Marinomycins A-D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus "Marinispora"

Journal of the American Chemical Society

Volumn 128, Issue 5, 2006, Pages 1622-1632

  Kwon, Hak Cheol ^a   Kauffman, Christopher A ^a   Jensen, Paul R ^a   Fenical, William ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACIDS; CELLS; ISOMERIZATION; MARINE BIOLOGY; PATHOLOGY; TUMORS;

MACRODIOLIDES; MARINE ACTINOMYCETE; MARINOMYCINS A-D; TETRAENE-PENTAHYDROXY POLYKETIDE CHAINS;

ANTIBIOTICS;

ANTINEOPLASTIC ANTIBIOTIC; BENZOIC ACID; DIMER; LACTONE; MARINOMYCIN A; MARINOMYCIN B; MARINOMYCIN C; MARINOMYCIN D; POLYKETIDE; UNCLASSIFIED DRUG;

ACTINOBACTERIA; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; CANCER CELL CULTURE; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG ISOLATION; DRUG STRUCTURE; GENUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOMER; ISOMERIZATION; LEUKEMIA CELL LINE; MARINISPORA; MELANOMA CELL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; VANCOMYCIN RESISTANT ENTEROCOCCUS;

ACTINOBACTERIA; ALKENES; ANTI-BACTERIAL AGENTS; ANTIBIOTICS, ANTINEOPLASTIC; CANDIDA ALBICANS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; ENTEROCOCCUS FAECIUM; HUMANS; LACTONES; MACROLIDES; MELANOMA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; STAPHYLOCOCCUS AUREUS;

EID: 32244440458     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0558948     Document Type: Article

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