Neural stem cell biology provides insights into new therapeutic strategies for hypoxic-ischemic brain injury

New Concepts in Cerebral Ischemia

Volumn , Issue , 2001, Pages 61-78

  Park, Kook In ^a   Snyder, Evan Y ^b  

^a Yonsei University College of Medicine   (South Korea)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 3142759879     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (56)

1. Davenport, R. and Dennis, M., Neurological emergencies: acute stroke, J. Neurol. Neurosurg. Psych., 68, 277, 2000.
2. Sudlow, C. and Warlow, C., Comparing stroke incidence worldwide. What makes studies comparable?, Stroke, 27, 550, 1996.
3. Warlow, C. P., et al., The organization of stroke services, in Stroke. A Practical Guide to Management, Warlow, C.P. et al. (eds.), Blackwell, Oxford, 1996, 598.
4. Volpe, J.J., Neurology of the Newborn, 3rd ed., WB Saunders Company, Philadelphia, 1995.
5. Vannucci, R.C. and Perlman, J.M., Interventions for perinatal hypoxic-ischemic encephalopathy, Pediatrics, 100, 1004, 1997.
6. du Plessis, A.J. and Johnston, M.V., Hypoxic-ischemic brain injury in the newborn. Cellular mechanisms and potential strategies for neuroprotection, Clin. Perinatol., 24, 627, 1997.
7. del Zoppo, G., et al., Inflammation and stroke: putative role for cytokines, adhesion molecules and iNOS in brain response to ischemia, Brain Pathol., 10, 95, 2000.
8. Tan, S. and Parks, D. A., Preserving brain function during neonatal asphyxia, Clin. Perinatol., 26, 733, 1999.
9. Snyder, E.Y. and Wolfe, J.H., CNS cell transplantation: a novel therapy for storage diseases?, Curr. Opin. Neurol., 9, 126, 1996.
10. Snyder, E.Y. and Fisher, L.J., Gene therapy for neurologic diseases, Curr. Opin. Pediatr., 8, 558, 1996.
11. Snyder, E.Y. and Senut, M.C., Use of non-neuronal cells for gene delivery, Neurobiol. Dis., 4, 69, 1997.
12. Martinez-Serrano, A., et al., CNS-derived neural progenitor cells for gene transfer to nerve growth factor to the adult rat brain: complete rescue of axotomized cholinergic neurons after implantation into the septum, J. Neurosci., 15, 5668, 1995.
13. Martinez-Serrano, A., Fischer, W., and Bj?rklund, A., Reversal of age-dependent cognitive impairments and cholinergic neuronal atrophy by NGF-secreting neural progenitors grafted to the basal forebrain, Neuron, 15, 473, 1995.
14. Martinez-Serrano, A., et al., Longterm functional recovery from age-induced spatial memory impaiments by nerve growth factor gene transfer to the rat basal forebrain, Proc. Natl. Acad. Sci. USA, 93, 6355, 1996.
15. Martinez-Serrano, A. and Bjklund, A., Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells, J. Neurosci., 16, 4604, 1996.
16. Martinez-Serrano, A. and Snyder, E.Y., Neural stem cell lines for CNS regeneration:Basic Science and Clinical Applications, in CNS Regeneration, Tuszynski, M. and Kordower, J. (eds.), Academic Press, San Diego, 1999, 203.
17. Snyder, E.Y., Taylor, R.M., and Wolfe, J.H., Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain, Nature, 374, 367, 1995.
18. Lacorazza, H.D., et al., Expression of human β-hexosaminidase α-subunit gene (the gene defect of Tay-Sachs disease) in mouse brains upon engraftment of transduced progenitor cells, Nat. Med., 2, 424, 1996.
19. Lynch, W.P., et al., Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived cheimeric mouse brains, J. Virol., 70, 8896, 1996.
20. Lynch, W.P., Shapre, A.H., and Snyder, E.Y., Neural stem cells as engraftable packaging lines optimize viral vector-mediated gene delivery to the CNS evidence from studying retroviral env-related neurodegeneration, J. Virol., 73, 6481, 1999.
21. Billinghurst, L.L., Taylor, R.M., and Snyder, E.Y., Remyelination: cellular and gene therapy, Sem. Pediatr. Neurol., 5, 211, 1998.
22. Flax, J.D., et al., Engraftable human neural stem cells respond to developmental cues, replace neurons and express foreign genes, Nat. Biotech., 16, 1033, 1998.
23. Yandava, B.D., Billinghurst, L.L., and Snyder, E.Y., “Global” cell replacement is feasible via neural stem cell transplantation: evidence from the dysmyelinated shiverer mouse brain, Proc. Natl. Acad. Sci. USA, 96, 7029, 1999.
24. Snyder, E.Y. and Macklis, J.D., Multipotent neural progenitor or stem-like cells may be uniquely suited for therapy for some neurodegenerative conditions, Clin. Neurosci., 3, 310, 1996.
25. Snyder, E.Y. et al., Multipotent neural precursors can differentiate toward replacements of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex, Proc. Natl. Acad. Sci. USA, 94, 11663, 1997.
26. Rosario, C.M. et al., Differentiation of engrafted multipotent neural progenitors towards replacement of missing granule neurons in Meander tail cerebellum may help determine the locus of mutant gene action, Development, 124, 4213, 1997.
27. Park, K.I., Jensen, F.E., and Snyder, E.Y., Nerual progenitor transplantation for hypoxic- ischemic brain injury in immature mice, Soc. Neurosci. Abs., 21, 2027, 1995.
28. Snyder, E.Y. et al., Multipotent neural cell lines can engraft and participate in development of mouse cerebellum, Cell, 68, 33, 1992.
29. Snyder, E.Y. et al., Transplantation and differentiation of neural “stem-like” cells:possible insights into development and therapeutic potential, in Research and Perspectives in Neurosciences: Isolation, Characterization, and Utilization of CNS stem cells, Gage, F.H. and Christen, Y. (eds.), Springer-Verlag, New York, 1997, 173.
30. Snyder, E.Y., Neural stem-like cells: developmental lessons with therapeutic potential, Neurosci., 4, 408, 1998.
31. Gage, F.H. et al., Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain, Proc. Natl. Acad. Sci. USA, 92, 11879, 1995.
32. Ghosh, A. and Greenberg, M.E., Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis, Neuron, 15, 89, 1995.
33. Johe, K.K. et al., Single factors direct the differentiation of stem cells from the fetal and adult central nervous system, Genes Dev., 10, 3129, 1996.
34. Liu, Y. et al., Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus, Exp. Neurol., 158, 9, 1999.
35. Park, K.I. et al., Transplantation of neurotrophin-3 (NT-3) expressing neural stem-like cells into hypoxic-ischemic brain injury, Soc. Neurosci. Abs., 23, 346, 1997.
36. Sidman, R.L., Miale, I.L., and Feder, N., Cell proliferation and migration in the primitive ependymal zone: an autoradiographic study of histogenesis in the nervous system, Exp. Neurol., 1, 322, 1959.
37. Altman, J. and Das, G.D., Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats, J. Comp. Neurol., 124, 319, 1965.
38. Altman, J., Autoradiographic and histological studies of postnatal neurogenesis: IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb, J. Comp. Neurol., 137, 433, 1969.
39. Lois, C. and Alvarez-Buylla, A., Long distance neuronal migration in the adult mammalian brain, Science, 264, 1145, 1994.
40. Lois, C., Garcia-Verdugo, J. M., and Alvarez-Buylla, A., Chain migration of neuronal precursors, Science, 271, 978, 1996.
41. Goldman, S.A. and Luskin, M.B., Strategies utilized by migrating neurons of the postnatal vertebrate forebrain, Trend Neurosci., 21, 107, 1998.
42. Kakita, A. and Goldman, J.E., Patterns and dynamics of SVZ cell migration in the postnatal forebrain: monitoring living progenitors in slice preparation, Neuron, 23, 461, 1999.
43. Wei, W., et al., Directional guidance of neuronal migration in the olfactory system by protein slit, Nature, 400, 331, 1999.
44. Eriksson, P.S., et al., Neurogenesis in the adult human hippocampus, Nat. Med., 4, 1313, 1998.
45. Pincus, D.W., et al., FGF2/BDNF-associated maturation of new neurons generated from adult human subependymal cells, Ann. Neurol., 43, 576, 1998.
46. Ramon y Cajal, S., Degeneration and Regeneration of the Nervous System, Oxford University Press, London, 1928.
47. Park, K.I. and Snyder, E.Y., Transplantation of human neural stem cells, propagated by either genetic or epigenetic means, into hypoxic-ischemic (HI) brain injury, Soc. Neurosci. Abs., 25, 212, 1999.
48. Price, J., Turner, D., and Cepko, C., Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer, Proc. Natl. Acad. Sci. USA, 84, 156, 1987.
49. Svendsen, C. N., et al., Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson’s disease, Exp. Neurol., 148, 135, 1997.
50. Vescovi, A.L., et al., Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation, Exp. Neurol., 156, 71, 1999.
51. Fricker, R.A., et al., Site-specific migration and neuronal differentiation of human neural progenitor cells after transplantation in the adult rat brain, J. Neurosci., 19, 5990, 1999.
52. Villa, A., et al., Establishment and properties of a growth factor-dependent, perpetual neural stem cell line from the human CNS, Exp. Neurol., 161, 67, 2000.
53. Javier Rubio, F. et al., Genetically perpetuated human neural stem cells engraft and differentiate into the adult mammalian brain, Mol. Cell. Neurosci., 16, 1, 2000.
54. Park, K.I. and Snyder, E.Y., Transplantation of human neural stem cells, propagated by either genetic or epigenetic means, into hypoxic-ischemic (HI) brain injury, Soc. Neurosci. Abs., 25, 212, 1999.
55. Park, K.I., et al., Transplantation of neural stem cells (NSCs) seeded in biodegradable polyglycolic acid (PGA) into hypoxic-ischemic (HI) brain injury, Soc. Neurosci. Abs., 26, 868, 2000.
56. Shalaby, S.W. and Johnson, R.A., Synthetic absorbable polyesters, in Biomedical Polymers, Shalaby, S.W. (ed.), Carl Hanser, 1994, 2.