Quantitative trait loci for proteinuria in the focal glomerulosclerosis mouse model

Mammalian Genome

Volumn 16, Issue 4, 2005, Pages 242-250

  Kim, Eun Hee ^a   Lee, Chul Ho ^b   Hyun, Byung Hwa ^b   Suh, Jun Gyo ^c   Oh, Yang Seok ^c   Namikawa, Takao ^a   Ishikawa, Akira ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Hallym University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACKCROSSING; CHROMOSOME; CONTROLLED STUDY; FEMALE; FOCAL GLOMERULOSCLEROSIS; GENE LOCATION; GENETIC REGULATION; GENOME ANALYSIS; MALE; MOLECULAR INTERACTION; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PROGENY; PROTEINURIA; QUANTITATIVE TRAIT LOCUS; STANDARD;

ANALYSIS OF VARIANCE; ANIMALS; CHROMOSOME MAPPING; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; ELECTROPHORESIS, AGAR GEL; EPISTASIS, GENETIC; GENOTYPE; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; MICE; MICE, MUTANT STRAINS; PROTEINURIA; QUANTITATIVE TRAIT LOCI;

ANIMALIA;

EID: 21244460007     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-004-3023-7     Document Type: Article

References (37)

1. B Antus P Hamar G Kokeny Z Szollosi I Mucsi 2003 Estradiol is nephroprotective in the rat remnant kidney Nephrol Dial Transplant 18 54 61
2. N Boute O Gribouval S Roselli F Benessy H Lee 2000 NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome Nat Genet 24 349 354
3. DM Brown AP Provoost MJ Daly ES Lander HJ Jacob 1996 Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat Nat Genet 12 44 51
4. GA Churchill RW Doerge 1996 Empirical threshold values for quantitative trait mapping Genetics 138 963 971
5. P Devarajan A Spitzer 2002 Towards a biological characterization of focal segmental glomerulosclerosis Am J Kidney Dis 39 625 636
6. MR Garrett H Dene JP Rapp 2003 Time-course genetic analysis of albuminuria in Dahl salt-sensitive rats on low-salt diet J Am Soc Nephrol 14 1175 1187
7. CS Haley SA Knott 1992 A simple regression method for mapping quantitative trait loci in line crosses using flanking markers Heredity 69 315 324
8. RC Harris 1999 Molecular basis of injury and progression in focal gloemerulosclerosis Nephron 82 289 299
9. BH Hyun N Wakasugi M Nose T Saito T Tomita 1991 A new mouse strain manifesting high proteinuria and kidney glomerular defect Lab Anim Sci 41 442 446
10. A Ishikawa T Namikawa 2004 Mapping major quantitative trait loci for postnatal growth in an intersubspecific backcross between C57BL/6J and Philippine wild mice by using principal component analysis Genes Genet Syst 79 27 39
11. DH Kang ES Yu KI Yoon R Johnson 2004 The impact of gender on progression of renal disease: potential role of estrogen-mediated vascular endothelial growth factor regulation and vascular protection Am J Pathol 164 679 688
12. CH Kao ZB Zeng RD Teasdale 1999 Multiple interval mapping for quantitative trait loci Genetics 152 1203 1216
13. JM Kaplan SH Kim KN North H Rennke LA Correia 2000 Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis Nat Genet 24 251 256
14. M Kestila U Lenkkeri M Mannikko J Lamerdin P McCready 1998 Positionally cloned gene for a novel glomerular protein-nephrin-is mutated in congenital nephritic syndrome Mol Cell 1 575 582
15. EH Kim KS Choi KW Lee JG Suh YK Choi 2004 Changes of renal lesion-related parameters in FGS/Nga and the parental mouse strains, CBA/N and RFM/Nga Exp Anim 53 97 102
16. JM Kim H Wu G Green CA Winkler JB Kopp 2003 CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility Science 300 1298 1300
17. SA Knott L Marklund CS Haley K Andersson W Davies 1998 Multiple marker mapping of quantitative trait loci in a cross between outbred wild boar and large white pigs Genetics 149 1069 1080
18. R Korstanje K DiPetrillo 2004 Unraveling the genetics of chronic kidney disease using animal models Am J Physiol Renal Physiol 287 F347 F352
19. ES Lander D Botstein 1989 Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps Genetics 121 185 199
20. JH Lipschutz 1998 Molecular development of the kidney: a review of the results of gene disruption studies Am J Kidney Dis 31 383 397
21. KF Manly RH Jr Cudmore JM Meer 2001 Map Manager QTX, cross-platform software for genetic mapping Mamm Genome 12 930 932
22. BJ Mathis SH Kim K Calabrese M Haas JG Seidman 1998 A locus for inherited focal segmental glomerulosclerosis maps to chromosome 19q13 Kidney Int 53 282 286
23. S Murayama S Yagyu K Higo C Ye T Mizuno 1998 A genetic locus susceptible to the overt proteinuria in BUF/Mna rat Mamm Genome 9 886 888
24. T Ostendorf U Kunter HJ Grone F Bahlmann H Kawachi 2001 Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis J Am Soc Nephrol 12 909 918
25. R Quintanilla D Milan JP Bidanel 2002 A further look at quantitative trait loci affecting growth and fatness in a cross between Meishan and Large White pig populations Genet Sel Evol 34 193 210
26. JP Rapp 2000 Genetic analysis of inherited hypertension in the rat Physiol Rev 80 135 172
27. A Remuzzi S Puntorieri M Alfano D Macconi M Abbate 1992 Pathophysiologic implications of proteinuria in a rat model of progressive glomerular injury Lab Invest 67 572 579
28. A Schulz A Litfin P Kossmehl R Kreutz 2002 Genetic dissection of increased urinary albumin excretion in the munich wistar fromter rat J Am Soc Nephrol 13 2706 2714
29. G Seaton CS Haley SA Knott M Kearsey PM Visscher 2002 QTL Express: Mapping quantitative trait loci in simple and complex pedigrees Bioinformatics 18 339 340
30. S Sen GA Churchill 2001 A statistical framework for quantitative trait mapping Genetics 159 371 387
31. M Sharma R Sharma ET McCarthy VJ Savin 1999 "The FSGS factor." enrichment and in vivo effect of activity from focal segmental glomerulosclerosis plasma J Am Soc Nephrol 10 552 561
32. M Shiozawa AP Provoost RP van Dokkum RR Majewski HJ Jacob 2000 Evidence of gene-gene interactions in the genetic susceptibility to renal impairment after unilateral nephrectomy J Am Soc Nephrol 11 2068 2078
33. P Upadhya EH Birkenmeier CS Birkenmeier JE Barker 2000 Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice Proc Natl Acad Sci USA 97 217 221
34. S Wang CJ Basten ZB Zeng 2004 Windows QTL Cartographer 2.0 Department of Statistics, North Carolina State University Raleigh, NC
35. MP Winn PJ Conlon KL Lyun DN Howell DA Gross 1999 Clinical and genetic heterogeneity in familial focal segmental glomerulosclerosis Kidney Int 55 1241 1246
36. F Yoshida S Matsuo H Fujishima HY Kim T Tomita 1994 Renal lesions of the FGS strain of mice: a spontaneous animal model of progressive glomerulosclerosis Nephron 66 317 325
37. ZB Zeng 1993 Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci Proc Natl Acad Sci USA 90 10972 10976