The significance of anemia in squamous cell head and neck cancer treated with surgery and postoperative radiotherapy

Oral Oncology

Volumn 42, Issue 2, 2006, Pages 131-138

  Van De Pol, Sandrine M G ^a   Doornaert, Patricia A H ^a   De Bree, Remco ^a   Leemans, C René ^a   Slotman, Ben J ^a   Langendijk, Johannes A ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Anemia; Head and neck cancer; Hemoglobin; Postoperative radiotherapy; Prognostic factors

Indexed keywords

HEMOGLOBIN;

ADULT; ADVANCED CANCER; AGED; ANEMIA; ARTICLE; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HEAD AND NECK CANCER; HUMAN; MAJOR CLINICAL STUDY; MALE; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROGNOSIS; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; ANEMIA; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; EPIDEMIOLOGIC METHODS; FEMALE; HEAD AND NECK NEOPLASMS; HEMOGLOBINS; HUMANS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POSTOPERATIVE PERIOD; PROGNOSIS; RADIOTHERAPY, ADJUVANT; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 30844469074     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2005.06.021     Document Type: Article

References (23)

1. P. Kumar Impact of anemia in patients with head and neck cancer Oncologist 5 suppl 2 2000 13 18
2. M.J. van Acht, J. Hermans, D.E. Boks, and J.W.H. Leer The prognostic value of hemoglobin and a decrease hemoglobin during radiotherapy in laryngeal carcinoma Int J Radiat Oncol Biol Phys 23 1992 229 235
3. W.R. Lee, B. Berkey, and V. Marial Anemia is associated with decreased survival and increased locoregional failure in patients with locally advanced head and neck carcinoma: a secondary analysis of RTOG 85-27 Int J Radiat Oncol Biol Phys 42 1998 1069 1075
4. L.E. Smeele, J. Irish, P.J. Gullane, P. Neligan, D.H. Brown, and L.E. Rotstein A retrospective comparison of the morbidity and cost of different reconstructive strategies in oral and oropharyngeal carcinoma Laryngoscope 109 1999 800 804
5. S.N. Scott, T.J. Boeve, and T.M. McCulloch The effects of epoetin alfa on transfusion requirements in head and neck cancer patients: a prospective randomised, placebo-controlled study Laryngoscope 112 2002 1221 1229
6. A. Becker, and P. Stadler Severe anemia is associated with poor tumor oxygenation in head and neck squamous cell carcinomas Int J Radiat Oncol Biol Phys 46 2000 459 466
7. L.H. Gray, and A.D. Conger The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy Br J Radiol 26 1953 638 648
8. P. Vaupel, D. Kelleher, and M. Höckel Oxygenation status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy Sem in Oncol 28 2 suppl 8 2001 29 35
9. L.H. Sobin, and Ch. Wittekind Head and neck tumours TNM classification of malignant tumours 1997 John Wiley and Sons New York 17 50
10. L.J. Peters, H. Goepfert, and K.K. Ang Evaluation of the dose for postoperative radiation therapy of head and neck cancer: first report of a prospective randomised trial Int J Radiat Oncol Biol Phys 30 1993 181 182
11. J.A. Langendijk, M.A. de Jong, and C.R. Leemans Postoperative radiotherapy in squamous cell carcinoma of the oral cavity: the importance of the overall treatment time Int J Radiat Oncol Biol Phys 57 2003 693 700
12. O. Reichel, M. Panzer, C. Wimmer, E. Dühmke, E. Kastenbauer, and M. Suckfüll Prognostic implications of hemoglobin levels before and after surgery as well as before and after radiochemotherapy for head and neck tumors Eur Arch Otorhinolaryngol 260 2003 248 253
13. P.F. Nguyen-Tan, Q.T. Le, J.M. Quivey, and M. Singer Treatment results and prognostic factors of advanced T3-4 laryngeal carcinoma: the university of California, San Francisco (UCSF) and Stanford university hospital (SUH) experience Int J Radiat Oncol Biol Phys 50 2001 1172 1180
14. M. Höckel, and P. Vaupel Biological consequences of tumor hypoxia Semin Oncol 28 2 suppl 8 2001 36 41
15. 2 tension Am J Physiol 271 1996 1172 1180
16. 2 tension Proc Natl Acad Sci USA 92 1995 5510 5514
17. C. Leo, J. Amato, A.J. Giaccia, and N.C. Denko The hypoxic tumor microenvironment and gene expression Semin Radiat Oncol 3 2004 207 214
18. P. Vaupel Role of tumor microenvironment in radiotherapy Semin Radiat Oncol 3 2004 198 206
19. T.G. Graeber, C. Osmanian, and T. Jacks Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours Nature 379 1996 88 91
20. T.Y. Reynolds, S. Rockwell, and P.M. Glazer Genetic instability induced by the tumor microenviroment Cancer Res 56 1996 5754 5757
21. J. Yuan, L. Narayanan, S. Rockwell, and P.M. Glazer Diminished DNA repair and elevated mutagenesis in mammalian cells exposed to hypoxia and low pH Cancer Res 60 2000 4372 4376
22. M. Henke, R. Laszig, and C. Rübe Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial Lancet 362 2003 1255 1260
23. P. Vaupel, O. Thews, A. Mayer, S. Hockel, and M. Hockel Oxygenation status of gynaecologic tumors: what is the optimal hemoglobin level? Strahlenther Onkol 178 2002 727 731