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Volumn 36, Issue 2, 2004, Pages 191-196

Rationale of platelet gel to augment adaptive remodeling of the injured heart

Author keywords

Fibroblasts; Growth factors; Remodeling

Indexed keywords

CHEMOKINE; CYTOKINE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; GROWTH HORMONE; INTERLEUKIN 1BETA; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN; THROMBOCYTE CONCENTRATE; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA;

EID: 3142742302     PISSN: 00221058     EISSN: 29698960     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 0030666361 scopus 로고    scopus 로고
    • Platelet gel: An autologous alternative to fibrin glue with applications in oral and maxillofacial surgery
    • Whitman DH, Berry RL, Green DM. Platelet gel: An autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofacial Surg. 1997;55:1294-9.
    • (1997) J Oral Maxillofacial Surg , vol.55 , pp. 1294-1299
    • Whitman, D.H.1    Berry, R.L.2    Green, D.M.3
  • 2
    • 0034850723 scopus 로고    scopus 로고
    • Intraoperative plateletpheresis and autologous platelet gel do not reduce chest tube drainage or allogeneic blood transfusion after reoperative coronary artery bypass graft
    • Wajon P, Gibson J, Calcroft R, et al. Intraoperative plateletpheresis and autologous platelet gel do not reduce chest tube drainage or allogeneic blood transfusion after reoperative coronary artery bypass graft. Anesth Analges. 2001;93:536-42.
    • (2001) Anesth Analges , vol.93 , pp. 536-542
    • Wajon, P.1    Gibson, J.2    Calcroft, R.3
  • 3
    • 85160883803 scopus 로고    scopus 로고
    • Multicomponent pheresis and autologous platelet gel in adolescent spinal surgery
    • Gillingham B, Polston G, Hannon T, et al. Multicomponent pheresis and autologous platelet gel in adolescent spinal surgery. Pediatrics. 1999;104:708-9.
    • (1999) Pediatrics , vol.104 , pp. 708-709
    • Gillingham, B.1    Polston, G.2    Hannon, T.3
  • 4
    • 0036260505 scopus 로고    scopus 로고
    • Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: Preliminary results
    • Robiony M, Polini F, Costa F, et al. Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: Preliminary results. J Oral Maxillofacial Surg. 2002;60:630-5.
    • (2002) J Oral Maxillofacial Surg , vol.60 , pp. 630-635
    • Robiony, M.1    Polini, F.2    Costa, F.3
  • 5
    • 0036911129 scopus 로고    scopus 로고
    • Molecular mechanisms of myocardial remodeling. The role of aldosterone
    • Delcayre C, Swynghedauw B. Molecular mechanisms of myocardial remodeling. The role of aldosterone. J Molec Cellu Cardiol. 2002;34:1577-84.
    • (2002) J Molec Cellu Cardiol , vol.34 , pp. 1577-1584
    • Delcayre, C.1    Swynghedauw, B.2
  • 6
    • 0035940392 scopus 로고    scopus 로고
    • Scaffold-based three dimensional human fibroblast culture provides a structural matrix that supports angiogenesis in infracted heart tissue
    • Kellar RS, Lundeen TK, Shepard BR, Naughton GK, Ratchlife A, Williams SK. Scaffold-based three dimensional human fibroblast culture provides a structural matrix that supports angiogenesis in infracted heart tissue. Circulation. 2001;104:2063-8.
    • (2001) Circulation , vol.104 , pp. 2063-2068
    • Kellar, R.S.1    Lundeen, T.K.2    Shepard, B.R.3    Naughton, G.K.4    Ratchlife, A.5    Williams, S.K.6
  • 7
    • 0024444618 scopus 로고
    • Effects of platelet-derived growth-factor on bone-formation in vitro
    • Canalis E, McCarthy TL, Centrella M. Effects of platelet-derived growth-factor on bone-formation in vitro. J Cellu Physiol. 1989;140:530-7.
    • (1989) J Cellu Physiol , vol.140 , pp. 530-537
    • Canalis, E.1    McCarthy, T.L.2    Centrella, M.3
  • 8
    • 0036257762 scopus 로고    scopus 로고
    • Use of topical recombinant human platelet-derived growth factor BB in abdominal wound separation
    • Shackelford DP, Fackler E, Hoffman MK, et al. Use of topical recombinant human platelet-derived growth factor BB in abdominal wound separation. Am J Obst Gynecol. 2002;186:701-4.
    • (2002) Am J Obst Gynecol , vol.186 , pp. 701-704
    • Shackelford, D.P.1    Fackler, E.2    Hoffman, M.K.3
  • 9
    • 0034778574 scopus 로고    scopus 로고
    • Different preparation methods to obtain platelet components as a source of growth factors for local application
    • Zimmermann R, Jakubietz R, Jakubietz M, et al. Different preparation methods to obtain platelet components as a source of growth factors for local application. Transfusion. 2001;41:1217-24.
    • (2001) Transfusion , vol.41 , pp. 1217-1224
    • Zimmermann, R.1    Jakubietz, R.2    Jakubietz, M.3
  • 10
    • 0034104577 scopus 로고    scopus 로고
    • Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation
    • Landesberg R, Roy M, Glickman RS. Quantification of growth factor levels using a simplified method of platelet-rich plasma gel preparation. J Oral Maxillofacial Surg. 2000;58:297-300.
    • (2000) J Oral Maxillofacial Surg , vol.58 , pp. 297-300
    • Landesberg, R.1    Roy, M.2    Glickman, R.S.3
  • 11
    • 0035679001 scopus 로고    scopus 로고
    • Treatment of leg ulcers in beta-thalassaemia intermedia: Use of platelet-derived wound healing factors from the patient's own platelets
    • Gilsanz F, Escalante F, Auray C, et al. Treatment of leg ulcers in beta-thalassaemia intermedia: Use of platelet-derived wound healing factors from the patient's own platelets. Brit J Haematol. 2001;115:710.
    • (2001) Brit J Haematol , vol.115 , pp. 710
    • Gilsanz, F.1    Escalante, F.2    Auray, C.3
  • 12
    • 0031172191 scopus 로고    scopus 로고
    • Cytokine mRNA expression in human platelets and a megakaryocytic cell line and cytokine modulation of platelet function
    • Soslau G, Morgan DA, Jaffe JS, et al. Cytokine mRNA expression in human platelets and a megakaryocytic cell line and cytokine modulation of platelet function. Cytokine. 1997;9:405-11.
    • (1997) Cytokine , vol.9 , pp. 405-411
    • Soslau, G.1    Morgan, D.A.2    Jaffe, J.S.3
  • 13
    • 0032875460 scopus 로고    scopus 로고
    • Mechanism of action and in vivo role of platelet-derived growth factor
    • Heldin CH, Westermark B. Mechanism of action and in vivo role of platelet-derived growth factor. Physiolog Revs. 1999;79:1283-316.
    • (1999) Physiolog Revs , vol.79 , pp. 1283-1316
    • Heldin, C.H.1    Westermark, B.2
  • 14
    • 0034989658 scopus 로고    scopus 로고
    • Developmental roles of platelet-derived growth factors
    • Betsholtz C, Karlsson L, Lindahl P. Developmental roles of platelet-derived growth factors. Bioessays. 2001;23:494-507.
    • (2001) Bioessays , vol.23 , pp. 494-507
    • Betsholtz, C.1    Karlsson, L.2    Lindahl, P.3
  • 15
    • 0035821988 scopus 로고    scopus 로고
    • Evidence that human cardiac myocytes divide after myocardial infarction
    • Beltrami AP, Urbanek K, Kajstura J, et al. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med. 2001;344:1750-7.
    • (2001) N Engl J Med , vol.344 , pp. 1750-1757
    • Beltrami, A.P.1    Urbanek, K.2    Kajstura, J.3
  • 16
    • 0035746320 scopus 로고    scopus 로고
    • Changes in the IGF-IGFBP axis in critical illness
    • Baxter RC. Changes in the IGF-IGFBP axis in critical illness. Best Pract Res Clin Endocrinol Metab. 2001;15:421-34.
    • (2001) Best Pract Res Clin Endocrinol Metab , vol.15 , pp. 421-434
    • Baxter, R.C.1
  • 17
    • 7844242243 scopus 로고    scopus 로고
    • Acute cardiovascular effects of insulin-like growth factor I in patients with chronic heart failure
    • Donath MY, Sutsch G, Yan XW, et al. Acute cardiovascular effects of insulin-like growth factor I in patients with chronic heart failure. J Clin Endocrinol Metab. 1998;83:3177-83.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3177-3183
    • Donath, M.Y.1    Sutsch, G.2    Yan, X.W.3
  • 18
    • 0036127649 scopus 로고    scopus 로고
    • Beyond mitomycin: TGF-beta and wound healing
    • Cordeiro MF. Beyond mitomycin: TGF-beta and wound healing. Prog Retinal Eye Res. 2002;21:75-89.
    • (2002) Prog Retinal Eye Res , vol.21 , pp. 75-89
    • Cordeiro, M.F.1
  • 19
    • 0036615594 scopus 로고    scopus 로고
    • TGF-beta 1 regulates TGF-beta 1 and FGF-2 mRNA expression during fibroblast wound healing
    • Song QH, Klepeis VE, Nugent MA, et al. TGF-beta 1 regulates TGF-beta 1 and FGF-2 mRNA expression during fibroblast wound healing. J Clin Pathol-Molec Pathol. 2002;55:164-76.
    • (2002) J Clin Pathol-Molec Pathol , vol.55 , pp. 164-176
    • Song, Q.H.1    Klepeis, V.E.2    Nugent, M.A.3
  • 20
    • 0032142834 scopus 로고    scopus 로고
    • Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart
    • Sun Y, Zhang JQ, Zhang J, et al. Angiotensin II, transforming growth factor-beta1 and repair in the infarcted heart. J Mol Cell Cardiol. 1998;30:1559-69.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 1559-1569
    • Sun, Y.1    Zhang, J.Q.2    Zhang, J.3
  • 21
    • 0036126317 scopus 로고    scopus 로고
    • Increased levels of transforming growth factor-beta 1 in essential hypertension
    • Derhaschnig U, Shehata M, Herkner H, et al. Increased levels of transforming growth factor-beta 1 in essential hypertension. Am J Hypertens. 2002;15:207-11.
    • (2002) Am J Hypertens , vol.15 , pp. 207-211
    • Derhaschnig, U.1    Shehata, M.2    Herkner, H.3
  • 22
    • 0036599845 scopus 로고    scopus 로고
    • The role of growth factors in the repair of bone-Biology and clinical applications
    • Lieberman JR, Daluiski A, Einhorn TA. The role of growth factors in the repair of bone-Biology and clinical applications. J Bone Joint Surg - American Volume. 2002;84A:1032-44.
    • (2002) J Bone Joint Surg - American Volume , vol.84 A , pp. 1032-1044
    • Lieberman, J.R.1    Daluiski, A.2    Einhorn, T.A.3
  • 23
    • 0031766406 scopus 로고    scopus 로고
    • Potential role of fibroblast growth factor in enhancement of fracture healing
    • Radomsky ML, Thompson AY, Spiro RC, et al. Potential role of fibroblast growth factor in enhancement of fracture healing. Clin Orthopaed Related Res. 1998;355:S283-93.
    • (1998) Clin Orthopaed Related Res , vol.355
    • Radomsky, M.L.1    Thompson, A.Y.2    Spiro, R.C.3
  • 24
    • 0036670342 scopus 로고    scopus 로고
    • Short-term administration of basic fibroblast growth factor enhances coronary collateral development without exacerbating atherosclerosis and balloon injury-induced vasoproliferation in atherosclerotic rabbits with acute myocardial infarction
    • Zhang CX, Yang J, Feng JZ, et al. Short-term administration of basic fibroblast growth factor enhances coronary collateral development without exacerbating atherosclerosis and balloon injury-induced vasoproliferation in atherosclerotic rabbits with acute myocardial infarction. J Lab Clin Med. 2002;140:119-25.
    • (2002) J Lab Clin Med , vol.140 , pp. 119-125
    • Zhang, C.X.1    Yang, J.2    Feng, J.Z.3
  • 25
    • 0035448963 scopus 로고    scopus 로고
    • Cytokines, growth factors, and plastic surgery
    • Rumalla VK, Borah GL. Cytokines, growth factors, and plastic surgery. Plastic Reconstruct Surg. 2001;108:719-33.
    • (2001) Plastic Reconstruct Surg , vol.108 , pp. 719-733
    • Rumalla, V.K.1    Borah, G.L.2
  • 26
    • 0037016733 scopus 로고    scopus 로고
    • Differences in sensitivity of biological functions mediated by epidermal growth factor receptor activation with respect to endogenous and exogenous ligands
    • Sawhney RS, Zhou GHK, Humphrey LE, et al. Differences in sensitivity of biological functions mediated by epidermal growth factor receptor activation with respect to endogenous and exogenous ligands. J Biolog Chem. 2002;277:75-86.
    • (2002) J Biolog Chem , vol.277 , pp. 75-86
    • Sawhney, R.S.1    Zhou, G.H.K.2    Humphrey, L.E.3
  • 27
    • 0028908119 scopus 로고
    • The cellular basis of dilated cardiomyopathy in humans
    • Beltrami CA, Finato N, Rocco M, et al. The cellular basis of dilated cardiomyopathy in humans. J Molec Cellu Cardiol. 1995;27:291-305.
    • (1995) J Molec Cellu Cardiol , vol.27 , pp. 291-305
    • Beltrami, C.A.1    Finato, N.2    Rocco, M.3
  • 28
    • 0035821988 scopus 로고    scopus 로고
    • Evidence that human cardiac myocytes divide after myocardial infarction
    • Beltrami AP, Urbanek K, Kajstura J, et al. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med. 2001;344:1750-7.
    • (2001) N Engl J Med , vol.344 , pp. 1750-1757
    • Beltrami, A.P.1    Urbanek, K.2    Kajstura, J.3
  • 29
    • 0032584132 scopus 로고    scopus 로고
    • Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-Similarities to astrocyte grafts
    • Azizi SA, Stokes D, Augelli BJ, et al. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-Similarities to astrocyte grafts. Proc Natl Acad Sci USA. 1998;95:3908-13.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3908-3913
    • Azizi, S.A.1    Stokes, D.2    Augelli, B.J.3
  • 30
    • 0034532106 scopus 로고    scopus 로고
    • Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow
    • Mezey E, Chandross KJ, Harta G, et al. Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow. Science. 2000;290:1779-82.
    • (2000) Science , vol.290 , pp. 1779-1782
    • Mezey, E.1    Chandross, K.J.2    Harta, G.3
  • 31
    • 0032489651 scopus 로고    scopus 로고
    • Muscle regeneration by bone marrow-derived myogenic progenitors
    • Ferrari G, Cusella-De Angelis G, Coletta M, et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science. 1998;279:1528-30.
    • (1998) Science , vol.279 , pp. 1528-1530
    • Ferrari, G.1    Cusella-De Angelis, G.2    Coletta, M.3
  • 32
    • 0033598374 scopus 로고    scopus 로고
    • Dystrophin expression in the mdx mouse restored by stem cell transplantation
    • Gussoni E, Soneoka Y, Strickland CD, et al. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature. 1999;401:390-4.
    • (1999) Nature , vol.401 , pp. 390-394
    • Gussoni, E.1    Soneoka, Y.2    Strickland, C.D.3
  • 33
    • 0033553591 scopus 로고    scopus 로고
    • Bone marrow as a potential source of hepatic oval cells
    • Petersen BE, Bowen WC, Patrene KD, et al. Bone marrow as a potential source of hepatic oval cells. Science. 1999;284:1168-70.
    • (1999) Science , vol.284 , pp. 1168-1170
    • Petersen, B.E.1    Bowen, W.C.2    Patrene, K.D.3
  • 34
    • 0344672626 scopus 로고    scopus 로고
    • Autologous transplantation of bone marrow cells improves damaged heart function
    • Tomita S, Li RK, Weisel RD, et al. Autologous transplantation of bone marrow cells improves damaged heart function. Circulation. 1999;100:II247-56.
    • (1999) Circulation , vol.100
    • Tomita, S.1    Li, R.K.2    Weisel, R.D.3
  • 35
    • 0033002773 scopus 로고    scopus 로고
    • Myoblast cell grafting into heart muscle: Cellular biology and potential applications
    • Kessler PD, Byrne BJ. Myoblast cell grafting into heart muscle: Cellular biology and potential applications. Ann Rev Physiol. 1999;61:219-42.
    • (1999) Ann Rev Physiol , vol.61 , pp. 219-242
    • Kessler, P.D.1    Byrne, B.J.2
  • 36
    • 0035810240 scopus 로고    scopus 로고
    • Bone marrow cells regenerate infarcted myocardium
    • Orlic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature. 2001;410:701-5.
    • (2001) Nature , vol.410 , pp. 701-705
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 37
    • 0034988491 scopus 로고    scopus 로고
    • Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells
    • Jackson KA, Majka SM, Wang H, et al. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest. 2001;107:1395-402.
    • (2001) J Clin Invest , vol.107 , pp. 1395-1402
    • Jackson, K.A.1    Majka, S.M.2    Wang, H.3
  • 38
    • 2042538384 scopus 로고    scopus 로고
    • Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice
    • Bittner RE, Schofer C, Weipoltshammer K, et al. Recruitment of bone-marrow-derived cells by skeletal and cardiac muscle in adult dystrophic mdx mice. Anat Embryol (Berl). 1999;199:391-6.
    • (1999) Anat Embryol (Berl) , vol.199 , pp. 391-396
    • Bittner, R.E.1    Schofer, C.2    Weipoltshammer, K.3
  • 39
    • 0032782848 scopus 로고    scopus 로고
    • Myofibroblasts. I. Paracrine cells important in health and disease
    • Powell DW, Mifflin RC, Valentich JD, et al. Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol. 1999;277: C1-9.
    • (1999) Am J Physiol , vol.277
    • Powell, D.W.1    Mifflin, R.C.2    Valentich, J.D.3
  • 40
    • 0024785843 scopus 로고
    • Activated platelets express II-1 activity
    • Hawrylowicz CM, Santoro SA, Platt FM, et al. Activated platelets express II-1 activity. J Immunol. 1989;143:4015-8.
    • (1989) J Immunol , vol.143 , pp. 4015-4018
    • Hawrylowicz, C.M.1    Santoro, S.A.2    Platt, F.M.3
  • 41
    • 0002491871 scopus 로고    scopus 로고
    • Proinflammatory cytokines
    • Paul W, ed. New York: Lippincott-Raven
    • Krakauer T, Vilcek J, Oppenheim J. Proinflammatory Cytokines. In: Fundamental Immunology. Paul W, ed. New York: Lippincott-Raven; 1999:775-811.
    • (1999) Fundamental Immunology , pp. 775-811
    • Krakauer, T.1    Vilcek, J.2    Oppenheim, J.3
  • 42
    • 0028117243 scopus 로고
    • Cytokine generation in stored platelet concentrates
    • Stack G, Snyder EL. Cytokine generation in stored platelet concentrates. Transfusion. 1994;34:20-5.
    • (1994) Transfusion , vol.34 , pp. 20-25
    • Stack, G.1    Snyder, E.L.2
  • 43
    • 0034447646 scopus 로고    scopus 로고
    • The 3T3-L1 fibroblast to adipocyte conversion is accompanied by increased expression of angiopoietin-1, a ligand for Tie2
    • Stacker SA, Runting AS, Caesar C, et al. The 3T3-L1 fibroblast to adipocyte conversion is accompanied by increased expression of angiopoietin-1, a ligand for Tie2. Growth Factors. 2000;18:177-91.
    • (2000) Growth Factors , vol.18 , pp. 177-191
    • Stacker, S.A.1    Runting, A.S.2    Caesar, C.3
  • 44
    • 0034695685 scopus 로고    scopus 로고
    • The hemostatic system as a regulator of angiogenesis
    • Browder T, Folkman J, Pirie-Shepherd S. The hemostatic system as a regulator of angiogenesis. J Biolog Chem. 2000;275:1521-4.
    • (2000) J Biolog Chem , vol.275 , pp. 1521-1524
    • Browder, T.1    Folkman, J.2    Pirie-Shepherd, S.3
  • 45
    • 0036616886 scopus 로고    scopus 로고
    • IL-4 and interferon-gamma differentially modulate vascular endothelial growth factor release from normal human keratinocytes and fibroblasts
    • Trompezinski S, Denis A, Vinche A, et al. IL-4 and interferon-gamma differentially modulate vascular endothelial growth factor release from normal human keratinocytes and fibroblasts. Experiment Dermatol. 2002;11:224-31.
    • (2002) Experiment Dermatol , vol.11 , pp. 224-231
    • Trompezinski, S.1    Denis, A.2    Vinche, A.3
  • 46
    • 0035673503 scopus 로고    scopus 로고
    • Platelet chemokines and their receptors: What is their relevance to platelet storage and transfusion practice?
    • Boehlen F, Clemetson KJ. Platelet chemokines and their receptors: What is their relevance to platelet storage and transfusion practice? Transfus Med. 2001;11:403-17.
    • (2001) Transfus Med , vol.11 , pp. 403-417
    • Boehlen, F.1    Clemetson, K.J.2
  • 48
    • 0033064552 scopus 로고    scopus 로고
    • Differential induction of monocyte chemotactic protein-3 in mononuclear leukocytes and fibroblasts by interferon-alpha/beta and interferon-gamma reveals MCP-3 heterogeneity
    • Menten P, Proost P, Struyf S, et al. Differential induction of monocyte chemotactic protein-3 in mononuclear leukocytes and fibroblasts by interferon-alpha/beta and interferon-gamma reveals MCP-3 heterogeneity. Euro J Immunol. 1999;29:678-85.
    • (1999) Euro J Immunol , vol.29 , pp. 678-685
    • Menten, P.1    Proost, P.2    Struyf, S.3
  • 49
    • 0036372456 scopus 로고    scopus 로고
    • Prostanoid signal integration and cross talk
    • Wise H, Wong YH, Jones RL. Prostanoid signal integration and cross talk. Neurosignals. 2002;11:20-8
    • (2002) Neurosignals , vol.11 , pp. 20-28
    • Wise, H.1    Wong, Y.H.2    Jones, R.L.3
  • 50
    • 85160900493 scopus 로고    scopus 로고
    • Stimulation of angiotensin converting enzyme by transforming growth factor-beta (1) in rat cardiac fibroblasts
    • Petrov V, Fagard RH, Lijnen P. Stimulation of angiotensin converting enzyme by transforming growth factor-beta (1) in rat cardiac fibroblasts. J Hypertens. 2000;18;S123-4.
    • (2000) J Hypertens , vol.18
    • Petrov, V.1    Fagard, R.H.2    Lijnen, P.3


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