Effects of a new neuroprotective agent KR-31378 on liver cytochrome P450s in male sprague dawley rats

Archives of Pharmacal Research

Volumn 26, Issue 10, 2003, Pages 800-804

  Tae, Cheon Jeong ^a   Kim, Ji Young ^a   Hye, Young Ji ^b   Dong, Ha Lee ^c   Kim, Sun Ok ^c   Lim, Hong ^c   Sung, Eun Yoo ^d   Hye, Suk Lee ^b  

^a Yeungnam University   (South Korea)

^b Wonkwang University   (South Korea)

^c Dongbu Hannong Chemical Co   (South Korea)

^d Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Cytochrome P450; In vivo; Induction; KR 31378; Rat

Indexed keywords

CYP3A PROTEIN, HUMAN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 2B1; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; GUANIDINE DERIVATIVE; N DEMETHYLASE; N'' CYANO N (6 AMINO 3,4 DIHYDRO 3 HYDROXY 2 METHYL 2 DIMETHOXYMETHYL 2H BENZOPYRAN 4 YL) N' BENZYLGUANIDINE; N''-CYANO-N-(6-AMINO-3,4-DIHYDRO-3-HYDROXY-2-METHYL-2-DIMETHOXYMETHYL-2H-BENZOPYRAN-4-YL)-N'-BENZYLGUANIDINE; NEUROPROTECTIVE AGENT; PYRAN DERIVATIVE; UNSPECIFIC MONOOXYGENASE;

ANIMAL; ARTICLE; BIOSYNTHESIS; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG EFFECT; ENZYMOLOGY; LIVER MICROSOME; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; SPRAGUE DAWLEY RAT; SYNTHESIS; TIME; WESTERN BLOTTING;

ADMINISTRATION, ORAL; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BLOTTING, WESTERN; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP2B1; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GUANIDINES; MALE; MICROSOMES, LIVER; NEUROPROTECTIVE AGENTS; OXIDOREDUCTASES, N-DEMETHYLATING; PYRANS; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 30444433948     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/bf02980023     Document Type: Article

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