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Volumn 24, Issue 7, 2004, Pages 1240-1245

Enhanced P2X7 activity in human fibroblasts from diabetic patients: A possible pathogenetic mechanism for vascular damage in diabetes

Author keywords

Apoptosis; Atherosclerosis; Cytokines; Diabetes; Fibroblasts; P2 receptors

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; FIBRONECTIN; INTERLEUKIN 6; PURINE P2X7 RECEPTOR; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2',3' DIALDEHYDE ATP; 2',3'-DIALDEHYDE ATP; 3' O (4 BENZOYL)BENZOYLADENOSINE 5' TRIPHOSPHATE; 3'-O-(4-BENZOYL)BENZOYLADENOSINE 5'-TRIPHOSPHATE; ADENOSINE DIPHOSPHATE; APYRASE; CYTIDINE TRIPHOSPHATE; DRUG DERIVATIVE; PURINE P2 RECEPTOR; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAL PHOSPHATE-6-AZOPHENYL-2',4'-DISULFONIC ACID; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

EID: 3042814728     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000133193.11078.c0     Document Type: Article
Times cited : (41)

References (47)
  • 1
    • 0003054841 scopus 로고    scopus 로고
    • Potential role of the adventitia in arteritis and atherosclerosis
    • Wilcox JN, Scott NA. Potential role of the adventitia in arteritis and atherosclerosis. Int J Cardiol. 1996;54:S21-S35.
    • (1996) Int J Cardiol , vol.54
    • Wilcox, J.N.1    Scott, N.A.2
  • 2
    • 0034111839 scopus 로고    scopus 로고
    • Adventitial fibroblasts: Defining a role in vessel wall remodeling
    • Strauss BH, Rabinovitch M. Adventitial fibroblasts: defining a role in vessel wall remodeling. Am J Respir Cell Mol Biol. 2000;22:1-3.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 1-3
    • Strauss, B.H.1    Rabinovitch, M.2
  • 5
    • 0031736547 scopus 로고    scopus 로고
    • Biology of scleroderma fibroblast
    • Strehlow D, Korn JH. Biology of scleroderma fibroblast. Curr Opin Rheumatol. 1998;10:572-578.
    • (1998) Curr Opin Rheumatol , vol.10 , pp. 572-578
    • Strehlow, D.1    Korn, J.H.2
  • 7
    • 0035824921 scopus 로고    scopus 로고
    • Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: From innocent bystander to active participant
    • Sartore S, Chiavegato A, Faggin E, Franch R, Puato M, Ausoni S, Pauletto P. Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: from innocent bystander to active participant. Circ Res. 2001;89:1111-1121.
    • (2001) Circ Res , vol.89 , pp. 1111-1121
    • Sartore, S.1    Chiavegato, A.2    Faggin, E.3    Franch, R.4    Puato, M.5    Ausoni, S.6    Pauletto, P.7
  • 8
    • 0003054841 scopus 로고    scopus 로고
    • Potential role of the adventitia in arteritis and atherosclerosis
    • Wilcox JN, Scott NA. Potential role of the adventitia in arteritis and atherosclerosis. Int J Cardiol. 1996;54:S21-S35.
    • (1996) Int J Cardiol , vol.54
    • Wilcox, J.N.1    Scott, N.A.2
  • 10
    • 0032033139 scopus 로고    scopus 로고
    • The regulation of vascular function by P2 receptors: Multiple sites and multiple receptors
    • Boarder MR, Hourani SM. The regulation of vascular function by P2 receptors: multiple sites and multiple receptors. Trends Pharmacol Sci. 1998;19:99-107.
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 99-107
    • Boarder, M.R.1    Hourani, S.M.2
  • 11
    • 0036118418 scopus 로고    scopus 로고
    • Purinergic signaling and vascular cell proliferation and death
    • Bunstock G. Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol. 2002;22:364-373.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 364-373
    • Bunstock, G.1
  • 12
    • 0032587490 scopus 로고    scopus 로고
    • P2U receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats
    • You J, Johnson TD, Marrelli SP, Mombouli JV, Bryan RM Jr. P2U receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats. Stroke. 1999:30:1125-1133.
    • (1999) Stroke , vol.30 , pp. 1125-1133
    • You, J.1    Johnson, T.D.2    Marrelli, S.P.3    Mombouli, J.V.4    Bryan Jr., R.M.5
  • 13
    • 0026614118 scopus 로고
    • Atp Activates P2X-contracting P2Y-relaxing purinoceptors in the smooth muscle of mouse vas deferens
    • Boland B, Himpens B, Vincent MF, Gillis JM, Casteels R. ATP activates P2X-contracting and P2Y-relaxing purinoceptors in the smooth muscle of mouse vas deferens. Br J Pharmacol. 1992;107:1152-1158.
    • (1992) Br J Pharmacol , vol.107 , pp. 1152-1158
    • Boland, B.1    Himpens, B.2    Vincent, M.F.3    Gillis, J.M.4    Casteels, R.5
  • 14
    • 0028909570 scopus 로고
    • ATP induces the release of IL-1 from LPS-primed cells in vivo
    • Griffiths RJ, Stam EJ, Downs JT, Otterness IG, ATP induces the release of IL-1 from LPS-primed cells in vivo. J Immunol. 1995;154:2821-2828.
    • (1995) J Immunol , vol.154 , pp. 2821-2828
    • Griffiths, R.J.1    Stam, E.J.2    Downs, J.T.3    Otterness, I.G.4
  • 16
    • 0026782311 scopus 로고
    • Extracellular ATP and ADP stimulate proliferation of porcine aortic smooth muscle cells
    • Wang DJ, Huang NN, Heppel LA. Extracellular ATP and ADP stimulate proliferation of porcine aortic smooth muscle cells. J Cell Physiol. 1992;153:221-233.
    • (1992) J Cell Physiol , vol.153 , pp. 221-233
    • Wang, D.J.1    Huang, N.N.2    Heppel, L.A.3
  • 17
    • 0024432180 scopus 로고    scopus 로고
    • Responses of mouse lymphocytes to extracellular adenosine 5′-triphosphate (ATP). Lymphocytes with cytotoxic activity are resistant to the permeabilizing effects of ATP
    • Di Virgilio F, Bronte V, Collavo D, Zanovello P. Responses of mouse lymphocytes to extracellular adenosine 5′-triphosphate (ATP). Lymphocytes with cytotoxic activity are resistant to the permeabilizing effects of ATP. J Immunol. 1999;143:1955-1960.
    • (1999) J Immunol , vol.143 , pp. 1955-1960
    • Di Virgilio, F.1    Bronte, V.2    Collavo, D.3    Zanovello, P.4
  • 18
    • 0033680583 scopus 로고    scopus 로고
    • P2 purinergic receptors: Modulation of cell function and therapeutic potential
    • Burnstock G, Williams M. P2 purinergic receptors: modulation of cell function and therapeutic potential. J Pharmacol Exp Ther. 2000;295:862-969.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 862-969
    • Burnstock, G.1    Williams, M.2
  • 19
    • 0031754497 scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev. 1988;50:413-492.
    • (1988) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 21
    • 0023644626 scopus 로고    scopus 로고
    • Extracellular ATP4 promotes cation fluxes in the J774 mouse macrophage cell line
    • Steinberg TH, Silverstein SC. Extracellular ATP4 promotes cation fluxes in the J774 mouse macrophage cell line. J Biol Chem. 1997;262:3118-3122.
    • (1997) J Biol Chem , vol.262 , pp. 3118-3122
    • Steinberg, T.H.1    Silverstein, S.C.2
  • 22
    • 0023664593 scopus 로고
    • ATP4 permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes
    • Steinberg TH, Newman AS, Swanson JA, Silverstein SC. ATP4 permeabilizes the plasma membrane of mouse macrophages to fluorescent dyes. J Biol Chem. 1987;262:8884-8888.
    • (1987) J Biol Chem , vol.262 , pp. 8884-8888
    • Steinberg, T.H.1    Newman, A.S.2    Swanson, J.A.3    Silverstein, S.C.4
  • 23
    • 0028850665 scopus 로고
    • The P2Z purinoceptor: An intriguing role in immunità, inflammation and cell death
    • Di Virgilio F. The P2Z purinoceptor: an intriguing role in immunità, inflammation and cell death. Immunol Today. 1995;16:524-528.
    • (1995) Immunol Today , vol.16 , pp. 524-528
    • Di Virgilio, F.1
  • 27
    • 0028985997 scopus 로고
    • The purinegic receptor of human macrophage cells, Characterization and possible physiological role
    • Falzoni S, Munerati M, Ferrari D, Spisani S, Moretti S, Di Virgilio F. The purinegic receptor of human macrophage cells, Characterization and possible physiological role. J Clin Invest. 1995;95:1207-1216.
    • (1995) J Clin Invest , vol.95 , pp. 1207-1216
    • Falzoni, S.1    Munerati, M.2    Ferrari, D.3    Spisani, S.4    Moretti, S.5    Di Virgilio, F.6
  • 31
    • 0024452835 scopus 로고
    • Accumulation of fibronectin in aortas from diabetic patients. A quantitative immunohistochemical and biochemical study
    • Rasmussen LM, Heickendorff L. Accumulation of fibronectin in aortas from diabetic patients. A quantitative immunohistochemical and biochemical study. Lab Invest. 1989;61:440-446.
    • (1989) Lab Invest , vol.61 , pp. 440-446
    • Rasmussen, L.M.1    Heickendorff, L.2
  • 32
    • 0031055514 scopus 로고    scopus 로고
    • Interaction of endothelial cells and fibroblasts with modified fibrin networks: Role in atherosclerosis
    • Shats EA, Nair CH, Dhall DP. Interaction of endothelial cells and fibroblasts with modified fibrin networks: role in atherosclerosis. Atherosclerosis. 1997;29:9-15.
    • (1997) Atherosclerosis , vol.29 , pp. 9-15
    • Shats, E.A.1    Nair, C.H.2    Dhall, D.P.3
  • 33
    • 0030955004 scopus 로고    scopus 로고
    • Intracellular free calcium abnormalities in fibroblasts from non-insulin-dependent diabetic patients with and without hypertension
    • Duner E, Di Virgilio F, Trevisan R, Cipollina MR, Crepaldi G, Nosadini R. Intracellular free calcium abnormalities in fibroblasts from non-insulin-dependent diabetic patients with and without hypertension. Hypertension. 1997;29:1007-1013.
    • (1997) Hypertension , vol.29 , pp. 1007-1013
    • Duner, E.1    Di Virgilio, F.2    Trevisan, R.3    Cipollina, M.R.4    Crepaldi, G.5    Nosadini, R.6
  • 34
    • 0038114530 scopus 로고    scopus 로고
    • Cardiovascular disease: Much more aggressive in patients with type 2 diabetes
    • Chiquette E, Chilton R. Cardiovascular disease: much more aggressive in patients with type 2 diabetes. Curr Atheroscler Rep. 2002;4:134-142.
    • (2002) Curr Atheroscler Rep , vol.4 , pp. 134-142
    • Chiquette, E.1    Chilton, R.2
  • 35
    • 0029901505 scopus 로고    scopus 로고
    • Cytokines, modified lipoproteins and arteriosclerosis in diabetes
    • Lopes-Virella MF, Virella G. Cytokines, modified lipoproteins and arteriosclerosis in diabetes. Diabetes. 1996;45(suppl 3):S40-S44.
    • (1996) Diabetes , vol.45 , Issue.SUPPL. 3
    • Lopes-Virella, M.F.1    Virella, G.2
  • 36
    • 0036226795 scopus 로고    scopus 로고
    • Fibroblasts derived from chronic diabetic ulcers differ in their response to stimulation with EGF, IGF-I, bFGF and PDGF-AB compared to controls
    • Loot MA, Kenter SB, Au FL, van Galen WJ, Middelkoop E, Bos JD, Mekkes JR. Fibroblasts derived from chronic diabetic ulcers differ in their response to stimulation with EGF, IGF-I, bFGF and PDGF-AB compared to controls. Eur J Cell Biol. 2002;81:153-160.
    • (2002) Eur J Cell Biol , vol.81 , pp. 153-160
    • Loot, M.A.1    Kenter, S.B.2    Au, F.L.3    Van Galen, W.J.4    Middelkoop, E.5    Bos, J.D.6    Mekkes, J.R.7
  • 37
    • 0035047352 scopus 로고    scopus 로고
    • Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein related protein 2) in human fibroblasts: A potential mechanism for expansion of extracellular matrix in diabetes mellitus
    • Twigg SM, Chen MM, Joly AH, Chakrapani SD, Tsubaki J, Kim HS, Oh Y, Rosenfeld RG. Advanced glycosylation end products up-regulate connective tissue growth factor (insulin-like growth factor-binding protein related protein 2) in human fibroblasts: a potential mechanism for expansion of extracellular matrix in diabetes mellitus. Endocrinology. 2001;142:1760-1769.
    • (2001) Endocrinology , vol.142 , pp. 1760-1769
    • Twigg, S.M.1    Chen, M.M.2    Joly, A.H.3    Chakrapani, S.D.4    Tsubaki, J.5    Kim, H.S.6    Oh, Y.7    Rosenfeld, R.G.8
  • 38
    • 0031717546 scopus 로고    scopus 로고
    • Increased release of ATP from endothelial cells during inflammation
    • Bodin P, Burnstock G. Increased release of ATP from endothelial cells during inflammation. Inflamm Res. 1998;47:351-354.
    • (1998) Inflamm Res , vol.47 , pp. 351-354
    • Bodin, P.1    Burnstock, G.2
  • 39
    • 0036102125 scopus 로고    scopus 로고
    • CD39 is the dominant Langerhans cell-associated ecto-NTDPase: Modulatory roles in inflammation and immune responsiveness
    • Mizumoto N, Kumamoto T, Robson SC, Sevigny J, Matsue H, Enjyoji K, Takashima A. CD39 is the dominant Langerhans cell-associated ecto-NTDPase: modulatory roles in inflammation and immune responsiveness. Nat Med. 2002;8:358-365.
    • (2002) Nat Med , vol.8 , pp. 358-365
    • Mizumoto, N.1    Kumamoto, T.2    Robson, S.C.3    Sevigny, J.4    Matsue, H.5    Enjyoji, K.6    Takashima, A.7
  • 40
    • 0036371001 scopus 로고    scopus 로고
    • Potential therapeutic targets in the rapidly expanding field of purinergic signaling
    • Burnstock G. Potential therapeutic targets in the rapidly expanding field of purinergic signaling. Clin Med. 2002;2:45-53.
    • (2002) Clin Med , vol.2 , pp. 45-53
    • Burnstock, G.1
  • 41
    • 0036080541 scopus 로고    scopus 로고
    • Focus on "extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells"
    • Dubyak GR. Focus on "extracellular ATP signaling and P2X nucleotide receptors in monolayers of primary human vascular endothelial cells." Am J Physiol Cell Physiol. 2002;282:C242-C244.
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Dubyak, G.R.1
  • 42
    • 0343120744 scopus 로고
    • 2 or products of activated neutrophils
    • 2 or products of activated neutrophils. Am J Med. 1991;91:89S-94S.
    • (1991) Am J Med , vol.91
    • Ward, P.A.1
  • 43
    • 0036185091 scopus 로고    scopus 로고
    • P2 receptors: New potential players in atherosclerosis
    • Di Virgilio F, Solini A. P2 receptors: new potential players in atherosclerosis. Br J Pharmacol. 2002;135:831-842.
    • (2002) Br J Pharmacol , vol.135 , pp. 831-842
    • Di Virgilio, F.1    Solini, A.2
  • 47
    • 0032978142 scopus 로고    scopus 로고
    • The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo
    • Guevara NV, Kim HS, Antonova EI, Chan L. The absence of p53 accelerates atherosclerosis by increasing cell proliferation in vivo. Nat Med. 1999;5:335-339.
    • (1999) Nat Med , vol.5 , pp. 335-339
    • Guevara, N.V.1    Kim, H.S.2    Antonova, E.I.3    Chan, L.4


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