Calcium oscillation and phosphatidylinositol 3-kinase positively regulate integrin αIIbβ3-mediated outside-in signaling

Journal of Biomedical Science

Volumn 12, Issue 2, 2005, Pages 321-333

  Sun, Der Shan ^a   Lo, Szecheng J ^b,c   Lin, Chi Hung ^c   Yu, Mei Shiuan ^a   Huang, Ching Yi ^a   Chen, Yao Fong ^a   Chang, Hsin Hou ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Calcium oscillation; Integrin IIb 3; Integrin outside in signaling; Phosphatidylinositol 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATASE INHIBITOR; ALPHA2 INTEGRIN; ARGINYLGLYCYLASPARTIC ACID; CALCIUM ION; DISINTEGRIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; THAPSIGARGIN; WORTMANNIN;

ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; ENZYME ACTIVATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; MICROSOME; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR DENSITY; THROMBOCYTE ACTIVATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANDROSTADIENES; BLOOD PLATELETS; CALCIUM; CHROMONES; CYTOSKELETON; HUMANS; IMMUNOPRECIPITATION; INTEGRINS; MICROSCOPY, CONFOCAL; MICROSCOPY, VIDEO; MODELS, BIOLOGICAL; MORPHOLINES; OLIGOPEPTIDES; OSCILLOMETRY; PEPTIDES; PHOSPHOLIPIDS; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 21244485323     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/s11373-005-0979-6     Document Type: Article

References (72)

1. R.O. Hynes 1992 Integrins: versatility, modulation, and signaling in cell adhesion Cell 69 11 25
2. R. Pytela M.D. Pierschbacher M.H. Ginsberg E.F. Plow E. Ruoslahti 1986 Platelet membrane glycoprotein IIb/IIIa: member of a family of Arg-Gly-Asp-specific adhesion receptors Science 231 1559 1562
3. E. Ruoslahti 1991 Integrins J. Clin. Invest. 87 1 5
4. H.H. Chang J.H. Kau S.J. Lo D.S. Sun 2003 Cell-adhesion and morphological changes are not sufficient to support anchorage-dependent cell growth via non-integrin-mediated attachment Cell Biol. Int. 27 123 133
5. H.H. Chang C.H. Lin S.J. Lo 1999 Recombinant rhodostomin substrates induce transformation and active calcium oscillation in human platelets Exp. Cell Res. 250 387 400
6. H.H. Chang S.J. Lo 1998 Full-spreading platelets induced by the recombinant rhodostomin are via binding to integrins and correlated with FAK phosphorylation Toxicon 36 1087 1099
7. W.B. Wu H.C. Peng T.F. Huang 2003 Disintegrin causes proteolysis of beta-catenin and apoptosis of endothelial cells. Involvement of cell-cell and cell-ECM interactions in regulating cell viability Exp. Cell. Res. 286 115 127
8. B. Payrastre K. Missy C. Trumel S. Bodin M. Plantavid H. Chap 2000 The integrin alpha IIb/beta 3 in human platelet signal transduction Biochem. Pharmacol. 60 1069 1074
9. E.A. Clark J.S. Brugge 1995 Integrins and signal transduction pathways: the road taken Science 268 233 239
10. M.A. Schwartz M.D. Schaller M.H. Ginsberg 1995 Integrins: emerging paradigms of signal transduction Annu. Rev. Cell. Dev. Biol. 11 549 599
11. Y. Chang T.L. Chen G.J. Wu G. Hsiao M.Y. Shen K.H. Lin D.S. Chou C.H. Lin J.R. Sheu 2004 Mechanisms involved in the antiplatelet activity of ketamine in human platelets J. Biomed. Sci. 11 764 772
12. E.A. Clark S.J. Shattil J.S. Brugge 1994 Regulation of protein tyrosine kinases in platelets Trends Biochem. Sci. 19 464 469
13. L. Lipfert B. Haimovich M.D. Schaller B.S. Cobb J.T. Parsons J.S. Brugge 1992 Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets J. Cell Biol. 119 905 912
14. B. Haimovich L. Lipfert J.S. Brugge S.J. Shattil 1993 Tyrosine phosphorylation and cytoskeletal reorganization in platelets are triggered by interaction of integrin receptors with their immobilized ligands J. Biol. Chem. 268 15868 15877
15. B. Haimovich N. Kaneshiki P. Ji 1996 Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen Blood 87 152 161
16. J.M. Heraud C. Racaud-Sultan D. Gironcel C. Albiges-Rizo T. Giacomini S. Roques V. Martel M. Breton-Douillon B. Perret H. Chap 1998 Lipid products of phosphoinositide 3-kinase and phosphatidylinositol 4′,5′- bisphosphate are both required for ADP-dependent platelet spreading J. Biol. Chem. 273 17817 17823
17. D.R. Phillips L. Nannizzi-Alaimo K.S. Prasad 2001 Beta3 tyrosine phosphorylation in alphaIIbbeta3 (platelet membrane GP IIb-IIIa) outside-in integrin signaling Thromb. Haemost. 86 246 258
18. S.J. Shattil H. Kashiwagi N. Pampori 1998 Integrin signaling: the platelet paradigm Blood 91 2645 2657
19. M.S. Kwon C.S. Park K. Choi J. Ahnn J.I. Kim S.H. Eom S.J. Kaufman W.K. Song 2000 Calreticulin couples calcium release and calcium influx in integrin-mediated calcium signaling Mol. Biol. Cell 11 1433 1443
20. A. Saci F. Rendu C. Bachelot-Loza 2000 Platelet alpha IIb-beta 3 integrin engagement induces the tyrosine phosphorylation of Cbl and its association with phosphoinositide 3-kinase and Syk Biochem. J. 351 Pt 3 669 676
21. C.D. Nobes A. Hall 1995 Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia Cell 81 53 62
22. A.J. Ridley A. Hall 1992 The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors Cell 70 389 399
23. A.J. Ridley H.F. Paterson C.L. Johnston D. Diekmann A. Hall 1992 The small GTP-binding protein rac regulates growth factor-induced membrane ruffling Cell 70 401 410
24. M. Mazzucato P. Pradella M.R. Cozzi L. De Marco Z.M. Ruggeri 2002 Sequential cytoplasmic calcium signals in a 2-stage platelet activation process induced by the glycoprotein Ibalpha mechanoreceptor Blood 100 2793 2800
25. W.S. Nesbitt S. Kulkarni S. Giuliano I. Goncalves S.M. Dopheide C.L. Yap I.S. Harper H.H. Salem S.P. Jackson 2002 Distinct glycoprotein Ib/V/IX and integrin alpha IIbbeta 3-dependent calcium signals cooperatively regulate platelet adhesion under flow J. Biol. Chem. 277 2965 2972
26. J.W. Heemskerk P. Vis M.A. Feijge J. Hoyland W.T. Mason S.O. Sage 1993 Roles of phospholipase C and Ca(2+)-ATPase in calcium responses of single, fibrinogen-bound platelets J. Biol. Chem. 268 356 363
27. J.F. Hussain M.P. Mahaut-Smith 1999 Reversible and irreversible intracellular Ca2+ spiking in single isolated human platelets J. Physiol. 514 Pt 3 713 718
28. M.E. Gracheva J.D. Gunton 2003 Intercellular communication via intracellular calcium oscillations J. Theor. Biol. 221 513 518
29. M.J. Berridge M.D. Bootman P. Lipp 1998 Calcium - a life and death signal Nature 395 645 648
30. M.J. Berridge P. Lipp M.D. Bootman 2000 The versatility and universality of calcium signalling Nat. Rev. Mol. Cell. Biol. 1 11 21
31. T.W. Chow J.D. Hellums J.L. Moake M.H. Kroll 1992 Shear stress-induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation Blood 80 113 120
32. C.L. Yap K.E. Anderson S.C. Hughan S.M. Dopheide H.H. Salem S.P. Jackson 2002 Essential role for phosphoinositide 3-kinase in shear-dependent signaling between platelet glycoprotein Ib/V/IX and integrin alpha(IIb) beta(3) Blood 99 151 158
33. H.H. Chang S.T. Hu T.F. Huang S.H. Chen Y.H. Lee S.J. Lo 1993 Rhodostomin, an RGD-containing peptide expressed from a synthetic gene in Escherichia coli, facilitates the attachment of human hepatoma cells Biochem. Biophys. Res. Commun. 190 242 249
34. H.H. Chang H.F. Shyu Y.M. Wang D.S. Sun R.H. Shyu S.S. Tang Y.S. Huang 2002 Facilitation of cell adhesion by immobilized dengue viral nonstructural protein 1 (NS1): arginine-glycine-aspartic acid structural mimicry within the dengue viral NS1 antigen J. Infect. Dis. 186 743 751
35. H.H. Chang W.J. Tsai S.J. Lo 1997 Glutathione S-transferase-rhodostomin fusion protein inhibits platelet aggregation and induces platelet shape change Toxicon 35 195 204
36. C. Heilmann S. Niemann B. Sinha M. Herrmann B.E. Kehrel G. Peters 2004 Staphylococcus aureus fibronectin-binding protein (FnBP)-mediated adherence to platelets, and aggregation of platelets induced by FnBPA but not by FnBPB J. Infect. Dis. 190 321 329
37. G. Hsiao M.Y. Shen D.S. Chou C.H. Lin T.F. Chen J.R. Sheu 2004 Involvement of the antiplatelet activity of magnesium sulfate in suppression of protein kinase C and the Na+/H+ exchanger J. Biomed. Sci. 11 19 26
38. G. Hsiao M.Y. Shen C.L. Fang D.S. Chou C.H. Lin T.F. Chen J.R. Sheu 2003 Morphine-potentiated platelet aggregation in in vitro and platelet plug formation in invitro experiments J. Biomed. Sci. 10 292 301
39. A.Y. Chang J.Y. Chan S.H. Chan 2003 Differential distribution of nitric oxide synthase isoforms in the rostral ventrolateral medulla of the rat J. Biomed. Sci. 10 285 291
40. S.S. Fan M.S. Chen J.F. Lin W.T. Chao V.C. Yang 2003 Use of gain-of-function study to delineate the roles of crumbs in Drosophila eye development J. Biomed. Sci. 10 766 773
41. N.K. Mak T.W. Kok R.N. Wong S.W. Lam Y.K. Lau W.N. Leung N.H. Cheung D.P. Huang L.L. Yeung C.K. Chang 2003 Photodynamic activities of sulfonamide derivatives of porphycene on nasopharyngeal carcinoma cells J. Biomed. Sci. 10 418 429
42. M. Gorka M.M. Godlewski B. Gajkowska U. Wojewodzka T. Motyl 2004 Kinetics of Smac/DIABLO release from mitochondria during apoptosis of MCF-7 breast cancer cells Cell. Biol. Int. 28 741 754
43. K.G. Lee T. Miller I. Anastassov W.D. Cohen 2004 Shape transformation and cytoskeletal reorganization in activated non-mammalian thrombocytes Cell Biol. Int. 28 299 310
44. L.M. Mascari J.M. Ross 2003 Quantification of staphylococcal-collagen binding interactions in whole blood by use of a confocal microscopy shear-adhesion assay J. Infect. Dis. 188 98 107
45. A. Oertel A. Holzinger U. Lutz-Meindl 2003 Involvement of myosin in intracellular motility and cytomorphogenesis in Micrasterias Cell Biol. Int. 27 977 986
46. K.E. Yates-Siilata T.E. Dahms R.O. Webster R.M. Heuertz 2004 C-reactive protein increases F-actin assembly and cortical distribution with resultant loss of lamellipod formation in human neutrophils Cell Biol. Int. 28 33 39
47. D.S. Sun H.H. Chang 2003 Differential regulation of JNK in caspase-3-mediated apoptosis of MPP(+)-treated primary cortical neurons Cell Biol. Int. 27 769 777
48. Y.L. Tseng H.C. Peng T.F. Huang 2004 Rhodostomin, a disintegrin, inhibits adhesion of neutrophils to fibrinogen and attenuates superoxide production J. Biomed. Sci. 11 683 691
49. Y.S. Kao J.C. Fong 2004 Thapsigargin and EGTA inhibit endothelin-1-induced glucose transport J. Biomed. Sci. 11 206 213
50. R.C. Carroll R.G. Butler P.A. Morris J.M. Gerrard 1982 Separable assembly of platelet pseudopodal and contractile cytoskeletons Cell 30 385 393
51. D. Dash M. Aepfelbacher W. Siess 1995 Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets J. Biol. Chem. 270 17321 17326
52. A.N. Carter R. Huang A. Sorisky C.P. Downes S.E. Rittenhouse 1994 Phosphatidylinositol 3,4,5-trisphosphate is formed from phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets Biochem. J. 301 Pt 2 415 420
53. S. Boitano E.R. Dirksen M.J. Sanderson 1992 Intercellular propagation of calcium waves mediated by inositol trisphosphate Science 258 292 295
54. 2+ waves in the longitudinal muscle layer of the murine large intestine in vitro J. Physiol. 543 233 253
55. R. Levi M. Samoilova A.I. Selverston 2003 Calcium signaling components of oscillating invertebrate neurons in vitro Neuroscience 118 283 296
56. T.E. Danciu R.M. Adam K. Naruse M.R. Freeman P.V. Hauschka 2003 Calcium regulates the PI3K-Akt pathway in stretched osteoblasts FEBS Lett. 536 193 197
57. J.C. Yarrow T. Lechler R. Li T.J. Mitchison 2003 Rapid de-localization of actin leading edge components with BDM treatment BMC Cell Biol. 4 5
58. M. Kuwahara M. Sugimoto S. Tsuji S. Miyata A. Yoshioka 1999 Cytosolic calcium changes in a process of platelet adhesion and cohesion on a von Willebrand factor-coated surface under flow conditions Blood 94 1149 1155
59. K. Kuwahara T. Kawai S. Mitsuyoshi Y. Matsuo H. Kikuchi S. Imajoh-Ohmi E. Hashimoto S. Inui M.D. Cooper N. Sakaguchi 1996 Cross-linking of B cell antigen receptor-related structure of pre-B cell lines induces tyrosine phosphorylation of p85 and p110 subunits and activation of phosphatidylinositol 3-kinase Int. Immunol. 8 1273 1285
60. I. Goncalves S.C. Hughan S.M. Schoenwaelder C.L. Yap Y. Yuan S.P. Jackson 2003 Integrin alpha IIb beta 3-dependent calcium signals regulate platelet-fibrinogen interactions under flow. Involvement of phospholipase C gamma 2 J. Biol. Chem. 278 34812 34822
61. J.W. Heemskerk J. Hoyland W.T. Mason S.O. Sage 1992 Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets Biochem. J. 283 Pt 2 379 383
62. J.M. Pasquet L. Quek C. Stevens R. Bobe M. Huber V. Duronio G. Krystal S.P. Watson 2000 Phosphatidylinositol 3,4,5-trisphosphate regulates Ca(2+) entry via btk in platelets and megakaryocytes without increasing phospholipase C activity EMBO J. 19 2793 2802
63. Y.S. Bae L.G. Cantley C.S. Chen S.R. Kim K.S. Kwon S.G. Rhee 1998 Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate J. Biol. Chem. 273 4465 4469
64. M. Falasca S.K. Logan V.P. Lehto G. Baccante M.A. Lemmon J. Schlessinger 1998 Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting EMBO J. 17 414 422
65. 2+ mobilization is integrated by CD19 dephosphorylation Immunity 7 49 58
66. M.D. Bootman M.J. Berridge 1995 The elemental principles of calcium signaling Cell 83 675 678
67. M.D. Bootman T.J. Collins C.M. Peppiatt L.S. Prothero L. MacKenzie P. De Smet M. Travers S.C. Tovey J.T. Seo M.J. Berridge F. Ciccolini P. Lipp 2001 Calcium signalling - an overview Semin. Cell. Dev. Biol. 12 3 10
68. G. Hajnoczky L.D. Robb-Gaspers M.B. Seitz A.P. Thomas 1995 Decoding of cytosolic calcium oscillations in the mitochondria Cell 82 415 424
69. S. Kulkarni S.M. Dopheide C.L. Yap C. Ravanat M. Freund P. Mangin K.A. Heel A. Street I.S. Harper F. Lanza S.P. Jackson 2000 A revised model of platelet aggregation J. Clin. Invest. 105 783 791
70. V. Fuster L. Badimon J.J. Badimon J.H. Chesebro 1992 The pathogenesis of coronary artery disease and the acute coronary syndromes (1) New Engl. J. Med. 326 242 250
71. V. Fuster L. Badimon J.J. Badimon J.H. Chesebro 1992 The pathogenesis of coronary artery disease and the acute coronary syndromes (2) New Engl. J. Med. 326 310 318
72. 2+ signal generation Thromb. Haemost. 88 931 937