Incorporation of a nanosplitter interface into an LC-MS-RD system to facilitate drug metabolism studies

Journal of Mass Spectrometry

Volumn 41, Issue 1, 2006, Pages 43-49

  Andrews, Christine L ^a,d   Li, Feng ^b   Yang, Eric ^b   Yu, Chung Ping ^b   Vouros, Paul ^a,c  

^a NORTHEASTERN UNIVERSITY   (United States)

^b GLAXOSMITHKLINE   (United States)

^c 102 Hurtig Hall ^*  (United States)

^d TUFTS MEDICAL CENTER   (United States)

Author keywords

Drug metabolism; LC MS; Microspray mass spectrometry; Nanosplitter; Radiometry

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITES; NANOSTRUCTURED MATERIALS; RADIOMETRY;

DRUG METABOLISM; MICROSPRAY MASS SPECTROMETRY; NANOSPLITTER INTERFACE;

DRUG PRODUCTS;

ANIMAL CELL; ARTICLE; DEVICE; DRUG DETERMINATION; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NANOSPLITTER; NANOTECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; RADIOMETRY; RAT; SENSITIVITY AND SPECIFICITY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLYCOGEN SYNTHASE KINASES; HAPLORHINI; HEPATOCYTES; MASS SPECTROMETRY; NANOTECHNOLOGY; PHARMACEUTICAL PREPARATIONS; RATS; REFERENCE STANDARDS;

ANIMALIA;

EID: 31544444688     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.944     Document Type: Article

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