High incidence of Panton-Valentine leukocidin-producing Staphylococcus aureus in a tertiary care public hospital in Singapore

Clinical Infectious Diseases

Volumn 40, Issue 3, 2005, Pages 486-489

  Hsu, Li Yang ^a   Koh, Tse Hsien ^a   Kurup, Asok ^a   Low, Jenny ^a   Chlebicki, Maciej Piotr ^a   Tan, Ban Hock ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CLINDAMYCIN; CLOXACILLIN; COTRIMOXAZOLE; ERYTHROMYCIN; FUSIDATE SODIUM; GENTAMICIN; METICILLIN; PANTON VALENTINE LEUKOCIDIN; PENICILLIN G; STAPHYLOCOCCUS TOXIN; TETRACYCLINE; UNCLASSIFIED DRUG; VANCOMYCIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATION; CHILD; CONTROLLED STUDY; FEMALE; HUMAN; INCIDENCE; INFANT; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; PREVALENCE; PRIORITY JOURNAL; PUBLIC HOSPITAL; SINGAPORE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTERIAL TOXINS; CHILD; CHILD, PRESCHOOL; EXOTOXINS; FEMALE; HOSPITALS; HUMANS; INFANT; INFANT, NEWBORN; LEUKOCIDINS; MALE; METHICILLIN RESISTANCE; MIDDLE AGED; SINGAPORE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 13444310419     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/427033     Document Type: Article

References (11)

1. Ferreras M, Hoper F, Dalla Serra M, Colin DA, Prevost G, Menestrina G. The interaction of Staphylococcus aureus bi-component gamma-hemolysins and leucocidins with cells and lipid membranes. Biochim Biophys Acta 1998; 1414:108-26.
2. Prevost G, Couppie P, Prevost P, et al. Epidemiological data on Staphylococcus aureus strains producing synergohymenotropic toxins. J Med Microbiol 1995; 42:237-45.
3. Lina G, Piemont Y, Godail-Gamot F, et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999; 29:1128-32.
4. Vandenesch F, Naimi T, Enright MC, et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis 2003; 9:978-84.
5. Hsu LY, Koh TH, Anantham D, Chan KP, Kurup A, Tan BH. Panton-Valentine leukocidin-positive Staphylococcus aureus, Singapore. Emerg Infect Dis 2004; 10:1509-10.
6. NCCLS. Performance standards for antimicrobial susceptibility testing: 14th informational supplement. NCCLS document M100-S14. Wayne, PA: NCCLS, 2004.
7. Nakatomi Y, Sugiyama J. A rapid latex agglutination assay for the detection of penicillin-binding protein 2′. Microbiol Immunol 1998; 42:739-43.
8. Maslow J, Slutsky A, Arbeit R. The application of pulsed field gel electrophoresis to molecular epidemiology. In: Persing H, Smith T, Tenover F, White T, eds. Diagnostic molecular microbiology: principles and applications. Washington, DC: American Society for Microbiology Press, 1993:563-72.
9. Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995; 33:2233-9.
10. Tambyah PA, Habib AG, Ng TM, Goh H, Kumarasinghe G. Community-acquired methicillin-resistant Staphylococcus aureus infection in Singapore is usually "healthcare associated." Infect Control Hosp Epidemiol 2003; 24:436-8.
11. Boubaker K, Diebold P, Blanc DS, et al. Panton-valentine leukocidin and staphylococcal skin infections in schoolchildren. Emerg Infect Dis 2004; 10:121-4.