Melatonin does not prevent the protection of ischemic preconditioning in vivo despite its antioxidant effect against oxidative stress

Free Radical Biology and Medicine

Volumn 37, Issue 4, 2004, Pages 500-510

  Andreadou, Ioanna ^a,b   Iliodromitis, Efstathios K ^a   Mikros, Emmanuel ^b   Bofilis, Elias ^a   Zoga, Anastasia ^a   Constantinou, Maria ^b   Tsantili Kakoulidou, Anna ^b   Kremastinos, Dimitrios T ^a  

^a ONASSIS CARDIAC SURGERY CENTER   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

4 HNE; 4 hydroxy nonenal; analysis of variance; ANOVA; Antioxidant; Carr Purcell Meiboom Gill; CPMG; FIDs; free induction decays; Free radicals; heart rate; HR; I R; Infarct size; Ischemia reperfusion; Ischemic preconditioning; Melatonin; Metabolic profile

Indexed keywords

ACETYLCYSTEINE; MELATONIN; SUPEROXIDE DISMUTASE;

ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; IN VIVO STUDY; LIPID PEROXIDATION; MALE; MOLECULAR SIZE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION;

ACETYLCYSTEINE; ALDEHYDES; ANIMALS; ANTIOXIDANTS; FREE RADICALS; ISCHEMIC PRECONDITIONING; LIPID PEROXIDATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MALONDIALDEHYDE; MELATONIN; MODELS, STATISTICAL; OXIDATIVE STRESS; RABBITS; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; TIME FACTORS;

ORYCTOLAGUS CUNICULUS;

EID: 3142530267     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.05.005     Document Type: Article

References (54)

1. Murry C.E., Jennings R.B., Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemia myocardium. Circulation. 74(5):1986;1124-1136
2. Schulz R., Cohen M.V., Behrends M., Downey J.M., Heusch G. Signal transduction of ischemic preconditioning. Cardiovasc. Res. 52:2001;181-198
3. Liu Y., Downey J.M. Ischemic preconditioning protects against infarction in rat heart. Am. J. Physiol. 263:1992;H1107-H1112
4. Heusch G. Nitroglycerin and delayed preconditioning in humans. Yet another new mechanism for an old drug? Circulation. 103:2001;2876-2878
5. Yellon D.M., Dana A. The preconditioning phenomenon. A tool for the scientist or a clinical reality? Circ. Res. 87:2000;543-550
6. Tritto I.D., Andrea D., Eramo N., Scognamiglio A., De Simone C., Violante A., Esposito A., Chiariello M., Ambrosio G. Oxygen radicals can induce preconditioning in rabbit hearts. Circ. Res. 80:1997;743-748
7. Skyschally A., Schulz R., Gres P., Korth H., Heusch G. Attenuation of ischemic preconditioning in pigs by scavenging of free oxyradicals with ascorbic acid. Am. J. Physiol. Heart Circ. Physiol. 284:2003;H698-H703
8. Steeves G., Singh N., Singal P.K. Preconditioning and antioxidant defense against reperfusion injury. Ann. NY Acad. Sci. 723:1994;116-127
9. Chen W., Gabel S., Steenbergen C., Murphy E. A redox-based mechanism for cardioprotection induced by ischemic preconditioning in perfused rat heart. Circ. Res. 77:1995;424-429
10. Pain T., Yang X., Critz S.D., Yue Y., Nakano A., Liu G.S., Heusch G., Cohen M.V., Downey J.M. Opening of mitochondrial K atp channels triggers the preconditioned state by generating free radicals. Circ. Res. 15:2000;460-466
11. Forbes R.A., Steenbergen C., Murphy E. The protective effect of diazoxide is blocked by antioxidants. Circulation. 100(Suppl. I):1999;I342. (Abstract)
12. Andreadou I., Tasouli A., Iliodromitis E., Tsantili-Kakoulidou A., Papalois A., Siatra T., Kremastinos D.T. Reduction of myocardial infarct size in rabbits by a novel indole derivative with antioxidant and free radical scavenging properties. Eur. J. Pharmacol. 453:2002;271-277
13. Downey J.M., Omar B., Ooiwa H., McCord J. Superoxide dismutase therapy for myocardial ischemia. Free Radic. Res. Commun. 2:1991;703-720
14. Brzezinski A. Melatonin in humans. N. Engl. J. Med. 336:1997;186
15. Reiter R.J., Melchiorri D., Sewerynck E., Poeggeler B., Barlow-Walden C., Chuag J., Ortiz G.G., Acuna-Castroviejo D. A review of the evidence supporting melatonins' role as an antioxidant. J. Pineal Res. 18:1995;1-11
16. Reiter R.J., Tang L., Garcia J.J., Munoz-Hoyos A. Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci. 60:1997;2255-2271
17. Pieri C., Marra M., Moroni F., Recchioni R., Marcheselli F. Melatonin: a peroxyl radical scavenger more effective than vitamin E. Life Sci. 55:1994;PL271-PL276
18. Lahiri D.K., Ghosh C. Interactions between melatonin, reactive oxygen species, and nitric oxide. Ann. NY Acad. Sci. 893:1999;325-330
19. Reiter R.J., Tan D.-X. Melatonin: a novel protective agent against oxidative injury of the ischemic reperfused heart. Cardiovasc. Res. 58:2003;10-19
20. Salie R., Harper I., Cillie C., Genade S., Huisamen B., Moolman J., Lochner A. Melatonin protects against ischemic-reperfusion myocardial damage. J. Mol. Cell. Cardiol. 33:2001;343-357
21. Lagneux C., Joyeux M., Demenge P., Ribuot C., Godin-Ribuot D. Protective effects of melatonin against ischemia-reperfusion injury in the isolated rat heart. Life Sci. 66:2000;503-509
22. Dave R.H., Hale S.L., Kloner R.A. The effect of melatonin on hemodynamics, blood flow, and myocardial infarct size in a rabbit model of ischemia-reperfusion. J. Cardiovasc. Pharmacol. Therapeut. 3(2):1998;153-160
23. Antolin I., Rodriquez C., Sainz R.M., Mayo J.C., Uria H., Kotler M.L., Rodriquez-Colunga M.J., Tolivia D., Menendez-Pelaez A. Neurohormone melatonin prevents cell damage: effect on gene expression for antioxidant enzymes. FASEB J. 10:1996;882-890
24. Espina J.R., Shockor J.P., Herron W.J., Car B.D., Contel N.R., Ciaccio P.J., Lindon J.C., Holmes E., Nicholson J.K. Detection of in vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches. Magn. Res. Chem. 39:2001;559-565
25. Iliodromitis E., Ktremastinos D.T., Katritsis D.G., Papadopoulos C.C., Hearse D.J. Multiple cycles of preconditioning cause loss of protection in open-chest rabbits. J. Mol. Cell. Cardiol. 29:1997;915-920
26. Tanaka K., Weihrauch D., Kehl F., Ludwig L.M., LaDisa J.F., Kersten J.R., Pagel P.S., Wartlier D.C. Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. Anesthesiology. 97:2002;1485-1490
27. Kremastinos D.T., Bofilis E., Karavolias G., Papalois A., Kaklamanis L., Iliodromitis E. Preconditioning limits myocardial infarct size in hypocholesterolemic rabbits. Atherosclerosis. 150:2000;81-89
28. Campo G.M., Squadrito F., Campo S., Altavilla D., Quartarone C., Ceccarelli S., Ferlito M., Avenoso A., Squadrito G., Saitta A., Caputi A.P. Beneficial effect of raxofelast, an hydrophilic vitamin E analogue, in the rat heart after ischemia and reperfusion injury. J. Mol. Cell. Cardiol. 30:1998;1493-1503
29. Esterbauer H., Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malondialdehyde and 4-hydroxynonenal. Methods Enzymol. 186:1990;407-421
30. Arthur J.R., Boyne L.R. Superoxide dismutase and glutathione peroxidase activities in neutrophils from selenium deficient and copper deficient cattle. Life Sci. 36:1985;1569-1575
31. 13C NMR spectroscopy of human blood plasma. Anal. Chem. 67:1995;793-811
32. Gavaghan C.L., Holmes E., Lenx E., Wilson I.D., Nicholson J.K. An NMR-based metabonomic approach to investigate the biochemical consequenses of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse. FEBS Lett. 484:2000;169-174
33. Miwa K., Igawa A., Nakagawa K., Hirai T., Inoue H. Consumption of vitamin E in coronary circulation in patients with variant angina. Cardiovasc. Res. 41:1999;291-298
34. Kugiyama K., Miyao Y., Sakamoto T., Kawano H., Soejima N., Miyamoto S., Yoshimura M., Ogawa H., Sugiyama S., Yasue H. Glutathione attenuates coronary constriction to acetylcholine in patients with coronary spastic angina. Am. J. Physiol. Heart Circ. Physiol. 280:2001;H264-H271
35. Shinmura K., Bolli R., Liu S.Q., Tang X.L., Kodani E., Xuan Y., Srivastava S., Bhatnagar A. Aldose reductase is an obligatory mediator of the late phase of ischemic preconditioning. Circ. Res. 91:2002;240-246
36. Schuster C., Gauer F., Malan A., Recio J., Pevet P., Masson-Pevet M. The circadian clock, light/dark cycle and melatonin are differentially involved in the expression of daily and photoperiodic variations in mt(1) melatonin receptors in the Siberian and Syrian hamsters. Neuroendocrinology. 74(1):2001;55-68
37. Doolen S., Krause D.N., Dubocovich M.L., Duckles S.P. Melatonin mediates two distinct responses in vascular smooth muscle. Eur. J. Pharmacol. 345(1):1998;67-69
38. Ram P.T., Dai J., Yuan L., Dong C., Kiefer T.L., Lai L., Hill S.M. Involvement of the mt(1) melatonin receptor in human breast cancer. Cancer Lett. 179(2):2002;141-150
39. Witt-Enderby P.A., Bennet J., Jarzynka M.J., Firestine S., Melan M.A. Melatonin receptors and their regulation: biochemical and structural mechanisms. Life Sci. 72:2003;2183-2198
40. Clemens J.W., Jarzynka M.J., Witt-Enderby P.A. Down regulation of mt1 melatonin receptors in rat ovary following estrogen exposure. Life Sci. 69:2001;27-35
41. Roth J.A., Kim B.G., Lin W.L., Cho M.I. Melatonin promotes osteoblast differentiation and bone formation. J. Biol. Chem. 274:1999;22041-22047
42. Baines C.P., Cohen M.V., Downey J.M. Signal transduction in ischemic preconditioning: the role of kinases and mitochondrial KATP channels. J. Cardiovasc. Electrophysiol. 10:1999;741-754
43. Hoek T.L.V., Becker L.B., Shao Z., Li C., Schumacker P.T. Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes. J. Biol. Chem. 273:1998;18092-18098
44. Hoek T.L.V., Becker L.B., Shao Z., Li C., Schumacker P.T. Preconditioning in cardiomyocytes protects by attenuating oxidant stress at reperfusion. Circ. Res. 86:2000;541-548
45. Das D.K., Maulik N., Sato M., Ray P.S. Reactive oxygen species function as second messenger during ischemic preconditioning of heart. Mol. Cell. Biochem. 196:1999;59-67
46. Zhou X., Zhai X., Ashraf M. Direct evidence that initial oxidative stress triggered by preconditioning contributes to second window of protection by endogenous antioxidant enzyme in myocytes. Circulation. 93:1996;1177-1184
47. Turrens J.F., Thornton J., Barnard M.L., Snyder S., Liu G., Downey J.M. Protection from reperfusion injury by preconditioning hearts does not involve increased antioxidant defenses. Am. J. Physiol. 262:1992;H585-H589
48. Tanaka M., Fujiwara H., Yamasaki K., Sasayama S. Superoxide dismutase and N-2-mercaptopropionyl glycine attenuate infarct size limitation effect of ischemic preconditioning in the rabbit. Cardiovasc. Res. 28:1994;980-986
49. Iwamoto T., Miura T., Adachi T., Noto T., Ogawa T., Tsuchida A., Iimura O. Myocardial infarct size-limiting effect of ischemic preconditioning was not attenuated by oxygen free radical scavengers in the rabbit. Circulation. 83:1991;1015-1022
50. Tan D.X., Manchester L.C., Reiter R.J., Qi W.B., Karbownik M., Calvo R.J. Significance of melatonin in antioxidative defense system: reactions and products. Biol. Signals Recept. 9:2000;137-159
51. Andreadou I., Tsantili-Kakoulidou A., Spyropoulou E., Siatra T. Reactions of indole derivatives with cardioprotective activity with reactive oxygen species. Comparison with melatonin. Chem. Pharm. Bull. 51:2003;1128-1131
52. Cohen M.C., Yang X.M., Liu G.S., Heush G., Downey J.M. Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial KATP channels. Circ. Res. 89:2001;273-278
53. Liu G.S., Thornton J., Van Winkle D.M., Stanley A.W., Olsson R.A., Downey J.M. Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart. Circulation. 84:1991;350-356
54. Sandhu R., Diaz R.J., Mao G.D., Wilson G.J. Ischemic preconditioning. Differences in protection and susceptibility to blockade with single-cycle versus multicycle transient ischemia. Circulation. 96:1997;984-995