PLA2 inhibitory activity of marine sesterterpenoids cladocorans, their diastereomers and analogues

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 2, 2006, Pages 268-270

  Miyaoka, Hiroaki ^a   Yamanishi, Makoto ^a   Mitome, Hidemichi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Analogue; Cladocoran; Inhibitor; Manoalide; Secretory phospholipase A2 (sPLA2)

Indexed keywords

15 EPI 18 EPICLADOCORAN A; 15 EPI 18 EPICLADOCORAN B; 15 EPICLADOCORAN A; 15 EPICLADOCORAN B; 18 EPICLADOCORAN A; 18 EPICLADOCORAN B; CLADOCORAN A; CLADOCORAN B; MANOALIDE; PHOSPHOLIPASE A2 INHIBITOR; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG; BEE VENOM; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; DYSIDIOLIDE; GAMMA BUTYROLACTONE; PHOSPHODIESTERASE INHIBITOR; PHOSPHOLIPASE A; TERPENE;

ARTICLE; DIASTEREOISOMER; DRUG ACTIVITY; DRUG ISOLATION; ENZYME INHIBITION; IC 50; ANIMAL; ANTHOZOA; BEE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOISOMERISM;

4-BUTYROLACTONE; ANIMALS; ANTHOZOA; BEE VENOMS; BEES; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASES A; STEREOISOMERISM; TERPENES;

EID: 32044452714     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.268     Document Type: Article

References (16)

1. Blunt J. W., Copp B. R., Munro M. H. G., Northcote P. T., Prinsep M. R., Nat. Prod. Rep., 22, 15-61 (2005) and preceding reviews in the series.
2. de Silva E. D., Scheuer P. J., Tetrahedron Lett., 21, 1611-1614 (1980).
3. De Rosa S., Crispino A., De Giulio A., Iodice C., Pronzato R., Zavodnik N., J. Nat. Prod., 58, 1776-1780 (1995).
4. Cheung A. K., Murelli R., Snapper M. L., J. Org. Chem., 69, 5712-5719 (2004) and references cited therein.
5. De Rosa M., Giordano S., Scettri A., Sodano G., Soriente A., Pastor P. G., Alcaraz M. J., Paya M., J. Med. Chem., 41, 3232-3238 (1998).
6. Gunasekera S. P., McCarthy P. J., Kelly-Borges M., Lobkovsky E., Clardy J., J. Am. Chem. Soc., 118, 8759-8760 (1996).
7. Fontana A., Ciavatta M. L., Cimino G., J. Org. Chem., 63, 2845-2849 (1998).
8. Miyaoka H., Kajiwara Y., Yamada Y., Tetrahedron Lett., 41, 911-914 (2000).
9. Miyaoka H., Kajiwara Y., Hara Y., Yamada Y., J. Org. Chem., 66, 1429-1435 (2001).
10. Miyaoka H., Yamanishi M., Kajiwara Y., Yamada Y., J. Org. Chem., 68, 3476-3479 (2003).
11. Stratakis M., Nencka R., Rabalakos C., Adam W., Krebs O., J. Org. Chem., 67, 8758-8763 (2002).
12. Luly J. R., Dellaria J. F., Plattner J. J., Soderquist J. L., Yi N., J. Org. Chem., 52, 1487-1492 (1987).
13. Commercially available compound.
14. Donkor I. O., Li H., Queener S. F., Eur. J. Med. Chem., 38, 605-611 (2003).
15. Kernan M. R., Faulkner D. J., J. Org. Chem., 53, 2773-2776 (1988).
16. Xie W., Peng H., Kim D.-I., Kunkel M., Powis G., Zalkow L. H., Bioorg. Med. Chem., 9, 1073-1083 (2001).