Proteomic analysis of neuronal hypoxia in vitro

Neurochemical Research

Volumn 29, Issue 6, 2004, Pages 1123-1128

  Jin, K ^a   Mao, X O ^a   Greenberg, D A ^a  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

Author keywords

Activity regulated cytoskeleton associated protein; Cytoskeleton; Hypoxia; Neurogenesis; Neuron; Proteomics

Indexed keywords

ACETYLCHOLINESTERASE; ACTIVITY REGULATED CYTOSKELETON ASSOCIATED PROTEIN; DOUBLECORTIN; DOUBLECORTIN CALMODULIN KINASE LIKE 1 PROTEIN; ENDOTHELIAL MONOCYTE ACTIVATING POLYPEPTIDE II; ERYTHROCYTE BAND 4.9 PROTEIN; FIBRONECTIN; FK 506 BINDING PROTEIN; HS1 ASSOCIATED PROTEIN X 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NUCLEAR AUTOANTIGENIC SPERM PROTEIN; P160 RHOA BINDING KINASE; PAXILLIN; PHOSPHOLIPASE C; PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN) IV; PROTEIN KINASE C RELATED KINASE 2; PROTEIN TYROSINE KINASE; RAS GAP ASSOCIATED PROTEIN; RAS RELATED PROTEIN 1; STRIATIN; TRANSCRIPTION FACTOR E2F1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; NERVE PROTEIN; PROTEOME;

ANIMAL CELL; ANIMAL MODEL; CELL HYPOXIA; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; EMBRYO; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; REVIEW; UPREGULATION; WESTERN BLOTTING; ANIMAL; ARTICLE; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEWBORN; PHYSIOLOGY;

ANIMALIA;

ANIMALS; ANIMALS, NEWBORN; CELL HYPOXIA; CELLS, CULTURED; CYTOSKELETAL PROTEINS; GENE EXPRESSION REGULATION; MICE; NERVE TISSUE PROTEINS; NEURONS; PROTEOME;

EID: 3142726151     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000023599.88356.7b     Document Type: Review

References (64)

1. Hochachka, P. W. 1986. Defense strategies against hypoxia and hypothermia. Science 231:234-241.
2. Powell, F. L. 2003. Functional genomics and the comparative physiology of hypoxia. Annu. Rev. Physiol. 65:203-230.
3. Goldberg, M. A., Dunning, S. P., and Bunn, H. F. 1988. Regulation of the erythropoietin gene: evidence that the oxygen sensor is a heme protein. Science 242:1412-1415.
4. Shweiki, D., Itin, A., Soffer, D., and Keshet, E. 1992. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845.
5. Shimizu, S., Eguchi, Y., Kosaka, H., Kamiike, W., Matsuda, H., and Tsujimoto, Y. 1995. Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL. Nature 374:811-813.
6. Jin, K., Mao, X. O., Sun, Y., Xie, L., and Greenberg, D. A. 2002. Stem cell factor stimulates neurogenesis in vitro and in vivo. J. Clin. Invest. 110:311-319.
7. Jin, K., Zhu, Y., Sun, Y., Mao, X. O., Xie, L., and Greenberg, D. A. 2002. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc. Natl. Acad. Sci. USA 99:11946-11950.
8. Burmester, T., Weich, B., Reinhardt, S., and Hankein, T. 2000. A vertebrate globin expressed in the brain. Nature 407:520-523.
9. Sun, Y., Jin, K., Mao, X. O., Zhu, Y., and Greenberg, D. A. 2001. Neuroglobin is upregulated by and protects neurons from hypoxicischemic injury. Proc. Natl. Acad. Sci. USA 98:15306-15311.
10. Miyamoto, O. and Auer, R. N. 2000. Hypoxia, hyperoxia, ischemia, and brain necrosis. Neurology 54:362-371.
11. Bemaudin, M., Tang, Y., Reilly, M., Petit, E., and Sharp, F. R. 2002. Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance. J. Biol. Chem. 277:39728-39738.
12. Jin, K., Mao, X., Eshoo, M., del Rio, G., Rao, R., Chen, D., Simon, R., and Greenberg, D. 2002. cDNA microarray analysis of changes in gene expression induced by neuronal hypoxia. Neurochem. Res. 27:1105-1112.
13. Soriano, M. A., Tessier, M., Certa, U., and Gill, R. 2000. Parallel gene expression monitoring using oligonucleotide probe arrays of multiple transcripts with an animal model of focal ischemia. J. Cereb. Blood Flow Metab. 20:1045-1055.
14. Jin, K. L., Mao, X. O., Eshoo, M. W., Nagayama, T., Minami, M., Simon, R. P., and Greenberg, D. A. 2001. Microarray analysis of hippocampal gene expression in global cerebral ischemia. Ann. Neurol. 50:93-103.
15. Rohlff, C. 2000. Proteomics in molecular medicine: applications in central nervous systems disorders. Electrophoresis 21: 1227-1234.
16. Jin, K. L., Mao, X. O., and Greenberg, D. A. 2000. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc. Natl. Acad. Sci. USA 97:10242-10247.
17. Koretz, B., Ahem, K. v. B., Lusting, H. S., and Greenberg, D. A. 1994. Pre- and postsynaptic modulators of excitatory neurotransmission: comparative effects on hypoxia/hypoglycemia in cortical cultures. Brain Res. 643:334-337.
18. Yoo, G. H., Piechocki, M. P., Ensley, J. F., Nguyen, T., Oliver, J., Meng, H., Kewson, D., Shibuya, T. Y., Lonardo, F., and Tainsky, M. A. 2002. Docetaxel induced gene expression patterns in head and neck squamous cell carcinoma using cDNA microarray and PowerBlot. Clin. Cancer Res. 8:3910-3921.
19. Malakhov, M. P., Kim, K. I., Malakhova, O. A., Jacobs, B. S., Borden, E. C., and Zhang, D. E. 2003. High-throughput immunoblotting: ubiquitin-like protein ISG15 modifies key regulators of signal transduction. J. Biol. Chem. 10.1074/jbc. M208435200.
20. Eyford, G. E., Yamagata, K., Kaufmann, W. E., Barnes, C. A., Sanders, E. K., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Eanahan, A. A., and Worley, P. F. 1995. Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. Neuron 14:433-445.
21. Steward, O. and Worley, P. F. 2001. A cellular mechanism for targeting newly synthesized mRNAs to synaptic sites on dendrites. Proc. Natl. Acad. Sci. USA 98:7062-7068.
22. Dong, E., Caruncho, H., Liu, W. S., Smalheiser, N. R., Grayson, D. R., Costa, E., and Guidotti, A. 2003. A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes. Proc. Natl. Acad. Sci. USA 100:5479-5484.
23. Pei, Q., Lewis, E., Sprakes, M. E., Jones, E. J., Grahame-Smith, D. G., and Zetterstrom, T. S. 2000. Serotonergic regulation of mRNA expression of Arc, an immediate early gene selectively localized at neuronal dendrites. Neuropharmacology 39:463-470.
24. Kremerskothen, J., Wendholt, D., Teber, I., and Barnekow, A. 2002. Insulin-induced expression of the activity-regulated cytoskeleton-associated gene (ARC) in human neuroblastoma cells requires p21(ras), mitogen-activated protein kinase/extracellular regulated kinase and src tyrosine kinases but is protein kinase C-independent. Neurosci. Lett. 321:153-156.
25. Ying, S. W., Futter, M., Rosenblum, K., Webber, M. J., Hunt, S. P., Bliss, T. V., and Bramham, C. R. 2002. Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis. J. Neurosci. 22:1532-1540.
26. Kunizuka, H., Kinouchi, H., Arai, S., Izaki, K., Mikawa, S., Kamii, H., Sugawara, T., Suzuki, A., Mizoi, K., and Yoshimoto, T. 1999. Activation of Arc gene, a dendritic immediate early gene, by middle cerebral artery occlusion in rat brain. Neuroreport 10:1717-1722.
27. Ginsberg, S. D., Hemby, S. E., Eee, V. M., Eberwine, J. H., and Trojanowski, J. Q. 2000. Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons. Ann. Neurol. 48:77-87.
28. Burgess, H. A. and Reiner, O. 2001. Cleavage of doublecortin-like kinase by calpain releases an active kinase fragment from a microtubule anchorage domain. J. Biol. Chem. 276:36397-36403.
29. Lin, P. T., Gleeson, J. G., Corbo, J. C., Flanagan, E., and Walsh, C. A. 2000. DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization. J. Neurosci. 20:9152-9161.
30. Burgess, H. A. and Reiner, O. 2000. Doublecortin-like kinase is associated with microtubules in neuronal growth cones. Mol. Cell. Neurosci. 16:529-541.
31. Burgess, H. A., Martinez, S., and Reiner, O. 1999. KIAA0369, doublecortin-like kinase, is expressed during brain development. J. Neurosci. Res. 58:567-575.
32. Mizuguchi, M., Qin, J., Yamada, M., Ikeda, K., and Takashima, S. 1999. High expression of doublecortin and KIAA0369 protein in fetal brain suggests their specific role in neuronal migration. Am. J. Pathol. 155:1713-1721.
33. Hirsch, E., Gullberg, D., Balzac, F., Altruda, F., Silengo, L., and Tarone, G. 1994. Alpha v integrin subunit is predominantly located in nervous tissue and skeletal muscle during mouse development. Dev. Dyn. 201:108-120.
34. Anton, E. S., Kreidberg, J. A., and Rakic, P. 1999. Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migration and laminar organization of the cerebral cortex. Neuron 22:277-289.
35. Chao, C. C., Ma, Y. L., Chu, K. Y., and Lee, E. H. 2003. Integrin alphav and NCAM mediate the effects of GDNF on DA neuron survival, outgrowth, DA turnover and motor activity in rats. Neurobiol. Aging 24:105-116.
36. Rogers, S. L., McCarthy, J. B., Palm, S. L., Furcht, L. T., and Letourneau, P. C. 1985. Neuron-specific interactions with two neurite-promoting fragments of fibronectin. J. Neurosci. 5: 369-378.
37. Yanaka, K., Camarata, P. J., Spellman, S. R., McCarthy, J. B., Furcht, L. T., Low, W. C., and Heros, R. C. 1996. Synthetic fibronectin peptides and ischemic brain injury after transient middle cerebral artery occlusion in rats. J. Neurosurg. 85:125-130.
38. Sakai, T., Johnson, K. J., Murozono, M., Sakai, K., Magnuson, M. A., Wieloch, T., Cronberg, T., Isshiki, A., Erickson, H. P., and Fassler, R. 2001. Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis. Nat. Med. 7:324-330.
39. Tate, M. C., Shear, D. A., Hoffman, S. W., Stein, D. G., Archer, D. R., and LaPlaca, M. C. 2002. Fibronectin promotes survival and migration of primary neural stem cells transplanted into the traumatically injured mouse brain. Cell Transplant. 11: 283-295.
40. Schetinger, M. R., Bonan, C. D., Frassetto, S. S., Wyse, A. T., Schierholt, R. C., Webber, A., Dias, R. D., Sarkis, J. J., and Netto, C. A. 1999. Pre-conditioning to global cerebral ischemia changes hippocampal acetylcholinesterase in the rat. Biochem. Mol. Biol. Int. 47:473-478.
41. Tanaka, K., Mizukawa, K., Ogawa, N., and Mori, A. 1995. Post-ischemic administration of the acetylcholinesterase inhibitor ENA-713 prevents delayed neuronal death in the gerbil hippocampus. Neurochem. Res. 20:663-667.
42. Maekawa, M., Ishizaki, T., Boku, S., Watanabe, N., Fujita, A., Iwamatsu, A., Obinata, T., Ohashi, K., Mizuno, K., and Narumiya, S. 1999. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 285: 895-898.
43. Sieber, F. E., Traystman, R. J., and Martin, L. J. 1997. Delayed neuronal death after global incomplete ischemia in dogs is accompanied by changes in phospholipase C protein expression. J. Cereb. Blood Flow Metab. 17:527-533.
44. Sharkey, J. and Butcher, S. P. 1994. Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischemia. Nature 371:336-339.
45. Wood, J. D., Yuan, I., Margolis, R. L., Colomer, V., Duan, K., Kushi, J., Kaminsky, Z., Kleiderlein, J. J., Sharp, A. H., and Ross, C. A. 1998. Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins. Mol. Cell. Neurosci. 11:149-160.
46. Hall, A. 1998. Rho GTPases and the actin cytoskeleton. Science 279:509-514.
47. Richardson, R. T., Batova, I. N., Widgren, E. E., Zheng, L. X., Whitfield, M., Marzluff, W. F., and O'Rand, M. G. 2000. Characterization of the histone H1-binding protein, NASP, as a cell cycle-regulated somatic protein. J. Biol. Chem. 275:30378-30386.
48. Zhu. Y., Jin, K., Mao, X., and Greenberg, D. 2003. Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression. FASEB J. 17:186-193.
49. Ha, H. C. and Snyder, S. H. 2000. Poly(ADP-ribose) polymerase-1 in the nervous system. Neurobiol. Dis. 7:225-239.
50. Magavi, S. S., Leavitt, B. R., and Macklis, J. D. 2000. Induction of neurogenesis in the neocortex of adult mice. Nature 405:951-955.
51. Koistinaho, J. and Hökfelt, T. 1997. Altered gene expression in brain ischemia. Neuroreport 8:i-viii.
52. Sharp, F. R., Lu, A., Tang, Y., and Millhorn, D. E. 2000. Multiple molecular penumbras after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 20:1011-1032.
53. Graham, S. H. and Chen, J. 2001. Programmed cell death in cerebral ischemia. J. Cereb. Blood Flow Metab. 21:99-109.
54. Siesjo, B. K. 1985. Oxygen deficiency and brain damage: localization, evolution in time, and mechanisms of damage. J. Toxicol. Clin. Toxicol. 23:267-280.
55. Fitzpatrick, M. O., Dewar, D., Teasdale, G. M., and Graham, D. I. 1998. The neuronal cytoskeleton in acute brain injury. Br. J. Neurosurg. 12:313-317.
56. Lipton, P. 1999. Ischemic cell death in brain neurons. Physiol. Rev. 79:1431-1568.
57. Bartus, R. T., Dean, R. L., Mennerick, S., Eveleth, D., and Lynch, G. 1998. Temporal ordering of pathogenic events following transient global ischemia. Brain Res. 790:1-13.
58. Liebetrau, M., Staufer, B., Auerswald, E. A., Gabrijelcic-Geiger, D., Fritz, H., Zimmermann, C., Pfefferkorn, T., and Hamann, G. F. 1999. Increased intracellular calpain detection in experimental focal cerebral ischemia. Neuroreport 10:529-534.
59. Friedman, J. E., Chow, E. J., and Haddad, G. G. 1998. State of actin filaments is changed by anoxia in cultured rat neocortical neurons. Neuroscience 82:421-427.
60. Stys, P. K. and Jiang, Q. 2002. Calpain-dependent neurofilament breakdown in anoxic and ischemic rat central axons. Neurosci. Lett. 328:150-154.
61. Bernstein. B. W. and Bamburg, J. R. 2003. Actin-ATP hydrolysis is a major energy drain for neurons. J. Neurosci. 23:1-6.
62. Bossenmeyer-Pourie, C., Lievre, V., Grojean, S., Koziel, V., Pillot, T., and Daval, J. L. 2002. Sequential expression patterns of apoptosis- and cell cycle-related proteins in neuronal response to severe or mild transient hypoxia. Neuroscience 114:869-882.
63. Waxman, S. G., Black, J. A., Ransom, B. R., and Stys, P. K. 1993. Protection of the axonal cytoskeleton in anoxic optic nerve by decreased extracellular calcium. Brain Res. 614:137-145.
64. Leone, J. and Ochs, S. 1978. Anoxic block and recovery of axoplasmic transport and electrical excitability of nerve. J. Neurobiol. 9:229-245.