Reduction of myocardial infarct size in rabbits by a novel indole derivative with antioxidant and free radical scavenging properties

European Journal of Pharmacology

Volumn 453, Issue 2-3, 2002, Pages 271-277

  Andreadou, Ioanna ^a   Tasouli, Androniki ^b   Iliodromitis, Efstathios ^b   Tsantili Kakoulidou, Anna ^a   Papalois, Apostolos ^c   Siatra, Theodora ^a   Kremastinos, Dimitrios Th ^b  

^a UNIVERSITY OF ATHENS   (Greece)

^b ONASSIS CARDIAC SURGERY CENTER   (Greece)

^c ELPEN Pharmaceuticals   (Greece)

Author keywords

Cardioprotection; Free radical scavenger; Indole derivative; Ischemia reperfusion; Malondialdehyde; Myocardial infarct size

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 3 [(1H 1 INDOYL)METHYL] 4 AMINO 4,5 DIHYDRO 1H,1,2,4 TRIAZOLE 5 THIONE; C 6458; FREE RADICAL; INDOLE DERIVATIVE; MALONALDEHYDE; MANNITOL; UNCLASSIFIED DRUG; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; 3 ((1H 1 INDOLYL)METHYL) 4 AMINO 4,5 DIHYDRO 1H,1,2,4 TRIAZOLE 5 THIONE; 3-((1H-1-INDOLYL)METHYL) -4-AMINO 4,5-DIHYDRO-1H,1,2,4 TRIAZOLE-5-THIONE; ANTIOXIDANT; DIMETHYL SULFOXIDE; HYDROXYL RADICAL; PICRIC ACID; SCAVENGER; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; HEART INFARCTION; HEART INFARCTION SIZE; HEART INJURY; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IN VITRO STUDY; MALE; MEASUREMENT; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REPERFUSION INJURY; SPECTROPHOTOMETRY; ANIMAL; BLOOD; CHEMISTRY; DOSE RESPONSE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; PATHOLOGY; RABBIT;

ANIMALS; ANTIOXIDANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIMETHYL SULFOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; FREE RADICALS; HEART INJURIES; HYDROXYL RADICAL; INDOLES; MALE; MALONDIALDEHYDE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; PICRATES; RABBITS; TRIAZOLES;

EID: 0037174827     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02431-7     Document Type: Article

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