Subunit communication in tetrameric class 2 human liver aldehyde dehydrogenase as the basis for half-of-the-site reactivity and the dominance of the oriental subunit in a heterotetramer

Chemico-Biological Interactions

Volumn 130-132, Issue , 2001, Pages 47-56

  Weiner, Henry ^a   Wei, Baoxian ^a   Zhou, Jianzhong ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Aldehyde dehydrogenase; Half of the site reactivity; Oriental variant; Structure; Subunit interaction

Indexed keywords

ALDEHYDE DEHYDROGENASE; ARGININE; COMPLEMENTARY DNA; GLUTAMINE; LIVER ENZYME; MUTANT PROTEIN; TETRAMER;

AMINO ACID SUBSTITUTION; CONFERENCE PAPER; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; HUMAN; NONHUMAN; STRUCTURE ANALYSIS;

ALDEHYDE DEHYDROGENASE; CATALYTIC DOMAIN; ESCHERICHIA COLI; HUMANS; KINETICS; MITOCHONDRIA, LIVER; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; VARIATION (GENETICS);

EID: 0035969886     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00221-0     Document Type: Conference Paper

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