Prevention of ischemia-reperfusion-induced hepatic microcirculatory disruption by inhibiting stellate cell contraction using rock inhibitor

Transplantation

Volumn 75, Issue 5, 2003, Pages 579-586

  Mizunuma, Kazuyuki ^a   Ohdan, Hideki ^a   Tashiro, Hirotaka ^a   Fudaba, Yasuhiro ^a   Ito, Hisao ^b   Asahara, Toshimasa ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; AMINOTRANSFERASE; CELL PROTEIN; CYTOCHROME C OXIDASE; DEOXYHEMOGLOBIN; ENDOTHELIN 1; ENZYME INHIBITOR; RHO ASSOCIATED COILED COIL FORMING PROTEIN SERINE THREONINE KINASE; RHO KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DISRUPTION; CELL ISOLATION; CELL MOTILITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DOSE RESPONSE; GRAFT SURVIVAL; ISCHEMIA; LIVER CIRCULATION; LIVER GRAFT; LIVER SINUSOID; LIVER TRANSPLANTATION; MALE; MICROCIRCULATION; MITOCHONDRIAL RESPIRATION; NEAR INFRARED SPECTROSCOPY; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; RAT; RECIPIENT; REPERFUSION INJURY; STELLATE CELL;

AMIDES; ANIMALS; CELLS, CULTURED; ENDOTHELIN-1; ENDOTHELIUM; ENZYME INHIBITORS; ENZYMES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISCHEMIA; LIVER; LIVER CIRCULATION; LIVER FAILURE; LIVER TRANSPLANTATION; MALE; MICROCIRCULATION; MITOCHONDRIA, LIVER; OXYGEN CONSUMPTION; PROTEIN-SERINE-THREONINE KINASES; PYRIDINES; RATS; RATS, WISTAR; REPERFUSION INJURY;

EID: 0037444114     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000052593.16876.AF     Document Type: Article

References (30)

1. Jaeschke H. Reactive oxygen and ischemia/reperfusion injury of the liver. Chem Biol Interact 1991; 79: 115.
2. Wanner GA, Ertel W, Muller P, et al. Liver ischemia and reperfusion induces a systemic inflammatory response through Kupffer cell activation. Shock 1996; 5: 34.
3. Thiel M, Imendorffer S, Chouker A, et al. Expression of adhesion molecules on circulating polymorphonuclear leukocytes during orthotopic liver transplantation. Hepatology 1998; 28; 1538.
4. Yokoi Y, Namihisa T, Kuroda H, et al. Immunocytochemical detection of desmin in fat-storing cells (Ito cells). Hepatology 1984; 4: 709.
5. Zhang JX, Bauer M, Clemens MG. Vessel- and target cell-specific actions of endothelin-1 and endothelin-3 in rat liver. Am J Physiol 1995; 269: G269.
6. Ankoma-Sey V, Wang Y, Dai Z. Hypoxic stimulation of vascular endothelial growth factor expression in activated rat hepatic stellate cells. Hepatology 2000; 31: 141.
7. Hirose M, Ishizaki T, Watanabe N, et al. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J Cell Biol 1998; 141: 1625.
8. Maekawa M, Ishizaki T, Boku S, et al. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 1999; 285: 895.
9. Ishizaki T, Uehata M, Tamechika I, et al. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol Pharmacol 2000; 57: 976.
10. Kawada N, Seki S, Kuroki T, et al. ROCK inhibitor Y-27632 attenuates stellate cell contraction and portal pressure increase induced by endothelin-1. Biochem Biophys Res Commun 1999; 266: 296.
11. Kawada N, Tran-Thi TA, Klein H, et al. The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances: possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur J Biochem 1993; 213: 815.
12. Rockey DC, Housset CN, Friedman SL. Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo. J Clin Invest 1993; 92: 1795.
13. Jobsis-VanderVliet FF, Piantadosi CA, Sylvia AL, et al. Near-infrared monitoring of cerebral oxygen sufficiency. I. Spectra of cytochrome c oxidase. Neurol Res 1988; 10: 7.
14. Ohdan H, Fukuda Y, Suzuki S, et al. Simultaneous evaluation of nitric oxide synthesis and tissue oxygenation in rat liver allograft rejection using near-infrared spectroscopy. Transplantation 1995; 60: 530.
15. Noriyuki T, Ohdan H, Yoshioka S, et al. Near-infrared spectroscopic method for assessing the tissue oxygenation state of living lung. Am J Respir Crit Care Med 1997; 156: 1656.
16. Kamada N, Calne RY. Orthotopic liver transplantation in the rat: technique using cuff for portal vein anastomosis and biliary drainage. Transplantation 1979; 28: 47.
17. Sakamoto M, Ueno T, Kin M, et al. Ito cell contraction in response to endothelin-1 and substance P. Hepatology 1993; 18: 978.
18. Sutto F, Brault A, Lepage R, et al. Metabolism of hyaluronic acid by liver endothelial cells: effect of ischemia-reperfusion in the isolated perfused rat liver. J Hepatol 1994; 20: 611.
19. Tanikawa K, Ueno T. Intrinsic innervation and Ito cells in human liver. In: Tsuchiya M, Nagura H, Hibe T, Moro I, eds. Frontiers of mucosal immunology, vol. 2. New York, Excerpta Medica 1991, p 179.
20. 2+ sensitivity in alpha-toxin-permeabilized rabbit mesenteric artery. Circ Res 1992; 71: 951.
21. Yanagisawa M. The endothelin system: a new target for therapeutic intervention. Circulation 1994; 89: 1320.
22. Rockey DC. Characterization of endothelin receptors mediating rat hepatic stellate contraction. Biochem Biophys Res Commun 1995; 207: 725.
23. Weir EK, Archer SL. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J 1995; 9: 183.
24. 2+ sensitization of smooth muscle. Proc Natl Acad Sci USA 1996; 93: 1340.
25. Kimura K, Ito M, Amano M, et al. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase). Science 1996; 273: 245.
26. Uehata M, Ishizaki T, Sato H, et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997; 389: 990.
27. Nauta RJ, Tsimoyiannis E, Uribe M, et al. The role of calcium ions and calcium channel entry blockers in experimental ischemia-reperfusion-induced liver injury. Ann Surg 1991; 213: 137.
28. Kitayama Y, Yamanaka N, Kawamura E, et al. Hepatoprotective effect of the endothelin receptor antagonist TAK-044 against ischemia-reperfusion injury in the canine liver. Hepatology 1997; 25: 938.
29. Anderson SI, Hotchin NA, Nash GB. Role of the cytoskeleton in rapid activation of CD11b/CD18 function and its subsequent downregulation in neutrophils. J Cell Sci 2000; 113: 2737.
30. Worthylake RA, Lemoine S, Watson JM, et al. RhoA is required for monocyte tail retraction during transendothelial migration. J Cell Biol 2001; 154: 147.