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Volumn 85, Issue SUPPL. 5, 2005, Pages 20-24

Ezetimibe - Pharmacokinetics and therapeutics;Ezetimiba - Farmacocinética e terapêutica

Author keywords

Ezetimibe; Metabolism; Statin

Indexed keywords

CARRIER PROTEIN; COLESTIPOL; DRUG METABOLITE; EZETIMIBE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 31144460863     PISSN: 0066782X     EISSN: 16784170     Source Type: Journal    
DOI: 10.1590/S0066-782X2005002400006     Document Type: Review
Times cited : (3)

References (53)
  • 2
    • 0034332715 scopus 로고    scopus 로고
    • Evidence that tryglicerides are an independent coronary risk factor
    • Cullen P. Evidence that tryglicerides are an independent coronary risk factor. Am J Cardiol 2000;86:943-9
    • (2000) Am J Cardiol , vol.86 , pp. 943-949
    • Cullen, P.1
  • 3
    • 0034496618 scopus 로고    scopus 로고
    • HDL-chooesterol as a marker of coronary heart disease risk: The Québec cardiovascular study
    • Després JP,lemieux I, Daganais GR, et al.HDL-chooesterol as a marker of coronary heart disease risk: the Québec cardiovascular study. Atherosclerosis 2000; 153: 263-72
    • (2000) Atherosclerosis , vol.153 , pp. 263-272
    • Després, J.P.1    Lemieux, I.2    Daganais, G.R.3
  • 4
    • 0035910051 scopus 로고    scopus 로고
    • Influence of low high-density lipoprotein cholesterol and elevated triglycerides in coronary heart disease events and response to simvastatin therapy in 4S
    • For the Scandinavian Simvastatin Survival Study (4S) Group
    • Ballantyne C, Olsson AG, Cook TJ, Mercuri M, Pedersen T, Kjekshus J. For the Scandinavian Simvastatin Survival Study (4S) Group. Influence of low high-density lipoprotein cholesterol and elevated triglycerides in coronary heart disease events and response to simvastatin therapy in 4S. Circulation 2001;104:3046-3051.
    • (2001) Circulation , vol.104 , pp. 3046-3051
    • Ballantyne, C.1    Olsson, A.G.2    Cook, T.J.3    Mercuri, M.4    Pedersen, T.5    Kjekshus, J.6
  • 5
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary artery disease
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary artery disease. Lancet 1994; 344: 1383-9
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 6
    • 0033914187 scopus 로고    scopus 로고
    • Follow-up study of patients randomized in the Scandinavian Simvastatin Survival Study (4S) of cholesterol lowering
    • Pedersen TR, Wilhelmsen L, Faergeman O, et al. Follow-up study of patients randomized in the Scandinavian Simvastatin Survival Study (4S) of cholesterol lowering.Am J Cardiol 2000; 86: 257-62
    • (2000) Am J Cardiol , vol.86 , pp. 257-262
    • Pedersen, T.R.1    Wilhelmsen, L.2    Faergeman, O.3
  • 7
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of cholesterol levels
    • The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of cholesterol levels. N Engl J Med 1998; 339: 1349-57
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 8
    • 0037140177 scopus 로고    scopus 로고
    • The LIPID Study Group: Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: The LIPID trial follow-up
    • The LIPID Study Group: Long-term effectiveness and safety of pravastatin in 9014 patients with coronary heart disease and average cholesterol concentrations: the LIPID trial follow-up. Lancet 2002; 359: 1379-87
    • (2002) Lancet , vol.359 , pp. 1379-1387
  • 9
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20.536 high-risk individuals a randomized placebo controlled trial
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20.536 high-risk individuals a randomized placebo controlled trial. Lancet 2002; 360: 7-22
    • (2002) Lancet , vol.360 , pp. 7-22
  • 10
    • 10744225301 scopus 로고    scopus 로고
    • Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trial
    • Nissen SE, Tuzcu EM, Schoenhagen P, Brown BG, Ganz P, Vogel RA, Crowe T, Howard G, Cooper CJ, Brodie B, et al; REVERSAL Investigators. Effect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trial. JAMA. 2004;291:1071-1080
    • (2004) JAMA , vol.291 , pp. 1071-1080
    • Nissen, S.E.1    Tuzcu, E.M.2    Schoenhagen, P.3    Brown, B.G.4    Ganz, P.5    Vogel, R.A.6    Crowe, T.7    Howard, G.8    Cooper, C.J.9    Brodie, B.10
  • 11
    • 0032032592 scopus 로고    scopus 로고
    • Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study)
    • Jones P, Kafonek S, Laurora I, Hunninghake D. Comparative dose efficacy study of atorvastatin versus simvastatin, pravastatin, lovastatin, and fluvastatin in patients with hypercholesterolemia (the CURVES study). Am J Cardiol. 1998;81:582-587
    • (1998) Am J Cardiol , vol.81 , pp. 582-587
    • Jones, P.1    Kafonek, S.2    Laurora, I.3    Hunninghake, D.4
  • 12
    • 4143055661 scopus 로고    scopus 로고
    • Update on Statins: 2003
    • C. J. Vaughan and A. M. Gotto Jr. Update on Statins: 2003. Circulation,. 2004; 110(7): 886-892
    • (2004) Circulation , vol.110 , Issue.7 , pp. 886-892
    • Vaughan, C.J.1    Gotto Jr., A.M.2
  • 14
    • 0010829299 scopus 로고    scopus 로고
    • III Diretrizes Brasileiras sobre Dislipidemias e Diretrizes de Prevenção da Aterosclerose da Sociedade Brasileira de Cardiologia
    • III Diretrizes Brasileiras sobre Dislipidemias e Diretrizes de Prevenção da Aterosclerose da Sociedade Brasileira de Cardiologia. Arq. Bras. Cardiol. 2001; 77 (supl III): 1- 48
    • (2001) Arq. Bras. Cardiol. , vol.77 , Issue.3 SUPPL. , pp. 1-48
  • 15
    • 3142729178 scopus 로고    scopus 로고
    • Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
    • Grundy S.M; Cleeman J.I.; Merz C.N.B.; Brewer H.B; Clark L.T.; Hunninghake D.B.; Pasternak R.C.; Smith S.C.; Stone N.J; for the Coordinating Committee of the National Cholesterol Education Program, Endorsed by the National Heart, Lung, and Blood Institute, American College of Cardiology Foundation, and American Heart Association. Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation. 2004; 110: 227-239.
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.B.3    Brewer, H.B.4    Clark, L.T.5    Hunninghake, D.B.6    Pasternak, R.C.7    Smith, S.C.8    Stone, N.J.9
  • 16
    • 0038755662 scopus 로고    scopus 로고
    • Perspectives in Cholesterol-Lowering Therapy: The Role of Ezetimibe, a New Selective Inhibitor of Intestinal Cholesterol Absorption
    • Bruckert E, Giral P, Tellier P. Perspectives in Cholesterol-Lowering Therapy: The Role of Ezetimibe, a New Selective Inhibitor of Intestinal Cholesterol Absorption. Circulation. 2003; 107: 3124-3128.
    • (2003) Circulation , vol.107 , pp. 3124-3128
    • Bruckert, E.1    Giral, P.2    Tellier, P.3
  • 17
    • 0034937093 scopus 로고    scopus 로고
    • Lifestyle and risk factor management and use of drug therapies in coronary patients from 15 countries: Principal results from EUROASPIRE II
    • EUROASPIRE II Group. Lifestyle and risk factor management and use of drug therapies in coronary patients from 15 countries: principal results from EUROASPIRE II. Eur Heart J. 2001; 22: 554-572.
    • (2001) Eur Heart J , vol.22 , pp. 554-572
  • 18
    • 0036917270 scopus 로고    scopus 로고
    • Statins do no meet expectations for lowering lipoprotein cholesterol levels when used in clinical practice
    • Frolkis JP, Pearce GL, Nambi V, et al. Statins do no meet expectations for lowering lipoprotein cholesterol levels when used in clinical practice. Am J Med. 2002; 113: 625-629.
    • (2002) Am J Med , vol.113 , pp. 625-629
    • Frolkis, J.P.1    Pearce, G.L.2    Nambi, V.3
  • 19
    • 0347511008 scopus 로고    scopus 로고
    • Macrophages, inflammation, and atherosclerosis
    • Linton MF, Fazio S, Macrophages, inflammation, and atherosclerosis. Inter J Obesity (2003) 27, S35-S40.
    • (2003) Inter J Obesity , vol.27
    • Linton, M.F.1    Fazio, S.2
  • 20
    • 0242490816 scopus 로고    scopus 로고
    • Pharmacotherapy for dyslipidaemia - Current therapies and future agents
    • Bays H; Stein EA. Pharmacotherapy for dyslipidaemia - current therapies and future agents. Expert Opinion on Pharmacotherapy 2003, vol. 4, no. 11, pp. 1901 - 1938
    • (2003) Expert Opinion on Pharmacotherapy , vol.4 , Issue.11 , pp. 1901-1938
    • Bays, H.1    Stein, E.A.2
  • 21
    • 0038823934 scopus 로고    scopus 로고
    • Ezetimibe for Management of Hypercholesterolemia
    • Vicent FM; Tuckerman E.C. Ezetimibe for Management of Hypercholesterolemia. Ann Pharmacother. 2003;37:839-48
    • (2003) Ann Pharmacother , vol.37 , pp. 839-848
    • Vicent, F.M.1    Tuckerman, E.C.2
  • 22
    • 0037255303 scopus 로고    scopus 로고
    • Pharmacology of the ACAT inhibitor avasimibe (CI-1011)
    • Spring
    • Llaverias G, Laguna JC, Alegret M Pharmacology of the ACAT inhibitor avasimibe (CI-1011). Cardiovasc Drug Rev. 2003 Spring;21(1):33-50.
    • (2003) Cardiovasc Drug Rev , vol.21 , Issue.1 , pp. 33-50
    • Llaverias, G.1    Laguna, J.C.2    Alegret, M.3
  • 23
    • 0028341682 scopus 로고
    • 2-Azetidinones as Inhibitors of Cholesterol Absorption
    • Burnett, D.A.; Caplen, M.A.; Davis, HR. 2-Azetidinones as Inhibitors of Cholesterol Absorption.J. Med. Chem. 1994, 37, 1733-1736.
    • (1994) J Med Chem , vol.37 , pp. 1733-1736
    • Burnett, D.A.1    Caplen, M.A.2    Davis, H.R.3
  • 24
    • 0030848734 scopus 로고    scopus 로고
    • In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461
    • Van Heek M, France CF, Compton DS, et al.In vivo metabolism-based discovery of a potent cholesterol absorption inhibitor, SCH58235, in the rat and rhesus monkey through the identification of the active metabolites of SCH48461. J Pharmacol Exp Ther 1997; 283: 157-63
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 157-163
    • Van Heek, M.1    France, C.F.2    Compton, D.S.3
  • 25
    • 0034003105 scopus 로고    scopus 로고
    • Comparision of the activity and disposition of the novel cholesterol absortion inhibitor, SCH58235, and its glucoronide, SCH60663
    • Van Heek M, Farley C, Compton DS, et al. Comparision of the activity and disposition of the novel cholesterol absortion inhibitor, SCH58235, and its glucoronide, SCH60663. Br J Pharmacol 2000; 129:1748-54
    • (2000) Br J Pharmacol , vol.129 , pp. 1748-1754
    • Van Heek, M.1    Farley, C.2    Compton, D.S.3
  • 26
    • 0011363793 scopus 로고    scopus 로고
    • Effect of food on oral bioavailability of SCH 58235 in healthy male volunteers
    • AAPS Annual Meeting. San Francisco (CA)
    • Punwani N, Pai S, Bach C, et al. Effect of food on oral bioavailability of SCH 58235 in healthy male volunteers. AAPS Annual Meeting.1998; San Francisco (CA), AAPS Annual Meeting Supplement (1): 486
    • (1998) AAPS Annual Meeting Supplement , Issue.1 , pp. 486
    • Punwani, N.1    Pai, S.2    Bach, C.3
  • 27
    • 0000382940 scopus 로고    scopus 로고
    • Effect of age on the pharmacokinetics of ezetimibe
    • American Association of Pharmaceutical Scientists (AAPS)
    • Zhu Y, Statkevich P, Kosoglou T, et al. Effect of age on the pharmacokinetics of ezetimibe. American Association of Pharmaceutical Scientists (AAPS) PharmSci Suppl 2000; 2 (2): 2082
    • (2000) PharmSci Suppl , vol.2 , Issue.2 , pp. 2082
    • Zhu, Y.1    Statkevich, P.2    Kosoglou, T.3
  • 28
    • 18344380806 scopus 로고    scopus 로고
    • Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects
    • Patrick JE, Kosoglou T, Stauber KL, Alton KB, Maxwell SE, Zhu Y, et al. Disposition of the selective cholesterol absorption inhibitor ezetimibe in healthy male subjects. Drug Metab Dispos 2002;30:430-7
    • (2002) Drug Metab Dispos , vol.30 , pp. 430-437
    • Patrick, J.E.1    Kosoglou, T.2    Stauber, K.L.3    Alton, K.B.4    Maxwell, S.E.5    Zhu, Y.6
  • 29
    • 0034985134 scopus 로고    scopus 로고
    • A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe
    • Ezzet F, Krishna G, Wexler DB, et al. A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe. Clin Ther 2001; 23 (6): 871-85
    • (2001) Clin Ther , vol.23 , Issue.6 , pp. 871-885
    • Ezzet, F.1    Krishna, G.2    Wexler, D.B.3
  • 30
    • 0002227224 scopus 로고    scopus 로고
    • Pharmacokinetics of ezetimibe in subjects with normal renal function or severe chronic renal insufficiency
    • Reyderman L, Kosoglou T, Statkevich P, et al. Pharmacokinetics of ezetimibe in subjects with normal renal function or severe chronic renal insufficiency . Clin Pharmacol Ther 2002 ; 71: P27
    • (2002) Clin Pharmacol Ther , vol.71
    • Reyderman, L.1    Kosoglou, T.2    Statkevich, P.3
  • 31
    • 0001584541 scopus 로고    scopus 로고
    • Effect of SCH 58235 on the activity of drug metabolizing enzymes in vivo
    • Zhu Y, Statkevich P, Kosoglou T, et al. Effect of SCH 58235 on the activity of drug metabolizing enzymes in vivo. Clin Pharmacol Ther 2000; 67: 152
    • (2000) Clin Pharmacol Ther , vol.67 , pp. 152
    • Zhu, Y.1    Statkevich, P.2    Kosoglou, T.3
  • 32
    • 0034776367 scopus 로고    scopus 로고
    • Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function
    • Van Heek M, Farley C, Compton DS, et al. Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function. Br J Pharmacol 2001; 134 (2): 409-17
    • (2001) Br J Pharmacol , vol.134 , Issue.2 , pp. 409-417
    • Van Heek, M.1    Farley, C.2    Compton, D.S.3
  • 33
    • 0002075919 scopus 로고    scopus 로고
    • Ezetimibe does not affect the pharmacokinetics of oral contraceptives
    • Keung ACF, Kosoglou T, Statkevich P, et al. Ezetimibe does not affect the pharmacokinetics of oral contraceptives. Clin Pharmacol Ther 2001; 69: P55
    • (2001) Clin Pharmacol Ther , vol.69
    • Keung, A.C.F.1    Kosoglou, T.2    Statkevich, P.3
  • 34
    • 0002075921 scopus 로고    scopus 로고
    • Ezetimibe does not affect the pharmacokinetics or pharmacodynamics of warfarin
    • Bauer KS, Kosoglou T, Statkevich P, et al. Ezetimibe does not affect the pharmacokinetics or pharmacodynamics of warfarin. Clin Pharmacol Ther 2001; 69: P5
    • (2001) Clin Pharmacol Ther , vol.69
    • Bauer, K.S.1    Kosoglou, T.2    Statkevich, P.3
  • 35
    • 0002075922 scopus 로고    scopus 로고
    • Ezetimibe does not affect the pharmacokinetics and pharmacodynamics of glipizide
    • Statkevich P, Reyderman L, Kosoglou T, et al. Ezetimibe does not affect the pharmacokinetics and pharmacodynamics of glipizide. Clin Pharmacol Ther 2001; 69: P67
    • (2001) Clin Pharmacol Ther , vol.69
    • Statkevich, P.1    Reyderman, L.2    Kosoglou, T.3
  • 36
    • 0037111924 scopus 로고    scopus 로고
    • Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia
    • Dujovne CA, Ettinger MP, McNeer JF, et al. Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia. Am J Cardiol 2002; 90:1092-1097
    • (2002) Am J Cardiol , vol.90 , pp. 1092-1097
    • Dujovne, C.A.1    Ettinger, M.P.2    McNeer, J.F.3
  • 37
    • 17944380533 scopus 로고    scopus 로고
    • Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: Pooled analysis of two phase II studies
    • Bays HE, Moore PB, Drehobl MA, et al. Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies. Clin Ther 2001; 23 (8): 1209-30
    • (2001) Clin Ther , vol.23 , Issue.8 , pp. 1209-1230
    • Bays, H.E.1    Moore, P.B.2    Drehobl, M.A.3
  • 38
    • 0000801934 scopus 로고    scopus 로고
    • Results of phase I/II clinical trials with ezetimibe, a novel selective cholesterol absorption inhibitor
    • Stein E. Results of phase I/II clinical trials with ezetimibe, a novel selective cholesterol absorption inhibitor. Eur Heart J Suppl 2001; 3 Suppl. E: E11-6
    • (2001) Eur Heart J Suppl , vol.3 , Issue.SUPPL. E
    • Stein, E.1
  • 39
    • 1442299757 scopus 로고    scopus 로고
    • Effectiveness of Ezetimibe in Clinical Practice
    • Jurado J, MD, Richard Seip, PhD, and Paul D. Thompson, MD. Effectiveness of Ezetimibe in Clinical Practice. Am J Cardiol 2004;93:641-643
    • (2004) Am J Cardiol , vol.93 , pp. 641-643
    • Jurado, J.1    Seip, R.2    Thompson, P.D.3
  • 40
    • 0037395141 scopus 로고    scopus 로고
    • Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia
    • Knopp RH, Gitter H, Truitt T, et al. Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia. Eur Heart J 2003; 24:729-741
    • (2003) Eur Heart J , vol.24 , pp. 729-741
    • Knopp, R.H.1    Gitter, H.2    Truitt, T.3
  • 41
    • 1542722231 scopus 로고    scopus 로고
    • Initial Low-Density Lipoprotein Response to Statin Therapy Predicts Subsequent Low-Density Lipoprotein Response to the Addition of Ezetimibe
    • .Ziajka PE, Reis M, Kreul S, King H. Initial Low-Density Lipoprotein Response to Statin Therapy Predicts Subsequent Low-Density Lipoprotein Response to the Addition of Ezetimibe. Am J Cardiol 2004;93:779-780
    • (2004) Am J Cardiol , vol.93 , pp. 779-780
    • Ziajka, P.E.1    Reis, M.2    Kreul, S.3    King, H.4
  • 42
    • 0035034225 scopus 로고    scopus 로고
    • Determinants of variable response to statin treatment in patients with refractory familial hypercholesterolemia
    • O'Neill F, Patel D, Knight B, et al. Determinants of variable response to statin treatment in patients with refractory familial hypercholesterolemia. Arterioscler ThrombVasc Biol 2001;21:832-837
    • (2001) Arterioscler ThrombVasc Biol , vol.21 , pp. 832-837
    • O'Neill, F.1    Patel, D.2    Knight, B.3
  • 43
    • 0344490262 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: A prospective, randomized, double-blind trial
    • Melani L, Mills R, Hassman D, et al. Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: A prospective, randomized, double-blind trial. Eur Heart J 2003; 24:717-728.
    • (2003) Eur Heart J , vol.24 , pp. 717-728
    • Melani, L.1    Mills, R.2    Hassman, D.3
  • 44
    • 0037441702 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe coadministered with lovastatin in patients with primary hypercholesterolemia
    • Kerzner B, Corbelli J, Sharp S, et al. Efficacy and safety of ezetimibe coadministered with lovastatin in patients with primary hypercholesterolemia. Am J Cardiol 2003; 91:418-424.
    • (2003) Am J Cardiol , vol.91 , pp. 418-424
    • Kerzner, B.1    Corbelli, J.2    Sharp, S.3
  • 45
    • 0037504445 scopus 로고    scopus 로고
    • Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia
    • Ballantyne CM, Houri J, Notarbartolo A, et al. Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia. Circulation 2003; 107:2409-2415
    • (2003) Circulation , vol.107 , pp. 2409-2415
    • Ballantyne, C.M.1    Houri, J.2    Notarbartolo, A.3
  • 46
    • 0037132598 scopus 로고    scopus 로고
    • Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia
    • Davidson MH, McGarry T, Bettis R, et al. Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia. J Am Coll Cardiol 2002; 40:2125-2134.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 2125-2134
    • Davidson, M.H.1    McGarry, T.2    Bettis, R.3
  • 48
    • 5444270779 scopus 로고    scopus 로고
    • Effects of ezetimibe added to on-going statin therapy on the lipid profile of hypercholesterolemic patients with diabetes mellitus or metabolic syndrome
    • Simons L, Melvin Tonkon, Luis Masana, Darbie Maccubbin, Arvind Shah, Michael Lee and Barry Gumbiner. Effects of ezetimibe added to on-going statin therapy on the lipid profile of hypercholesterolemic patients with diabetes mellitus or metabolic syndrome .CUR MED RES OPIN. 2004; 20(9): 1437-1445
    • (2004) Cur Med Res Opin , vol.20 , Issue.9 , pp. 1437-1445
    • Simons, L.1    Tonkon, M.2    Masana, L.3    Maccubbin, D.4    Shah, A.5    Lee, M.6    Gumbiner, B.7
  • 49
    • 0035572836 scopus 로고    scopus 로고
    • Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice
    • Dec
    • Davis HR Jr, Compton DS, Hoos L, Tetzloff G. Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice. Arterioscler Thromb Vasc Biol. 2001 Dec;21(12):2032-8.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , Issue.12 , pp. 2032-2038
    • Davis Jr., H.R.1    Compton, D.S.2    Hoos, L.3    Tetzloff, G.4
  • 50
    • 0033552130 scopus 로고    scopus 로고
    • Colesevelam hydrochloride (cholestagel): A new, potent bile acid sequestrant associated with a low incidence of gastrointestinal side effects
    • Davidson MH, Dillon MA, Gordon B, et al.Colesevelam hydrochloride (cholestagel): a new, potent bile acid sequestrant associated with a low incidence of gastrointestinal side effects. Arch Intern Med 1999;159:1893-900
    • (1999) Arch Intern Med , vol.159 , pp. 1893-1900
    • Davidson, M.H.1    Dillon, M.A.2    Gordon, B.3
  • 51
    • 4544350316 scopus 로고    scopus 로고
    • Effectiveness and Tolerability of Ezetimibe Add-on Therapy to a Bile Acid Resin-Based Regimen for Hypercholesterolemia
    • Xydakis AM, Guyton JR, Chiou P, et al. Effectiveness and Tolerability of Ezetimibe Add-on Therapy to a Bile Acid Resin-Based Regimen for Hypercholesterolemia. Am J Cardiol. 2004;94:795-797.
    • (2004) Am J Cardiol , vol.94 , pp. 795-797
    • Xydakis, A.M.1    Guyton, J.R.2    Chiou, P.3
  • 53
    • 4544247030 scopus 로고    scopus 로고
    • Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil
    • Sep
    • Reyderman L, Kosoglou T, Statkevich P, Pember L, Boutros T, Maxwell SE, Affrime M, Batra .Assessment of a multiple-dose drug interaction between ezetimibe, a novel selective cholesterol absorption inhibitor and gemfibrozil.Int J Clin Pharmacol Ther. 2004 Sep;42(9):512-8.
    • (2004) Int J Clin Pharmacol Ther , vol.42 , Issue.9 , pp. 512-518
    • Reyderman, L.1    Kosoglou, T.2    Statkevich, P.3    Pember, L.4    Boutros, T.5    Maxwell, S.E.6    Affrime, M.7    Batra8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.