Preparation of theophylline-hydroxypropylmethylcellulose matrices using supercritical antisolvent precipitation: A preliminary study

Drug Development and Industrial Pharmacy

Volumn 32, Issue 1, 2006, Pages 39-52

  Moneghini, M ^a   Perissutti, B ^a   Kikic, I ^b   Grassi, M ^b   Cortesi, A ^b   Princivalle, F ^c  

^a UNIVERSITY OF TRIESTE   (Italy)

^b Department of Chemical Environmental and Raw Materials Engineering   (Italy)

^c Department of Earth Sciences ^*  (Italy)

Author keywords

Hydroxypropylmethylcellulose; Modeling; Physicochemical characterization; Supercritical antisolvent technique; Theophylline

Indexed keywords

DRUG CARRIER; HYDROXYPROPYLMETHYLCELLULOSE; POLYMER; THEOPHYLLINE;

ARTICLE; CHEMICAL PROCEDURES; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; DRUG SYNTHESIS; IN VITRO STUDY; MATHEMATICAL MODEL; PH; PHYSICAL CHEMISTRY; PRECIPITATION; SOLID STATE; SUPERCRITICAL ANTISOLVENT PRECIPITATION; SUPERCRITICAL FLUID; SUSTAINED DRUG RELEASE; TABLET; TABLET COMPRESSION; X RAY DIFFRACTION;

CALORIMETRY, DIFFERENTIAL SCANNING; METHYLCELLULOSE; MODELS, THEORETICAL; PRECIPITATION; SOLUBILITY; TABLETS; TECHNOLOGY, PHARMACEUTICAL; THEOPHYLLINE; X-RAY DIFFRACTION;

EID: 32344452575     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040500388037     Document Type: Article

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