메뉴 건너뛰기




Volumn 97, Issue 2, 2004, Pages 689-696

Suppressing lipolysis increases interleukin-6 at rest and during prolonged moderate-intensity exercise in humans

Author keywords

Cytokines; Fat metabolism; Nicotinic acid; Skeletal muscle

Indexed keywords

ADRENALIN; CARBOHYDRATE; FATTY ACID; GLUCOSE; GLYCOGEN; GROWTH HORMONE; HYDROCORTISONE; INSULIN; INTERLEUKIN 6; LACTIC ACID; MESSENGER RNA;

EID: 3242661646     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00195.2004     Document Type: Article
Times cited : (29)

References (45)
  • 1
    • 0036348603 scopus 로고    scopus 로고
    • Growth hormone administration reduces circulating proinflammatory cytokines and soluble Fas/soluble Fas ligand system in patients with chronic heart failure secondary to idiopathic dilated cardiomyopathy
    • Adamopoulos S, Parissis JT, Georgiadis M, Karatzas D, Paraskevaidis J, Kroupis C, Karavolias G, Koniavitou K, and Kremastinos DT. Growth hormone administration reduces circulating proinflammatory cytokines and soluble Fas/soluble Fas ligand system in patients with chronic heart failure secondary to idiopathic dilated cardiomyopathy. Am Heart J 144: 359-364, 2002.
    • (2002) Am Heart J , vol.144 , pp. 359-364
    • Adamopoulos, S.1    Parissis, J.T.2    Georgiadis, M.3    Karatzas, D.4    Paraskevaidis, J.5    Kroupis, C.6    Karavolias, G.7    Koniavitou, K.8    Kremastinos, D.T.9
  • 2
    • 0014471099 scopus 로고
    • Effect of nicotinic acid on physical working capacity and on metabolism of muscle glycogen in man
    • Bergström J, Hultman E, Jorfeldt L, Pernow B, and Wahren J. Effect of nicotinic acid on physical working capacity and on metabolism of muscle glycogen in man. J Appl Physiol 26: 170-176, 1969.
    • (1969) J Appl Physiol , vol.26 , pp. 170-176
    • Bergström, J.1    Hultman, E.2    Jorfeldt, L.3    Pernow, B.4    Wahren, J.5
  • 3
    • 0001479766 scopus 로고
    • Effect of nicotinic acid on the turnover rate and oxidation of the free fatty acids of plasma in man during exercise
    • Carlson LA, Havel RJ, Ekelund LG, and Holmgren A. Effect of nicotinic acid on the turnover rate and oxidation of the free fatty acids of plasma in man during exercise. Metabolism 12: 837-845, 1963.
    • (1963) Metabolism , vol.12 , pp. 837-845
    • Carlson, L.A.1    Havel, R.J.2    Ekelund, L.G.3    Holmgren, A.4
  • 4
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 6
    • 0033983466 scopus 로고    scopus 로고
    • Regulation of lipolysis and leptin biosynthesis in rodent adipose tissue by growth hormone
    • Fain JN and Bahouth SW. Regulation of lipolysis and leptin biosynthesis in rodent adipose tissue by growth hormone. Metabolism 49: 239-244, 2000.
    • (2000) Metabolism , vol.49 , pp. 239-244
    • Fain, J.N.1    Bahouth, S.W.2
  • 7
    • 0034493114 scopus 로고    scopus 로고
    • HSP72 gene expression progressively increases in human skeletal muscle during prolonged, exhaustive exercise
    • Febbraio MA and Koukoulas I. HSP72 gene expression progressively increases in human skeletal muscle during prolonged, exhaustive exercise. J Appl Physiol 89: 1055-1060, 2000.
    • (2000) J Appl Physiol , vol.89 , pp. 1055-1060
    • Febbraio, M.A.1    Koukoulas, I.2
  • 9
    • 0036720342 scopus 로고    scopus 로고
    • Muscle-derived interleukin-6: Mechanisms for activation and possible biological roles
    • Febbraio MA and Pedersen BK. Muscle-derived interleukin-6: mechanisms for activation and possible biological roles. FASEB J 16: 1335-1347, 2002.
    • (2002) FASEB J , vol.16 , pp. 1335-1347
    • Febbraio, M.A.1    Pedersen, B.K.2
  • 12
    • 0019795640 scopus 로고
    • Availability of glycogen and plasma NEFA for substrate utilisation in leg muscle of man during exercise
    • Gollnick PD, Pernow B, Essen B, Jansson E, and Saltin B. Availability of glycogen and plasma NEFA for substrate utilisation in leg muscle of man during exercise. Clin Physiol 1: 27-42, 1981.
    • (1981) Clin Physiol , vol.1 , pp. 27-42
    • Gollnick, P.D.1    Pernow, B.2    Essen, B.3    Jansson, E.4    Saltin, B.5
  • 13
    • 0034488243 scopus 로고    scopus 로고
    • Effect of altering substrate availability on metabolism and performance during intense exercise
    • Hawley JA, Burke LM, Angus DJ, Fallon KE, Martin DT, and Febbraio MA. Effect of altering substrate availability on metabolism and performance during intense exercise. Br J Nutr 84: 829-838, 2000.
    • (2000) Br J Nutr , vol.84 , pp. 829-838
    • Hawley, J.A.1    Burke, L.M.2    Angus, D.J.3    Fallon, K.E.4    Martin, D.T.5    Febbraio, M.A.6
  • 14
    • 0037236935 scopus 로고    scopus 로고
    • The effect of graded exercise on IL-6 release and glucose uptake in human skeletal muscle
    • Helge JW, Stallknecht B, Pedersen BK, Galbo H, Kiens B, and Richter EA. The effect of graded exercise on IL-6 release and glucose uptake in human skeletal muscle. J Physiol 546: 299-305, 2003.
    • (2003) J Physiol , vol.546 , pp. 299-305
    • Helge, J.W.1    Stallknecht, B.2    Pedersen, B.K.3    Galbo, H.4    Kiens, B.5    Richter, E.A.6
  • 15
    • 0042766372 scopus 로고    scopus 로고
    • Cytokine regulation of lipolysis in humans?
    • Jensen MD. Cytokine regulation of lipolysis in humans? J Clin Endocrinol Metab 88: 3003-3004, 2003.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 3003-3004
    • Jensen, M.D.1
  • 17
    • 0041473841 scopus 로고    scopus 로고
    • IL-6 gene expression in human adipose tissue in response to exercise-effect of carbohydrate ingestion
    • Keller C, Keller P, Marshal S, and Pedersen BK. IL-6 gene expression in human adipose tissue in response to exercise-effect of carbohydrate ingestion. J Physiol 550: 927-31, 2003.
    • (2003) J Physiol , vol.550 , pp. 927-931
    • Keller, C.1    Keller, P.2    Marshal, S.3    Pedersen, B.K.4
  • 18
    • 0035651023 scopus 로고    scopus 로고
    • Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: Influence of muscle glycogen content
    • Keller C, Steensberg A, Pilegaard H, Osada T, Saltin B, Pedersen BK, and Neufer PD. Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content. FASEB J 15: 2748-2750, 2001.
    • (2001) FASEB J , vol.15 , pp. 2748-2750
    • Keller, C.1    Steensberg, A.2    Pilegaard, H.3    Osada, T.4    Saltin, B.5    Pedersen, B.K.6    Neufer, P.D.7
  • 19
    • 0043236220 scopus 로고    scopus 로고
    • Cortisol responses to mild psychological stress are inversely associated with proinflammatory cytokines
    • Kunz-Ebrecht SR, Mohamed-Ali V, Feldman PJ, Kirschbaum C, and Steptoe A. Cortisol responses to mild psychological stress are inversely associated with proinflammatory cytokines. Brain Behav Immun 17: 373-383, 2003.
    • (2003) Brain Behav Immun , vol.17 , pp. 373-383
    • Kunz-Ebrecht, S.R.1    Mohamed-Ali, V.2    Feldman, P.J.3    Kirschbaum, C.4    Steptoe, A.5
  • 20
    • 0036687485 scopus 로고    scopus 로고
    • Substantial elevation of interleukin-6 concentration in peritendonous tissue, in contrast to muscle, following prolonged exercise in humans
    • Langberg H, Olesen JL, Gemmer C, and Kjær M. Substantial elevation of interleukin-6 concentration in peritendonous tissue, in contrast to muscle, following prolonged exercise in humans. J Physiol 542: 985-990, 2002.
    • (2002) J Physiol , vol.542 , pp. 985-990
    • Langberg, H.1    Olesen, J.L.2    Gemmer, C.3    Kjær, M.4
  • 21
    • 0037101936 scopus 로고    scopus 로고
    • Interleukin-6 production in human subcutaneous abdominal adipose tissue: The effect of exercise
    • Lyngsø D, Simonsen I, and Bulow J. Interleukin-6 production in human subcutaneous abdominal adipose tissue: the effect of exercise. J Physiol 543: 373-378, 2002.
    • (2002) J Physiol , vol.543 , pp. 373-378
    • Lyngsø, D.1    Simonsen, I.2    Bulow, J.3
  • 22
    • 0037101934 scopus 로고    scopus 로고
    • Metabolic effects of interleukin-6 in human splanchnic and adipose tissue
    • Lyngso D, Simonsen L, and Bulow J. Metabolic effects of interleukin-6 in human splanchnic and adipose tissue. J Physiol 543: 379-386, 2002.
    • (2002) J Physiol , vol.543 , pp. 379-386
    • Lyngso, D.1    Simonsen, L.2    Bulow, J.3
  • 23
    • 0032013336 scopus 로고    scopus 로고
    • Interleukin-1 and interleukin-6 mediated skeletal muscle arteriolar vasodilation: In vitro versus in vivo studies
    • Minghini A, Britt LD, and Hill MA. Interleukin-1 and interleukin-6 mediated skeletal muscle arteriolar vasodilation: in vitro versus in vivo studies. Shock 9: 210-215, 1998.
    • (1998) Shock , vol.9 , pp. 210-215
    • Minghini, A.1    Britt, L.D.2    Hill, M.A.3
  • 25
    • 0343526364 scopus 로고    scopus 로고
    • Growth hormone and adipocyte function in obesity
    • Nam SY and Marcus C. Growth hormone and adipocyte function in obesity. Horm Res 53: 87-97, 2000.
    • (2000) Horm Res , vol.53 , pp. 87-97
    • Nam, S.Y.1    Marcus, C.2
  • 28
    • 0033304608 scopus 로고    scopus 로고
    • The differential effect of food intake and beta-adrenergic stimulation on adipose-derived hormones and cytokines in man
    • Orban Z, Remaley AT, Sampson M, Trajanoski Z, and Chrousos GP. The differential effect of food intake and beta-adrenergic stimulation on adipose-derived hormones and cytokines in man. J Clin Endocrinol Metab 84: 2126-2133, 1999.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 2126-2133
    • Orban, Z.1    Remaley, A.T.2    Sampson, M.3    Trajanoski, Z.4    Chrousos, G.P.5
  • 29
    • 0034454649 scopus 로고    scopus 로고
    • Effects of cortisol and growth hormone on lipolysis in human adipose tissue
    • Ottosson M, Lonnroth P, Bjorntorp P, and Eden S. Effects of cortisol and growth hormone on lipolysis in human adipose tissue. J Clin Endocrinol Metab 85: 799-803, 2000.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 799-803
    • Ottosson, M.1    Lonnroth, P.2    Bjorntorp, P.3    Eden, S.4
  • 30
    • 0035886973 scopus 로고    scopus 로고
    • Muscle-derived interleukin-6: Possible biological effects
    • Pedersen BK, Steensberg A, and Schjerling P. Muscle-derived interleukin-6: possible biological effects. J Physiol 536: 329-337, 2001.
    • (2001) J Physiol , vol.536 , pp. 329-337
    • Pedersen, B.K.1    Steensberg, A.2    Schjerling, P.3
  • 31
    • 0026128307 scopus 로고
    • Table of nonprotein respiratory quotient: An update
    • Péronnet F and Massicotte D. Table of nonprotein respiratory quotient: an update. Can J Sport Sci 16: 23-29, 1991.
    • (1991) Can J Sport Sci , vol.16 , pp. 23-29
    • Péronnet, F.1    Massicotte, D.2
  • 32
    • 0034682622 scopus 로고    scopus 로고
    • Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial
    • Sesmilo G, Biller BM, Llevadot J, Hayden D, Hanson G, Rifai N, and Klibanski A. Effects of growth hormone administration on inflammatory and other cardiovascular risk markers in men with growth hormone deficiency. A randomized, controlled clinical trial. Ann Intern Med 133: 111-122, 2000.
    • (2000) Ann Intern Med , vol.133 , pp. 111-122
    • Sesmilo, G.1    Biller, B.M.2    Llevadot, J.3    Hayden, D.4    Hanson, G.5    Rifai, N.6    Klibanski, A.7
  • 33
    • 0035369080 scopus 로고    scopus 로고
    • Carbohydrate attenuates the increase in plasma IL-6, but not in skeletal muscle IL-6 mRNA, during exercise in humans
    • Starkie RL, Arkinstall MJ, Koukoulas I, Hawley JA, and Febbraio MA. Carbohydrate attenuates the increase in plasma IL-6, but not in skeletal muscle IL-6 mRNA, during exercise in humans. J Physiol 533: 585-591, 2001.
    • (2001) J Physiol , vol.533 , pp. 585-591
    • Starkie, R.L.1    Arkinstall, M.J.2    Koukoulas, I.3    Hawley, J.A.4    Febbraio, M.A.5
  • 34
    • 0035006714 scopus 로고    scopus 로고
    • Circulating monocytes are not the source of elevations in plasma IL-6 and TNF-α levels after prolonged running
    • Starkie RL, Rolland J, Angus DJ, Anderson MJ, and Febbraio MA. Circulating monocytes are not the source of elevations in plasma IL-6 and TNF-α levels after prolonged running. Am J Physiol Cell Physiol 280: C769-C774, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Starkie, R.L.1    Rolland, J.2    Angus, D.J.3    Anderson, M.J.4    Febbraio, M.A.5
  • 37
    • 0034668926 scopus 로고    scopus 로고
    • Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6
    • Steensberg A, van Hall G, Osada T, Sacchetti M, Saltin B, and Klarlund Pedersen B. Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 529: 237-242, 2000.
    • (2000) J Physiol , vol.529 , pp. 237-242
    • Steensberg, A.1    Van Hall, G.2    Osada, T.3    Sacchetti, M.4    Saltin, B.5    Klarlund Pedersen, B.6
  • 39
    • 0029823150 scopus 로고    scopus 로고
    • Growth hormone increases interleukin-6 produced by human osteoblast-like cells
    • Swolin D and Ohlsson C. Growth hormone increases interleukin-6 produced by human osteoblast-like cells. J Clin Endocrinol Metab 81: 4329-4333, 1996.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 4329-4333
    • Swolin, D.1    Ohlsson, C.2
  • 40
    • 0030934704 scopus 로고    scopus 로고
    • Regulation of interleukin (IL)-1 alpha, IL-1 beta, and IL-6 expression by growth hormone and prolactin in bovine thymic stromal cells
    • Tseng YH, Kessler MA, and Schuler LA. Regulation of interleukin (IL)-1 alpha, IL-1 beta, and IL-6 expression by growth hormone and prolactin in bovine thymic stromal cells. Mol Cell Endocrinol 128: 117-127, 1997.
    • (1997) Mol Cell Endocrinol , vol.128 , pp. 117-127
    • Tseng, Y.H.1    Kessler, M.A.2    Schuler, L.A.3
  • 41
    • 0037232298 scopus 로고    scopus 로고
    • Nicotinamide is a potent inhibitor of proinflammatory cytokines
    • Ungerstedt JS, Blomback M, and Soderstrom T. Nicotinamide is a potent inhibitor of proinflammatory cytokines. Clin Exp Immunol 131: 48-52, 2003.
    • (2003) Clin Exp Immunol , vol.131 , pp. 48-52
    • Ungerstedt, J.S.1    Blomback, M.2    Soderstrom, T.3
  • 44
    • 0036313811 scopus 로고    scopus 로고
    • Final hormonal regulation of interleukin-6 production in human adipocytes
    • Vicennati V. Final hormonal regulation of interleukin-6 production in human adipocytes. Int J Obes Relat Metab Disord 26: 905-911, 2002.
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 905-911
    • Vicennati, V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.