Vitamin E status in patients with liver cirrhosis: Normal or deficient?

Metabolism: Clinical and Experimental

Volumn 48, Issue 1, 1999, Pages 86-91

  Look, Markus P ^a   Reichel, Christoph ^b   Von Falkenhausen, Marcus ^b   Hahn, Corinna ^b   Stockinger, Klaus ^b   Von Bergmann, Klaus ^b   Rao, Govind S ^b   Spengler, Ulrich ^b   Sauerbruch, Tilman ^b  

^a UNIVERSITY OF BONN   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

7ALPHA HYDROXYCHOLESTEROL; ALPHA TOCOPHEROL;

ADULT; AGED; ALPHA TOCOPHEROL DEFICIENCY; ARTICLE; CHOLESTEROL BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTHROMBIN TIME; VITAMIN BLOOD LEVEL;

EID: 0032902652     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(99)90015-X     Document Type: Article

References (50)

1. Traber M, Sies H: Vitamin E in humans: Demand and delivery. Annu Rev Nutr 16:321-347, 1996
2. Sies H: Oxidative stress: From basic research to clinical application. Am J Med 91:31-38, 1991
3. Stead R, Muller D, Matthews S, et al: Effect of abnormal liver function on vitamin E status and supplementation in adults with cystic fibrosis. Gut 27:714-718, 1986
4. Muller D, Lloyd J, Wolf O: Vitamin E and neurological function. Lancet 29:225-228, 1983
5. Sokol R, Heubi J, Lannaccone S, et al: Vitamin E deficiency with normal serum vitamin E concentrations in children with chronic cholestasis. N Engl J Med 310:1209-1212, 1984
6. Gotoda T, Arita M, Arai H, et al: Adult-onset spinocerebellar dysfunction caused by a mutation in the gene for the alpha-tocopherol-transfer protein. N Engl J Med 33:1313-1318, 1995
7. Horowitt M, Harvey C, Dahm C, et al: Relationship between tocopherol and serum lipid levels for determination of nutritional adequacy. Ann NY Acad Sci 203:223-236, 1972
8. Bell H, Bjorneboe A, Eidsvoll B, et al: Reduced concentration of hepatic alpha tocopherol in patients with alcoholic liver cirrhosis. Alcohol Alcohol 27:39-46, 1992
9. von Herbay A, de Groot H, Hegi U, et al: Low vitamin E content in plasma of patients with alcoholic liver disease, hemochromatosis and Wilson's disease. J Hepatol 20:41-46, 1994
10. von Herbay A, Stremmel W, de Groot H, et al: Antioxidant deficiency in patients with chronic liver disease, in Holstege H, Schölmerich P (eds): Portal Hypertension, Fakl Symposium 79. Dordrecht, The Netherlands, Kluwer Academic, 1995, pp 147-154
11. Jeffrey G, Muller D, Burroughs A, et al: Vitamin E deficiency and its clinical significance in adults with primary biliary cirrhosis and other forms of chronic liver disease. J Hepatol 4:307-317, 1987
12. Leo M, Rosman A, Lieber C: Differential depletion of carotinoids and tocopherol in liver disease. Hepatology 17:977-986, 1993
13. Lu W, Bantok I, Desai S, et al: Aminoterminal procollagen III peptide elevation in alcoholics who are selenium and vitamin E deficient. Clin Chim Acta 154:165-170, 1986
14. Rocchi E, Borghi A, Paolillo F, et al: Carotinoids and lipid soluble vitamins in liver cirrhosis. J Lab Clin Med 118:176-185, 1991
15. Sokol R, Kim Y, Hoofnagle J, et al: Intestinal malabsorption of vitamin E in primary biliary cirrhosis. Gastroenterology 96:479-486, 1989
16. Lewis L, Quaife M, Page I: Lipoproteins of serum, carriers of tocopherol. Am J Physiol 187:221-222, 1954
17. Turnham D, Davies J, Crump B, et al: The use of different lipids to express serum tocopherol: Lipid ratios for the measurement of vitamin E status. Ann Clin Biochem 23:514-520, 1986
18. Davies T, Kelleher J, Lososwsky M: Interrelation of serum lipoprotein and tocopherol levels. Clin Chim Acta 24:431-436, 1968
19. McCormic E, Cornwell D, Brown J: Studies on the distribution of tocopherol in human serum lipoproteins. J Lipid Res 1:221-228, 1960
20. Sokol R, Balistreri W, Hoofnagle J, et al: Vitamin E deficiency in adults with chronic liver disease. Am J Clin Nutr 41:66-72, 1985
21. von Herbay A, Stahl W, Niederau C, et al: Diminished plasma levels of vitamin E in patients with severe viral hepatitis. Free Radic Res 25:461-466, 1996
22. Binder H, Herting D, Hurst V, et al: Tocopherol deficiency in man. N Engl J Med 273:1289-1297, 1965
23. Punchard N, Senturk H, Teare J, et al: Resistance of erythrocytes to lipid peroxidation in alcoholic patients. Gut 35:1753-1756, 1994
24. Poli G, Parola M: Oxidative damage and fibrogenesis. Free Radie Biol Med 22:287-305, 1997
25. Gressner A, Bachern M: Molecular mechanisms of liver fibrogenesis - A homage to the role of activated fat-storing cells. Digestion 56:335-346, 1995
26. Bedossa P, Houglum K, Trautwein C, et al: Stimulation of collagen alpha 1 gene expression is associated with lipid peroxidation in hepatocellular injury: A link to tissue fibrosis? Hepatology 19:1262-1271, 1994
27. Britton R, Bacon B: Role of free radicals in liver diseases and hepatic fibrosis. Hepatogastroenterology 41:343-348, 1994
28. Casini A, Ceni E, Salzano R, et al: Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: Role of nitric oxide. Hepatology 25:361-367, 1997
29. Liu S, Esposti S, Yao T, et al: Vitamin E therapy of acute CC14-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. Hepatology 22:1474-1481, 1996
30. Houglum K, Brenner D, Chojkier M: D-Alpha-tocopherol inhibits collagen alpha 1(1) gene expression in cultured human fibroblasts. J Clin Invest 87:2230-2235, 1991
31. Parola M, Muraca R, Dianzani I, et al: Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver. FEBS Lett 208:267-270, 1992
32. Pietrangelo A, Gualdi R, Casalgrandi G, et al: Molecular and cellular aspects of iron-induced hepatic cirrhosis in rodents. J Clin Invest 96:1824-1831, 1995
33. Manna Z, Guopei S, Minuk G: Effects of hepatic stimulator substance, herbal medicine, selenium/vitamin E and ciprofloxacin on cirrhosis in the rat. Gastroenterology 110:1150-1155, 1996
34. Traber M, Packer L: Vitamin E beyond antioxidant function. Am J Clin Nutr 62:1501S-1509S, 1995 (suppl)
35. de-la Maza M, Petermann M, Bunout D, et al: Effects of long-term vitamin E supplementation in alcoholic cirrhotics. J Am Coll Nutr 14:192-196, 1995
36. Sokol R: Antioxidant defenses in metal-induced liver damage. Semin Liver Dis 16:39-46, 1996
37. Houglum K, Venkataramani A, Lyche K, et al: A pilot study of the effects of D-alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C. Gastroenterology 113:1069-1073, 1997
38. Cicognani C, Malavolti M, Morselli-Labate A, et al: Serum lipid and lipoprotein patterns in patients with liver cirrhosis and chronic active hepatitis. Arch Intern Med 157:792-796, 1997
39. Kuroki S, Okamoto S, Naito T, et al: Serum 7a-hydroxycholesterol as a new parameter of liver function in patients with chronic liver disease. Hepatology 22:1182-1187, 1995
40. Rondana M, Milani L, Merkel C, et al: Value of prealbumin plasma levels as liver test. Digestion 37:72-78, 1989
41. Child CG, Turcotte JG: Surgery and portal hypertension, in Child CG (ed): The Liver and Portal Hypertension. Philadelphia, PA, Saunders, 1964, pp 50-51
42. Hahn C, Reichel C, von Bergmann K: Serum concentration of 7 alpha-hydroxycholesterol as an indicator of bile acid synthesis in humans. J Lipid Res 36:2059-2066, 1995
43. Nagita A, Ando M: Assessment of hepatic vitamin E status in adult patients with liver disease. Hepatology 26:392-397, 1997
44. Göransson G, Nordén Å, Åkesson B: Low plasma tocopherol levels in patients with gastrointestinal disorders. Scand J Gastroenterol 8:21-25, 1973
45. Yoshikawa T, Takemura S, Kondo M: Alpha tocopherol in liver disease. Acta Vitaminol Enzymol 4:311-318, 1982
46. Munoz S, Heubi J, Balisteri W, et al: Alpha-tocopherol deficiency in primary biliary cirrhosis: Gastrointestinal malabsorption, frequency and relationship to other lipid soluble vitamins. Hepatology 9:525-531, 1989
47. Reichel C, Sauerbruch T: Serum bile acids: Physiology and clinical relevance. Eur J Gastroenterol Hepatol 7:951-953, 1995
48. Clot P, Tabone M, Arico S, et al: Monitoring oxidative damage in patients with liver cirrhosis and different daily alcohol intake. Gut 35:1637-1643, 1994
49. Traber M: Determinants of plasma vitamin E concentrations. Free Radic Biol Med 16:229-239, 1994
50. Stone W, Papas A: Tocopherols and the etiology of colon cancer. J Natl Cancer Inst 89:1006-1014, 1997