메뉴 건너뛰기




Volumn 34, Issue 12, 2002, Pages 1577-1584

Molecular mechanisms of myocardial remodeling. The role of aldosterone

Author keywords

Aldosterone; Cardiac remodeling; Evolutionary medicine; Fibrosis; Heart failure; Myocardial infarction; Renin angiotensin system

Indexed keywords

ALDOSTERONE; ALDOSTERONE RECEPTOR; ANGIOTENSIN 2 RECEPTOR; CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; LOSARTAN; SPIRONOLACTONE; TRANSCRIPTION FACTOR;

EID: 0036911129     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2002.2088     Document Type: Review
Times cited : (153)

References (51)
  • 2
    • 0001095307 scopus 로고
    • Myocardial chemo-mechanical energy transduction
    • HA Fozzard, E Haber, AM Katz, R Jennings. H Morgan (ed.). New York: Raven Press
    • Alpert NR, Mulieri LA, Hasenfuss G. Myocardial chemo-mechanical energy transduction. In: HA Fozzard, E Haber, AM Katz, R Jennings. H Morgan (ed.) The Heart and Cardiovascular System 1992. New York: Raven Press, 111-128.
    • (1992) The Heart and Cardiovascular System , pp. 111-128
    • Alpert, N.R.1    Mulieri, L.A.2    Hasenfuss, G.3
  • 3
    • 0032949682 scopus 로고    scopus 로고
    • Molecular mechanisms of myocardial remodeling
    • Swynghedauw B. Molecular mechanisms of myocardial remodeling. Physiol Rev 1999, 79, 215-262.
    • (1999) Physiol Rev , vol.79 , pp. 215-262
    • Swynghedauw, B.1
  • 5
    • 0035818917 scopus 로고    scopus 로고
    • Aldosterone on congestive heart failure
    • Weber KT, Aldosterone on congestive heart failure. N Engl J Med 2001; 345: 1689-1697.
    • (2001) N Engl J Med , vol.345 , pp. 1689-1697
    • Weber, K.T.1
  • 7
    • 0025989761 scopus 로고
    • 2+ATPase and calsequestrine genes in rat heart during ontogenic development and ageing
    • 2+ATPase and calsequestrine genes in rat heart during ontogenic development and ageing. Circ Res 1991; 69: 1380-1388.
    • (1991) Circ Res , vol.69 , pp. 1380-1388
    • Lompré, A.M.1    Lambert, F.2    Lakatta, E.G.3    Schwartz, K.4
  • 13
    • 0024459457 scopus 로고
    • Coregulation of calcium channels and beta-adrenergic receptors in cultured chick embryo ventricular ceils
    • Marsh JD. Coregulation of calcium channels and beta-adrenergic receptors in cultured chick embryo ventricular ceils. J Clin Invest 1989; 84: 817-823.
    • (1989) J Clin Invest , vol.84 , pp. 817-823
    • Marsh, J.D.1
  • 14
    • 0343081008 scopus 로고    scopus 로고
    • 2+ current in adult rat cardiomyocytes
    • 2+ current in adult rat cardiomyocytes. Circ Res 1999; 85: 1139-1145.
    • (1999) Circ Res , vol.85 , pp. 1139-1145
    • Benitah, J.P.1    Vassort, G.2
  • 15
    • 0025675680 scopus 로고
    • Remodeling of the rat right and left ventricles in experimental hypertension
    • Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT. Remodeling of the rat right and left ventricles in experimental hypertension. Circ Res 1990; 67: 1355-1364.
    • (1990) Circ Res , vol.67 , pp. 1355-1364
    • Brilla, C.G.1    Pick, R.2    Tan, L.B.3    Janicki, J.S.4    Weber, K.T.5
  • 17
    • 0028785677 scopus 로고
    • Determinants of cardiac fibrosis in experimental hypermineralocorticoid states
    • Young M, Head G, Funder J. Determinants of cardiac fibrosis in experimental hypermineralocorticoid states. Am J Physiol 1995; 269: E657-E662.
    • (1995) Am J Physiol , vol.269
    • Young, M.1    Head, G.2    Funder, J.3
  • 20
    • 0028275578 scopus 로고
    • Collagen metabolism in cultured adult rat cardiac fibroblasts: Response to angiotensin II and aldosterone
    • Brilla CG, Zhou G, Matsubara L, Weber KT. Collagen metabolism in cultured adult rat cardiac fibroblasts: Response to angiotensin II and aldosterone. J Mol Cell Cardiol 1994; 26: 809-820.
    • (1994) J Mol Cell Cardiol , vol.26 , pp. 809-820
    • Brilla, C.G.1    Zhou, G.2    Matsubara, L.3    Weber, K.T.4
  • 21
    • 85047676796 scopus 로고
    • Aldosterone and cardiac fibrosis: In vitro studies
    • Fullerton MJ, Funder JW. Aldosterone and cardiac fibrosis: In vitro studies. Cardiovasc Res 1994; 28: 1863-1867.
    • (1994) Cardiovasc Res , vol.28 , pp. 1863-1867
    • Fullerton, M.J.1    Funder, J.W.2
  • 22
    • 0032996757 scopus 로고    scopus 로고
    • Cardiac fibrosis and inflammation: Interaction with hemodynamic and hormonal factors
    • Nicoletti A, Michel JB. Cardiac fibrosis and inflammation: Interaction with hemodynamic and hormonal factors. Cardiovasc Res 1999; 41: 532-543.
    • (1999) Cardiovasc Res , vol.41 , pp. 532-543
    • Nicoletti, A.1    Michel, J.B.2
  • 23
    • 0027314849 scopus 로고
    • Myocardial fibrosis in the rat with mineralocorticoid excess. Prevetion of scarring by amiloride
    • Campbell SE, Janicki JS, Matsubara BB, Weber KT. Myocardial fibrosis in the rat with mineralocorticoid excess. Prevetion of scarring by amiloride. Am J Hypert 1993; 6: 487-495.
    • (1993) Am J Hypert , vol.6 , pp. 487-495
    • Campbell, S.E.1    Janicki, J.S.2    Matsubara, B.B.3    Weber, K.T.4
  • 24
    • 0032588244 scopus 로고    scopus 로고
    • Angiotensin AT1 receptor subtype as a cardiac target of aldosterone. Role in aldosterone-salt induced fibrosis
    • Robert V, Heymes C, Silvestre JS, Sabri A, Swynghedauw B, Delcayre C, Angiotensin AT1 receptor subtype as a cardiac target of aldosterone. Role in aldosterone-salt induced fibrosis. Hypertension 1999; 33: 981-986.
    • (1999) Hypertension , vol.33 , pp. 981-986
    • Robert, V.1    Heymes, C.2    Silvestre, J.S.3    Sabri, A.4    Swynghedauw, B.5    Delcayre, C.6
  • 25
    • 0029690592 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme and wound healing in diverse tissues of the rat
    • Sun Y, Weber KT. Angiotensin-converting enzyme and wound healing in diverse tissues of the rat. J Lab Clin Med 1996; 127: 94-101.
    • (1996) J Lab Clin Med , vol.127 , pp. 94-101
    • Sun, Y.1    Weber, K.T.2
  • 26
    • 0028862412 scopus 로고
    • Increased endothelin-1 gene expression in the endothelium of coronary arteries and endocardium in the DOCA-salt hypertensive rat
    • Lariviere R, Deng LY, DAY R et al. Increased endothelin-1 gene expression in the endothelium of coronary arteries and endocardium in the DOCA-salt hypertensive rat. J Mol Cell Cardiol 1995; 27: 2123-2131.
    • (1995) J Mol Cell Cardiol , vol.27 , pp. 2123-2131
    • Lariviere, R.1    Deng, L.Y.2    Day, R.3
  • 27
    • 0000685149 scopus 로고    scopus 로고
    • Aldosterone regulates collagen output of cardiac fibroblasts by upregulation of endothelin receptors
    • Fullerton MJ, Funder JW, Aldosterone regulates collagen output of cardiac fibroblasts by upregulation of endothelin receptors. Endocrin Soc Proc 1998; 93: 511.
    • (1998) Endocrin Soc Proc , vol.93 , pp. 511
    • Fullerton, M.J.1    Funder, J.W.2
  • 28
    • 12244295338 scopus 로고
    • Bradykinin receptor and tissue ACE binding in myocardial fibrosis: Response to chronic angiotensin II administration: Attenuation by calcium channel blockade
    • Sun Y, Ratajska A, Weber KT. Bradykinin receptor and tissue ACE binding in myocardial fibrosis: Response to chronic angiotensin II administration: Attenuation by calcium channel blockade. J Mol Cell Cardiol 1995; 30: 475-483.
    • (1995) J Mol Cell Cardiol , vol.30 , pp. 475-483
    • Sun, Y.1    Ratajska, A.2    Weber, K.T.3
  • 29
    • 0032031528 scopus 로고    scopus 로고
    • Myocardial fibrosis associated with aldosterone or angiotensin II administration: Attenuation bt calcium channel blockade
    • Ramires FJA, Sun Y, Weber KT. Myocardial fibrosis associated with aldosterone or angiotensin II administration: Attenuation bt calcium channel blockade. J Mol Cell Cardiol 1998; 30: 475-483.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 475-483
    • Ramires, F.J.A.1    Sun, Y.2    Weber, K.T.3
  • 30
    • 0029914353 scopus 로고    scopus 로고
    • Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats
    • Karam H, Heudes D, Hess P; Gonzales MF, Löffler BM, Clozel JP. Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats. Cardiovasc Res 1996; 31: 287-295.
    • (1996) Cardiovasc Res , vol.31 , pp. 287-295
    • Karam, H.1    Heudes, D.2    Hess, P.3    Gonzales, M.F.4    Löffler, B.M.5    Clozel, J.P.6
  • 31
    • 0029897702 scopus 로고    scopus 로고
    • Angiotensin II-induced myocardial fibrosis in rats: Role of nitric oxide, prostaglandins and bradykinin
    • Sigusch HH, Campbell SE, Weber KT. Angiotensin II-induced myocardial fibrosis in rats: Role of nitric oxide, prostaglandins and bradykinin. Cardiovasc Res 1996; 31: 546-554.
    • (1996) Cardiovasc Res , vol.31 , pp. 546-554
    • Sigusch, H.H.1    Campbell, S.E.2    Weber, K.T.3
  • 32
  • 33
    • 0026692172 scopus 로고
    • Aldosterone regulation of gene transcription leading to control of ion transport
    • Horisberger JD, Rossier BC. Aldosterone regulation of gene transcription leading to control of ion transport. Hypertension 1992; 19: 221-227.
    • (1992) Hypertension , vol.19 , pp. 221-227
    • Horisberger, J.D.1    Rossier, B.C.2
  • 35
    • 0030737574 scopus 로고    scopus 로고
    • Aldosterone rapidly represses protein kinase C activity in neonatal rat cardiomyocytes in vitro
    • Sato A, Liu JP, Funder JW. Aldosterone rapidly represses protein kinase C activity in neonatal rat cardiomyocytes in vitro. Endocrinology 1997, 138: 3410-3416.
    • (1997) Endocrinology , vol.138 , pp. 3410-3416
    • Sato, A.1    Liu, J.P.2    Funder, J.W.3
  • 37
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. N Engl J Med 1999; 341:709-717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 38
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure
    • Zannad F, Alla F, Dousset B, Perez A, Pitt B. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure. Circulation 2000; 102: 2700-2706.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3    Perez, A.4    Pitt, B.5
  • 39
    • 0035168937 scopus 로고    scopus 로고
    • Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after myocardial infarction
    • Modena MG, Aveta P, Menozzi A, Rossi R. Aldosterone inhibition limits collagen synthesis and progressive left ventricular enlargement after myocardial infarction. AM Heart J 2001; 141: 41-46.
    • (2001) AM Heart J , vol.141 , pp. 41-46
    • Modena, M.G.1    Aveta, P.2    Menozzi, A.3    Rossi, R.4
  • 40
    • 0030870613 scopus 로고    scopus 로고
    • Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients
    • MacFayden RJ, Barr CS, Struthers AD. Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients. Cardiovasc Res 1997; 35: 30-34.
    • (1997) Cardiovasc Res , vol.35 , pp. 30-34
    • MacFayden, R.J.1    Barr, C.S.2    Struthers, A.D.3
  • 42
    • 0034681831 scopus 로고    scopus 로고
    • Gene expression in the distinct regions of the heart
    • Thum T, Borlak J. Gene expression in the distinct regions of the heart. Lancet 2000; 355: 979-983.
    • (2000) Lancet , vol.355 , pp. 979-983
    • Thum, T.1    Borlak, J.2
  • 43
    • 0030838414 scopus 로고    scopus 로고
    • Compartimentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces
    • Dell'Italia LI, Meng QC, Balcells E, Wei CC, Palmer R, Hageman GR, Durand J, Hankes GH, Oparil S. Compartimentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces. J Clin Invest 1997; 100: 253-258.
    • (1997) J Clin Invest , vol.100 , pp. 253-258
    • Dell'Italia, L.I.1    Meng, Q.C.2    Balcells, E.3    Wei, C.C.4    Palmer, R.5    Hageman, G.R.6    Durand, J.7    Hankes, G.H.8    Oparil, S.9
  • 48
    • 0034585189 scopus 로고    scopus 로고
    • Recruitable ACE and tissue repair in the infarcted heart
    • Weber KT. Recruitable ACE and tissue repair in the infarcted heart. J Renin Angio Aldo System 2000; 1: 295-303.
    • (2000) J Renin Angio Aldo System , vol.1 , pp. 295-303
    • Weber, K.T.1
  • 49
    • 0017806658 scopus 로고
    • Perinatal chages in plasma and adrenal corticosterone and aldosterone concentrations in the mouse
    • Dalle M, Giry J, Gay M. Delost P. Perinatal chages in plasma and adrenal corticosterone and aldosterone concentrations in the mouse. J Endocr 1978; 76: 303-309.
    • (1978) J Endocr , vol.76 , pp. 303-309
    • Dalle, M.1    Giry, J.2    Gay, M.3    Delost, P.4
  • 50
    • 0031013606 scopus 로고    scopus 로고
    • Expression of cytochromes P450ado and P45011beta in rat adrenal gland durinlate gestational and neonatal stages
    • Mitani F, Mukai K, Ogawa T, Miyamoto H, Ishimura Y. Expression of cytochromes P450ado and P45011beta in rat adrenal gland durinlate gestational and neonatal stages. Steroids 1997; 62: 57-61.
    • (1997) Steroids , vol.62 , pp. 57-61
    • Mitani, F.1    Mukai, K.2    Ogawa, T.3    Miyamoto, H.4    Ishimura, Y.5
  • 51
    • 0031790388 scopus 로고    scopus 로고
    • Development of adrenal zonation in fetal rats defined by expression of aldosterone synthase and 11beta-hydroxylase
    • Wotus C, Levay-Young BK, Rogers LM, Gomez-Sanchez CE, Engeland WC. Development of adrenal zonation in fetal rats defined by expression of aldosterone synthase and 11beta-hydroxylase. Endocrinology 1998; 139: 4397-4403.
    • (1998) Endocrinology , vol.139 , pp. 4397-4403
    • Wotus, C.1    Levay-Young, B.K.2    Rogers, L.M.3    Gomez-Sanchez, C.E.4    Engeland, W.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.