메뉴 건너뛰기




Volumn 49, Issue 5, 2004, Pages 828-832

TGF-β and p53 staining in CT-guided and endoscopic ultrasound fine-needle aspirates of pancreatic adenocarcinoma

Author keywords

endoscopic ultrasound; p53; pancreatic cancer; transforming growth factor ; tumor markers

Indexed keywords

PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA; TUMOR MARKER;

EID: 3042850196     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:DDAS.0000030095.71501.04     Document Type: Article
Times cited : (15)

References (33)
  • 2
    • 0031595728 scopus 로고    scopus 로고
    • Analysis of p53, p21 WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta protein expression predicts longer survival
    • Coppola D, Lu L, Fruehauf JP, Kyshtoobayeva A, Karl RC, Nicosia SV, Yeatman TS: Analysis of p53, p21 WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta protein expression predicts longer survival. Am J Clin Pathol 110:16-23, 1998
    • (1998) Am J Clin Pathol , vol.110 , pp. 16-23
    • Coppola, D.1    Lu, L.2    Fruehauf, J.P.3    Kyshtoobayeva, A.4    Karl, R.C.5    Nicosia, S.V.6    Yeatman, T.S.7
  • 5
    • 0032979931 scopus 로고    scopus 로고
    • Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic and carcinomatous lesions of the pancreas: Evidence for multistep carcinogenesis
    • Apple SK, Hecht JR, Lewin DN, Jahromi SA, Grody WW, Nieberg RK. Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic and carcinomatous lesions of the pancreas: Evidence for multistep carcinogenesis. Hum Pathol 30:123-129, 1999
    • (1999) Hum Pathol , vol.30 , pp. 123-129
    • Apple, S.K.1    Hecht, J.R.2    Lewin, D.N.3    Jahromi, S.A.4    Grody, W.W.5    Nieberg, R.K.6
  • 7
    • 0035234009 scopus 로고    scopus 로고
    • Characterization of mutations of the K-ras, p53, p16 and SMAD4 genes in 15 human pancreatic cancer cell lines
    • Sun C, Yamato T, Furukawa T, Ohnishi Y, Kijima H, Horii A: Characterization of mutations of the K-ras, p53, p16 and SMAD4 genes in 15 human pancreatic cancer cell lines. Oncol Rep 8:89-92, 2001
    • (2001) Oncol Rep , vol.8 , pp. 89-92
    • Sun, C.1    Yamato, T.2    Furukawa, T.3    Ohnishi, Y.4    Kijima, H.5    Horii, A.6
  • 8
    • 0035085625 scopus 로고    scopus 로고
    • Expression of Bcl-2 and p53 protein in resectable invasive ductal carcinoma of the pancreas: Effects on clinical outcome and efficiency of adjuvant chemotherapy
    • Nio Y, Dong M, Iguchi C, Yamasawa K, Toga T, Itakura M, Tamura K. Expression of Bcl-2 and p53 protein in resectable invasive ductal carcinoma of the pancreas: Effects on clinical outcome and efficiency of adjuvant chemotherapy. J Surg Oncol 76:188-196, 2001
    • (2001) J Surg Oncol , vol.76 , pp. 188-196
    • Nio, Y.1    Dong, M.2    Iguchi, C.3    Yamasawa, K.4    Toga, T.5    Itakura, M.6    Tamura, K.7
  • 9
    • 0034693635 scopus 로고    scopus 로고
    • K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2, and erbB-3 in resected pancreatic ductal adenocarcinoma
    • Kawesha A, Ghaneh P, Andren-Sandberg A, Ograed D, Skar R, Dawiskiba S, Evans JD, Campbell F, Lemione N, Neoptolemos JP: K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2, and erbB-3 in resected pancreatic ductal adenocarcinoma. Int J Cancer 89:469-474, 2000
    • (2000) Int J Cancer , vol.89 , pp. 469-474
    • Kawesha, A.1    Ghaneh, P.2    Andren-Sandberg, A.3    Ograed, D.4    Skar, R.5    Dawiskiba, S.6    Evans, J.D.7    Campbell, F.8    Lemione, N.9    Neoptolemos, J.P.10
  • 10
    • 0033807873 scopus 로고    scopus 로고
    • p53 protein expression in intraductal papillary mucinous tumors (IPMT) of the pancreas as an indicator of tumor malignancy
    • Kawahira H, Kobatashi S, Kaneko K, Asano T, Ochiai T: p53 protein expression in intraductal papillary mucinous tumors (IPMT) of the pancreas as an indicator of tumor malignancy. Hepatogastroenterology 47:973-977, 2000
    • (2000) Hepatogastroenterology , vol.47 , pp. 973-977
    • Kawahira, H.1    Kobatashi, S.2    Kaneko, K.3    Asano, T.4    Ochiai, T.5
  • 11
    • 0033190986 scopus 로고    scopus 로고
    • Genetic background determines the response to adenovirus-mediated wild type p53 expression in pancreatic tumor cells
    • Cascallo M, Mercade E, Capella G, Lluis F, Filial C, Gomez-Foix AM, Mazo A: Genetic background determines the response to adenovirus-mediated wild type p53 expression in pancreatic tumor cells. Cancer Gene Ther 6:428-436, 1999
    • (1999) Cancer Gene Ther , vol.6 , pp. 428-436
    • Cascallo, M.1    Mercade, E.2    Capella, G.3    Lluis, F.4    Filial, C.5    Gomez-Foix, A.M.6    Mazo, A.7
  • 12
  • 13
    • 0032792828 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells
    • Kusumoto M,Ogawa T, Mizumoto K, Ueno H, Niiyama H, Sato N, Nakamura M, Tanaka M: Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells. Clin Cancer Res 5:2140-2147, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 2140-2147
    • Kusumoto, M.1    Ogawa, T.2    Mizumoto, K.3    Ueno, H.4    Niiyama, H.5    Sato, N.6    Nakamura, M.7    Tanaka, M.8
  • 14
    • 0037127220 scopus 로고    scopus 로고
    • Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2
    • Ahmed MM, Alcock RA, Chendil D, Dey S, Das A, Venkatasubbarao K, Mohiuddin M, Sun L, Strodel WE, Freeman JW: Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2. J Biol Chem 277:2234-2246, 2002
    • (2002) J Biol Chem , vol.277 , pp. 2234-2246
    • Ahmed, M.M.1    Alcock, R.A.2    Chendil, D.3    Dey, S.4    Das, A.5    Venkatasubbarao, K.6    Mohiuddin, M.7    Sun, L.8    Strodel, W.E.9    Freeman, J.W.10
  • 15
    • 0035067212 scopus 로고    scopus 로고
    • Treatment based on a combination of CYP2B1/cyclophosphamide system and p53 delivery enhances tumour regression in human pancreatic cancer
    • Mercade E, Cascallo M, Carrio M, Calbo J, Gomez-Trevino A, Fillat C, Gomez-Foix AM, Mazo A: Treatment based on a combination of CYP2B1/ cyclophosphamide system and p53 delivery enhances tumour regression in human pancreatic cancer. Ann Oncol 12:379-388, 2001
    • (2001) Ann Oncol , vol.12 , pp. 379-388
    • Mercade, E.1    Cascallo, M.2    Carrio, M.3    Calbo, J.4    Gomez-Trevino, A.5    Fillat, C.6    Gomez-Foix, A.M.7    Mazo, A.8
  • 16
    • 0034102707 scopus 로고    scopus 로고
    • Ki-ras point mutation and p53 expression in human pancreatic cancer: A comparative study among Chinese, Japanese and Western patients
    • Dong M, Nio Y, Tamura K, Song MM, Guo KJ, Guo RX, Dong YT: Ki-ras point mutation and p53 expression in human pancreatic cancer: A comparative study among Chinese, Japanese and Western patients. Cancer Epidemiol Biomark Prev 9:273-284, 2000
    • (2000) Cancer Epidemiol Biomark Prev , vol.9 , pp. 273-284
    • Dong, M.1    Nio, Y.2    Tamura, K.3    Song, M.M.4    Guo, K.J.5    Guo, R.X.6    Dong, Y.T.7
  • 17
    • 0032901753 scopus 로고    scopus 로고
    • Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to diagnosis of patients with pancreatic cancer: Comparison with K-ras mutation
    • Yamaguchi Y, Watanabe H, Yrdiran S, Ohtsubo K, Motoo Y, Okai T, Sawabu N: Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to diagnosis of patients with pancreatic cancer: Comparison with K-ras mutation. Clin Cancer Res 5:1147-1153, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 1147-1153
    • Yamaguchi, Y.1    Watanabe, H.2    Yrdiran, S.3    Ohtsubo, K.4    Motoo, Y.5    Okai, T.6    Sawabu, N.7
  • 18
    • 0033869440 scopus 로고    scopus 로고
    • Ki-ras codon 12 point and p53 mutations: A molecular examination of the main tumor, liver, portal vein, peripheral arterial blood and para-aortic lymph node in pancreatic cancer
    • Yamaguchi K, Chijiiwa K, Torato N, Kinoshita M, Tanaka M: Ki-ras codon 12 point and p53 mutations: A molecular examination of the main tumor, liver, portal vein, peripheral arterial blood and para-aortic lymph node in pancreatic cancer. Am J Gastroenterol 95:1939-1945, 2000
    • (2000) Am J Gastroenterol , vol.95 , pp. 1939-1945
    • Yamaguchi, K.1    Chijiiwa, K.2    Torato, N.3    Kinoshita, M.4    Tanaka, M.5
  • 19
    • 0033508689 scopus 로고    scopus 로고
    • An immunohistochemical study of the expression of bcl-2 and p53 oncoproteins in pancreatic intraepithelial neoplastic and pancreatic cancer
    • Tomaszewska R, Karcz D, Stachura J: An immunohistochemical study of the expression of bcl-2 and p53 oncoproteins in pancreatic intraepithelial neoplastic and pancreatic cancer. Int J Pancreatol 26:163-171, 1999
    • (1999) Int J Pancreatol , vol.26 , pp. 163-171
    • Tomaszewska, R.1    Karcz, D.2    Stachura, J.3
  • 22
    • 0033497531 scopus 로고    scopus 로고
    • Sequential accumulation of K-ras mutation and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy
    • Jimenez RE, Warshaw AL, Zgraggen K, Hartwig W, Taylor DZ, Compton CC, Fernandez-del Castillo: Sequential accumulation of K-ras mutation and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy. Ann Surg 230:501-509, 1999
    • (1999) Ann Surg , vol.230 , pp. 501-509
    • Jimenez, R.E.1    Warshaw, A.L.2    Zgraggen, K.3    Hartwig, W.4    Taylor, D.Z.5    Compton, C.C.6    Fernandez-del Castillo7
  • 23
    • 0037128687 scopus 로고    scopus 로고
    • Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma
    • Sarela AI, Verbeke CS, Ramsdale J, Davies CL, Markham AF, Guillou PJ: Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br J Cancer 86:886-892, 2002
    • (2002) Br J Cancer , vol.86 , pp. 886-892
    • Sarela, A.I.1    Verbeke, C.S.2    Ramsdale, J.3    Davies, C.L.4    Markham, A.F.5    Guillou, P.J.6
  • 24
    • 0032767855 scopus 로고    scopus 로고
    • Molecular aspects of pancreatic cancer and future perspectives
    • Friess H, Kleeff J, Korc M, Buchler MW: Molecular aspects of pancreatic cancer and future perspectives. Dig Surg 16:281-290, 1999
    • (1999) Dig Surg , vol.16 , pp. 281-290
    • Friess, H.1    Kleeff, J.2    Korc, M.3    Buchler, M.W.4
  • 25
    • 0027131252 scopus 로고
    • Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival
    • Friess H, Yamanaka Y, Buchler M, Ebert M, Beger HG, Gold LI, Korc M: Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 105:1846-1856, 1993
    • (1993) Gastroenterology , vol.105 , pp. 1846-1856
    • Friess, H.1    Yamanaka, Y.2    Buchler, M.3    Ebert, M.4    Beger, H.G.5    Gold, L.I.6    Korc, M.7
  • 26
    • 0034648528 scopus 로고    scopus 로고
    • TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation
    • Giehl K, Seidel B, Gierschik P, Adler G, Menke A: TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation. Oncoge 19:4531-4541, 2000
    • (2000) Oncoge , vol.19 , pp. 4531-4541
    • Giehl, K.1    Seidel, B.2    Gierschik, P.3    Adler, G.4    Menke, A.5
  • 27
    • 0033623872 scopus 로고    scopus 로고
    • Disruption of TGFbeta signaling pathways in human pancreatic cancer cells
    • Simeone DM, Pham T, Logsdon CD: Disruption of TGFbeta signaling pathways in human pancreatic cancer cells. Ann Surg 232:73-80, 2000
    • (2000) Ann Surg , vol.232 , pp. 73-80
    • Simeone, D.M.1    Pham, T.2    Logsdon, C.D.3
  • 30
    • 0032711157 scopus 로고    scopus 로고
    • Enhanced expression of the type II transforming growth factor b receptor is associated with decreased survival in human pancreatic cancer
    • Wagner M, Kleeff J, Friess H, Buchler M, Korc M: Enhanced expression of the type II transforming growth factor b receptor is associated with decreased survival in human pancreatic cancer. Pancreas 19:370-376, 1999
    • (1999) Pancreas , vol.19 , pp. 370-376
    • Wagner, M.1    Kleeff, J.2    Friess, H.3    Buchler, M.4    Korc, M.5
  • 31
    • 0030715078 scopus 로고    scopus 로고
    • Clinical utility of endoscopie ultrasound-guided fine needle aspiration
    • Erickson RA, Sayage-Rabie L, Avots-Avotins A: Clinical utility of endoscopie ultrasound-guided fine needle aspiration. Acta Cytol 41:1647-1653, 1997
    • (1997) Acta Cytol , vol.41 , pp. 1647-1653
    • Erickson, R.A.1    Sayage-Rabie, L.2    Avots-Avotins, A.3
  • 32
    • 0033980883 scopus 로고    scopus 로고
    • Factors predicting the number of EUS-guided fine needle passes for diagnosis of pancreatic malignancies
    • Erickson RA, Sayage-Rabie L, Beisner RS: Factors predicting the number of EUS-guided fine needle passes for diagnosis of pancreatic malignancies. Gastrointest Endosc 51:184-190, 2000
    • (2000) Gastrointest Endosc , vol.51 , pp. 184-190
    • Erickson, R.A.1    Sayage-Rabie, L.2    Beisner, R.S.3
  • 33
    • 0033998601 scopus 로고    scopus 로고
    • Transforming growth-factor beta1 acts as a potent inhibitor of complement C3 biosynthesis in human pancreatic cancer cell lines
    • Andoh A, Shimada M, Takaya H, Hata K, Fujiyama Y, Bamba T: Transforming growth-factor beta1 acts as a potent inhibitor of complement C3 biosynthesis in human pancreatic cancer cell lines. Pancreas 20:138-145, 2000
    • (2000) Pancreas , vol.20 , pp. 138-145
    • Andoh, A.1    Shimada, M.2    Takaya, H.3    Hata, K.4    Fujiyama, Y.5    Bamba, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.