Emergence of community-associated methicillin-resistant Staphylococcus aureus in Singapore: A further six cases

Singapore Medical Journal

Volumn 47, Issue 1, 2006, Pages 20-26

  Hsu, Li Yang ^a   Koh, T H ^a   Tan, T Y ^b   Ito, T ^c   Ma, X X ^c   Lin, R T ^d   Tan, B H ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

^b CHANGI GENERAL HOSPITAL   (Singapore)

^c JUNTENDO UNIVERSITY   (Japan)

^d KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

Author keywords

Community infection; Methicillin resistance; Methicillin resistant Staphylococcus aureus; Panton Valentine leukocidin; Staphylococcus aureus

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; CIPROFLOXACIN; CLINDAMYCIN; CLOXACILLIN; COTRIMOXAZOLE; ERYTHROMYCIN; FUSIDIC ACID; GENTAMICIN; METICILLIN; OXACILLIN; TETRACYCLINE; VANCOMYCIN;

ABSCESS DRAINAGE; ADULT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIAL GENE; BACTERIUM ISOLATE; CHILD; CHRONIC OSTEOMYELITIS; CLINICAL ARTICLE; CLINICAL FEATURE; FEMALE; HUMAN; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR EPIDEMIOLOGY; NONHUMAN; PULSED FIELD GEL ELECTROPHORESIS; PVL GENE; SINGAPORE; SKIN ABSCESS;

ADULT; BACTERIAL TOXINS; BACTERIAL TYPING TECHNIQUES; CHILD; CHROMOSOMES, BACTERIAL; COMMUNITY-ACQUIRED INFECTIONS; ELECTROPHORESIS, GEL, PULSED-FIELD; EXOTOXINS; FEMALE; GENES, BACTERIAL; HUMANS; LEUKOCIDINS; MALE; METHICILLIN RESISTANCE; MIDDLE AGED; SINGAPORE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 30544444354     PISSN: 00375675     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Jevons MP, Coe AW, Parker MT. Methicillin resistance in staphylococci. Lancet 1963; 1:904-7.
2. Fuda C, Suvorov M, Vakulenko SB, Mobashery S. The basis for resistance to β-lactam antibiotics by penicillin-binding protein 2a (PBP2a) of methicillin-resistant Staphylococcus aureus. J Biol Chem 2004; 279:40802-6.
3. Katayama Y, Ito T, Hiramatsu K. A new class of genetic element, staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother 2000; 44:1549-55.
4. Ito T, Ma XX, Takeuchi F, Okuma K, et al. Novel type V staphylococcal chromosome cassette mec driven by a novel cassette chromosome recombinase, ccrC. Antimicrob Agents Chemother 2004; 48:2637-51.
5. Hiramatsu K, Cui L, Kuroda M, Ito T. The emergence and evolution of methicillin resistant Staphylococcus aureus. Trends Microbiol 2001; 9:486-93.
6. Enright MC, Robinson DA, Randle G, et al. The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA). Proc Natl Acad Sci USA. 2002; 99:7687-92.
7. Esuvaranathan K, Kuan YF, Kumarasinghe G, et al. A study of 245 infected wounds in Singapore. J Hosp Infect 1992; 21:231-40.
8. Hsu LY, Koh TH, Singh KS, et al. Dissemination of multisusceptible methicillin-resistant Staphylococcus aureus in Singapore. J Clin Microbiol 2005; 43:2923-5.
9. CDC. Community-acquired methicillin-resistant Staphylococcus aureus infections-Michigan. MMWR Morb Mortal Wkly Rep 1981; 30:185-7.
10. Udo EE, Pearman, JW, Grubb WB. Genetic analysis of community isolates of methicillin-resistant Staphylococcus aureus in Western Australia. J Hosp Infect 1993; 25:97-108.
11. Herold BC, Immergluck LC, Maranan MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA 1998; 279:593-8.
12. Dufour P, Gillet Y, Bes M, et al. Community-acquired methicillin- resistant Staphylococcus aureus infections in France: emergence of a single clone that produces Panton-Valentine leukocidin. Clin Infect Dis 2002; 35:819-24.
13. Okuma K, Iwakawa K, Turnidge JD, et al. Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community. J Clin Microbiol 2002; 40:4289-94.
14. Adhikari RP, Cook GM, Lamont I, et al. Phenotypic and molecular characterization of community occurring, Western Samoan phage pattern methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 2002; 50:825-31.
15. CDC. Community-associated methicillin-resistant Staphylococcus aureus in Pacific Islanders - Hawaii, 2001-2003. MMWR Morb Mortal Wkly Rep 2004; 53:767-70.
16. Wang CC, Lo WT, Chu ML, Siu LK. Epidemiological typing of community-acquired methicillin-resistant Staphylococcus aureus isolates from children in Taiwan. Clin Infect Dis 2004; 39:481-7.
17. Ho PL, Tse CW, Mak GC, et al. Community-acquired methicillin-resistant Staphylococcus aureus arrives in Hong Kong. J Antimicrob Chemother 2004; 54:845-6.
18. Young DM, Harris HW, Charlebois ED, et al. An epidemic of methicillin-resistant Staphylococcus aureus soft tissue infections among medically undeserved patients. Arch Surg 2004; 139:947-51.
19. CDC. Methicillin-resistant Staphylococcus aureus infections in correctional facilities - Georgia, California, and Texas, 2001-2003. MMWR Morb Mortal Wkly Rep 2003; 52:992-6.
20. Naimi TS, LeDell KH, Como-Sabetti K, et al. Comparison of community- and healthcare-associated methicillin-resistant Staphylococcus aureus infection. JAMA 2003; 290:2976-84.
21. Ma XX, Ito T, Tiensasitorn C, et al. Novel type of staphylococcal chromosome cassette mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains. Antimicrob Agents Chemother 2002; 46:1147-52.
22. Vandenesch F, Naimi T, Enright MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis 2003; 9:978-84.
23. O'Brien FG, Lim TT, Chong FN, et al. Diversity among community isolates of methicillin-resistant Staphylococcus aureus in Australia. J Clin Microbiol 2004; 42:3185-90.
24. Chambers HF. The changing epidemiology of Staphylococcus aureus? Emerg Infect Dis 2001; 7:178-82.
25. Hsu LY, Tristan A, Koh TH, et al. Community-associated methicillin-resistant Staphylococcus aureus, Singapore. Emerg Infect Dis 2005; 11:341-2.
26. National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. Wayne, PA: The Committee; 2004. NCCLS document M100-S14. vol 24, no 1.
27. Lina G, Piemont Y, Godail-Gamot F, et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999; 29:1128-32.
28. Oliveira DC, de Lencastre H. Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2002; 46:2155-61.
29. Maslow J, Slutsky A, Arbeit R. The application of pulsed field gel electrophoresis to molecular epidemiology. In: Persing H, Smith T, Tenover F, White T, eds. Diagnostic Molecular Microbiology: Principles and Applications. Washington, DC: American Society for Microbiology. 1993: 563-72.
30. Enright MC, Day NP, Davies CE, et al. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-sensitive clones of Staphylococcus aureus. J Clin Microbiol 2000; 38:1008-15.
31. Staphylococcus aureus multilocus sequence typing database. Available at: www.saureus.mlst.net/ Accessed October 15, 2004.
32. Nimmo GR, Schooneveldt J, O'Kane G, et al. Community acquisition of gentamicin-susceptible methicillin-susceptible Staphylococcus aureus in Southeast Queensland, Australia. J Clin Microbiol 2000; 38:3926-31.
33. Urth T, Juul G, Skov R, Schonheyder HC. Spread of a methicillin-resistant Staphylococcus aureus ST80-IV clone in a Danish community. Infect Control Hosp Epidemiol 2005; 25:144-9.
34. Murray RJ, Lim TT, Pearson JC, et al. Community-onset methicillin-resistant Staphylococcus aureus bacteremia in Northern Australia. Int J Infect Dis 2004; 8:275-83.
35. Buescher ES. Community-acquired methicillin-resistant Staphylococcus aureus in pediatrics. Curr Opin Pediatr 2005; 17:67-70.
36. Hsu LY, Koh TH, Kurup A, et al. High incidence of Panton Valentine leukocidin-producing Staphylococcus aureus in a tertiary public hospital in Singapore. Clin Infect Dis 2005; 40:486-9.
37. Charlebois ED, Bangsberg DR, Moss NJ, et al. Population-based community prevalence of methicillin-resistant Staphylococcus aureus in the urban poor of San Francisco. Clin Infect Dis 2002; 34:425-33.
38. Tanaka M, Wang T, Onodera Y, et al. Mechanism of quinolone resistance in Staphylococcus aureus. J Infect Chemother 2000; 6:131-9.