Alterations of renal phenotype and gene expression profiles due to protein overload in NOD-related mouse strains

BMC Nephrology

Volumn 6, Issue , 2005, Pages

  Wilson, Karen H S ^a,e   McIndoe, Richard A ^a   Eckenrode, Sarah ^a   Morel, Laurence ^b   Agarwal, Anupam ^d   Croker, Byron P ^b,c   She, Jin Xiong ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e ROYAL SWEDISH ACADEMY OF SCIENCES   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CALMODULIN KINASE BETA; MANNOSIDASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG; BOVINE SERUM ALBUMIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE COURSE; DOWN REGULATION; FEMALE; GENE EXPRESSION PROFILING; HISTOLOGY; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOLECULAR CLONING; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PROTEINURIA; SIGNAL TRANSDUCTION; TISSUE MICROARRAY; ANIMAL; DIABETES MELLITUS; DISEASE PREDISPOSITION; DNA MICROARRAY; GENE EXPRESSION; KIDNEY; METABOLISM; MOUSE; NONOBESE DIABETIC MOUSE; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; DIABETES MELLITUS; DIABETIC NEPHROPATHIES; DISEASE SUSCEPTIBILITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; KIDNEY; MICE; MICE, INBRED NOD; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PROTEINURIA; SERUM ALBUMIN, BOVINE;

EID: 31144451231     PISSN: 14712369     EISSN: 14712369     Source Type: Journal    
DOI: 10.1186/1471-2369-6-17     Document Type: Article

References (50)

1. Excerpts from the United States Renal Data Systems 2002 annual report: Atlas of end-stage renal disease in the United States. American Journal of Kidney Diseases 2003, S7-254:S7-254.
2. Croker BP, Dawson DV, Sanfilippo F: IgA Nephropathy. Correlation of Clinical and Histologic Features. Laboratory Investigation 1983, 48:19-24.
3. Walls J: Relationship between proteinuria and progressive renal disease. American Journal of Kidney Diseases 2001, 37:S13-S16.
4. Wilson KHS, Eckenrode SE, Li QZ, Ruan QG, Yang P, Shi JD, Davoodi-Semiromi A, McIndoe RA, Croker BP, She JX: Microarray analysis of gene expression in the kidneys of new- and post-onset diabetic NOD mice. Diabetes 2003, 52:2151-2159.
5. Chen A, Wei CH, Sheu LF, Ding SL, Lee WH: Induction of Proteinuria by Adriamycin or Bovine Serum-Albumin in the Mouse. Nephron 1995, 69:293-300.
6. Eddy AA, Kim H, Lopez-Guisa J, Oda T, Soloway PD, McCulloch L, Liu E, Wing D: Interstitial fibrosis in mice with overload proteinuria: Deficiency of TIMP-1 is not protective. Kidney International 2000, 58:618-628.
7. Nagasawa Y, Takenaka M, Kaimori J, Matsuoka Y, Akagi Y, Tsujie M, Imai E, Hori M: Rapid and diverse changes of gene expression in the kidneys of protein-overload proteinuria mice detected by microarray analysis. Nephrology Dialysis Transplantation 2001, 16:923-931.
8. Kimmelstiel P, Wilson C: Intercapillary lesions in glomeruli of kidney. American Journal of Pathology 1936, 12:83-97.
9. Burkholder PM: Stalk glomerulonephropathy. In Atlas of human glomerular pathology; correlative light, immunofluorescence, and ultrastructural histology Hagerstown, Harper & Row; 1974.
10. Watanabe Y, Itoh Y, Yoshida F, Koh N, Tamai H, Fukatsu A, Matsuo S, Hotta N, Sakamoto N: Unique Glomerular Lesion with Spontaneous Lipid Deposition in Glomerular Capillary Lumina in the Non Strain of Mice. Nephron 1991, 58:210-218.
11. Koarada S, Wu Y, Yim YS, Wakeland EW, Ridgway WM: Nonobese diabetic CD4 lymphocytosis maps outside the MHC locus on chromosome 17. Immunogenetics 2004, 56:333-337.
12. Mishra R, Emancipator SN, Miller C, Kern T, Simonson MS: Adipose differentiation-related protein and regulators of lipid homeostasis identified by gene expression profiling in the murine db/db diabetic kidney. Am J Physiol Renal Physiol 2004, 286:F913-21.
13. Susztak K, Bottinger E, Novetsky A, Liang D, Zhu Y, Ciccone E, Wu D, Dunn S, McCue P, Sharma K: Molecular profiling of diabetic mouse kidney reveals novel genes linked to glomerular disease. Diabetes 2004, 53:784-794.
14. Anastassiou G, Duensing S, Steinhoff G, Zorn U, Grosse J, Dallmann I, Kirchner H, Ganser A, Atzpodien J: Platelet endothelial cell adhesion molecule-1 (PECAM-1): A potential prognostic marker involved in leukocyte infiltration of renal cell carcinoma. Oncology 1996, 53:127-132.
15. Mishra R, Leahy P, Simonson MS: Gene expression profiling reveals role for EGF-family ligands in mesangial cell proliferation. Am J Physiol Renal Physiol 2002, 283:F1151-9.
16. Coulis CM, Lee C, Nardone V, Prokipcak RD: Inhibition of c-myc expression in cells by targeting an RNA-protein interaction using antisense oligonucleotides. Molecular Pharmacology 2000, 57:485-494.
17. Menne J, Park JK, Boehne M, Elger M, Lindschau C, Kirsch T, Meier M, Gueler F, Fiebeler A, Bahlmann FH, Leitges M, Haller H: Diminished loss of proteoglycans and lack of albuminuria in protein kinase C-alpha-deficient diabetic mice. Diabetes 2004, 53:2101-2109.
18. Flyvbjerg A, Bennett WF, Rasch R, Kopchick JJ, Scarlett JA: Inhibitory effect of a growth hormone receptor antagonist (G120K-PEG) on renal enlargement, glomerular hypertrophy, and urinary albumin excretion in experimental diabetes in mice. Diabetes 1999, 48:377-382.
19. Nakajima H, Takenaka M, Kaimori JY, Hamano T, Iwatani H, Sugaya T, Ito T, Hori M, Imai E: Activation of the signal transducer and activator of transcription signaling pathway in renal proximal tubular cells by albumin. J Am Soc Nephrol 2004, 15:276-285.
20. McDuffie M: Derivation of diabetes-resistant congenic lines from the nonobese diabetic mouse. Clin Immunol 2000, 96:119-130.
21. Schwartz F, Duka A, Triantafyllidi E, Johns C, Duka I, Cui J, Gavras H: Serial analysis of gene expression in mouse kidney following angiotensin II administration. Physiol Genomics 2003, 16:90-98.
22. Wyles JP, McMaster CR, Ridgway ND: Vesicle-associated membrane protein-associated protein-A (VAP-A) interacts with the oxysterol-binding protein to modify export from the endoplasmic reticulum. Journal of Biological Chemistry 2002, 277:29908-29918.
23. Thongboonkerd V, Barati MT, McLeish KR, Benarafa C, Remold-O'Donnell E, Zheng S, Rovin BH, Pierce WM, Epstein PN, Klein JB: Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis. J Am Soc Nephrol 2004, 15:650-662.
24. Zheng S, Noonan WT, Metreveli NS, Coventry S, Kralik PM, Carlson EC, Epstein PN: Development of late-stage diabetic nephropathy in OVE26 diabetic mice. Diabetes 2004, 53:3248-3257.
25. Kim EH, Lee CH, Hyun BH, Suh JG, Oh YS, Namikawa T, Ishikawa A: Quantitative trait loci for proteinuria in the focal glomerulosclerosis mouse model. Mamm Genome 2005, 16:242-250.
26. Serreze DV, Leiter EH: Genetic and Pathogenic Basis of Autoimmune Diabetes in Nod Mice. Current Opinion in Immunology 1994, 6:900-906.
27. Wicker LS, Todd JA, Peterson LB: Genetic-Control of Autoimmune Diabetes in the Nod Mouse. Annual Review of Immunology 1995, 13:179-200.
28. Bower G, Brown DM, Steffes MW, Vernier RL, Mauer SM: Studies of the glomerular mesangium and the juxtaglomerular apparatus in the genetically diabetic mouse. Laboratory Investigation 1980, 43:333-341.
29. Bak M, Thomsen K, Christiansen T, Flyvbjerg A: Renal enlargement precedes renal hyperfiltration in early experimental diabetes in rats. Journal of the American Society of Nephrology 2000, 11:1287-1292.
30. Hebert LA, Agarwal G, Sedmak DD, Mahan JD, Becker W, Nagaraja HN: Proximal tubular epithelial hyperplasia in patients with chronic glomerular proteinuria. Kidney International 2000, 57:1962-1967.
31. Wesson LG: Compensatory Growth and Other Growth-Responses of the Kidney. Nephron 1989, 51:149-184.
32. Marcussen N, Nyengaard JR, Christensen S: Compensatory Growth of Glomeruli Is Accomplished by an Increased Number of Glomerular Capillaries. Laboratory Investigation 1994, 70:868-874.
33. Nataraj C, Oliverio MI, Mannon RB, Mannon PJ, Audoly LP, Amuchastegui CS, Ruiz P, Smithies O, Coffman TM: Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway. Journal of Clinical Investigation 1999, 104:1693-1701.
34. Hughes K, Edin S, Antonsson A, Grundstrom T: Calmodulin-dependent kinase II mediates T cell receptor/CD3-and phorbol ester-induced activation of I kappa B kinase. Journal of Biological Chemistry 2001, 276:36008-36013.
35. Baelde HJ, Eikmans M, Doran PP, Lappin DW, de Heer E, Bruijn JA: Gene expression profiling in glomeruli from human kidneys with diabetic nephropathy. Am J Kidney Dis 2004, 43:636-650.
36. Botella LM, Puig-Kroger A, Almendro N, Sanchez-Elsner T, Munoz E, Corbi A, Bernabeu C: Identification of a functional NF-kappa B site in the platelet endothelial cell adhesion molecule-1 promoter. Journal of Immunology 2000, 164:1372-1378.
37. Tumlin JA, Lea JP, Swanson CE, Smith CL, Edge SS, Someren JS: Aldosterone and dexamethasone stimulate calcineurin activity through a transcription- independent mechanism involving steroid receptor-associated heat shock proteins. Journal of Clinical Investigation 1997, 99:1217-1223.
38. Lebihan S, Renoir JM, Radanyi C, Chambraud B, Joulin V, Catelli MG, Baulieu EE: The Mammalian Heat-Shock Protein-Binding Immunophilin (P59/Hbi) Is an Atp and Gtp-Binding Protein. Biochemical and Biophysical Research Communications 1993, 195:600-607.
39. Yamamoto-Yamaguchi Y, Okabe-Kado J, Kasukabe T, Honma Y: Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors. Experimental Hematology 2001, 29:582-588.
40. Chambraud B, Radanyi C, Camonis JH, Rajkowski K, Schumacher M, Baulieu EE: Immunophilins, Refsum disease, and lupus nephritis: The peroxisomal enzyme phytanoyl-COA alpha-hydroxylase is a new FKBP-associated protein. Proceedings of the National Academy of Sciences of the United States of America 1999, 96:2104-2109.
41. Li J, Takaishi K, Cook W, McCorkle SK, Unger RH: Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes. Proceedings of the National Academy of Sciences of the United States of America 2003, 100:9476-9481.
42. Yamashita H, Nagai Y, Takamura T, Nohara E, Kobayashi K: Thiazolidinedione derivatives ameliorate albuminuria in streptozotocin-induced diabetic spontaneous hypertensive rat. Metabolism 2002, 51:403-408.
43. Isshiki K, Haneda M, Koya D, Maeda S, Sugimoto T, Kikkawa R: Thiazolidinedione compounds ameliorate glomerular dysfunction independent of their insulin-sensitizing action in diabetic rats. Diabetes 2000, 49:1022-1032.
44. Yotsumoto T, Naitoh T, Kanaki T, Matsuda M, Tsuruzoe N: A novel peroxisome proliferator-activated receptor (PPAR)gamma agonist, NIP-222, reduces urinary albumin excretion in streptozotocin-diabetic mice independent of PPARgamma activation. Metabolism 2003, 52:1633-1637.
45. Baylis C, Atzpodien EA, Freshour G, Engels K: Peroxisome proliferator-activated receptor [gamma] agonist provides superior renal protection versus angiotensin-converting enzyme inhibition in a rat model of type 2 diabetes with obesity. J Pharmacol Exp Ther 2003, 307:854-860.
46. Ma LJ, Marcantoni C, Linton MF, Fazio S, Fogo AB: Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats. Kidney Int 2001, 59:1899-1910.
47. Shipley JM, Waxman DJ: Down-regulation of STAT5b transcriptional activity by ligand-activated peroxisome proliferator-activated receptor (PPAR) alpha and PPAR gamma. Molecular Pharmacology 2003, 64:355-364.
48. Cella N, Groner B, Hynes NE: Characterization of Stat5a and Stat5b homodimers and heterodimers and their association with the glucocortiocoid receptor in mammary cells. Molecular and Cellular Biology 1998, 18:1783-1792.
49. Martins TC, Aguas AP: Involvement of c-myc in the resistance of non-obese diabetic mice to glucocorticoid-induced apoptosis. Immunology 1998, 95:377-382.
50. Davoodi-Semiromi A, Laloraya M, Kumar GP, Purohit S, Jha RK, She JX: A mutant stat5b with weaker DNA binding affinity defines a key defective pathway in nonobese diabetic mice. Journal of Biological Chemistry 2004, 279:11553-11561.