Bile acid conjugates of a nonsteroidal glucocorticoid receptor modulator

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 16, 2004, Pages 4179-4183

  Tu, Noah ^a,c   Link, J T ^a   Sorensen, Bryan K ^a   Emery, Maurice ^a,d   Grynfarb, Marlena ^b   Goos Nilsson, Annika ^b   Nguyen, Bach ^a  

^a ABBOTT LABORATORIES   (United States)

^b Karo Bio   (Sweden)

^c S BIO Pte Ltd   (Singapore)

^d AMGEN INC   (United States)

Author keywords

Bile acid; Conjugate; Glucocorticoid receptor modulator

Indexed keywords

ANTIDIABETIC AGENT; BILE ACID; CHOLIC ACID; GLUCOCORTICOID RECEPTOR ANTAGONIST; MIFEPRISTONE; TAUROCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG METABOLISM; DRUG POTENCY; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; NONHUMAN; RAT; RECEPTOR BINDING;

ANIMALS; BILE ACIDS AND SALTS; BIOLOGICAL AVAILABILITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID;

EID: 3142746761     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.06.022     Document Type: Article

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