Oral synthetic folic acid and vitamin B12 supplements work - If one consumes them

Nutrition Reviews

Volumn 62, Issue 6 I, 2004, Pages S22-S26

  Oakley Jr , Godfrey P ^a  

^a EMORY UNIVERSITY   (United States)

Author keywords

Dietary supplements; Folate; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; SYNTHETIC CYANOCOBALAMIN; SYNTHETIC FOLIC ACID; UNCLASSIFIED DRUG;

BIRTH DEFECT; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CONFERENCE PAPER; CYANOCOBALAMIN BLOOD LEVEL; DRUG EFFICACY; FLOUR; FOLIC ACID BLOOD LEVEL; FOOD FORTIFICATION; FOOD PROCESSING; HEALTH CARE ORGANIZATION; HUMAN; VITAMIN BLOOD LEVEL; VITAMIN INTAKE; VITAMIN SUPPLEMENTATION;

EID: 3142720494     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1753-4887.2004.tb00067.x     Document Type: Conference Paper

References (31)

1. Oakley GP Jr. Inertia on folic acid fortification: public health malpractice. Teratology. 2002;66:44-54.
2. Oakley GP. Delaying folic acid fortification of flour. BMJ. 2002;324:1348-1349.
3. Oakley G. Global prevention of all folic acid-preventable spina bifida and anencephaly by 2010. Commu Genet. 2002;5:70-77.
4. Honein MA, Paulozzi LJ, Mathews TJ, Erickson JD, Wong LY. Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. JAMA. 2001;285:2981-2986.
5. Persad VL, Van den Hof MC, Dube JM, Zimmer P. Incidence of open neural tube defects in Nova Scotia after folic acid fortification. CMAJ. 2002;167:241-245.
6. Lawrence JM, Petitti DB, Watkins M, Umekubo MA. Trends in serum folate after food fortification. Lancet. 1999;354:915-916.
7. Ray JG, Vermeulen MJ, Boss SC, Cole DE. Increased red cell folate concentrations in women of reproductive age after Canadian folic acid food fortification. Epidemiology. 2002;13:238-240.
8. Bostom AG, Selhub J, Jacques PF, Rosenberg IH. Power Shortage: clinical trials testing the "homocysteine hypothesis" against a background of folic acid-fortified cereal grain flour. Ann Intern Med. 2001;135:133-137.
9. Jacques PF, Selhub J, Bostom AG, Wilson PW, Rosenberg IH. The effect of folic acid fortification on plasma folate and total homocysteine concentrations. N Engl J Med. 1999;340:1449-1454.
10. Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ. 2002;325.
11. Freire WB, Hertrampf E, Cortes F. Effect of folic acid fortification in Chile: preliminary results. Eur J Pediatr Surg. 2000;10:42-43.
12. Centers for Disease Control and Prevention. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Morbid Mortal Wkly Rep. 1992;41:1-7.
13. Institute of Medicine. Dietary Reference Intake: folate, other B vitamins and choline. Institute of Medicine. Washington, DC: National Academy Press; 1998.
14. Food and Drug Administration. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Fed Regist. 1996;61:8781-8807.
15. MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group. Lancet. 1991;338:131-137.
16. Berry RJ, Li Z, Erickson JD, et al. Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention [corrected; erratum to be published]. N Engl J Med. 1999;341:1485-1490.
17. Raats M, Thorpe L, Hurren C, Elliott K. Changing Preconceptions: The HEA Folic Acid Campaign, 1995-1998. London, Health Education Authority; 1998.
18. De Walle HE, De Jong-Van Den Berg LT. Insufficient folic acid intake in the Netherlands: what about the future? Teratology. 2002;66:40-43.
19. Erickson JD. Folic acid and prevention of spina bifida and anencephaly. 10 years after the U.S. Public Health Service recommendation. MMWR Morbid Mortal Wkly Rept. 2002;51:1-3.
20. Than LC, Watkins M, Daniel KL. Serum folate levels among women attending family planning clinicsGeorgia, 2000. MMWR Morbid Mortal Wkly Rep. 2002;51:4-8.
21. de Bree A, Verschuren WM, Blom HJ, Kromhout D. Association between B vitamin intake and plasma homocysteine concentration in the general Dutch population aged 20-65 y. Am J Clin Nutr. 2001;73:1027-1033.
22. Selhub J, Jacques PF, Wilson PW, Rush D, Rosenberg IH. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. JAMA. 1993;270:2693-2698.
23. Lindenbaum J, Rosenberg IH, Wilson PW, Stabler SP, Allen RH. Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr. 1994;60:2-11.
24. Carmel R. Current concepts in cobalamin deficiency. Ann Rev Med. 2000;51:357-375.
25. Rajan S, Wallace J, I., Brodkin KJ, Beresford SA, Allen RH, Stabler SP. Response of elevated methylmalonic acid to three dose levels of roal cobalamin in older adults. J Am Geriatr Soc. 2002;50:1789-1795.
26. Boushey CJ, Beresford SA, Omenn GS, Motulsky AG. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA. 1995;274:1049-1057.
27. Tice JA, Ross E, Coxson PG, et al. Cost-effectiveness of vitamin therapy to lower plasma homocysteine levels for the prevention of coronary heart disease: effect of grain fortification and beyond. JAMA. 2001;286:936-943.
28. Mark SD, Wang W, Fraumeni JF, et al. Lowered risks of hypertension and cerebrovascular disease after vitamin/mineral supplementation: the Linxian Nutrition Intervention Trial. Am J Epidemiol. 1996;143:658-664.
29. Committee on Medical Aspects of Food and Nutrition Policy. Folic acid and the prevention of disease. Report of the committee on medical-aspects of food and nutrition policy. Reports on Health and Social Subjects. 2000;50:i-xv, 1-101.
30. Flood VM, Webb KL, Smith W, et al. Folate fortification: potential impact on folate intake in an older population. Eur J Clin Nutr. 2001;55:793-800.
31. Dickinson CJ. Does folic acid harm people with vitamin B12 deficiency? QJM. 1995;88:357-364.