-
1
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smith AM and Bos JL: Genetic alterations during colorectal-tumor development. New Engl J Med 319: 525-532, 1988.
-
(1988)
New Engl J Med
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
Kern, S.E.4
Preisinger, A.C.5
Leppert, M.6
Nakamura, Y.7
White, R.8
Smith, A.M.9
Bos, J.L.10
-
2
-
-
0025312728
-
A Genetic model for colorectal tumorgenesis
-
Fearon ER and Vogelstein B: A Genetic model for colorectal tumorgenesis. Cell 61: 759-767, 1990.
-
(1990)
Cell
, vol.61
, pp. 759-767
-
-
Fearon, E.R.1
Vogelstein, B.2
-
3
-
-
0026452949
-
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
-
Hartwell L: Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell 71: 543-546, 1992.
-
(1992)
Cell
, vol.71
, pp. 543-546
-
-
Hartwell, L.1
-
4
-
-
0032546360
-
Mutations of mitotic check point genes in human cancer
-
Cahill DP and Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD, Kinzler KW and Vogelstein B: Mutations of mitotic check point genes in human cancer. Nature 392: 300-303, 1998.
-
(1998)
Nature
, vol.392
, pp. 300-303
-
-
Cahill, D.P.1
Lengauer, C.2
Yu, J.3
Riggins, G.J.4
Willson, J.K.5
Markowitz, S.D.6
Kinzler, K.W.7
Vogelstein, B.8
-
5
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG: Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68: 820-823, 1971.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
6
-
-
0027145633
-
Mutations of mutS homolog in hereditary nonpolyposis colorectal cancer
-
Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R, Peltomaki P, Sistonen P, Aaltonen LA, Lahti MN, Guan XY, Zhang J, Meltzer PS, Yu JW, Kao FT, Chen DJ, Cerosaletti KM, Fournier REK, Todd S, Lewis T, Leach RJ, Naylor SL, Weissenbach J, Mecklin JP, Jarvinen H, Petersen GM, Hamilton SR, Green J, Jass J, Watson P, Lynch HT, Trent JM, Chapelle A, Kinzler KW and Vogelstein B: Mutations of mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75: 1215-1225, 1993.
-
(1993)
Cell
, vol.75
, pp. 1215-1225
-
-
Leach, F.S.1
Nicolaides, N.C.2
Papadopoulos, N.3
Liu, B.4
Jen, J.5
Parsons, R.6
Peltomaki, P.7
Sistonen, P.8
Aaltonen, L.A.9
Lahti, M.N.10
Guan, X.Y.11
Zhang, J.12
Meltzer, P.S.13
Yu, J.W.14
Kao, F.T.15
Chen, D.J.16
Cerosaletti, K.M.17
Fournier, R.E.K.18
Todd, S.19
Lewis, T.20
Leach, R.J.21
Naylor, S.L.22
Weissenbach, J.23
Mecklin, J.P.24
Jarvinen, H.25
Petersen, G.M.26
Hamilton, S.R.27
Green, J.28
Jass, J.29
Watson, P.30
Lynch, H.T.31
Trent, J.M.32
Chapelle, A.33
Kinzler, K.W.34
Vogelstein, B.35
more..
-
7
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW and Vogelstein B: Lessons from hereditary colorectal cancer. Cell 87: 159-170, 1996.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
8
-
-
0033946039
-
DNA missmatch repair genes and colorectal cancer
-
Wheeler JMD: DNA missmatch repair genes and colorectal cancer. Gut 47: 148-153, 2000.
-
(2000)
Gut
, vol.47
, pp. 148-153
-
-
Wheeler, J.M.D.1
-
9
-
-
0027314411
-
Microsatellite instability in cancer of the proximal colon
-
Thibodeau SN, Bren G and Schaid D: Microsatellite instability in cancer of the proximal colon. Science 260: 816-819, 1993.
-
(1993)
Science
, vol.260
, pp. 816-819
-
-
Thibodeau, S.N.1
Bren, G.2
Schaid, D.3
-
10
-
-
0027136828
-
Genetic instability in colorectal cancer: Relationship to clinicopathological variables and family history
-
Lothe RA, Peltomaki P, Meling GI, Aaltonen LA, Lahti MN, Pylkkanen L, Heimdal K, Anderson TI, Moller P, Rognum TO, Fossa SD, Haldorson T, Langmark F, Brogger A, Chapelle A and Borresen AL: Genetic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res 53: 5849-5852, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 5849-5852
-
-
Lothe, R.A.1
Peltomaki, P.2
Meling, G.I.3
Aaltonen, L.A.4
Lahti, M.N.5
Pylkkanen, L.6
Heimdal, K.7
Anderson, T.I.8
Moller, P.9
Rognum, T.O.10
Fossa, S.D.11
Haldorson, T.12
Langmark, F.13
Brogger, A.14
Chapelle, A.15
Borresen, A.L.16
-
11
-
-
0028276666
-
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
-
Kim H, Jin J, Vogelstein B and Hamilton SR: Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol 145: 148-156, 1994.
-
(1994)
Am J Pathol
, vol.145
, pp. 148-156
-
-
Kim, H.1
Jin, J.2
Vogelstein, B.3
Hamilton, S.R.4
-
12
-
-
0028867561
-
Microsatellite instability in human colonic cancer is not a useful clinical indicator of familial colorectal cancer
-
Samowitz WS, Slattery ML and Kerber RA: Microsatellite instability in human colonic cancer is not a useful clinical indicator of familial colorectal cancer. Gastroenterology 109: 1765-1771, 1995.
-
(1995)
Gastroenterology
, vol.109
, pp. 1765-1771
-
-
Samowitz, W.S.1
Slattery, M.L.2
Kerber, R.A.3
-
13
-
-
0030054532
-
Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer
-
Konishi M, Yonoshita RK, Tanaka K, Muraoka M, Onda A, Okumura Y, Kishi N, Iwama T, Mori T, Koike M, Ushio K, Chiba M, Nomizu S, Konishi F, Utsunomiya J and Miyaki M: Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer. Gastroenterology 111: 307-17, 1996.
-
(1996)
Gastroenterology
, vol.111
, pp. 307-317
-
-
Konishi, M.1
Yonoshita, R.K.2
Tanaka, K.3
Muraoka, M.4
Onda, A.5
Okumura, Y.6
Kishi, N.7
Iwama, T.8
Mori, T.9
Koike, M.10
Ushio, K.11
Chiba, M.12
Nomizu, S.13
Konishi, F.14
Utsunomiya, J.15
Miyaki, M.16
-
14
-
-
7144256236
-
Morphology of sporadic colorectal cancer with DNA replication errors
-
Jass JR, Do KA, Simms LA, Iino H, Wynter C, Pillay SP, Searle J, Smith GR, Young G and Leggett B: Morphology of sporadic colorectal cancer with DNA replication errors. Gut 42: 673-679, 1998.
-
(1998)
Gut
, vol.42
, pp. 673-679
-
-
Jass, J.R.1
Do, K.A.2
Simms, L.A.3
Iino, H.4
Wynter, C.5
Pillay, S.P.6
Searle, J.7
Smith, G.R.8
Young, G.9
Leggett, B.10
-
15
-
-
0033043642
-
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways
-
Jass JR, Biden KG, Cummings MC, Simms LA, Walsh M, Schoch E, Meltzer SJ, Wright C, Searle J, Young J and Leggett BA: Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. J Clin Pathol 52: 455-460, 1999.
-
(1999)
J Clin Pathol
, vol.52
, pp. 455-460
-
-
Jass, J.R.1
Biden, K.G.2
Cummings, M.C.3
Simms, L.A.4
Walsh, M.5
Schoch, E.6
Meltzer, S.J.7
Wright, C.8
Searle, J.9
Young, J.10
Leggett, B.A.11
-
17
-
-
0036174195
-
Comparison of clinicopathologic characteristics and genetic alterations between microsatellite instability-positive and microsatellite instability-negative sporadic colorectal carcinomas in patients younger than 40 years old
-
Suh JH, Lim SD, Kim JC, Hong SH and Kang GH: Comparison of clinicopathologic characteristics and genetic alterations between microsatellite instability-positive and microsatellite instability-negative sporadic colorectal carcinomas in patients younger than 40 years old. Dis Colon Rectum 45: 219-228, 2002.
-
(2002)
Dis Colon Rectum
, vol.45
, pp. 219-228
-
-
Suh, J.H.1
Lim, S.D.2
Kim, J.C.3
Hong, S.H.4
Kang, G.H.5
-
18
-
-
0032534069
-
A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development 9f international criteria for the determination of microsatellite instability in colorectal cancer
-
Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Bigas MAR, Fodde G, Ranzani N and Srivastava S: A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: development 9f international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 5248-5257
-
-
Boland, C.R.1
Thibodeau, S.N.2
Hamilton, S.R.3
Sidransky, D.4
Eshleman, J.R.5
Burt, R.W.6
Meltzer, S.J.7
Bigas, M.A.R.8
Fodde, G.9
Ranzani, N.10
Srivastava, S.11
-
19
-
-
0025848680
-
The international collaborative group on hereditary non-polyposis colorectal cancer (ICG-HNPCC)
-
Vason HF, Mecklin JP, Khan PM and Lynch HT: The international collaborative group on hereditary non-polyposis colorectal cancer (ICG-HNPCC). Dis Colon Rectum 34: 424-425, 1991.
-
(1991)
Dis Colon Rectum
, vol.34
, pp. 424-425
-
-
Vason, H.F.1
Mecklin, J.P.2
Khan, P.M.3
Lynch, H.T.4
-
20
-
-
0017148259
-
A genetic method for isolation of high molecular weight DNA from eukaryotes
-
Blin N and Stafford DW: A genetic method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res 3: 2303-2308, 1976.
-
(1976)
Nucleic Acids Res
, vol.3
, pp. 2303-2308
-
-
Blin, N.1
Stafford, D.W.2
-
21
-
-
0024595101
-
Detection of polymorphism of human DNA by gel electrophoresis as single-strand conformation polymorphisms
-
Orita M, Iwahana H, Kanazawa H, Hayashi K and Sekiya T: Detection of polymorphism of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 86: 2766-2770, 1989.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2766-2770
-
-
Orita, M.1
Iwahana, H.2
Kanazawa, H.3
Hayashi, K.4
Sekiya, T.5
-
22
-
-
0029624371
-
p53 mutations and overexpressions in Japanese breast cancer
-
Fukushima T, Onda M, Abe R, Otake T, Kimijima I and Tsuchiya A: p53 mutations and overexpressions in Japanese breast cancer. Eur J Surg Oncol 21: 595-600, 1995.
-
(1995)
Eur J Surg Oncol
, vol.21
, pp. 595-600
-
-
Fukushima, T.1
Onda, M.2
Abe, R.3
Otake, T.4
Kimijima, I.5
Tsuchiya, A.6
-
23
-
-
0031595677
-
The EnVision™ + system: A new immunohistochemical method for diagnostics and research. Critical comparison with the APAAP, ChemMate™. CSA, LABC, and SABC techniques
-
Sabattini E, Bisgaard K, Ascani S, Poggi S, Piccioli M, Ceccarelli C, Pieri F, Orcioni GF and Pileri SA: The EnVision™ + system: a new immunohistochemical method for diagnostics and research. Critical comparison with the APAAP, ChemMate™. CSA, LABC, and SABC techniques. J Clin Pathol 51: 506-511, 1998.
-
(1998)
J Clin Pathol
, vol.51
, pp. 506-511
-
-
Sabattini, E.1
Bisgaard, K.2
Ascani, S.3
Poggi, S.4
Piccioli, M.5
Ceccarelli, C.6
Pieri, F.7
Orcioni, G.F.8
Pileri, S.A.9
-
24
-
-
0030778613
-
Diagnostic microsatellite instability: Definition and correlation with mismatch repair protein expression
-
Dietmaier W, Wallinger S, Bocker T, Kullmann F, Fishel R and Ruschoff J: Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res 57: 4749-4756, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 4749-4756
-
-
Dietmaier, W.1
Wallinger, S.2
Bocker, T.3
Kullmann, F.4
Fishel, R.5
Ruschoff, J.6
-
25
-
-
0035181352
-
Microsatellite instability in thyroid cancer: Hot spot, clinicopathological implications, and prognostic significance
-
Onda M, Nakamura I, Suzuki S, Takenoshita S, Brogren CH, Stampanoni S, Li D and Rampino N: Microsatellite instability in thyroid cancer: hot spot, clinicopathological implications, and prognostic significance. Clin Cancer Res 7: 3444-3449, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3444-3449
-
-
Onda, M.1
Nakamura, I.2
Suzuki, S.3
Takenoshita, S.4
Brogren, C.H.5
Stampanoni, S.6
Li, D.7
Rampino, N.8
-
26
-
-
0000620016
-
Molecular biology of colorectal cancer: A clinician's view
-
Allen JI: Molecular biology of colorectal cancer: a clinician's view. Perspect Colon Rectal Surg 8: 181-202, 1995.
-
(1995)
Perspect Colon Rectal Surg
, vol.8
, pp. 181-202
-
-
Allen, J.I.1
-
27
-
-
0031710654
-
Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespred instability in microsatellite sequences
-
Fujiwara T, Stolker JM, Watanabe T, Rashid A, Longo P, Eshleman JR, Booker S, Lynch HT, Jass JR, Green JS, Kim H, Jen J, Vogelstein B and Hamilton SR: Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespred instability in microsatellite sequences. Am J Pathol 153: 1063-1078, 1998.
-
(1998)
Am J Pathol
, vol.153
, pp. 1063-1078
-
-
Fujiwara, T.1
Stolker, J.M.2
Watanabe, T.3
Rashid, A.4
Longo, P.5
Eshleman, J.R.6
Booker, S.7
Lynch, H.T.8
Jass, J.R.9
Green, J.S.10
Kim, H.11
Jen, J.12
Vogelstein, B.13
Hamilton, S.R.14
-
28
-
-
0035070638
-
Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer
-
Samowitz WS, Holden JA, Curtin K, Edwards SL, Walker AR, Lin HA, Robertson MA, Nichols MF, Gruenthal KM, Lynch BJ, Leppert MF and Slattery ML: Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancer. Am J Pathol 158: 1517-1524, 2001.
-
(2001)
Am J Pathol
, vol.158
, pp. 1517-1524
-
-
Samowitz, W.S.1
Holden, J.A.2
Curtin, K.3
Edwards, S.L.4
Walker, A.R.5
Lin, H.A.6
Robertson, M.A.7
Nichols, M.F.8
Gruenthal, K.M.9
Lynch, B.J.10
Leppert, M.F.11
Slattery, M.L.12
-
29
-
-
0034997971
-
Microsatellite instability and the clinicopathological feature of sporadic colorectal cancer
-
Ward R, Meagher A, Tomlinson I, O'Conner T, Norrie M, Wu R and Howkins N: Microsatellite instability and the clinicopathological feature of sporadic colorectal cancer. Gut 48: 821-829, 2001.
-
(2001)
Gut
, vol.48
, pp. 821-829
-
-
Ward, R.1
Meagher, A.2
Tomlinson, I.3
O'Conner, T.4
Norrie, M.5
Wu, R.6
Howkins, N.7
-
30
-
-
0034895979
-
P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma
-
Elsaleh H, Powell B, McCaul K, Grien F, Grant R, Joseph D and Iacopetta B: P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin Cancer Res 7: 1343-1349, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1343-1349
-
-
Elsaleh, H.1
Powell, B.2
McCaul, K.3
Grien, F.4
Grant, R.5
Joseph, D.6
Iacopetta, B.7
-
31
-
-
0036183810
-
Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer
-
Gervaz P, Cerottini JP, Bouzourene H, Hahnloser D, Doan CL, Benhatter J, Chaubert P, Secic M, Gillet M and Carethers JM: Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3N0 colorectal cancer. Surgery 131: 190-197, 2002.
-
(2002)
Surgery
, vol.131
, pp. 190-197
-
-
Gervaz, P.1
Cerottini, J.P.2
Bouzourene, H.3
Hahnloser, D.4
Doan, C.L.5
Benhatter, J.6
Chaubert, P.7
Secic, M.8
Gillet, M.9
Carethers, J.M.10
-
32
-
-
12644274663
-
Alternative genetic pathways in colorectal carcinoma
-
Olschwang S, Hamelin R, Puig PL, Thuille B, Rycke YD, Li YJ, Muzeau F, Girodet J, Salmon RJ and Thomas G: Alternative genetic pathways in colorectal carcinoma. Proc Natl Acad Sci USA 94: 12122-12127, 1997.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12122-12127
-
-
Olschwang, S.1
Hamelin, R.2
Puig, P.L.3
Thuille, B.4
Rycke, Y.D.5
Li, Y.J.6
Muzeau, F.7
Girodet, J.8
Salmon, R.J.9
Thomas, G.10
-
33
-
-
0033778251
-
Pathogenesis of non-familial colorectal carcinomas with high microsatellite instability
-
Shitoh K, Konishi F, Miyaki M, Iijima T, Furukawa T, Tsukamoto T and Nagai H: Pathogenesis of non-familial colorectal carcinomas with high microsatellite instability. J Clin Pathol 53: 841-845, 2000.
-
(2000)
J Clin Pathol
, vol.53
, pp. 841-845
-
-
Shitoh, K.1
Konishi, F.2
Miyaki, M.3
Iijima, T.4
Furukawa, T.5
Tsukamoto, T.6
Nagai, H.7
-
34
-
-
0036605096
-
Prognostic significance of p53 mutations in colon cancer at the population level
-
Samowitz WS, Curtin K, Ma KN, Edwards S, Schaffer D, Leppert MF and Slattery ML: Prognostic significance of p53 mutations in colon cancer at the population level. Int J Cancer 99: 597-602, 2002.
-
(2002)
Int J Cancer
, vol.99
, pp. 597-602
-
-
Samowitz, W.S.1
Curtin, K.2
Ma, K.N.3
Edwards, S.4
Schaffer, D.5
Leppert, M.F.6
Slattery, M.L.7
-
35
-
-
0032522658
-
Microsatellite instability in colorectal cancer, different mutator phenotypes and the principal involvement of hMLH1
-
Thibodeau SN, French AJF, Cunningham JM, Tester D, Burgart LJ, Roche PC, McDonnell SK, Schaid DJ, Vockley CW, Michels VV, Farr GH and O'Connell MJ: Microsatellite instability in colorectal cancer, different mutator phenotypes and the principal involvement of hMLH1. Cancer Res 58: 1713-1718, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 1713-1718
-
-
Thibodeau, S.N.1
French, A.J.F.2
Cunningham, J.M.3
Tester, D.4
Burgart, L.J.5
Roche, P.C.6
McDonnell, S.K.7
Schaid, D.J.8
Vockley, C.W.9
Michels, V.V.10
Farr, G.H.11
O'Connell, M.J.12
-
36
-
-
0036144385
-
Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait
-
Halford S, Sasieni P, Rowan A, Wasan H, Bodmer W, Talbot I, Hawkins N, Ward R and Tomlinson I: Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait. Cancer Res 62: 53-57, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 53-57
-
-
Halford, S.1
Sasieni, P.2
Rowan, A.3
Wasan, H.4
Bodmer, W.5
Talbot, I.6
Hawkins, N.7
Ward, R.8
Tomlinson, I.9
-
37
-
-
0036234167
-
Does MSI-low exist?
-
Tomlinson I, Halford S, Aaltonen L, Hawkins N and Ward R: Does MSI-low exist? J Pathol 197: 6-13, 2002.
-
(2002)
J Pathol
, vol.197
, pp. 6-13
-
-
Tomlinson, I.1
Halford, S.2
Aaltonen, L.3
Hawkins, N.4
Ward, R.5
|