Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesisesis

Cancer Research

Volumn 62, Issue 22, 2002, Pages 6424-6429

  Herzog, Christopher R ^a   Devereux, Theodora R ^b   Pittman, Brian ^a   You, Ming ^c  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; CARBAMIC ACID VINYL ESTER; CARCINOGEN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMOSOMAL PARAMETERS; CHROMOSOME 12; CHROMOSOME 14; CHROMOSOME 4; CHROMOSOME ABERRATION; CONTROLLED STUDY; GENOME; HETEROZYGOSITY LOSS; LUNG ADENOCARCINOMA; LUNG CARCINOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOCARCINOMA; ANIMALS; CARCINOGENS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; MICE; MICE, INBRED A; MICE, INBRED C3H; NITROSAMINES; URETHANE;

EID: 0037112437     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Pejovic, T., Heims, S., Omdal, C., Jin, Y. S., Mandahl, N., Willen, H., and Mitelman, F. Simple numerical chromosome aberrations in well-differentiated malignant epithelial tumors. Cancer Genet. Cytogenet., 49: 95-101, 1990
2. Petersen, I., Bujard, M., Petersen, S., Wolf, G., Goeze, A., Schwendel, A., Langreck, H., Gellert, K., Reichel, M., Just, K., du Manoir, S., Cremer, T., Dietel, M., and Ried, T. Patterns of chromosomal imbalances in adenocarcinoma and squamous cell carcinoma of the lung. Cancer Res., 57: 2331-2335, 1997
3. Sato, S., Nakamura, Y., and Tsuchiya, E. Difference of allelotype between squamous cell carcinoma and adenocarcinoma of the lung. Cancer Res., 54: 5652-5655, 1994
4. Pei, J., Balsara, B. R., Li, W., Litwin, S., Gabrielson, E., Feder, M., Jen, J., and Testa, J. R. Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas. Genes Chromosomes Cancer, 31: 282-287, 2001
5. Herzog, C. R., Wang, Y., and You, M. Allelic loss on distal chromosome 4 in mouse lung tumors localize a putative tumor suppressor gene to a region homologous with human chromosome 1p36. Oncogene, 11: 1811-1815, 1995
6. Herzog, C. R., Wiseman, R. W., and You, M. Deletion mapping of a putative tumor suppressor gene on chromosome 4 in mouse lung tumors. Cancer Res., 54: 4007-4010, 1994
7. Hegi, M. D., Devereux, T. R., Dietrich, W. F., Cochran, C. J., Lander, E. S., Foley, J. F., Maronpot, R. R., Anderson, M. W., and Wiseman, R. W. Allelotype analysis of mouse lung carcinomas reveals frequent allelic losses on chromosome 4 and an association between allelic imbalances on chromosome 6 and K-ras activation. Cancer Res., 54: 6257-6264, 1994
8. Herzog, C. R., Chen, B., Wang, Y., Schut, H. A. J., and You, M., Loss of heterozygosity on chromosomes 1, 11, 12, and 14 in hybrid mouse lung carcinomas. Mol. Carcinog., 16: 83-90, 1996
9. Kok, K., Naylor, S. L., and Buys, C. H., Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes. Adv. Cancer Res., 71: 27-92, 1997
10. Sargent, L. M., Senft, J. R., Lowry, D. T., Jefferson, A. M., Tyson, F. L., Malkinson, A. M., Coleman, A. E., and Reynolds, S. H. Specific chromosomal aberrations in mouse lung adenocarcinoma cell lines detected by spectral karyotyping: A comparison with human lung adenocarcinoma. Cancer Res., 62, 1152-1157, 2002
11. Scholes, A. G., and Field, J. K. Genomic instability in head and neck cancer. Curr. Topics Pathol., 90: 201-222, 1996
12. Lengauer, C., Kinzler, K. W., and Vogelstein, B. Genetic instabilities in human cancers. Nature (Lond.), 396: 643-649, 1998
13. Breivik, J., and Gaudemack, G. Genomic instability, DNA methylation, and natural selection in colorectal carcinogenesis. Semin. Cancer Biol., 9: 245-254, 1999
14. Shin, D. M., Charuruks, N., Lippman, S. M., Lee, J. J., Ro, J. Y., Hong, W. K., and Hittelman, W. N. p53 protein accumulation and genomic instability in head and neck multistep tumorigenesis. Cancer Epidemiol. Biomark. Prev., 10: 603-609, 2001
15. Lung, J. C., Chu, J. S., Yu, J. C., Yue, C. T., Lo, Y. L., Shen, C. Y., and Wu, C. W. Aberrant expression of cell-cycle regulator cyclin DI in breast cancer is related to chromosomal genomic instability. Genes Chromosomes Cancer, 34: 276-284, 2002
16. Hecht, S. S. Tobacco smoke carcinogens and breast cancer. Environ. Mol. Mutagen., 39: 119-126, 2002
17. Fielding, J. E. Smoking: Health effects and control. N. Engl. J. Med., 313: 491-498, 1985
18. IARC. Tobacco smoking, In: IARC Monograph Evaluating Carcinogenic Risks of Chemicals to Humans, pp. 101-102. Lyon, France: IARC, 1986
19. Bardelli, A., Cahill, D. P., Lederer, G., Speicher, M, R., Kinzler, K. W., Vogelstein, B., and Lengauer, C. Carcinogen-specific induction of genetic instability. Proc. Natl. Acad. Sci. USA, 98: 5770-5775, 2001
20. Kawate, H., Sakumi, K., Tsusuki, T., Nakatsuru, Y., Ishikawa, T., Takahashi, S., Takano, H., Noda, T., and Sekiguchi, M. Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes. Proc. Natl. Acad. Sci. USA, 95: 5116-5120, 1998
21. Branch, P., Hampson, R., and Karran, P. DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines. Cancer Res., 55: 2304-2309, 1995
22. Hecht, S. S. DNA adduct formation from tobacco-specific N-nitrosamines. Mutat. Res., 424: 127-142, 1999
23. Cloutier, J. F., Drouin, R., Weinfeld, M., O’Connor, T. R., and Castonguay, A. Characterization and mapping of DNA damage induced by reactive metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) at nucleotide resolution in human genomic DNA. J. Mol. Biol., 313: 539-557, 2001
24. Melikian, A. A., Prahalad, K. A., Amin, S., and Hecht, S. S. Comparative DNA binding of polynuclear aromatic hydrocarbons and their dihydrodiol and bay region diolepoxide metabolites in newborn mouse lung and liver. Carcinogenesis (Lond.), 12: 1665-1670, 1991
25. MacLeod, M. C. Interaction of bulky chemical carcinogens with DNA in chromatin. Carcinogenesis (Lond.), 16: 2009-2014, 1995
26. INK4a-β in mouse lung tumor cells. Oncogene 13: 1885-1891, 1996
27. Herzog, C. R., Noh, S., Lantry, L. E., Guan K.L., and You, M. Cdkn2a encodes functional variation of p16INK4a but not p19ARF which confers selection in mouse lung tumorigenesis. Mol. Carcinog., 25: 92-98, 1999
28. Ballering, L. A., Nivard, M. J., and Vogel, E. W. Preferential formation of deletions following in vivo exposure of postmeitotic Drosophila germ cells to the DNA ethenoadduct-forming carcinogen vinyl carbamate. Environ. Mol. Mutagen., 30: 321-329, 1997
29. Zheng, L., Flesken-Nikitin, A., Chen, P. L., and Lee, W. H. Deficiency of retinoblastoma gene in mouse embryonic stem cells leads to genetic instability. Cancer Res., 62: 2498-2502, 2002
30. Jallepalli, P. V., and Lengauer, C. Chromosome segregation and cancer: Cutting through the mystery. Nat. Rev., Caner, S36-S44, 2001
31. Michel, L. S., Liberal, V., Chatterjee, A., Kirchwegger, R., Pasche, B., Gerald, W., Dobles, M., Sorger, P. K., Murty, V. V. V. S., and Benezra, R. MAD2 haploinsufficiency causes premature anaphase and chromosome instability in mammalian cells. Nature (Lond.), 409: 355-359, 2001
32. Zhang, W. Y. H., Schoenberg, M. P., Polascik, T. C., Cairns, P., and Sidransky, D. Novel suppressor loci on chromosome 14q in primary bladder cancer. Cancer Res., 55: 3246-3249, 1995
33. Abujiang, P., Mori, T. J., Takahashi, T., Tanaka, F., Kasyu, I., Hitomi, S., and Hiai, H. Loss of heterozygosity (LOH) at 17q and 14q in human lung cancers. Oncogene, 17: 3029-3033, 1998
34. Cahill, D. P., Lengauer, C., Yu, J., Riggins, G. J., Willson, J. K., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. Mutations of mitotic checkpoint genes in human cancers. Nature (Lond.), 392: 300-303, 1998
35. Smith, M. L., and Fornace, A. J., Jr. Genomic instability and the role of p53 mutations in cancer cells. Curr. Opin. Oncol., 7: 69-75, 1995
36. Tam, A. S., Foley, J. F., Devereux, T. R., Maronpot, R. R., and Massey, T. E. High frequency and heterogeneous distribution of p53 mutations in aflatoxin B1-induced mouse lung tumors. Cancer Res., 59: 3634-3640, 1999