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Volumn 147, Issue SUPPL. 1, 2006, Pages

Antiarrhythmic drug research

Author keywords

Antiarrhythmic drugs; Classification; History; Mechanisms

Indexed keywords

ADENOSINE; ADRENERGIC RECEPTOR BLOCKING AGENT; AMIODARONE; ANTIANGINA PECTORIS AGENT; ANTIARRHYTHMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARDIAC GLYCOSIDE; DISOPYRAMIDE; LIDOCAINE; PHENYTOIN; POTASSIUM CHANNEL BLOCKING AGENT; PROCAINAMIDE; PROPRANOLOL; QUINIDINE; SODIUM CHANNEL BLOCKING AGENT; VERAPAMIL;

EID: 30444441408     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706500     Document Type: Review
Times cited : (14)

References (37)
  • 1
    • 0020644481 scopus 로고
    • Effects of prostaglandin E2, propranolol and nitroglycerine with halothane, pethidine or pentobarbitone anaethesia on arrhythmias and other responses to ligation of a coronary artery in rats
    • AU, T.L.S., COLLINS, G.A., MACLEOD, B.A. & WALKER, M.J.A. (1983). Effects of prostaglandin E2, propranolol and nitroglycerine with halothane, pethidine or pentobarbitone anaethesia on arrhythmias and other responses to ligation of a coronary artery in rats. Br. J. Pharmacol., 79, 929-937.
    • (1983) Br. J. Pharmacol. , vol.79 , pp. 929-937
    • Au, T.L.S.1    Collins, G.A.2    Macleod, B.A.3    Walker, M.J.A.4
  • 2
    • 0036191205 scopus 로고    scopus 로고
    • Proarrhythmic potential of halofantrine, terfenadine and clofilium in a modified in vivo model of torsades de pointes
    • BATEY, A.J. & COKER, S.J. (2002). Proarrhythmic potential of halofantrine, terfenadine and clofilium in a modified in vivo model of torsades de pointes. Br. J. Pharmacol., 135, 1003-1012.
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 1003-1012
    • Batey, A.J.1    Coker, S.J.2
  • 3
    • 0025855192 scopus 로고
    • Antiarrhythmic properties of tedisamil (KC8857), a putative transient outward K+ current blocker
    • BEATCH, G.N., ABRAHAM, S., MACLEOD, B.A., YOSHIDA, N.R. & WALKER, M.J.A. (1991). Antiarrhythmic properties of tedisamil (KC8857), a putative transient outward K+ current blocker. Br. J. Pharmacol., 102, 13-18.
    • (1991) Br. J. Pharmacol. , vol.102 , pp. 13-18
    • Beatch, G.N.1    Abraham, S.2    Macleod, B.A.3    Yoshida, N.R.4    Walker, M.J.A.5
  • 4
    • 0036790560 scopus 로고    scopus 로고
    • Interaction of different potassium channels in cardiac repolarization in dog ventricular preparations: Role of repolarization reserve
    • BILICZKI, P., VIRÁG, L., IOST, N., PAPP, J.G. & VARRÓ, A. (2002). Interaction of different potassium channels in cardiac repolarization in dog ventricular preparations: role of repolarization reserve. Br. J. Pharmacol., 137, 361-368.
    • (2002) Br. J. Pharmacol. , vol.137 , pp. 361-368
    • Biliczki, P.1    Virág, L.2    Iost, N.3    Papp, J.G.4    Varró, A.5
  • 5
    • 0038630449 scopus 로고    scopus 로고
    • Effects of flecainide and quinidine on Kv4.2 currents: Voltage dependence and role of S6 valines
    • CABALLERO, R., FOURRIER, M., SCHRAM, G., DELPÓN, E., TAMARGO, J. & NATTEL, S. (2003). Effects of flecainide and quinidine on Kv4.2 currents: voltage dependence and role of S6 valines. Br. J. Pharmacol., 138, 1475-1484.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 1475-1484
    • Caballero, R.1    Fourrier, M.2    Schram, G.3    Delpón, E.4    Tamargo, J.5    Nattel, S.6
  • 6
    • 0020064244 scopus 로고
    • Electrophysiological and other effects on rabbit hearts of CCI22277, a new steroidal antiarrhythmic drug
    • CAMPBELL, T.J. & VAUGHAN WILLIAMS, E.M. (1982). Electrophysiological and other effects on rabbit hearts of CCI22277, a new steroidal antiarrhythmic drug. Br. J. Pharmacol., 76, 337-345.
    • (1982) Br. J. Pharmacol. , vol.76 , pp. 337-345
    • Campbell, T.J.1    Vaughan Williams, E.M.2
  • 7
    • 0024321898 scopus 로고
    • Preliminary reports of the effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction
    • CAST INVESTIGATORS (1989). Preliminary reports of the effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N. Engl. J. Med., 321, 406-412.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 406-412
  • 8
    • 0036898840 scopus 로고    scopus 로고
    • The isolated blood-perfused rat heart: An inappropriate model for the study of ischaemia- and infarction-related ventricular fibrillation
    • CLEMENTS-JEWERY, H., HEARSE, D.J. & CURTIS, M.J. (2002). The isolated blood-perfused rat heart: an inappropriate model for the study of ischaemia- and infarction-related ventricular fibrillation. Br. J. Pharmacol., 137, 1089-1099.
    • (2002) Br. J. Pharmacol. , vol.137 , pp. 1089-1099
    • Clements-Jewery, H.1    Hearse, D.J.2    Curtis, M.J.3
  • 9
    • 0021178560 scopus 로고
    • Anti-arrhythmic actions of verapamil against ischaemic arrhythmias in the rat
    • CURTIS, M.J., MACLEOD, B.A. & WALKER, M.J.A. (1984). Anti-arrhythmic actions of verapamil against ischaemic arrhythmias in the rat. Br. J. Pharmacol., 83, 373-385.
    • (1984) Br. J. Pharmacol. , vol.83 , pp. 373-385
    • Curtis, M.J.1    Macleod, B.A.2    Walker, M.J.A.3
  • 10
    • 0022405419 scopus 로고
    • The effects of ablations in the central nervous system on arrhythmias induced by coronary occlusion in the rat
    • CURTIS, M.J., MACLEOD, B.A. & WALKER, M.J. (1985). The effects of ablations in the central nervous system on arrhythmias induced by coronary occlusion in the rat. Br. J. Pharmacol., 86, 663-670.
    • (1985) Br. J. Pharmacol. , vol.86 , pp. 663-670
    • Curtis, M.J.1    Macleod, B.A.2    Walker, M.J.3
  • 11
    • 0022495450 scopus 로고
    • The mechanism of action of the optical enantiomers of verapamil against ischaemia-induced arrhythmias in the conscious rat
    • CURTIS, M.J. & WALKER, M.J.A. (1986). The mechanism of action of the optical enantiomers of verapamil against ischaemia-induced arrhythmias in the conscious rat. Br. J. Pharmacol., 89, 137-147.
    • (1986) Br. J. Pharmacol. , vol.89 , pp. 137-147
    • Curtis, M.J.1    Walker, M.J.A.2
  • 12
    • 0014531918 scopus 로고
    • The relevance of beta adrenoceptor blockade of ouabain-induced cardiac arrhythmias
    • DOHADWALLA, A.N., FREEDBERG, A.S. & VAUGHAN WILLIAMS, E.M. (1969). The relevance of beta adrenoceptor blockade of ouabain-induced cardiac arrhythmias. Br. J. Pharmacol., 36, 257-267.
    • (1969) Br. J. Pharmacol. , vol.36 , pp. 257-267
    • Dohadwalla, A.N.1    Freedberg, A.S.2    Vaughan Williams, E.M.3
  • 13
    • 0024601509 scopus 로고
    • Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle
    • DELPON, E., VALENZUELA, C. & TAMARGO, J. (1989). Electrophysiological effects of E-3753, a new antiarrhythmic drug, in guinea-pig ventricular muscle. Br. J. Pharmacol., 96, 970-976.
    • (1989) Br. J. Pharmacol. , vol.96 , pp. 970-976
    • Delpon, E.1    Valenzuela, C.2    Tamargo, J.3
  • 14
    • 0013957422 scopus 로고
    • Un chapitre nouveau d'electro-cardiographie: Les variations progressives de l'amplitude de l'electrocardiogramme
    • DESSERTENNE, F., FABIATO, A. & COUMEL, P. (1966). Un chapitre nouveau d'electro-cardiographie: Les variations progressives de l'amplitude de l'electrocardiogramme. Actual Cardiol. Angeiol. Int., 15, 241-258.
    • (1966) Actual Cardiol. Angeiol. Int. , vol.15 , pp. 241-258
    • Dessertenne, F.1    Fabiato, A.2    Coumel, P.3
  • 15
    • 0023143187 scopus 로고
    • Antiarrhythmic agents and the modulated receptor hypothesis
    • HONDEGHEM, L. (1987). Antiarrhythmic agents and the modulated receptor hypothesis. Circulation, 75, 514-520.
    • (1987) Circulation , vol.75 , pp. 514-520
    • Hondeghem, L.1
  • 16
    • 0025886685 scopus 로고
    • Effects of zaprinast and rolipram on platelet aggregation and arrhythmias following myocardial ischaemia and reperfusion in anaesthetized rabbits
    • HOLBROOK, M. & COKER, S.J. (1991). Effects of zaprinast and rolipram on platelet aggregation and arrhythmias following myocardial ischaemia and reperfusion in anaesthetized rabbits. Br. J. Pharmacol., 103, 1973-1979.
    • (1991) Br. J. Pharmacol. , vol.103 , pp. 1973-1979
    • Holbrook, M.1    Coker, S.J.2
  • 17
    • 0021248092 scopus 로고
    • An investigation into the characteristics of reperfusion-induced arrhythmias in the anaesthetized rat and their susceptibility to antiarrhythmic agents
    • KANE, K.A., PARRATT, J.R. & WILLIAMS, F.M. (1984). An investigation into the characteristics of reperfusion-induced arrhythmias in the anaesthetized rat and their susceptibility to antiarrhythmic agents. Br. J. Pharmacol., 82, 349-357.
    • (1984) Br. J. Pharmacol. , vol.82 , pp. 349-357
    • Kane, K.A.1    Parratt, J.R.2    Williams, F.M.3
  • 18
    • 4644231793 scopus 로고    scopus 로고
    • Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: Importance of the decreased repolarisation reserve in the development of proarrhythmic risk
    • LENGYEL, C., DÉZSI, L., BILICZKI, P., HORVATH, C., VIRÁG, L., IOST, N., NÉMETH, M., TÁLOSI, L., PAPP, J.G. & VARRO, A. (2004). Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk. Br. J. Pharmacol., 143, 152-158.
    • (2004) Br. J. Pharmacol. , vol.143 , pp. 152-158
    • Lengyel, C.1    Dézsi, L.2    Biliczki, P.3    Horvath, C.4    Virág, L.5    Iost, N.6    Németh, M.7    Tálosi, L.8    Papp, J.G.9    Varro, A.10
  • 19
    • 0028477783 scopus 로고
    • Stories about the origin of quinquina & quinidine
    • LEVY, S. & AZOULAY, S. (1994). Stories about the origin of quinquina & quinidine. J. Cardiovasc. Electrophysiol., 5, 635-636.
    • (1994) J. Cardiovasc. Electrophysiol. , vol.5 , pp. 635-636
    • Levy, S.1    Azoulay, S.2
  • 21
    • 0038497465 scopus 로고    scopus 로고
    • Blockade of HERG potassium currents by fluvoxamine: Incomplete attenuation by S6 mutations at F656 or Y652
    • MILNES, J.T., CROCIANI, O., ARCANGELI, A., HANCOX, J.C. & WITCHEL, H.J. (2003). Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652. Br. J. Pharmacol., 139, 887-898.
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 887-898
    • Milnes, J.T.1    Crociani, O.2    Arcangeli, A.3    Hancox, J.C.4    Witchel, H.J.5
  • 22
    • 1842610702 scopus 로고    scopus 로고
    • Sildenafil (Viagra) reduces arrhythmia severity during ischaemia 24 h after oral administration in dogs
    • NAGY, O., HAJNAL, A., PARRATT, J.R. & VÉGH, A. (2004). Sildenafil (Viagra) reduces arrhythmia severity during ischaemia 24 h after oral administration in dogs. Br. J. Pharmacol., 141, 549-551.
    • (2004) Br. J. Pharmacol. , vol.141 , pp. 549-551
    • Nagy, O.1    Hajnal, A.2    Parratt, J.R.3    Végh, A.4
  • 23
    • 0024386085 scopus 로고
    • Mechanisms underlying the antiarrhythmic properties of beta-adrenoceptor blockade against ischaemia-induced arrhythmias in acutely prepared rats
    • PALETTA, M.J., ABRAHAM, S., BEATCH, G.N. & WALKER, M.J.A. (1989). Mechanisms underlying the antiarrhythmic properties of beta-adrenoceptor blockade against ischaemia-induced arrhythmias in acutely prepared rats. Br. J. Pharmacol., 98, 87-94.
    • (1989) Br. J. Pharmacol. , vol.98 , pp. 87-94
    • Paletta, M.J.1    Abraham, S.2    Beatch, G.N.3    Walker, M.J.A.4
  • 24
    • 0027339835 scopus 로고
    • Selective IK blockade as an antiarrhythmic mechanism: Effects of UK66,914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts
    • REES, S.A. & CURTIS, M.J. (1993). Selective IK blockade as an antiarrhythmic mechanism: effects of UK66,914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts. Br. J. Pharmacol., 108, 139-145.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 139-145
    • Rees, S.A.1    Curtis, M.J.2
  • 25
    • 0141763530 scopus 로고    scopus 로고
    • Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats
    • SARRAF, G., BARRETT, T.D. & WALKER, M.J.A. (2003). Tedisamil and lidocaine enhance each other's antiarrhythmic activity against ischaemia-induced arrhythmias in rats. Br. J. Pharmacol., 139, 1389-1398.
    • (2003) Br. J. Pharmacol. , vol.139 , pp. 1389-1398
    • Sarraf, G.1    Barrett, T.D.2    Walker, M.J.A.3
  • 26
    • 78651117091 scopus 로고
    • A comparison of the antifibrillatory actions and effects on intracellular cardiac potentials of pronethalol, disopyramide and quinidine
    • SEKIYA, A. & VAUGHAN WILLIAMS, E.M. (1963). A comparison of the antifibrillatory actions and effects on intracellular cardiac potentials of pronethalol, disopyramide and quinidine. Br. J. Pharmacol., 21, 473-481.
    • (1963) Br. J. Pharmacol. , vol.21 , pp. 473-481
    • Sekiya, A.1    Vaughan Williams, E.M.2
  • 27
    • 0014769207 scopus 로고
    • Local anaesthetic and anti-arrhythmic actions of alprenolol relative to its effect on intracellular potentials and other properties of isolated cardiac muscle
    • SINGH, B.N. & VAUGHAN WILLIAMS, E.M. (1970a). Local anaesthetic and anti-arrhythmic actions of alprenolol relative to its effect on intracellular potentials and other properties of isolated cardiac muscle. Br. J. Pharmacol., 38, 749-757.
    • (1970) Br. J. Pharmacol. , vol.38 , pp. 749-757
    • Singh, B.N.1    Vaughan Williams, E.M.2
  • 28
    • 0014828868 scopus 로고
    • A third class of anti-arrhythmic action. Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscles, of MJ 1999 and AH 3474
    • SINGH, B.N. & VAUGHAN WILLIAMS, E.M. (1970b). A third class of anti-arrhythmic action. Effects on atrial and ventricular intracellular potentials, and other pharmacological actions on cardiac muscles, of MJ 1999 and AH 3474. Br. J. Pharmacol., 39, 675-687.
    • (1970) Br. J. Pharmacol. , vol.39 , pp. 675-687
    • Singh, B.N.1    Vaughan Williams, E.M.2
  • 29
    • 0032853542 scopus 로고    scopus 로고
    • Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline
    • TESCHEMACHER, A.G., SEWARD, E.P., HANCOX, J.C. & WITCHEL, H.J. (1999). Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline. Br. J. Pharmacol., 128, 479-485.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 479-485
    • Teschemacher, A.G.1    Seward, E.P.2    Hancox, J.C.3    Witchel, H.J.4
  • 31
    • 0026486145 scopus 로고
    • Classifying antiarrhythmic actions: By facts or speculation
    • VAUGHAN WILLIAMS, E.M. (1992). Classifying antiarrhythmic actions: by facts or speculation. J. Clin. Pharmacol., 32, 964-977.
    • (1992) J. Clin. Pharmacol. , vol.32 , pp. 964-977
    • Vaughan Williams, E.M.1
  • 32
    • 7144255763 scopus 로고
    • A comparison of tests for antifibrillatory actions
    • VAUGHAN WILLIAMS, E.M. & SZEKERES, L. (1961). A comparison of tests for antifibrillatory actions. Br. J. Pharmacol., 17, 424-432.
    • (1961) Br. J. Pharmacol. , vol.17 , pp. 424-432
    • Vaughan Williams, E.M.1    Szekeres, L.2
  • 34
    • 0025947046 scopus 로고
    • Local intracoronary infusions of bradykinin profoundly reduce the severity of ischaemia-induced arrhythmias in anaesthetized dogs
    • VEGH, A., SZEKERES, L. & PARRATT, J.R. (1991). Local intracoronary infusions of bradykinin profoundly reduce the severity of ischaemia-induced arrhythmias in anaesthetized dogs. Br. J. Pharmacol., 104, 294-295.
    • (1991) Br. J. Pharmacol. , vol.104 , pp. 294-295
    • Vegh, A.1    Szekeres, L.2    Parratt, J.R.3
  • 35
    • 0027236998 scopus 로고
    • Prevention by an inhibitor of the L-arginine-nitric oxide pathway of the antiarrhythmic effects of bradykinin in anaesthetized dogs
    • VEGH, A., PAPP, J.G., SZEKERES, L. & PARRATT, J.R. (1993). Prevention by an inhibitor of the L-arginine-nitric oxide pathway of the antiarrhythmic effects of bradykinin in anaesthetized dogs. Br. J. Pharmacol., 110, 18-19.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 18-19
    • Vegh, A.1    Papp, J.G.2    Szekeres, L.3    Parratt, J.R.4
  • 36
    • 0000841151 scopus 로고
    • Cinchona derivatives in the treatment of heart disorders
    • WENCKEBACH, K.F. (1923). Cinchona derivatives in the treatment of heart disorders. J. Am. Med. Assoc., 81, 472-474.
    • (1923) J. Am. Med. Assoc. , vol.81 , pp. 472-474
    • Wenckebach, K.F.1
  • 37
    • 0027471071 scopus 로고
    • Effects of hyperkalaemia on the depression of maximum rate of depolarization by class I antiarrhythmic agents in guinea-pig myocardium
    • WYSE, K.R., YE, V. & CAMPBELL, T.J. (1993). Effects of hyperkalaemia on the depression of maximum rate of depolarization by class I antiarrhythmic agents in guinea-pig myocardium. Br. J. Pharmacol., 108, 255-261.
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 255-261
    • Wyse, K.R.1    Ye, V.2    Campbell, T.J.3


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