-
1
-
-
0031963294
-
Cancer statistics, 1998
-
Landis SH, Murray T, Bolden S, Wingo PA: Cancer statistics, 1998. CA Cancer J Clin 48:6-29, 1998
-
(1998)
CA Cancer J Clin
, vol.48
, pp. 6-29
-
-
Landis, S.H.1
Murray, T.2
Bolden, S.3
Wingo, P.A.4
-
2
-
-
0031595728
-
Analysis of p53, p21 WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta protein expression predicts longer survival
-
Coppola D, Lu L, Fruehauf JP, Kyshtoobayeva A, Karl RC, Nicosia SV, Yeatman TS: Analysis of p53, p21 WAF1, and TGF-beta1 in human ductal adenocarcinoma of the pancreas: TGF-beta protein expression predicts longer survival. Am J Clin Pathol 110:16-23, 1998
-
(1998)
Am J Clin Pathol
, vol.110
, pp. 16-23
-
-
Coppola, D.1
Lu, L.2
Fruehauf, J.P.3
Kyshtoobayeva, A.4
Karl, R.C.5
Nicosia, S.V.6
Yeatman, T.S.7
-
3
-
-
0033050187
-
p53 overexpression in lymph node metastases predicts clinical outcome in ductal pancreatic cancer
-
Campani D, Boggi U, Cecchetti D, Esposito I, Ceccarelli F, D'Antonio L, De Negri F, Mosca F, Bevilacqua G, Fornaciara G: p53 overexpression in lymph node metastases predicts clinical outcome in ductal pancreatic cancer. Pancreas 19:26-32, 1999
-
(1999)
Pancreas
, vol.19
, pp. 26-32
-
-
Campani, D.1
Boggi, U.2
Cecchetti, D.3
Esposito, I.4
Ceccarelli, F.5
D'Antonio, L.6
De Negri, F.7
Mosca, F.8
Bevilacqua, G.9
Fornaciara, G.10
-
4
-
-
0033122710
-
Prognostic factors in resectable pancreatic cancer: p53 and bcl-2
-
Bold RJ, Hess KR, Pearson AS, Grau AM, Sinicrope FA, Jennings M, McConkey DJ, Bucana CD, Clearly ICR, Hallin PA, Chiao PJ, Abbruzzese JL, Evans DB: Prognostic factors in resectable pancreatic cancer: p53 and bcl-2. J Gastrointest Surg 3:263-277, 1999
-
(1999)
J Gastrointest Surg
, vol.3
, pp. 263-277
-
-
Bold, R.J.1
Hess, K.R.2
Pearson, A.S.3
Grau, A.M.4
Sinicrope, F.A.5
Jennings, M.6
McConkey, D.J.7
Bucana, C.D.8
Clearly, I.C.R.9
Hallin, P.A.10
Chiao, P.J.11
Abbruzzese, J.L.12
Evans, D.B.13
-
5
-
-
0032979931
-
Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic and carcinomatous lesions of the pancreas: Evidence for multistep carcinogenesis
-
Apple SK, Hecht JR, Lewin DN, Jahromi SA, Grody WW, Nieberg RK. Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic and carcinomatous lesions of the pancreas: Evidence for multistep carcinogenesis. Hum Pathol 30:123-129, 1999
-
(1999)
Hum Pathol
, vol.30
, pp. 123-129
-
-
Apple, S.K.1
Hecht, J.R.2
Lewin, D.N.3
Jahromi, S.A.4
Grody, W.W.5
Nieberg, R.K.6
-
6
-
-
0035207991
-
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4
-
Moore PS, Sipos B, Orlandini S, Sorio C, Real FX, Lemoine NR, Gress T, Bassi C, Kloppel G, Kalthoff H, Ungefroren H, Lohr M, Scarpa A: Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4. Virchows Arch 439:798-802, 2001
-
(2001)
Virchows Arch
, vol.439
, pp. 798-802
-
-
Moore, P.S.1
Sipos, B.2
Orlandini, S.3
Sorio, C.4
Real, F.X.5
Lemoine, N.R.6
Gress, T.7
Bassi, C.8
Kloppel, G.9
Kalthoff, H.10
Ungefroren, H.11
Lohr, M.12
Scarpa, A.13
-
7
-
-
0035234009
-
Characterization of mutations of the K-ras, p53, p16 and SMAD4 genes in 15 human pancreatic cancer cell lines
-
Sun C, Yamato T, Furukawa T, Ohnishi Y, Kijima H, Horii A: Characterization of mutations of the K-ras, p53, p16 and SMAD4 genes in 15 human pancreatic cancer cell lines. Oncol Rep 8:89-92, 2001
-
(2001)
Oncol Rep
, vol.8
, pp. 89-92
-
-
Sun, C.1
Yamato, T.2
Furukawa, T.3
Ohnishi, Y.4
Kijima, H.5
Horii, A.6
-
8
-
-
0035085625
-
Expression of Bcl-2 and p53 protein in resectable invasive ductal carcinoma of the pancreas: Effects on clinical outcome and efficiency of adjuvant chemotherapy
-
Nio Y, Dong M, Iguchi C, Yamasawa K, Toga T, Itakura M, Tamura K. Expression of Bcl-2 and p53 protein in resectable invasive ductal carcinoma of the pancreas: Effects on clinical outcome and efficiency of adjuvant chemotherapy. J Surg Oncol 76:188-196, 2001
-
(2001)
J Surg Oncol
, vol.76
, pp. 188-196
-
-
Nio, Y.1
Dong, M.2
Iguchi, C.3
Yamasawa, K.4
Toga, T.5
Itakura, M.6
Tamura, K.7
-
9
-
-
0034693635
-
K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2, and erbB-3 in resected pancreatic ductal adenocarcinoma
-
Kawesha A, Ghaneh P, Andren-Sandberg A, Ograed D, Skar R, Dawiskiba S, Evans JD, Campbell F, Lemione N, Neoptolemos JP: K-ras oncogene subtype mutations are associated with survival but not expression of p53, p16(INK4A), p21(WAF-1), cyclin D1, erbB-2, and erbB-3 in resected pancreatic ductal adenocarcinoma. Int J Cancer 89:469-474, 2000
-
(2000)
Int J Cancer
, vol.89
, pp. 469-474
-
-
Kawesha, A.1
Ghaneh, P.2
Andren-Sandberg, A.3
Ograed, D.4
Skar, R.5
Dawiskiba, S.6
Evans, J.D.7
Campbell, F.8
Lemione, N.9
Neoptolemos, J.P.10
-
10
-
-
0033807873
-
p53 protein expression in intraductal papillary mucinous tumors (IPMT) of the pancreas as an indicator of tumor malignancy
-
Kawahira H, Kobatashi S, Kaneko K, Asano T, Ochiai T: p53 protein expression in intraductal papillary mucinous tumors (IPMT) of the pancreas as an indicator of tumor malignancy. Hepatogastroenterology 47:973-977, 2000
-
(2000)
Hepatogastroenterology
, vol.47
, pp. 973-977
-
-
Kawahira, H.1
Kobatashi, S.2
Kaneko, K.3
Asano, T.4
Ochiai, T.5
-
11
-
-
0033190986
-
Genetic background determines the response to adenovirus-mediated wild type p53 expression in pancreatic tumor cells
-
Cascallo M, Mercade E, Capella G, Lluis F, Filial C, Gomez-Foix AM, Mazo A: Genetic background determines the response to adenovirus-mediated wild type p53 expression in pancreatic tumor cells. Cancer Gene Ther 6:428-436, 1999
-
(1999)
Cancer Gene Ther
, vol.6
, pp. 428-436
-
-
Cascallo, M.1
Mercade, E.2
Capella, G.3
Lluis, F.4
Filial, C.5
Gomez-Foix, A.M.6
Mazo, A.7
-
12
-
-
0035114253
-
Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo
-
Ghaneh P, Greenhalf W, Humphreys M, Wilson D, Zumstein L, Lemoine NR, Neoptolemos JP: Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo. Gene The 8:199-208, 2001
-
(2001)
Gene the
, vol.8
, pp. 199-208
-
-
Ghaneh, P.1
Greenhalf, W.2
Humphreys, M.3
Wilson, D.4
Zumstein, L.5
Lemoine, N.R.6
Neoptolemos, J.P.7
-
13
-
-
0032792828
-
Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells
-
Kusumoto M,Ogawa T, Mizumoto K, Ueno H, Niiyama H, Sato N, Nakamura M, Tanaka M: Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells. Clin Cancer Res 5:2140-2147, 1999
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2140-2147
-
-
Kusumoto, M.1
Ogawa, T.2
Mizumoto, K.3
Ueno, H.4
Niiyama, H.5
Sato, N.6
Nakamura, M.7
Tanaka, M.8
-
14
-
-
0037127220
-
Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2
-
Ahmed MM, Alcock RA, Chendil D, Dey S, Das A, Venkatasubbarao K, Mohiuddin M, Sun L, Strodel WE, Freeman JW: Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2. J Biol Chem 277:2234-2246, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 2234-2246
-
-
Ahmed, M.M.1
Alcock, R.A.2
Chendil, D.3
Dey, S.4
Das, A.5
Venkatasubbarao, K.6
Mohiuddin, M.7
Sun, L.8
Strodel, W.E.9
Freeman, J.W.10
-
15
-
-
0035067212
-
Treatment based on a combination of CYP2B1/cyclophosphamide system and p53 delivery enhances tumour regression in human pancreatic cancer
-
Mercade E, Cascallo M, Carrio M, Calbo J, Gomez-Trevino A, Fillat C, Gomez-Foix AM, Mazo A: Treatment based on a combination of CYP2B1/ cyclophosphamide system and p53 delivery enhances tumour regression in human pancreatic cancer. Ann Oncol 12:379-388, 2001
-
(2001)
Ann Oncol
, vol.12
, pp. 379-388
-
-
Mercade, E.1
Cascallo, M.2
Carrio, M.3
Calbo, J.4
Gomez-Trevino, A.5
Fillat, C.6
Gomez-Foix, A.M.7
Mazo, A.8
-
16
-
-
0034102707
-
Ki-ras point mutation and p53 expression in human pancreatic cancer: A comparative study among Chinese, Japanese and Western patients
-
Dong M, Nio Y, Tamura K, Song MM, Guo KJ, Guo RX, Dong YT: Ki-ras point mutation and p53 expression in human pancreatic cancer: A comparative study among Chinese, Japanese and Western patients. Cancer Epidemiol Biomark Prev 9:273-284, 2000
-
(2000)
Cancer Epidemiol Biomark Prev
, vol.9
, pp. 273-284
-
-
Dong, M.1
Nio, Y.2
Tamura, K.3
Song, M.M.4
Guo, K.J.5
Guo, R.X.6
Dong, Y.T.7
-
17
-
-
0032901753
-
Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to diagnosis of patients with pancreatic cancer: Comparison with K-ras mutation
-
Yamaguchi Y, Watanabe H, Yrdiran S, Ohtsubo K, Motoo Y, Okai T, Sawabu N: Detection of mutations of p53 tumor suppressor gene in pancreatic juice and its application to diagnosis of patients with pancreatic cancer: Comparison with K-ras mutation. Clin Cancer Res 5:1147-1153, 1999
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1147-1153
-
-
Yamaguchi, Y.1
Watanabe, H.2
Yrdiran, S.3
Ohtsubo, K.4
Motoo, Y.5
Okai, T.6
Sawabu, N.7
-
18
-
-
0033869440
-
Ki-ras codon 12 point and p53 mutations: A molecular examination of the main tumor, liver, portal vein, peripheral arterial blood and para-aortic lymph node in pancreatic cancer
-
Yamaguchi K, Chijiiwa K, Torato N, Kinoshita M, Tanaka M: Ki-ras codon 12 point and p53 mutations: A molecular examination of the main tumor, liver, portal vein, peripheral arterial blood and para-aortic lymph node in pancreatic cancer. Am J Gastroenterol 95:1939-1945, 2000
-
(2000)
Am J Gastroenterol
, vol.95
, pp. 1939-1945
-
-
Yamaguchi, K.1
Chijiiwa, K.2
Torato, N.3
Kinoshita, M.4
Tanaka, M.5
-
19
-
-
0033508689
-
An immunohistochemical study of the expression of bcl-2 and p53 oncoproteins in pancreatic intraepithelial neoplastic and pancreatic cancer
-
Tomaszewska R, Karcz D, Stachura J: An immunohistochemical study of the expression of bcl-2 and p53 oncoproteins in pancreatic intraepithelial neoplastic and pancreatic cancer. Int J Pancreatol 26:163-171, 1999
-
(1999)
Int J Pancreatol
, vol.26
, pp. 163-171
-
-
Tomaszewska, R.1
Karcz, D.2
Stachura, J.3
-
20
-
-
0030183051
-
Tumor suppressor activity of the TGF-beta pathway in human cancers
-
Markowitz SD, Roberts AB, Lang SA, Kersting M, Baumann R, Wild A, Moll R, Rothmund M, Bartsch DK: Tumor suppressor activity of the TGF-beta pathway in human cancers. Cytokine Growth Factor Rev 7:93-102, 1996
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, pp. 93-102
-
-
Markowitz, S.D.1
Roberts, A.B.2
Lang, S.A.3
Kersting, M.4
Baumann, R.5
Wild, A.6
Moll, R.7
Rothmund, M.8
Bartsch, D.K.9
-
21
-
-
0036006684
-
p16INK4a, is a prognostic marker in resected ductal pancreatic cancer: An analysis of p16INK4a, p53,MDM2, an Rb
-
Gerdes B, Ramaswamy A, Ziegler A, Lang SA, Kersting M, Baumann R, Wild A, Moll R, Rothmund M, Bartsch DK: p16INK4a, is a prognostic marker in resected ductal pancreatic cancer: An analysis of p16INK4a, p53,MDM2, an Rb. Ann Surg 235:51-59, 2002
-
(2002)
Ann Surg
, vol.235
, pp. 51-59
-
-
Gerdes, B.1
Ramaswamy, A.2
Ziegler, A.3
Lang, S.A.4
Kersting, M.5
Baumann, R.6
Wild, A.7
Moll, R.8
Rothmund, M.9
Bartsch, D.K.10
-
22
-
-
0033497531
-
Sequential accumulation of K-ras mutation and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy
-
Jimenez RE, Warshaw AL, Zgraggen K, Hartwig W, Taylor DZ, Compton CC, Fernandez-del Castillo: Sequential accumulation of K-ras mutation and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy. Ann Surg 230:501-509, 1999
-
(1999)
Ann Surg
, vol.230
, pp. 501-509
-
-
Jimenez, R.E.1
Warshaw, A.L.2
Zgraggen, K.3
Hartwig, W.4
Taylor, D.Z.5
Compton, C.C.6
Fernandez-del Castillo7
-
23
-
-
0037128687
-
Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma
-
Sarela AI, Verbeke CS, Ramsdale J, Davies CL, Markham AF, Guillou PJ: Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br J Cancer 86:886-892, 2002
-
(2002)
Br J Cancer
, vol.86
, pp. 886-892
-
-
Sarela, A.I.1
Verbeke, C.S.2
Ramsdale, J.3
Davies, C.L.4
Markham, A.F.5
Guillou, P.J.6
-
24
-
-
0032767855
-
Molecular aspects of pancreatic cancer and future perspectives
-
Friess H, Kleeff J, Korc M, Buchler MW: Molecular aspects of pancreatic cancer and future perspectives. Dig Surg 16:281-290, 1999
-
(1999)
Dig Surg
, vol.16
, pp. 281-290
-
-
Friess, H.1
Kleeff, J.2
Korc, M.3
Buchler, M.W.4
-
25
-
-
0027131252
-
Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival
-
Friess H, Yamanaka Y, Buchler M, Ebert M, Beger HG, Gold LI, Korc M: Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 105:1846-1856, 1993
-
(1993)
Gastroenterology
, vol.105
, pp. 1846-1856
-
-
Friess, H.1
Yamanaka, Y.2
Buchler, M.3
Ebert, M.4
Beger, H.G.5
Gold, L.I.6
Korc, M.7
-
26
-
-
0034648528
-
TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation
-
Giehl K, Seidel B, Gierschik P, Adler G, Menke A: TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation. Oncoge 19:4531-4541, 2000
-
(2000)
Oncoge
, vol.19
, pp. 4531-4541
-
-
Giehl, K.1
Seidel, B.2
Gierschik, P.3
Adler, G.4
Menke, A.5
-
27
-
-
0033623872
-
Disruption of TGFbeta signaling pathways in human pancreatic cancer cells
-
Simeone DM, Pham T, Logsdon CD: Disruption of TGFbeta signaling pathways in human pancreatic cancer cells. Ann Surg 232:73-80, 2000
-
(2000)
Ann Surg
, vol.232
, pp. 73-80
-
-
Simeone, D.M.1
Pham, T.2
Logsdon, C.D.3
-
28
-
-
0033598408
-
The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer
-
Kleeff J, Ishiwata T, Marayama H, Friess H, Truong P, Buchler MW, Falb D, Korc M: The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. Oncogene 18:5363-5372, 1999
-
(1999)
Oncogene
, vol.18
, pp. 5363-5372
-
-
Kleeff, J.1
Ishiwata, T.2
Marayama, H.3
Friess, H.4
Truong, P.5
Buchler, M.W.6
Falb, D.7
Korc, M.8
-
29
-
-
0034067359
-
Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma
-
Venkatasubbarao K, Ahmed MM, Mohiuddin M, Swiderski C, Lee E, Gower WR Jr, Salhab KF, McGrath P, Strodel W, Freeman JW: Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma. Anticancer Res 20:43-51, 2000
-
(2000)
Anticancer Res
, vol.20
, pp. 43-51
-
-
Venkatasubbarao, K.1
Ahmed, M.M.2
Mohiuddin, M.3
Swiderski, C.4
Lee, E.5
Gower Jr., W.R.6
Salhab, K.F.7
McGrath, P.8
Strodel, W.9
Freeman, J.W.10
-
30
-
-
0032711157
-
Enhanced expression of the type II transforming growth factor b receptor is associated with decreased survival in human pancreatic cancer
-
Wagner M, Kleeff J, Friess H, Buchler M, Korc M: Enhanced expression of the type II transforming growth factor b receptor is associated with decreased survival in human pancreatic cancer. Pancreas 19:370-376, 1999
-
(1999)
Pancreas
, vol.19
, pp. 370-376
-
-
Wagner, M.1
Kleeff, J.2
Friess, H.3
Buchler, M.4
Korc, M.5
-
31
-
-
0030715078
-
Clinical utility of endoscopie ultrasound-guided fine needle aspiration
-
Erickson RA, Sayage-Rabie L, Avots-Avotins A: Clinical utility of endoscopie ultrasound-guided fine needle aspiration. Acta Cytol 41:1647-1653, 1997
-
(1997)
Acta Cytol
, vol.41
, pp. 1647-1653
-
-
Erickson, R.A.1
Sayage-Rabie, L.2
Avots-Avotins, A.3
-
32
-
-
0033980883
-
Factors predicting the number of EUS-guided fine needle passes for diagnosis of pancreatic malignancies
-
Erickson RA, Sayage-Rabie L, Beisner RS: Factors predicting the number of EUS-guided fine needle passes for diagnosis of pancreatic malignancies. Gastrointest Endosc 51:184-190, 2000
-
(2000)
Gastrointest Endosc
, vol.51
, pp. 184-190
-
-
Erickson, R.A.1
Sayage-Rabie, L.2
Beisner, R.S.3
-
33
-
-
0033998601
-
Transforming growth-factor beta1 acts as a potent inhibitor of complement C3 biosynthesis in human pancreatic cancer cell lines
-
Andoh A, Shimada M, Takaya H, Hata K, Fujiyama Y, Bamba T: Transforming growth-factor beta1 acts as a potent inhibitor of complement C3 biosynthesis in human pancreatic cancer cell lines. Pancreas 20:138-145, 2000
-
(2000)
Pancreas
, vol.20
, pp. 138-145
-
-
Andoh, A.1
Shimada, M.2
Takaya, H.3
Hata, K.4
Fujiyama, Y.5
Bamba, T.6
|