-
1
-
-
0023907493
-
Interleukin-2: Inception, impact, and implications
-
K.A. Smith Interleukin-2: inception, impact, and implications Science 240 1988 1169 1176
-
(1988)
Science
, vol.240
, pp. 1169-1176
-
-
Smith, K.A.1
-
2
-
-
0025899598
-
Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
-
H. Schorle, T. Holtschke, T. Hunig, A. Schimpl, and I. Horak Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting Nature 352 1991 621 624
-
(1991)
Nature
, vol.352
, pp. 621-624
-
-
Schorle, H.1
Holtschke, T.2
Hunig, T.3
Schimpl, A.4
Horak, I.5
-
3
-
-
0030272248
-
IL-2 and IL-2 receptors: Recent advances and new immunological functions
-
J. Thèze, P. Alzari, and J. Bertoglio IL-2 and IL-2 receptors: recent advances and new immunological functions Immunol Today 17 1996 481 486
-
(1996)
Immunol Today
, vol.17
, pp. 481-486
-
-
Thèze, J.1
Alzari, P.2
Bertoglio, J.3
-
4
-
-
0035132135
-
IL-15 and IL-2: A matter of life and death for T cells in vivo
-
X.C. Li, G. Demirci, S. Ferrari-Lacraz, C. Groves, A. Coyle, and T.R. Malek IL-15 and IL-2: a matter of life and death for T cells in vivo Nat Med 7 2001 114 118
-
(2001)
Nat Med
, vol.7
, pp. 114-118
-
-
Li, X.C.1
Demirci, G.2
Ferrari-Lacraz, S.3
Groves, C.4
Coyle, A.5
Malek, T.R.6
-
5
-
-
0022871958
-
Clinical effects and toxicity of interleukin-2 in patients with cancer
-
M. Lotze, Y. Matory, A. Rayner, S. Ettinghausen, J. Vetto, and C. Seipp Clinical effects and toxicity of interleukin-2 in patients with cancer Cancer 58 1986 2764 2772
-
(1986)
Cancer
, vol.58
, pp. 2764-2772
-
-
Lotze, M.1
Matory, Y.2
Rayner, A.3
Ettinghausen, S.4
Vetto, J.5
Seipp, C.6
-
6
-
-
0023115642
-
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone
-
S.A. Rosenberg, M.T. Lotze, L.M. Muul, A.E. Chang, F.P. Avis, and S. Leitman A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone N Engl J Med 316 1987 889 897
-
(1987)
N Engl J Med
, vol.316
, pp. 889-897
-
-
Rosenberg, S.A.1
Lotze, M.T.2
Muul, L.M.3
Chang, A.E.4
Avis, F.P.5
Leitman, S.6
-
7
-
-
0029811148
-
Rational interleukin 2 therapy for HIV positive individuals: Daily low doses enhance immune function without toxicity
-
E. Leef Jacobson, F. Pilaro, and K.A. Smith Rational interleukin 2 therapy for HIV positive individuals: daily low doses enhance immune function without toxicity Proc Natl Acad Sci U S A 93 1996 10405 10410
-
(1996)
Proc Natl Acad Sci U S a
, vol.93
, pp. 10405-10410
-
-
Leef Jacobson, E.1
Pilaro, F.2
Smith, K.A.3
-
8
-
-
0035282639
-
Rapid effect of interleukin-2 therapy in human immunodeficiency virus-infected patients whose CD4 cell counts increase only slightly in response to combined antiretroviral treatment
-
D. David, L. Nait-Ighil, B. Dupont, J. Maral, B. Gachot, and J. Theze Rapid effect of interleukin-2 therapy in human immunodeficiency virus-infected patients whose CD4 cell counts increase only slightly in response to combined antiretroviral treatment J Infect Dis 183 2001 730 735
-
(2001)
J Infect Dis
, vol.183
, pp. 730-735
-
-
David, D.1
Nait-Ighil, L.2
Dupont, B.3
Maral, J.4
Gachot, B.5
Theze, J.6
-
9
-
-
0035090186
-
Low-dose daily interleukin-2 immunotherapy: Accelerating immune restoration and expanding HIV-specific T-cell immunity without toxicity
-
K.A. Smith Low-dose daily interleukin-2 immunotherapy: accelerating immune restoration and expanding HIV-specific T-cell immunity without toxicity AIDS 15 Suppl 2 2001 S28 S35
-
(2001)
AIDS
, vol.15
, Issue.2 SUPPL.
-
-
Smith, K.A.1
-
11
-
-
0036678129
-
Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection
-
V. Natarajan, R.A. Lempicki, I. Sereti, Y. Badralmaa, J.W. Adelsberger, and J.A. Metcalf Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection Proc Natl Acad Sci U S A 99 2002 10712 10717
-
(2002)
Proc Natl Acad Sci U S a
, vol.99
, pp. 10712-10717
-
-
Natarajan, V.1
Lempicki, R.A.2
Sereti, I.3
Badralmaa, Y.4
Adelsberger, J.W.5
Metcalf, J.A.6
-
12
-
-
0032990632
-
Activation of endothelium by immunotherapy with interleukin-2 in patients with malignant disorders
-
G.J. Locker, S. Kapiotis, M. Veitl, R.M. Mader, B. Stoiser, and J. Kofler Activation of endothelium by immunotherapy with interleukin-2 in patients with malignant disorders Br J Haematol 105 1999 912 919
-
(1999)
Br J Haematol
, vol.105
, pp. 912-919
-
-
Locker, G.J.1
Kapiotis, S.2
Veitl, M.3
Mader, R.M.4
Stoiser, B.5
Kofler, J.6
-
13
-
-
0032943428
-
Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2
-
A. Lentsch, F. Miller, and M. Edwards Mechanisms of leukocyte-mediated tissue injury induced by interleukin-2 Cancer Immunol Immunother 47 1999 243 248
-
(1999)
Cancer Immunol Immunother
, vol.47
, pp. 243-248
-
-
Lentsch, A.1
Miller, F.2
Edwards, M.3
-
14
-
-
2942560498
-
NK cells and polymorphonuclear neutrophils are both critical for IL-2-induced pulmonary vascular leak syndrome
-
E. Assier, V. Jullien, J. Lefort, J.L. Moreau, J.P. Di Santo, and B.B. Vargaftig NK cells and polymorphonuclear neutrophils are both critical for IL-2-induced pulmonary vascular leak syndrome J Immunol 172 2004 7661 7668
-
(2004)
J Immunol
, vol.172
, pp. 7661-7668
-
-
Assier, E.1
Jullien, V.2
Lefort, J.3
Moreau, J.L.4
Di Santo, J.P.5
Vargaftig, B.B.6
-
15
-
-
0019421207
-
A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells
-
T. Uchiyama, S. Broder, and T.A. Waldmann A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells J Immunol 126 1981 1393 1397
-
(1981)
J Immunol
, vol.126
, pp. 1393-1397
-
-
Uchiyama, T.1
Broder, S.2
Waldmann, T.A.3
-
16
-
-
0021193219
-
Molecular cloning and expression of cDNAs for the human interleukin-2 receptor
-
W.J. Leonard, J.M. Depper, G.R. Crabtree, S. Rudikoff, J. Pumphrey, and R.J. Robb Molecular cloning and expression of cDNAs for the human interleukin-2 receptor Nature 311 1984 626 631
-
(1984)
Nature
, vol.311
, pp. 626-631
-
-
Leonard, W.J.1
Depper, J.M.2
Crabtree, G.R.3
Rudikoff, S.4
Pumphrey, J.5
Robb, R.J.6
-
17
-
-
0023140359
-
Interleukin 2 high-affinity receptor expression requires two distinct binding proteins
-
K. Teshigawara, H.M. Wang, K. Kato, and K.A. Smith Interleukin 2 high-affinity receptor expression requires two distinct binding proteins J Exp Med 165 1987 223 238
-
(1987)
J Exp Med
, vol.165
, pp. 223-238
-
-
Teshigawara, K.1
Wang, H.M.2
Kato, K.3
Smith, K.A.4
-
18
-
-
0024403321
-
Interleukin-2 receptor beta chain gene: Generation of three receptor forms by cloned human alpha and beta chain cDNA's
-
M. Hatakeyama, M. Tsudo, S. Minamoto, T. Kono, T. Doi, and T. Miyata Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's Science 244 1989 551 556
-
(1989)
Science
, vol.244
, pp. 551-556
-
-
Hatakeyama, M.1
Tsudo, M.2
Minamoto, S.3
Kono, T.4
Doi, T.5
Miyata, T.6
-
19
-
-
3042932317
-
Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies
-
M. Tsudo, F. Kitamura, and M. Miyasaka Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies Proc Natl Acad Sci U S A 86 1989 1982 1986
-
(1989)
Proc Natl Acad Sci U S a
, vol.86
, pp. 1982-1986
-
-
Tsudo, M.1
Kitamura, F.2
Miyasaka, M.3
-
20
-
-
0026684134
-
Cloning of the gamma chain of the human IL-2 receptor
-
T. Takeshita, H. Asao, K. Ohtani, N. Ishii, S. Kumaki, and N. Tanaka Cloning of the gamma chain of the human IL-2 receptor Science 257 1992 379 382
-
(1992)
Science
, vol.257
, pp. 379-382
-
-
Takeshita, T.1
Asao, H.2
Ohtani, K.3
Ishii, N.4
Kumaki, S.5
Tanaka, N.6
-
21
-
-
9644295710
-
Cytokines and immunodeficiency diseases: Critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
-
P.E. Kovanen, and W.J. Leonard Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways Immunol Rev 202 2004 67 83
-
(2004)
Immunol Rev
, vol.202
, pp. 67-83
-
-
Kovanen, P.E.1
Leonard, W.J.2
-
22
-
-
17944400837
-
Further analysis of interleukin-2 receptor subunit expression on the different human peripheral blood mononuclear cell subsets
-
D. David, L. Bani, J.L. Moreau, C. Demaison, K. Sun, and O. Salvucci Further analysis of interleukin-2 receptor subunit expression on the different human peripheral blood mononuclear cell subsets Blood 91 1998 165 172
-
(1998)
Blood
, vol.91
, pp. 165-172
-
-
David, D.1
Bani, L.2
Moreau, J.L.3
Demaison, C.4
Sun, K.5
Salvucci, O.6
-
23
-
-
0030033393
-
Lack of intermediate affinity IL-2 receptor in mice leads to dependence on IL-2 receptor α, β and γ chain expression for T cell growth
-
P. Chastagner, J.L. Moreau, Y. Jacques, T. Tanaka, M. Miyasaka, and M. Kondo Lack of intermediate affinity IL-2 receptor in mice leads to dependence on IL-2 receptor α, β and γ chain expression for T cell growth Eur J Immunol 26 1996 201 206
-
(1996)
Eur J Immunol
, vol.26
, pp. 201-206
-
-
Chastagner, P.1
Moreau, J.L.2
Jacques, Y.3
Tanaka, T.4
Miyasaka, M.5
Kondo, M.6
-
24
-
-
0029819395
-
Ligand-induced autoregulation of IL-2 receptor alpha chain expression in murine T cell lines
-
C. Demaison, P. Chastagner, J.L. Moreau, and J. Theze Ligand-induced autoregulation of IL-2 receptor alpha chain expression in murine T cell lines Int Immunol 8 1996 1521 1528
-
(1996)
Int Immunol
, vol.8
, pp. 1521-1528
-
-
Demaison, C.1
Chastagner, P.2
Moreau, J.L.3
Theze, J.4
-
25
-
-
0027943757
-
IL-2 can support growth of CD8+ T cells but not CD4+ T cells of human IL-2 receptor beta-chain transgenic mice
-
M. Asano, Y. Ishida, H. Sabe, M. Kondo, K. Sugamura, and T. Honjo IL-2 can support growth of CD8+ T cells but not CD4+ T cells of human IL-2 receptor beta-chain transgenic mice J Immunol 153 1994 5373 5381
-
(1994)
J Immunol
, vol.153
, pp. 5373-5381
-
-
Asano, M.1
Ishida, Y.2
Sabe, H.3
Kondo, M.4
Sugamura, K.5
Honjo, T.6
-
26
-
-
23844460275
-
IL-2 responsiveness of CD4 and CD8 lymphocytes: Further investigations with human IL-2Rbeta transgenic mice
-
F. Gesbert, J.L. Moreau, and J. Theze IL-2 responsiveness of CD4 and CD8 lymphocytes: further investigations with human IL-2Rbeta transgenic mice Int Immunol 17 2005 1093 1102
-
(2005)
Int Immunol
, vol.17
, pp. 1093-1102
-
-
Gesbert, F.1
Moreau, J.L.2
Theze, J.3
-
27
-
-
0027521474
-
High-affinity and intermediate-affinity forms of the human interleukin 2 receptor, expressed in an interleukin 9-dependent murine T cell line, deliver proliferative signals via differences in their transduction pathways
-
C. Pitton, A. Rebollo, J. Van Snick, J. Theze, and A. Garcia High-affinity and intermediate-affinity forms of the human interleukin 2 receptor, expressed in an interleukin 9-dependent murine T cell line, deliver proliferative signals via differences in their transduction pathways Cytokine 5 1993 362 371
-
(1993)
Cytokine
, vol.5
, pp. 362-371
-
-
Pitton, C.1
Rebollo, A.2
Van Snick, J.3
Theze, J.4
Garcia, A.5
-
28
-
-
0034614890
-
The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cells
-
R. Eckenberg, T. Rose, J.L. Moreau, R. Weil, F. Gesbert, and S. Dubois The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cells J Exp Med 191 2000 529 540
-
(2000)
J Exp Med
, vol.191
, pp. 529-540
-
-
Eckenberg, R.1
Rose, T.2
Moreau, J.L.3
Weil, R.4
Gesbert, F.5
Dubois, S.6
-
29
-
-
0030800586
-
Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography
-
E. Hamelmann, J. Schwarze, K. Takeda, A. Oshiba, G.L. Larsen, and C.G. Irvin Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography Am J Respir Crit Care Med 156 1997 766 775
-
(1997)
Am J Respir Crit Care Med
, vol.156
, pp. 766-775
-
-
Hamelmann, E.1
Schwarze, J.2
Takeda, K.3
Oshiba, A.4
Larsen, G.L.5
Irvin, C.G.6
-
30
-
-
0024819767
-
Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat
-
J.S. Warren, K.R. Yabroff, D.G. Remick, S.L. Kunkel, S.W. Chensue, and R.G. Kunkel Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat J Clin Invest 84 1989 1873 1882
-
(1989)
J Clin Invest
, vol.84
, pp. 1873-1882
-
-
Warren, J.S.1
Yabroff, K.R.2
Remick, D.G.3
Kunkel, S.L.4
Chensue, S.W.5
Kunkel, R.G.6
-
31
-
-
0029999719
-
Migratory responses of PMN after intraperitoneal and intratracheal administration of lipopolysaccharide
-
S. Hirano Migratory responses of PMN after intraperitoneal and intratracheal administration of lipopolysaccharide Am J Physiol 270 1996 L836 L845
-
(1996)
Am J Physiol
, vol.270
-
-
Hirano, S.1
-
32
-
-
0032529619
-
IL-2 receptor alpha-chain expression is independently regulated in primary and secondary lymphoid organs
-
C. Demaison, L. Fiette, V. Blanchetiere, A. Schimpl, J. Theze, and P. Froussard IL-2 receptor alpha-chain expression is independently regulated in primary and secondary lymphoid organs J Immunol 161 1998 1977 1982
-
(1998)
J Immunol
, vol.161
, pp. 1977-1982
-
-
Demaison, C.1
Fiette, L.2
Blanchetiere, V.3
Schimpl, A.4
Theze, J.5
Froussard, P.6
-
33
-
-
0348047537
-
The main function of IL-2 is to promote the development of T regulatory cells
-
T.R. Malek The main function of IL-2 is to promote the development of T regulatory cells J Leukoc Biol 74 2003 961 965
-
(2003)
J Leukoc Biol
, vol.74
, pp. 961-965
-
-
Malek, T.R.1
-
34
-
-
16244388978
-
Histamine improves survival and protects against interleukin-2-induced pulmonary vascular leak syndrome in mice
-
S.C. Hornyak, D.M. Orentas, L.M. Karavodin, and K.R. Gehlsen Histamine improves survival and protects against interleukin-2-induced pulmonary vascular leak syndrome in mice Vascul Pharmacol 42 2005 187 193
-
(2005)
Vascul Pharmacol
, vol.42
, pp. 187-193
-
-
Hornyak, S.C.1
Orentas, D.M.2
Karavodin, L.M.3
Gehlsen, K.R.4
-
35
-
-
0036842324
-
Regulation of interleukin-2-induced vascular leak syndrome by targeting CD44 using hyaluronic acid and anti-CD44 antibodies
-
A. Mustafa, R.J. McKallip, M. Fisher, R. Duncan, P.S. Nagarkatti, and M. Nagarkatti Regulation of interleukin-2-induced vascular leak syndrome by targeting CD44 using hyaluronic acid and anti-CD44 antibodies J Immunother 25 2002 476 488
-
(2002)
J Immunother
, vol.25
, pp. 476-488
-
-
Mustafa, A.1
McKallip, R.J.2
Fisher, M.3
Duncan, R.4
Nagarkatti, P.S.5
Nagarkatti, M.6
-
36
-
-
0242384768
-
Targeted deletion of CD44v7 exon leads to decreased endothelial cell injury but not tumor cell killing mediated by interleukin-2-activated cytolytic lymphocytes
-
R.J. McKallip, M. Fisher, Y. Do, A.K. Szakal, U. Gunthert, and P.S. Nagarkatti Targeted deletion of CD44v7 exon leads to decreased endothelial cell injury but not tumor cell killing mediated by interleukin-2-activated cytolytic lymphocytes J Biol Chem 278 2003 43818 43830
-
(2003)
J Biol Chem
, vol.278
, pp. 43818-43830
-
-
McKallip, R.J.1
Fisher, M.2
Do, Y.3
Szakal, A.K.4
Gunthert, U.5
Nagarkatti, P.S.6
-
37
-
-
0037777543
-
Generation of low-toxicity interleukin-2 fusion proteins devoid of vasopermeability activity
-
P. Hu, M. Mizokami, G. Ruoff, L.A. Khawli, and A.L. Epstein Generation of low-toxicity interleukin-2 fusion proteins devoid of vasopermeability activity Blood 101 2003 4853 4861
-
(2003)
Blood
, vol.101
, pp. 4853-4861
-
-
Hu, P.1
Mizokami, M.2
Ruoff, G.3
Khawli, L.A.4
Epstein, A.L.5
-
38
-
-
0038265184
-
Structural analysis and modeling of a synthetic interleukin-2 mimetic and its interleukin-2Rbeta2 receptor
-
T. Rose, J.L. Moreau, R. Eckenberg, and J. Theze Structural analysis and modeling of a synthetic interleukin-2 mimetic and its interleukin-2Rbeta2 receptor J Biol Chem 278 2003 22868 22876
-
(2003)
J Biol Chem
, vol.278
, pp. 22868-22876
-
-
Rose, T.1
Moreau, J.L.2
Eckenberg, R.3
Theze, J.4
|