Efficient library synthesis of imidazoles using a multicomponent reaction and microwave irradiation

Molecular Diversity

Volumn 10, Issue 1, 2006, Pages 17-22

  Gelens, E ^a   De Kanter, F J J ^a   Schmitz, R F ^a   Sliedregt, L A J M ^b   Van Steen, B J ^b   Kruse, Chris G ^b   Leurs, R ^a   Groen, M B ^a   Orru, R V A ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b Solvay Pharmaceuticals Inc   (Netherlands)

Author keywords

Combinatorial chemistry; Diversity; Imidazoles; Library synthesis; Microwave; Multicomponent reaction

Indexed keywords

ALDEHYDE; AMINE; DIKETONE 1,2 PHENYLPROPANEDIONE; IMIDAZOLE DERIVATIVE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; MICROWAVE IRRADIATION; PRIORITY JOURNAL; SUBSTITUTION REACTION;

ALDEHYDES; COMBINATORIAL CHEMISTRY TECHNIQUES; IMIDAZOLES; KETONES; MICROWAVES; MOLECULAR STRUCTURE;

EID: 30744456749     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-006-8695-3     Document Type: Article

References (25)

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25. This was established by NOESY-NMR analysis.