Characterization of the lipolytic pathways that mediate free fatty acid release during Fas/CD95-induced apoptosis

Apoptosis

Volumn 10, Issue 6, 2005, Pages 1369-1381

  Iturralde, M ^a   Pardo, J ^a   Lacasa, E ^a   Barrio, G ^a   Alava, M A ^a   Pineiro A ^a   Naval, J ^a   Anel, A ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Apoptosis; Arachidonate; Fas CD95; Palmitate

Indexed keywords

1,6 HEXAMETHYLENEDICARBAMIC ACID BIS(CYCLOHEXANONE OXIME) ESTER; 2 ARACHIDONOYLGLYCEROL; ARACHIDONIC ACID; BROMOENOL LACTONE; ENDOCANNABINOID; FAS ANTIGEN; FATTY ACID; LIPOPROTEIN LIPASE; PALMITIC ACID; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPASE C INHIBITOR; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE;

ACID SECRETION; APOPTOSIS; ARTICLE; CELL CULTURE; ENZYME ACTIVITY; FATTY ACID ANALYSIS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIPID ANALYSIS; LIPOLYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SUPERNATANT;

ANTIGENS, CD95; APOPTOSIS; ARACHIDONIC ACIDS; BRIDGED COMPOUNDS; CYCLOHEXANONES; ENZYME INHIBITORS; FATTY ACIDS, NONESTERIFIED; GLYCERIDES; HUMANS; JURKAT CELLS; KETONES; LIPID METABOLISM; LIPOLYSIS; LIPOPROTEIN LIPASE; MODELS, BIOLOGICAL; PALMITIC ACID; PHOSPHATIDIC ACIDS; PHOSPHATIDYLCHOLINES; THIONES; TYPE C PHOSPHOLIPASES;

EID: 30944468349     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-005-1511-1     Document Type: Article

References (50)

1. 2 activation in tumour cell killing by tumour necrosis factor. Immunology 1988; 64: 81-85.
2. 2, which undergoes protolytic inactivation. J Biol Chem 1998; 273: 13870-13877.
3. 2 is not involved in Fas-mediated apoptosis. Eur J Biochem 1996; 236: 533-538.
4. Koren HS, Ferber E, Fischer H. Changes in phospholipid metabolism of a tumor target cell during a cell-mediated cytotoxic reaction. Biochim Biophys Acta 1971; 231: 520-526.
5. Richieri GV, Kleinfeld AM. Free fatty acids are produced in and secreted from target cells very early in cytotoxic T lymphocyte-mediated killing. J Immunol 1991; 147: 2809-2815.
6. Brekke OL, Sagen E, Bjerve KS. Specificity of endogenous fatty acid release during TNF-induced apoptosis in WEHI 164 fibrosarcoma cells. J Lipid Res 1999; 40: 2223-2233.
7. Iturralde M, Gamen S, Pardo, et al. Saturated free fatty acids release and intracellular ceramide generation during apoptosis induction are closely related processes. Biochim Biophys Acta 2003; 1634: 40-51.
8. Nagata S. Apoptosis by death factor. Cell 1997; 88: 355-365.
9. Nicholson DW, Thornberry NA. Caspases : Killer proteases. Trends Biochem Sci 1997; 22: 299-306.
10. Cifone MG, De Maria R, Roncaioli, et al. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J Exp Med 1993; 177: 1547-1552.
11. Gamen S, Marzo I, Anel A, Piñeiro A, Naval J. CPP32 inhibition prevents Fas-induced ceramide generation and apoptosis in human cells. FEBS Lett 1996; 390: 233-237.
12. Tepper AD, Boesen-de Cock JGR, de Vries E, Borst J, van Blitterswijk WJ. CD95/Fas-induced ceramide formation proceeds with slow kinetics and is not blocked by caspase-3/CPP32 inhibition. J Biol Chem 1997; 272: 24308-24312.
13. Tepper AD, de Vries E, van Blitterswijk WJ, Borst J. Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis. J. Clin Invest 1999; 103: 971-978.
14. Tepper AD, Ruurs P, Wiedmer T, Sims PJ, Borst J, van Blitterswijk WJ. Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology. J Cell Biol 2000; 150: 155-164.
15. Savill J, Fadok V. Corpse clearance defines the meaning of cell death. Nature 2000; 407: 784-788.
16. 2. Nature Immunol 2003; 4: 387-393.
17. 2 during apoptosis. J Immunol 1998; 161: 5687-5694.
18. 2 in fatty acid release in the cell death pathway. J Biol Chem 2000; 275: 18248-18258.
19. Lauber K, Bohn E, Kröber, et al. Apoptotic cells induce migration of phagocytic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell 2003; 113: 717-730.
20. Müller-Decker K. Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound : Inhibition of a phospholipase C-type reaction. Biochem Biophys Res Commun 1989; 162: 198-205.
21. Schütze S, Potthoff K, Machleidt T, Berkovic D, Wiegmann K, Krönke M. TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 1992; 71: 765-776.
22. Stella N, Schweitzer P, Piomelli D. A second endogenous cannabinoid that modulates long-term potentiation. Nature 1997; 388: 773-778.
23. 2 and diglyceride lipase. Selective inhibition of diglyceride lipase by RHC 80267. J Biol Chem 1982; 257: 14006-14010.
24. 2 by bromoenol lactone and trifluoromethyl ketones. J Biol Chem 1995; 270: 445-450.
25. Di Marzo V, Bisogno T, De Petrocellis, et al. Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages. Eur J Biochem 1999; 264: 258-267.
26. Cabanillas JA, Pacheco-Castro A, Zapata, et al. T cell transformation with Herpesvirus saimiri : A tool for primary immunodeficiencies research. Recent Res Devel Immunology 2002; 4: 382-394.
27. Alley MC, Scudiero DA, Monks, et al. Sensibility of drug screening with panels of human tumor cell lines using microculture tetrazolium assay. Cancer Res 1988; 46: 589-601.
28. Anel A, Buferne M, Boyer C, Schmitt-Verhulst AM, Golstein P. T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin. A Eur J Immunol 1994; 24: 2469-2476.
29. Pardo J, Balkow S, Anel A, Simon MM. The differential contribution of granzyme A and granzyme B in CTL-mediated apoptosis is determined by the quality of target cells. Eur J Immunol 2002; 32: 1980-1985.
30. Anel A, Naval J, Desportes P, Gonzalez B, Uriel J, Piñeiro A. Increased cytotoxicity of polyunsaturated fatty acids on human tumoral B and T-cell lines compared with normal lymphocytes. Leukemia 1992; 6: 680-688.
31. Jacobsson SO, Wallin T, Fowler CJ. Inhibition of Rat C6 Glioma Cell Proliferation by Endogenous and Synthetic Cannabinoids. Relative Involvement of Cannabinoid and Vanilloid Receptors. J Pharmacol Exp Ther 2001; 299: 951-959.
32. Anel A, Naval J, González, et al. Fatty acid metabolism in human lymphocytes. I. Time-course changes in fatty acid composition and membrane fluidity during blastic transformation of peripheral blood lymphocytes. Biochim Biophys Acta 1990; 1044: 323-331.
33. Zhang J, Driscoll TA, Hannun YA, Obeid LM. Regulation of membrane release in apoptosis. Biochem J 1998; 334: 479-485.
34. Anel A, Gamen S, Alava MA, Schmitt-Verhulst AM, Piñeiro A, Naval J. Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones. J Immunol 1997; 158: 1999-2006.
35. Bisogno T, Sepe N, Melck D, Maurelli S, De Petrocellis L, Di Marzo V. Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells. Biochem J 1997; 322: 671-677.
36. Di Marzo V, De Petrocellis L, Sugiura T, Waku K. Potential Biosynthetic Connections between the Two Cannabimimetic Eicosanoids, Anandamide and 2-Arachidonoyl-Glycerol, in Mouse Neuroblastoma Cells. Biochem Biophys Res Commun 1996; 227: 281-288.
37. Bisogno T, Maccarrone M, De Petrocellis, et al. The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors. Eur J Biochem 2001; 268: 1982-1989.
38. 2+ entry. J Biol Chem 2003; 278: 11909-11915.
39. Paumen MB, Ishida Y, Muramatsu M, Yamamoto M, Honjo T. Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis. J Biol Chem 1997; 272: 3324-3329.
40. Richieri GV, Anel A, Kleinfeld AM. Interactions of long-chain fatty acids and albumin: Determination of free fatty acid levels using the fluorescent probe ADIFAB. Biochemistry 1993; 32: 7574-7580.
41. Chow SC, Sisfontes L, Björkhem I, Jondal M. Supression of growth in a leukemic T cell line by n-3 and n-6 polyunsaturated fatty acids. Lipids 1989; 24: 700-704.
42. Luberto C, Hannun Y. Sphingomyelin Synthase, a Potential Regulator of Intracellular Levels of Ceramide and Diacylglycerol during SV40 Transformation. Does Sphingomyelin synthase account for the putative PC-specific PLC? J Biol Chem 1998; 273: 14550-14559.
43. Bratton DL, Fadok VA, Richter, et al. Polyamine regulation of plasma membrane phospholipid flip-flop during apoptosis. J Biol Chem 1999; 274: 28113-28120.
44. Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RA, Henson PM. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 2000; 405: 85-90.
45. Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 1992; 148: 2207-2216.
46. Bisogno T, Howell F, Williams, et al. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J Cell Biol 2003; 163: 463-468.
47. Balsinde J, Diez E, Mollinedo F. Arachidonic acid release from diacylglycerol in human neutrophils. Translocation of diacylglycerol-deacylating enzyme activities from an intracellular pool to plasma membrane upon cell activation. J Biol Chem 1991; 266: 15638-15643.
48. Ramoni C, Spadaro F, Barletta B, Dupuis ML, Podo F. Phosphatidylcholine- specific phospholipase C in mitogen-stimulated fibroblasts. Exp Cell Res 2004; 299: 370-382.
49. Pandol SJ, Hsu YL, Kondratenko NF, Schoffield-Payne MS, Steinbach JH. Dual pathways for agonist-stimulated arachidonic acid release in pancreatic acini: Roles in secretion. Am J Physiol 1991; 260: G423-G433.
50. Hou W, Arita Y, Morisset J. Caerulein-stimulated arachidonic acid release in rat pancreatic acini: A diacylglycerol lipase affair. Am J Physiol 1996; 271: C1735-C1742.