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Volumn 45, Issue 2, 2006, Pages 182-190

The glycine 90 to aspartate alteration in the Aβ subunit of PP2A (PPP2R1B) associates with breast cancer and causes a deficit in protein function

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; GENOMIC DNA; GLYCINE; PHOSPHOPROTEIN PHOSPHATASE 2A;

EID: 31944435622     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20284     Document Type: Article
Times cited : (37)

References (35)
  • 1
    • 0029915709 scopus 로고    scopus 로고
    • Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle
    • Ahmadian-Tehrani M, Mumby MC, Kamibayashi C. 1996. Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle. J Biol Chem 271:5164-5170.
    • (1996) J Biol Chem , vol.271 , pp. 5164-5170
    • Ahmadian-Tehrani, M.1    Mumby, M.C.2    Kamibayashi, C.3
  • 4
    • 0033523983 scopus 로고    scopus 로고
    • Absence of PPP2R1B gene alterations in primary ovarian cancers
    • Campbell IG, Manolitsas T. 1999. Absence of PPP2R1B gene alterations in primary ovarian cancers. Oncogene 18:6367-6369.
    • (1999) Oncogene , vol.18 , pp. 6367-6369
    • Campbell, I.G.1    Manolitsas, T.2
  • 6
    • 0031870959 scopus 로고    scopus 로고
    • Pten is essential for embryonic development and tumour suppression
    • Di Cristofano A, Pesce B, Cordon-Cardo C, Pandolfi PP. 1998. Pten . is essential for embryonic development and tumour suppression. Nat Genet 19:348-355.
    • (1998) Nat Genet , vol.19 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3    Pandolfi, P.P.4
  • 7
    • 0033602176 scopus 로고    scopus 로고
    • Refinement of the LOH region 1 at 11q23.1 deleted in human breast carcinomas and sublocalization of 11 expressed sequence tags within the refined region
    • di Iasio MG, Calin G, Tibiletti MG, Vorechovsky I, Benediktsson KP, Taramelli R, Barbanti-Brodano G, Negrini M. 1999. Refinement of the LOH region 1 at 11q23.1 deleted in human breast carcinomas and sublocalization of 11 expressed sequence tags within the refined region. Oncogene 18:1635-1638.
    • (1999) Oncogene , vol.18 , pp. 1635-1638
    • Di Iasio, M.G.1    Calin, G.2    Tibiletti, M.G.3    Vorechovsky, I.4    Benediktsson, K.P.5    Taramelli, R.6    Barbanti-Brodano, G.7    Negrini, M.8
  • 8
    • 0033534405 scopus 로고    scopus 로고
    • The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs
    • Groves MR, Hanlon N, Turowski P, Hemmings BA, Barford D. 1999. The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs. Cell 96:99-110.
    • (1999) Cell , vol.96 , pp. 99-110
    • Groves, M.R.1    Hanlon, N.2    Turowski, P.3    Hemmings, B.A.4    Barford, D.5
  • 11
    • 0027279893 scopus 로고
    • Structure and expression of a 72-kDa regulator subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing
    • Hendrix P, Mayer-Jaekel RE, Cron P, Goris J, Hofsteenge J, Merlevede W, Hemmings BA. 1993. Structure and expression of a 72-kDa regulator subunit of protein phosphatase 2A. Evidence for different size forms produced by alternative splicing. J Biol Chem 268:15267-15276.
    • (1993) J Biol Chem , vol.268 , pp. 15267-15276
    • Hendrix, P.1    Mayer-Jaekel, R.E.2    Cron, P.3    Goris, J.4    Hofsteenge, J.5    Merlevede, W.6    Hemmings, B.A.7
  • 12
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens V, Goris J. 2001. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem J 353:417-439.
    • (2001) Biochem J , vol.353 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 14
    • 0028021165 scopus 로고
    • Comparison of heterotrimeric protein phosphatase 2A containing different B subunits
    • Kamibayashi C, Estes R, Lickteig RL, Yang S-I, Craft C, Mumby MC. 1994. Comparison of heterotrimeric protein phosphatase 2A containing different B subunits. J Biol Chem 269:20139-20148.
    • (1994) J Biol Chem , vol.269 , pp. 20139-20148
    • Kamibayashi, C.1    Estes, R.2    Lickteig, R.L.3    Yang, S.-I.4    Craft, C.5    Mumby, M.C.6
  • 16
    • 0031037772 scopus 로고    scopus 로고
    • Allelic deletions at chromosome 11q22-q23.1 and 11q25-qterm are frequent in sporadic breast but not colorectal cancers
    • Koreth J, Bakkenist CJ, McGee JO. 1997. Allelic deletions at chromosome 11q22-q23.1 and 11q25-qterm are frequent in sporadic breast but not colorectal cancers. Oncogene 14:431-437.
    • (1997) Oncogene , vol.14 , pp. 431-437
    • Koreth, J.1    Bakkenist, C.J.2    McGee, J.O.3
  • 18
    • 0028832251 scopus 로고
    • Identification of a new family of protein phosphatase 2A regulatory subunits
    • McCright B, Virshup DM. 1995. Identification of a new family of protein phosphatase 2A regulatory subunits. J Biol Chem 270: 26123-26128.
    • (1995) J Biol Chem , vol.270 , pp. 26123-26128
    • McCright, B.1    Virshup, D.M.2
  • 19
    • 0031467667 scopus 로고    scopus 로고
    • Molecular cloning and characterization of LOH11CR2A, a new gene within a refined minimal region of LOH at 11q23
    • Monaco C, Negrini M, Sozzi G, Veronese ML, Vorechovsky I, Godwin AK, Croce CM. 1997. Molecular cloning and characterization of LOH11CR2A, a new gene within a refined minimal region of LOH at 11q23. Genomics 46:217-222.
    • (1997) Genomics , vol.46 , pp. 217-222
    • Monaco, C.1    Negrini, M.2    Sozzi, G.3    Veronese, M.L.4    Vorechovsky, I.5    Godwin, A.K.6    Croce, C.M.7
  • 22
    • 0029124902 scopus 로고
    • Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: Identification of three independent regions
    • Rasio D, Negrini M, Manenti G, Dragani TA, Croce CM. 1995. Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: identification of three independent regions. Cancer Res 55:3988-3991.
    • (1995) Cancer Res , vol.55 , pp. 3988-3991
    • Rasio, D.1    Negrini, M.2    Manenti, G.3    Dragani, T.A.4    Croce, C.M.5
  • 23
    • 0032889238 scopus 로고    scopus 로고
    • Binding specificity of protein phosphatase 2A core enzyme for regulatory B subunits and T antigens
    • Ruediger R, Fields K, Walter G. 1999. Binding specificity of protein phosphatase 2A core enzyme for regulatory B subunits and T antigens. J Virol 73:839-842.
    • (1999) J Virol , vol.73 , pp. 839-842
    • Ruediger, R.1    Fields, K.2    Walter, G.3
  • 24
    • 0028082299 scopus 로고
    • Molecular model of the a subunit of protein phosphatase 2A: Interaction with other subunits and tumor antigens
    • Ruediger R, Hentz M, Fait J, Mumby M, Walter G. 1994. Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens. J Virol 68:123-129.
    • (1994) J Virol , vol.68 , pp. 123-129
    • Ruediger, R.1    Hentz, M.2    Fait, J.3    Mumby, M.4    Walter, G.5
  • 25
    • 0035810043 scopus 로고    scopus 로고
    • Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene
    • Ruediger R, Pham HT, Walter G. 2001a. Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene. Oncogene 20:1892-1899.
    • (2001) Oncogene , vol.20 , pp. 1892-1899
    • Ruediger, R.1    Pham, H.T.2    Walter, G.3
  • 26
    • 0035804217 scopus 로고    scopus 로고
    • Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the Aalpha subunit gene
    • Ruediger R, Pham HT, Walter G. 2001b. Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the Aalpha subunit gene. Oncogene 12:10-15.
    • (2001) Oncogene , vol.12 , pp. 10-15
    • Ruediger, R.1    Pham, H.T.2    Walter, G.3
  • 27
    • 0033916381 scopus 로고    scopus 로고
    • Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers
    • Takagi Y, Futamura M, Yamaguchi K, Aoki S, Takahashi T, Saji S. 2000. Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers. Gut 47:268-271.
    • (2000) Gut , vol.47 , pp. 268-271
    • Takagi, Y.1    Futamura, M.2    Yamaguchi, K.3    Aoki, S.4    Takahashi, T.5    Saji, S.6
  • 29
    • 4644344978 scopus 로고    scopus 로고
    • PPP2R1B gene alterations inhibit interaction of PP2A-Abeta and PP2A-C proteins in colorectal cancers
    • Tamaki M, Goi T, Hirono Y, Katayama K, Yamaguchi A. 2004. PPP2R1B gene alterations inhibit interaction of PP2A-Abeta and PP2A-C proteins in colorectal cancers. Oncol Rep 11:655-659.
    • (2004) Oncol Rep , vol.11 , pp. 655-659
    • Tamaki, M.1    Goi, T.2    Hirono, Y.3    Katayama, K.4    Yamaguchi, A.5
  • 30
    • 0027244764 scopus 로고
    • Protein serine/threonine phosphatases and cell transformation
    • Walter G, Mumby M. 1993. Protein serine/threonine phosphatases and cell transformation. Biochim Biophys Acta 1155:207-226.
    • (1993) Biochim Biophys Acta , vol.1155 , pp. 207-226
    • Walter, G.1    Mumby, M.2
  • 32
    • 0032934560 scopus 로고    scopus 로고
    • Refined mapping of two regions of loss of heterozygosity on chromosome band 11q23 in lung cancer
    • Wang SS, Virmani A, Gazdar AF, Minna JD, Evans GA. 1999. Refined mapping of two regions of loss of heterozygosity on chromosome band 11q23 in lung cancer. Genes Chromosomes Cancer 25:154-159.
    • (1999) Genes Chromosomes Cancer , vol.25 , pp. 154-159
    • Wang, S.S.1    Virmani, A.2    Gazdar, A.F.3    Minna, J.D.4    Evans, G.A.5
  • 33
    • 0033972224 scopus 로고    scopus 로고
    • PR48, a novel regulatory subunit of protein phosphatase 2a, interacts with Cdc6 and modulates DMA replication in human cells
    • Yan Z, Fedorov SA, Mumby MC, Williams RS. 2000. PR48, a novel regulatory subunit of protein phosphatase 2a, interacts with Cdc6 and modulates DMA replication in human cells. Mol Cell Biol 20:1021-1029.
    • (2000) Mol Cell Biol , vol.20 , pp. 1021-1029
    • Yan, Z.1    Fedorov, S.A.2    Mumby, M.C.3    Williams, R.S.4
  • 35
    • 0037437370 scopus 로고    scopus 로고
    • Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: Differences in expression, subunit interaction, and evolution
    • Zhou J, Pham HT, Ruediger R, Walter G. 2003. Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution. Biochem J 369:387-398.
    • (2003) Biochem J , vol.369 , pp. 387-398
    • Zhou, J.1    Pham, H.T.2    Ruediger, R.3    Walter, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.