Genomic organization and expression profile of the human and mouse WAVE gene family

Mammalian Genome

Volumn 14, Issue 5, 2003, Pages 314-322

  Sossey Alaoui, Khalid ^a   Head, Karen ^a   Nowak, Norma ^a   Cowell, John K ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; GENE PRODUCT; PROTEIN WAVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CYTOSKELETON; GENE DUPLICATION; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENE SEQUENCE; HUMAN; MOUSE; MULTIGENE FAMILY; NEUROBLASTOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; SEQUENCE ANALYSIS; SYNTENY;

AMINO ACID SEQUENCE; ANIMALS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 1; CLONING, MOLECULAR; DNA PRIMERS; EXONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INTRONS; MICE; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PHYLOGENY; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION, GENETIC; WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY;

EID: 0037407621     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-002-2247-7     Document Type: Article

References (25)

1. Bauer A, Savelyeva L, Claas A, Praml C, Berthold F et al. (2001) Smallest region of overlapping deletion in lp36 in human neuroblastoma: a 1 Mbp cosmid and PAC contig. Genes Chromosomes Cancer 31, 228-239
2. Benachenhou N, Massy I, Vacher J (2002) Characterization and expression analyses of the mouse Wiskott-Aldrich syndrome protein (WASP) family member Wave1/Scar. Genes 290, 131-140
3. Biesova Z, Piccoli C, Wong WT (1997) Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth. Oncogene 14, 233-241
4. Carlier MF, Nioche P, Broutin-L'Hermite I, Boujemaa R, Le Clainche C et al. (2000) GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex. J Biol Chem 275, 21946-21952
5. Cooper MD, Chae HP, Lowman JT, Krivit W, Good RA (1968) Wiskott-Aldrich syndrome: an immunologic deficiency disease involving the afferent limb of immunity. Am J Med 44, 499-513
6. DeBry RW, Seldin MF (1996) Human/mouse homology relationships. Genomics 33, 337-351
7. Derry JMJ, Ochs HD, Francke U (1994) Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 78, 635-644
8. Fukuoka M, Suetsugu S, Miki H, Fukami K, Endo T et al. (2001) A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42. J Cell Biol 152, 471-482
9. Krugmann S, Jordens I, Gevaert K, Driessens M, Vandekerckhove J et al. (2001) Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex. Curr Biol 11, 1645-1655
10. MacCarthy-Morrogh L, Gaspar HB, Wang YC, Katz F, Thompson L et al. (1998) Absence of expression of the Wiskott-Aldrich syndrome protein in peripheral blood cells of Wiskott-Aldrich syndrome patients. Clin Immunol Immunopathol 88, 22-27
11. Maris JM, Guo C, Blake D, White PS, Hogarty MB et al. (2001) Comprehensive analysis of chromosome 1p deletions in neuroblastoma. Med Pediatr Oncol 36, 32-36
12. Meyer GE, Shelden E, Kim B, Feldman EL (2001) Insulin-like growth factor I stimulates motility in human neuroblastoma cells. Oncogene 20, 7542-7550
13. Michalski AJ, Cotter FE, Cowell JK (1992) Isolation of chromosome-specific DNA sequences from an Alu polymerase chain reaction library to define the breakpoint in a patient with a constitutional translocation t(1;13) (q22;q12) and ganglioneuroblastoma. Oncogene 7, 1595-1602
14. Miki H, Suetsugu S, Takenawa T (1998) WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J 17, 6932-6941
15. Miki H, Takenawa T (2002) WAVE2 serves a functional partner of IRSp53 by regulating its interaction with Rac. Biochem Biophys Res Commun 293, 93-99
16. Miki H, Yamaguchi H, Suetsugu S, Takenawa T (2000) IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. Nature 408, 732-735
17. Mitchison TJ, Cramer LP (1996) Actin-based cell motility and cell locomotion. Cell 84, 371-379
18. Nagase T, Seki N, Ishikawa K, Orira M, Kawarabayasi Y et al. (1996) Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. DNA Res 3, 321-329, 341-354
19. Oda K, Shiratsuchi T, Nishimori H, Inazawa J, Yoshikawa H et al. (1999) Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1. Cytogenet Cell Genet 84, 75-82
20. Okamura-Oho Y, Miyashita T, Ohmi K, Yamada M (1999) Dentatorubral-pallidoluysian atrophy protein interacts through a proline-rich region near polyglutamine with the SH3 domain of an insulin receptor tyrosine kinase substrate. Hum Mol Genet 8, 947-957
21. Rohatgi R, Nollau P, Ho Hy H, Kirschner MW, Mayer BJ (2001) Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway. J Biol Chem 276, 26448-26452
22. Sossey-Alaoui K, Su G, Malaj E, Roe B, Cowell JK (2002) WAVE3, an actin-polymerization gene, is truncated and inactivated as a result of a constitutional t(1;13)(q21;q12) chromosome translocation in a patient with ganglioneuroblastoma. Oncogene 21, 5967-5974
23. Spitz R, Hero B, Westermann F, Ernestus K, Schwab M et al. (2002) Fluorescence in situ hybridization analyses of chromosome band 1p36 in neuroblastoma detect two classes of alterations. Genes Chromosomes Cancer 34, 299-305
24. Suetsugu S, Miki H, Takenawa T (1999) Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex. Biochem Biophys Res Commun 260, 296-302
25. Takenawa T, Miki H (2001) WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement. J Cell Sci 114, 1801-1809