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Volumn 176, Issue 3, 2006, Pages 1447-1455

Tumor-specific CD4+ T cells are activated by "cross-dressed" dendritic cells presenting peptide-MHC class II complexes acquired from cell-based cancer vaccines

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 31144469922     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.3.1447     Document Type: Article
Times cited : (81)

References (52)
  • 1
    • 12744253307 scopus 로고    scopus 로고
    • Sinks, suppressors and antigen presenters: How lymphodepletion enhances T cell-mediated tumor immunotherapy
    • Klebanoff, C. A., H. T. Khong, P. A. Antony, D. C. Palmer, and N. P. Restifo. 2005. Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy. Trends Immunol. 26: 111-117.
    • (2005) Trends Immunol. , vol.26 , pp. 111-117
    • Klebanoff, C.A.1    Khong, H.T.2    Antony, P.A.3    Palmer, D.C.4    Restifo, N.P.5
  • 2
    • 0141720783 scopus 로고    scopus 로고
    • Cancer vaccines: Between the idea and the reality
    • Finn, O. J. 2003. Cancer vaccines: between the idea and the reality. Nat. Rev. Immunol. 3: 630-641.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 630-641
    • Finn, O.J.1
  • 3
    • 17144417748 scopus 로고    scopus 로고
    • Dendritic cells as therapeutic vaccines against cancer
    • Banchereau, J., and A. K. Palucka. 2005. Dendritic cells as therapeutic vaccines against cancer. Nat. Rev. Immunol. 5: 296-306.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 296-306
    • Banchereau, J.1    Palucka, A.K.2
  • 4
    • 0027078670 scopus 로고
    • Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4
    • Chen, L., S. Ashe, W. A. Brady, I. Hellstrom, K. E. Hellstrom, J. A. Ledbetter, P. McGowan, and P. S. Linsley. 1992. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 71: 1093-1102.
    • (1992) Cell , vol.71 , pp. 1093-1102
    • Chen, L.1    Ashe, S.2    Brady, W.A.3    Hellstrom, I.4    Hellstrom, K.E.5    Ledbetter, J.A.6    McGowan, P.7    Linsley, P.S.8
  • 5
    • 0031572579 scopus 로고    scopus 로고
    • Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis
    • Daniel, P. T., A. Kroidl, S. Cayeux, R. Bargou, T. Blankenstein, and B. Dorken. 1997. Costimulatory signals through B7.1/CD28 prevent T cell apoptosis during target cell lysis. J. Immunol. 159: 3808-3815.
    • (1997) J. Immunol. , vol.159 , pp. 3808-3815
    • Daniel, P.T.1    Kroidl, A.2    Cayeux, S.3    Bargou, R.4    Blankenstein, T.5    Dorken, B.6
  • 6
    • 0027392843 scopus 로고
    • + T cells by B7-transfected melanoma cells
    • + T cells by B7-transfected melanoma cells. Science 259: 368-370.
    • (1993) Science , vol.259 , pp. 368-370
    • Townsend, S.E.1    Allison, J.P.2
  • 7
    • 0028934350 scopus 로고
    • Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 Costimulatory molecules
    • Yang, G., K. E. Hellstrom, I. Hellstrom, and L. Chen. 1995. Antitumor immunity elicited by tumor cells transfected with B7-2, a second ligand for CD28/CTLA-4 Costimulatory molecules. J. Immunol. 154: 2794-2800.
    • (1995) J. Immunol. , vol.154 , pp. 2794-2800
    • Yang, G.1    Hellstrom, K.E.2    Hellstrom, I.3    Chen, L.4
  • 8
    • 0031569119 scopus 로고    scopus 로고
    • Influence of gene-modified (IL-7, IL-4, and B7) tumor cell vaccines on tumor antigen presentation
    • Cayeux, S., G. Richter, G. Noffz, B. Dorken, and T. Blankenstein. 1997. Influence of gene-modified (IL-7, IL-4, and B7) tumor cell vaccines on tumor antigen presentation. J. Immunol. 158: 2834-2841.
    • (1997) J. Immunol. , vol.158 , pp. 2834-2841
    • Cayeux, S.1    Richter, G.2    Noffz, G.3    Dorken, B.4    Blankenstein, T.5
  • 11
    • 0025299735 scopus 로고
    • Rejection of mouse sarcoma cells after transfection of MHC class II genes
    • Ostrand-Rosenberg, S., A. Thakur, and V. Clements. 1990. Rejection of mouse sarcoma cells after transfection of MHC class II genes. J. Immunol. 144: 4068-4071.
    • (1990) J. Immunol. , vol.144 , pp. 4068-4071
    • Ostrand-Rosenberg, S.1    Thakur, A.2    Clements, V.3
  • 12
    • 0032053794 scopus 로고    scopus 로고
    • Reduction of established spontaneous mammary carcinoma metastases following immunotherapy with major histocompatibility complex class II and B7.1 cell-based tumor vaccines
    • Pulaski, B. A., and S. Ostrand-Rosenberg. 1998. Reduction of established spontaneous mammary carcinoma metastases following immunotherapy with major histocompatibility complex class II and B7.1 cell-based tumor vaccines. Cancer Res. 58: 1486-1493.
    • (1998) Cancer Res. , vol.58 , pp. 1486-1493
    • Pulaski, B.A.1    Ostrand-Rosenberg, S.2
  • 16
    • 0034669908 scopus 로고    scopus 로고
    • Tumor cells present MHC class II-restricted nuclear and mitochondrial antigens and are the predominant antigen presenting cells in vivo
    • Qi, L., J. M. Rojas, and S. Ostrand-Rosenberg. 2000. Tumor cells present MHC class II-restricted nuclear and mitochondrial antigens and are the predominant antigen presenting cells in vivo. J. Immunol. 165: 5451-5461.
    • (2000) J. Immunol. , vol.165 , pp. 5451-5461
    • Qi, L.1    Rojas, J.M.2    Ostrand-Rosenberg, S.3
  • 19
    • 0030921106 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity
    • Armstrong, T. D., V. K. Clements, B. K. Martin, J. P. Ting, and S. Ostrand-Rosenberg. 1997. Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity. Proc. Natl. Acad. Sci. USA 94: 6886-6891.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6886-6891
    • Armstrong, T.D.1    Clements, V.K.2    Martin, B.K.3    Ting, J.P.4    Ostrand-Rosenberg, S.5
  • 21
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 22
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman, R. M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9: 271-296.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 25
    • 0033946489 scopus 로고    scopus 로고
    • + tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon-γ
    • + tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon-γ. Cancer Immunol. Immunother. 49: 34-45.
    • (2000) Cancer Immunol. Immunother. , vol.49 , pp. 34-45
    • Pulaski, B.A.1    Clements, V.K.2    Pipeling, M.R.3    Ostrand-Rosenberg, S.4
  • 26
    • 0030000166 scopus 로고    scopus 로고
    • Expression of MHC class II and B7-1 and B7-2 costimulatory molecules accompanies tumor rejection and reduces the metastatic potential of tumor cells
    • Ostrand-Rosenberg, S., S. Baskar, N. Patterson, and V. K. Clements. 1996. Expression of MHC class II and B7-1 and B7-2 costimulatory molecules accompanies tumor rejection and reduces the metastatic potential of tumor cells. Tissue Antigens 47: 414-421.
    • (1996) Tissue Antigens , vol.47 , pp. 414-421
    • Ostrand-Rosenberg, S.1    Baskar, S.2    Patterson, N.3    Clements, V.K.4
  • 27
    • 0024514569 scopus 로고
    • T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas
    • Johnson, N. A., F. Carland, P. M. Allen, and L. H. Glimcher. 1989. T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas. J. Immunol. 142: 3298-3304.
    • (1989) J. Immunol. , vol.142 , pp. 3298-3304
    • Johnson, N.A.1    Carland, F.2    Allen, P.M.3    Glimcher, L.H.4
  • 28
    • 0027180010 scopus 로고
    • Processing of endogenously synthesized hen egg-white lysozyme retained in the endoplasmic reticulum or in secretory form gives rise to a similar but not identical set of epitopes recognized by class II-restricted T cells
    • Adorini, L., J. C. Guery, S. Fuchs, V. Ortiz-Navarrete, G. J. Hammerling, and F. Momburg. 1993. Processing of endogenously synthesized hen egg-white lysozyme retained in the endoplasmic reticulum or in secretory form gives rise to a similar but not identical set of epitopes recognized by class II-restricted T cells. J. Immunol. 151: 3576-3586.
    • (1993) J. Immunol. , vol.151 , pp. 3576-3586
    • Adorini, L.1    Guery, J.C.2    Fuchs, S.3    Ortiz-Navarrete, V.4    Hammerling, G.J.5    Momburg, F.6
  • 30
    • 1642536489 scopus 로고    scopus 로고
    • Invariant chain and the MHC class II cytoplasmic domains regulate localization of MHC class II molecules to lipid rafts in tumor cell-based vaccines
    • Dolan, B. P., T. P. Phelan, D. Ilkovitch, L. Qi, W. F. Wade, T. M. Laufer, and S. Ostrand-Rosenberg. 2004. Invariant chain and the MHC class II cytoplasmic domains regulate localization of MHC class II molecules to lipid rafts in tumor cell-based vaccines. J. Immunol. 172: 907-914.
    • (2004) J. Immunol. , vol.172 , pp. 907-914
    • Dolan, B.P.1    Phelan, T.P.2    Ilkovitch, D.3    Qi, L.4    Wade, W.F.5    Laufer, T.M.6    Ostrand-Rosenberg, S.7
  • 31
    • 0022592927 scopus 로고
    • 402AX teratocarcinoma MHC class 1 antigen expression is regulated in vivo by Lyt 1, Lyt 2, and L3T4 expressing splenic T cells
    • Ostrand-Rosenberg, S., V. Clements, and L. Marr. 1986. 402AX teratocarcinoma MHC class 1 antigen expression is regulated in vivo by Lyt 1, Lyt 2, and L3T4 expressing splenic T cells. Cell. Immunol. 98: 257-265.
    • (1986) Cell. Immunol. , vol.98 , pp. 257-265
    • Ostrand-Rosenberg, S.1    Clements, V.2    Marr, L.3
  • 32
    • 11844277698 scopus 로고    scopus 로고
    • Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
    • Sinha, P., V. K. Clements, and S. Ostrand-Rosenberg. 2005. Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J. Immunol. 174: 636-645.
    • (2005) J. Immunol. , vol.174 , pp. 636-645
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3
  • 33
    • 0034139669 scopus 로고    scopus 로고
    • MHC class II presentation of endogenous tumor antigen by cellular vaccines depends on the endocytic pathway but not H2-M
    • Qi, L., and S. Ostrand-Rosenberg. 2000. MHC class II presentation of endogenous tumor antigen by cellular vaccines depends on the endocytic pathway but not H2-M. Traffic 1: 152-160.
    • (2000) Traffic , vol.1 , pp. 152-160
    • Qi, L.1    Ostrand-Rosenberg, S.2
  • 34
    • 0035869278 scopus 로고    scopus 로고
    • Dendritic cells acquire antigens from live cells for cross-presentation to CTL
    • Harshyne, L. A., S. C. Watkins, A. Gambotto, and S. M. Barratt-Boyes. 2001. Dendritic cells acquire antigens from live cells for cross-presentation to CTL. J. Immunol. 166: 3717-3723.
    • (2001) J. Immunol. , vol.166 , pp. 3717-3723
    • Harshyne, L.A.1    Watkins, S.C.2    Gambotto, A.3    Barratt-Boyes, S.M.4
  • 37
    • 0037369603 scopus 로고    scopus 로고
    • A role for class a scavenger receptor in dendritic cell nibbling from live cells
    • Harshyne, L. A., M. I. Zimmer, S. C. Watkins, and S. M. Barratt-Boyes. 2003. A role for class A scavenger receptor in dendritic cell nibbling from live cells. J. Immunol. 170: 2302-2309.
    • (2003) J. Immunol. , vol.170 , pp. 2302-2309
    • Harshyne, L.A.1    Zimmer, M.I.2    Watkins, S.C.3    Barratt-Boyes, S.M.4
  • 38
  • 41
    • 0037443410 scopus 로고    scopus 로고
    • Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo
    • Skokos, D., H. G. Botros, C. Demeure, J. Morin, R. Peronet, G. Birkenmeier, S. Boudaly, and S. Mecheri. 2003. Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo. J. Immunol. 170: 3037-3045.
    • (2003) J. Immunol. , vol.170 , pp. 3037-3045
    • Skokos, D.1    Botros, H.G.2    Demeure, C.3    Morin, J.4    Peronet, R.5    Birkenmeier, G.6    Boudaly, S.7    Mecheri, S.8
  • 42
    • 0017126775 scopus 로고
    • Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay
    • Bevan, M. J. 1976. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143: 1283-1288.
    • (1976) J. Exp. Med. , vol.143 , pp. 1283-1288
    • Bevan, M.J.1
  • 43
    • 0035059416 scopus 로고    scopus 로고
    • Cross-presentation, dendritic cells, tolerance and immunity
    • Heath, W. R., and F. R. Carbone. 2001. Cross-presentation, dendritic cells, tolerance and immunity. Annu. Rev. Immunol. 19: 47-64.
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 47-64
    • Heath, W.R.1    Carbone, F.R.2
  • 44
    • 0032717299 scopus 로고    scopus 로고
    • MHC class II molecules transferred between allogeneic dendritic cells stimulate primary mixed leukocyte reactions
    • Bedford, P., K. Garner, and S. C. Knight. 1999. MHC class II molecules transferred between allogeneic dendritic cells stimulate primary mixed leukocyte reactions. Int. Immunol. 11: 1739-1744.
    • (1999) Int. Immunol. , vol.11 , pp. 1739-1744
    • Bedford, P.1    Garner, K.2    Knight, S.C.3
  • 47
    • 10744229153 scopus 로고    scopus 로고
    • Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells
    • Andre, F., N. Chaput, N. E. Schartz, C. Flament, N. Aubert, J. Bernard, F. Lemonnier, G. Raposo, B. Escudier, D. H. Hsu, et al. 2004. Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J. Immunol. 172: 2126-2136.
    • (2004) J. Immunol. , vol.172 , pp. 2126-2136
    • Andre, F.1    Chaput, N.2    Schartz, N.E.3    Flament, C.4    Aubert, N.5    Bernard, J.6    Lemonnier, F.7    Raposo, G.8    Escudier, B.9    Hsu, D.H.10
  • 49
    • 0035883073 scopus 로고    scopus 로고
    • Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression
    • Sotomayor, E. M., I. Borrello, F. M. Rattis, A. G. Cuenca, J. Abrams, K. Staveley-O'Carroll, and H. I. Levitsky. 2001. Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression. Blood 98: 1070-1077.
    • (2001) Blood , vol.98 , pp. 1070-1077
    • Sotomayor, E.M.1    Borrello, I.2    Rattis, F.M.3    Cuenca, A.G.4    Abrams, J.5    Staveley-O'Carroll, K.6    Levitsky, H.I.7
  • 50
    • 0042470540 scopus 로고    scopus 로고
    • Does the immune system see tumors as foreign or self?
    • Pardoll, D. 2003. Does the immune system see tumors as foreign or self? Annu. Rev. Immunol. 21: 807-839.
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 807-839
    • Pardoll, D.1
  • 51
    • 0037196549 scopus 로고    scopus 로고
    • Multiple roles of the invariant chain in MHC class II function
    • Stumptner-Cuvelette, P., and P. Benaroch. 2002. Multiple roles of the invariant chain in MHC class II function. Biochim. Biophys. Acta 1542: 1-13.
    • (2002) Biochim. Biophys. Acta , vol.1542 , pp. 1-13
    • Stumptner-Cuvelette, P.1    Benaroch, P.2
  • 52
    • 3142681616 scopus 로고    scopus 로고
    • Dissection of the HLA-DR4 peptide repertoire in endocrine epithelial cells: Strong influence of invariant chain and HLA-DM expression on the nature of ligands
    • Muntasell, A., M. Carrascal, I. Alvarez, L. Serradell, P. van Veelen, F. A. Verreck, F. Koning, J. Abian, and D. Jaraquemada. 2004. Dissection of the HLA-DR4 peptide repertoire in endocrine epithelial cells: strong influence of invariant chain and HLA-DM expression on the nature of ligands. J. Immunol. 173: 1085-1093.
    • (2004) J. Immunol. , vol.173 , pp. 1085-1093
    • Muntasell, A.1    Carrascal, M.2    Alvarez, I.3    Serradell, L.4    Van Veelen, P.5    Verreck, F.A.6    Koning, F.7    Abian, J.8    Jaraquemada, D.9


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