The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels

Journal of Controlled Release

Volumn 80, Issue 1-3, 2002, Pages 87-100

  Martin, Lee ^a   Wilson, Clive G ^a   Koosha, Fariba ^b   Tetley, Laurence ^c   Gray, Alexander I ^a   Senel, Sevda ^d   Uchegbu, Ijeoma F ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Controlled release; Drug delivery; Fluorescein isothiocyanate dextran (FITC dextran); Hydrogel; Macromolecules; Palmitoyl glycol chitosan

Indexed keywords

ALPHA TOCOPHEROL; CARBOMER; CHITOSAN; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GELUCIRE; PALMITOYLGLYCOL; UNCLASSIFIED DRUG;

ADHESION; ARTICLE; CONTROLLED DRUG RELEASE; CROSS LINKING; DISPERSION; DRUG DELIVERY SYSTEM; DRUG SYNTHESIS; EROSION; HYDRATION; HYDROGEL; HYDROPHOBICITY; MACROMOLECULE; MODEL; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

CHITIN; CHITOSAN; HYDROGELS; HYDROPHOBICITY;

EID: 0037161322     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(02)00005-6     Document Type: Article

References (41)

1. Permeability of vitamin B12 in chitosan membranes - Effect of cross-linking with poly(vinyl alcohol) on permeability
2. pH sensitivity of hydrogels based on complex forming chitosan: Polyether interpenetrating network
3. Structural-changes of pH-sensitive chitosan polyether hydrogels in different pH solution
4. pH sensitivity and ion sensitivity of hydrogels based on complex forming chitosan/silk fibroin interpenetrating polymer network
5. Preparation and characterization of freeze-dried chitosan-poly(ethylene oxide) hydrogels for site-specific antibiotic delivery in the stomach
6. Synthesis and properties of poly(ethylene glycol) macromer/beta-chitosan hydrogels
7. Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery
8. Reductive amination using poly(ethylene glycol) acetaldehyde hydrate generated in situ: Applications to chitosan and lysozyme
9. Sclerox-chitosan co-gels: Effects of charge density on swelling of gels in ionic aqueous solution and in poor solvents, and on the rehydration of dried gels
10. 13C CP-MAS NMR characterization of a new chitosan-based polymeric network
11. Interpolymer complexes of chitosan and polymethacrylic acid derivatives of salicylic acid: Preparation, characterization and modification by thermal treatment
12. Synthesis and characteristics of interpenetrating polymer network hydrogel composed of chitosan and poly(acrylic acid)
13. Studies on chitosan and poly(acrylic acid) interpolymer complex, 1. Preparation, structure, pH sensitivity and salt sensitivity of complex-forming poly(acrylic acid): Chitosan semi-interpenetrating polymer network
14. Swelling properties and mechanical characterization of a semi-interpenetrating chitosan/polyethylene oxide network - Comparison with a chitosan reference gel
15. Hydrocolloids and gels of chitosan as drug carriers
16. Chitosan-EDTA conjugate: A novel polymer for topical gels
17. A non-covalently cross-linked chitosan based hydrogel
18. Synthesis and characterization of pH-sensitive hydrogels based on chitosan and D,L-lactic acid
19. Thermo- and pH-responsive behaviours of graft copolymer and blend based on chitosan and N-isopropyl acrylamide
20. Chitosan-carboxymethylcellulose hydrogels as supports for cell immobilization
21. Effect of chitosan and dextran on the properties of poly(vinyl alcohol) hydrogels
22. Preparation and properties of hydrogels based on hemicellulose
23. Physically crosslinked dextran hydrogels by stereocomplex formation of lactic acid oligomers: Degradation and protein release behavior
24. Polymeric chitosan-based vesicles for drug delivery
25. Controls on polymer molecular weight may be used to control the size of palmitoyl glycol chitosan polymeric vesicles
26. Oral cavity as a site for bioadhesive drug-delivery
27. Polycation induced enhancement of epithelial paracellulal permeability is independent of tight junctional characteristics
28. Effects of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)
29. Chitosan as a nasal delivery system: Evaluation of insulin absorption enhancement and effect of nasal membrane integrity using rat models
30. Biodegradable hydrogels in drug delivery
31. Chitosan films and hydrogels of chlorhexidine gluconate for oral mucosal delivery
32. Diffusional properties of chitosan hydrogel membranes
33. Buccal delivery of fluorescein isothiocyanate-dextran 4400 and the peptide drug buserelin with glycodeoxycholate as an absorption enhancer in pigs
34. Characterization of thermosensitive chitosan gels for the sustained delivery of drugs
35. Surface states of PVA/chitosan blended hydrogels
36. Study of biodegradation behavior of chitosan-xanthan microspheres in simulated physiological media
37. pH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery
38. In vivo evaluation of hydrophilic and hydrophobic mucoadhesive semi-solid formulations containing sucralfate and lidocaine for intraoral use
39. In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers
40. Hydrogel delivery systems for vaginal and oral applications
41. In-vitro assessment of bioadhesion for periodontal and buccal drug-delivery