates the quantitative stem cell model proposed by Roeder and Loeffler [49] to the qualitative concept suggested by Quesenberry et al. [51], and demonstrales how simulation studies can help to explain experimental observations.
-
(2003)
Blood
, vol.102
, pp. 1143-1144
-
-
Roeder, I.1
Loeffler, M.2
Quesenberry, P.J.3
-
58
-
-
0742324498
-
The conceptual application of systems theory to stem cell biology: A matter of context
-
Flake AW: The conceptual application of systems theory to stem cell biology: a matter of context. Blood Cell Mol Dis 2004, 32:58-64. This conceptual discourse focuses on content- and method-specific interpretation of experimental results.
-
(2004)
Blood Cell Mol Dis
, vol.32
, pp. 58-64
-
-
Flake, A.W.1
-
59
-
-
0033533157
-
Isologous diversification for robust development of cell society
-
Kaneko K, Yomo T: Isologous diversification for robust development of cell society. J Theor Biol 1999, 199:243-256.
-
(1999)
J Theor Biol
, vol.199
, pp. 243-256
-
-
Kaneko, K.1
Yomo, T.2
-
60
-
-
0035925930
-
Theory of robustness of irreversible differentiation in a stem cell system: Chaos hypothesis
-
Furusawa C, Kaneko K: Theory of robustness of irreversible differentiation in a stem cell system: chaos hypothesis. J Theor Biol 2001, 209:395-416.
-
(2001)
J Theor Biol
, vol.209
, pp. 395-416
-
-
Furusawa, C.1
Kaneko, K.2
-
61
-
-
0042383441
-
Robust development as a consequence of generated positional information
-
Furusawa C, Kaneko K: Robust development as a consequence of generated positional information. J Theor Biol 2003, 224:413-435. In this important theoretic work, the authors demonstrate how the interaction of intracellular dynamics and extracellular gradients of chemical concentrations is able to generate stabilized cell societies that allow for dynamic regeneration after disturbance as well as emergence of dedifferentiation events.
-
(2003)
J Theor Biol
, vol.224
, pp. 413-435
-
-
Furusawa, C.1
Kaneko, K.2
-
62
-
-
0142061064
-
Stem cells: To be and not to be
-
Lin H: Stem cells: to be and not to be. Nature 2003, 425:353-355.
-
(2003)
Nature
, vol.425
, pp. 353-355
-
-
Lin, H.1
-
63
-
-
0242496395
-
Asymmetric cell division during neurogenesis in Drosophila and vertebrates
-
Wodarz A, Huttner WB: Asymmetric cell division during neurogenesis in Drosophila and vertebrates. Mech Dev 2003, 120:1297-1309.
-
(2003)
Mech Dev
, vol.120
, pp. 1297-1309
-
-
Wodarz, A.1
Huttner, W.B.2
|