Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline

Journal of Medicinal Chemistry

Volumn 43, Issue 25, 2000, Pages 4868-4876

  Gu, X H ^a   Yu, H ^a   Jacobson, A E ^a   Rothman, R B ^b   Dersch, C M ^b   George, C ^c   Flippen Anderson, J L ^c   Rice, K C ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b NIDA Addiction Research Center   (United States)

^c NAVAL RESEARCH LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[3 (3,4 DICHLOROPHENYL) 4 METHOXYINDAN 1 YL]METHYLAMINE; DOPAMINE; INDATRALINE; MONOAMINE; NORADRENALIN; SEROTONIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG ABUSE; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; BINDING, COMPETITIVE; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DRUG DESIGN; INDANS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METHYLAMINES; NERVE TISSUE PROTEINS; NEUROTRANSMITTER UPTAKE INHIBITORS; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RADIOLIGAND ASSAY; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS;

EID: 0034649657     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000329v     Document Type: Article

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